Mechanisms of vasomotor rhinitis.

abstract：:The purpose of this study was to investigate whether uncontrolled asthma was associated with healthcare outcomes among Latin American patients with asthma. We used data from 2168 patients with asthma who participated in the 2011 Latin America Asthma Insights and Management (AIM) survey. Using Global Initiative for Ast...

journal_title：Allergy

authors： Gold LS,Montealegre F,Allen-Ramey FC,Jardim J,Smith N,Sansores R,Sullivan SD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The association between cigarette smoke exposure and allergic airway disease is a matter for debate. We sought to investigate in an in vitro system whether active smoking reduces the integrity and barrier function of the respiratory epithelium and thus facilitates allergen penetration. METHODS:We cultured t...

journal_title：Allergy

authors： Gangl K,Reininger R,Bernhard D,Campana R,Pree I,Reisinger J,Kneidinger M,Kundi M,Dolznig H,Thurnher D,Valent P,Chen KW,Vrtala S,Spitzauer S,Valenta R,Niederberger V

更新日期：2009-03-01 00:00:00

abstract：:Micro-organisms constantly invade the human body and may form a threat to our health. Traditionally, concepts of defence mechanisms have included a protective outer layer of epithelia and a vigilant immune system searching for areas where the integrity of the outer layer may be compromised. Instead of considering thes...

journal_title：Allergy

authors： van Tongeren J,Reinartz SM,Fokkens WJ,de Jong EC,van Drunen CM

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Outside clinical trials, data on systemic reactions (SRs) due to allergen immunotherapy (AIT) are scarce. METHODS:A prospective, longitudinal, web-based survey of 'real-life' respiratory allergen immunotherapy (AIT) clinical practice was conducted in France, Germany and Spain. SRs were recorded and coded ac...

journal_title：Allergy

authors： Calderón MA,Vidal C,Rodríguez Del Río P,Just J,Pfaar O,Tabar AI,Sánchez-Machín I,Bubel P,Borja J,Eberle P,Reiber R,Bouvier M,Lepelliez A,Klimek L,Demoly P,EASSI Doctors' Group.

更新日期：2017-03-01 00:00:00

abstract：:The presence of viable mold propagules in house dust was investigated by 10 different analytic methods, in order to determine to what extent different results are obtained when different analytic methods are used. Moreover, the value of this measurement as an estimator of the potential exposure to fungi in epidemiolog...

journal_title：Allergy

authors： Verhoeff AP,van Reenen-Hoekstra ES,Samson RA,Brunekreef B,van Wijnen JH

更新日期：1994-08-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Little is known about the diagnostic approaches for immediate hypersensitivity reactions (IHRs) due to 5-nitroimidazole antibiotics. The aim was to evaluate the usefulness of in vivo tests and basophil activation test (BAT) for the diagnosis of IHRs due to metronidazole and ornidazole and to determine possib...

journal_title：Allergy

authors： Beyaz Ş,Akdeniz N,Yılmaz A,Demir S,Öztop N,Çolakoğlu B,Büyüköztürk S,Deniz G,Gelincik A

更新日期：2020-08-05 00:00:00

abstract：:Although H1 antihistamine compounds (H1) are highly effective in the treatment of allergic rhinitis (AR), their role in the treatment of asthma is still controversial. Because a strong association between AR and bronchial hyperresponsiveness (BHR) has been reported, this study was designed to assess the effect of a ne...

journal_title：Allergy

authors： Aubier M,Neukirch C,Peiffer C,Melac M

更新日期：2001-01-01 00:00:00

abstract：:Chip pile workers are exposed to high concentrations of airborne mould spores. Few sporadic cases of allergic alveolitis have been reported in Finland. Eight non-smoking workers, six on chip piles and two on bark piles, were examined to study the immunological and clinical response to continuous mould spore exposure. ...

journal_title：Allergy

authors： Jäppinen P,Haahtela T,Liira J

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Involvement of paranasal sinuses has been suggested in allergic rhinitis but not clearly demonstrated. AIMS:To investigate the relationship between intermittent allergic rhinitis and computerized tomography (CT). METHODS:Twenty patients with intermittent rhinitis and sensitized to cypress pollens underwent...

journal_title：Allergy

authors： Piette V,Bousquet C,Kvedariene V,Dhivert-Donnadieu H,Crampette L,Senac JP,Bousquet J,Demoly P

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34(+) hemopoietic progenitor cells (HPC). Depending on the stage of maturation and the environment, MC variably express differentiation- and activation-linked antigens. Little is known, however, about the ...

journal_title：Allergy

authors： Schernthaner GH,Hauswirth AW,Baghestanian M,Agis H,Ghannadan M,Worda C,Krauth MT,Printz D,Fritsch G,Sperr WR,Valent P

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Blomia tropicalis is an important mite species in the tropical and sub-tropical regions of the world. Blo t 5 is the major allergen with up to 70% sensitization rates in B. tropicalis allergic populations. METHODS:Mice were immunized intramuscularly with naked plasmid DNA encoding Blo t 5 gene with in vivo ...

journal_title：Allergy

authors： Yi FC,Lee BW,Cheong N,Chua KY

更新日期：2005-01-01 00:00:00

abstract：:The diagnosis of allergic reactions in clinical practice is based on both clinical history and the determination of specific immunoglobulin E (IgE), either in the serum or on skin mast cells. However, for various reasons, identification of the causative factors is not possible in all the cases. Moreover, not all aller...

journal_title：Allergy

authors： Demoly P,Lebel B,Arnoux B

更新日期：2003-07-01 00:00:00

abstract：:Eosinophil cationic protein (ECP) is a cationic protein secreted by eosinophils with toxic properties for the respiratory epithelium. Sputum-ECP levels have been shown to correlate inversely with airflow obstruction in asthma. In the present study we investigated whether ECP concentrations are different between asthma...

journal_title：Allergy

authors： Virchow JC Jr,Kroegel C,Hage U,Kortsik C,Matthys H,Werner P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The differential diagnosis of eosinophilic gastroenteritis (EG) includes, among other diseases, parasitic infections such as anisakiasis, which has acquired worldwide importance. METHODS:We reviewed all patients referred to our allergy service who had been diagnosed as having primary EG to determine the pos...

journal_title：Allergy

authors： Gómez B,Tabar AI,Tuñón T,Larrínaga B,Alvarez MJ,García BE,Olaguibel JM

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Allergy to pollen from gymnosperms is well documented in the West. However, many allergenic species are native to the Himalayan region of India, and Cedrus deodara (Pinaceae) was selected for allergologic investigation. The objective was to define the allergologic and immunochemical aspects of C. deodara pol...

journal_title：Allergy

authors： Rawat A,Singh A,Singh AB,Gaur SN,Kumar L,Roy I,Ravindrun P

更新日期：2000-07-01 00:00:00

abstract：:The ability of common environmental allergens to stimulate IgE responses and thus to produce allergic diseases has tended to overshadow the fact that helminthic parasites are possibly the most potent inducers of this immunoglobulin that exists in nature. Although it has been well established that during these infectio...

journal_title：Allergy

authors： Mingomataj EC,Xhixha F,Gjata E

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total serum IgE l...

journal_title：Allergy

authors： Tewfik MA,Bossé Y,Lemire M,Hudson TJ,Vallée-Smejda S,Al-Shemari H,Laprise C,Desrosiers M

更新日期：2009-05-01 00:00:00

abstract：:This is a description of the Study of Asthma, Genes and the Environment (SAGE), a novel birth cohort created from provincial healthcare administrative records. It is a general population-based cohort, composed of children at high and low risk for asthma, living in urban and rural environments in Manitoba, Canada. The ...

journal_title：Allergy

authors： Kozyrskyj AL,HayGlass KT,Sandford AJ,Paré PD,Chan-Yeung M,Becker AB

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The cytokine network is thought to be essential in orchestrating airway inflammation in asthma. Although evidence has accumulated to suggest that atopic asthma is a Th2 disease, much less is known about nonatopic asthma. METHODS:We have compared the production of IL-4, IL-6, IFN-gamma, and TNF-alpha from pe...

journal_title：Allergy

authors： Bettiol J,Bartsch P,Louis R,De Groote D,Gevaerts Y,Louis E,Malaise M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Because little is known about the effects of asthma and asthma therapy on lipid and protein metabolism, we have investigated the characteristics of diet and plasma/serum levels of fat and protein in a group of asthma patients with various degrees of severity. METHODS:A case-control study was carried out on ...

journal_title：Allergy

authors： Picado C,Deulofeu R,Lleonart R,Agustí M,Casals E,Quintó L,Mullol J

更新日期：1999-06-01 00:00:00

abstract：:Ketotifen is marketed throughout the world as an antiallergy drug, but whether it affects infiltration of inflammatory cells into airway mucosa is not known. We studied the effects of ketotifen on symptoms, pulmonary function, and airway inflammation in 25 patients with atopic asthma. Patients took ketotifen (1 mg twi...

journal_title：Allergy

authors： Hoshino M,Nakamura Y,Shin Z,Fukushima Y

更新日期：1997-08-01 00:00:00

abstract：:Although mediators, such as lipids, cytokines, and chemokines, are related to the appearance of an IPR, there has been no reliable indicator to predict conditions for the appearance of an IPR. In this study, we adopted a proteomic approach to investigate the pathogenesis at the level of the plasma proteins and to deve...

journal_title：Allergy

authors： Rhim T,Choi YS,Nam BY,Uh ST,Park JS,Kim YH,Paik YK,Park CS

更新日期：2009-01-01 00:00:00

abstract：:Oral immunotherapy (IT) was evaluated in a pilot study in two centres in children aged 8-15 years with allergic rhinoconjunctivitis. High doses (up to 20 X 10(6) BU monthly) of a defined freeze-dried birch pollen extract administered in enteric-coated gelatine capsules were given either daily for seven consecutive day...

journal_title：Allergy

authors： Björkstén B,Möller C,Broberger U,Ahlstedt S,Dreborg S,Johansson SG,Juto P,Lanner A

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific in...

journal_title：Allergy

authors： Pignatti P,Perfetti L,Galdi E,Pozzi V,Bossi A,Biale C,Moscato G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Bronchial, nasal, and conjunctival challenges are useful for clarifying discordant clinical history (Hx) and skin and/or serologic tests and in assessing semiquantitative changes in biologic sensitivity over time. The objective of this study was to determine the safety and reproducibility of repeated latex-a...

journal_title：Allergy

authors： Kurtz KM,Hamilton RG,Schaefer JA,Primeau MN,Adkinson NF Jr

更新日期：2001-09-01 00:00:00

abstract：:Skin tests and estimation of specific IgE-antibodies by the RAST are evaluated as diagnostic procedures in bee sting hypersensitivity with the followiny extracts. (2) With bee venom results of skin tests and RAST correspond in 82%, with bee wholebody extracts in 68%. (3) Both with skin tests and the RAST with bee veno...

journal_title：Allergy

authors： Patrizzi R,Müller U,Yman L,Hoigné R

更新日期：1979-08-01 00:00:00

abstract：:Twenty-nine patients with asthma and aspirin-sensitivity were studied in an attempt to induce tolerance to aspirin (ASA). Starting with the smallest ASA doses eliciting bronchial obstruction (threshold doses) we doubled the doses on subsequent days and finally achieved good tolerance of 600 mg ASA per day in 27 patien...

journal_title：Allergy

authors： Kowalski ML,Grzelewska-Rzymowska I,Rozniecki J,Szmidt M

更新日期：1984-04-01 00:00:00

abstract：:House dust mites (HDMs) are sources of an extensive repertoire of allergens responsible for a range of allergic conditions. Technological advances have accelerated the identification of these allergens and characterized their putative roles within HDMs. Understanding their functional bioactivities is illuminating how ...

journal_title：Allergy

authors： Jacquet A,Robinson C

更新日期：2020-01-01 00:00:00

abstract：:Viruses cause asthmatic exacerbations in schoolchildren. We tested the hypothesis that children who wheezed with viral respiratory tract infections secrete higher levels of the type 1 cytokine interferon-gamma (IFN-gamma) in the peripheral circulation than children who had never wheezed. Blood was taken from 13 childr...

journal_title：Allergy

authors： Leech SC,Price JF,Holmes BJ,Kemeny DM

更新日期：2000-01-01 00:00:00