Breast milk fatty acid composition has a long-term effect on the risk of asthma, eczema, and sensitization.

abstract：BACKGROUND:The contribution of B-cell subsets and T-B cell interaction to the pathogenesis of allergic rhinitis (AR) and mechanisms of allergen immunotherapy (AIT) remain poorly understood. This study aimed to outline circulating B-cell signature, the underlying mechanism, and its association with clinical response to ...

journal_title：Allergy

authors： Yao Y,Wang N,Chen CL,Pan L,Wang ZC,Yunis J,Chen ZA,Zhang Y,Hu ST,Xu XY,Zhu RF,Yu D,Liu Z

更新日期：2020-10-01 00:00:00

abstract：:The distribution of total serum-IgE and factors of importance for the level of IgE was studied in a random sample of 508 children and adolescents, aged 7-16 years, from Copenhagen. A detailed history about asthma, rhinitis, dermatitis and urticaria was obtained, and a physical examination, skin prick test with 9 commo...

journal_title：Allergy

authors： Backer V,Ulrik CS,Wendelboe D,Bach-Mortensen N,Hansen KK,Laursen EM,Dirksen A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be defined. Established animal models assessing the role(s) of eosinophils as contributors and/or causative agents of disease have relied on congenitally deficient mice w...

journal_title：Allergy

authors： Jacobsen EA,Lesuer WE,Willetts L,Zellner KR,Mazzolini K,Antonios N,Beck B,Protheroe C,Ochkur SI,Colbert D,Lacy P,Moqbel R,Appleton J,Lee NA,Lee JJ

更新日期：2014-03-01 00:00:00

abstract：:We challenged in a double-blind manner 46 pollen-allergic patients with 30 g of honey and another 32 patients with a placebo (30 g of syrup). Minor, mostly subjective, symptoms were seen in or reported by 26% of those challenged with honey and 41% of those challenged with placebo. In no case could the symptoms with ce...

journal_title：Allergy

authors： Kiistala R,Hannuksela M,Mäkinen-Kiljunen S,Niinimäki A,Haahtela T

更新日期：1995-10-01 00:00:00

abstract：:Women's work has traditionally been considered less hazardous to health in comparison with men's work. The increased women's participation in the workforce has led to an increased attention to women's working conditions. Women and men are unequally represented in individual professions or sectors (horizontal segregati...

journal_title：Allergy

authors： Moscato G,Apfelbacher C,Brockow K,Eberle C,Genuneit J,Mortz CG,Quecchia C,Quirce S,Siracusa A,Tarlo SM,van Kampen V,Walusiak-Skorupa J,Raulf M

更新日期：2020-11-01 00:00:00

abstract：:Quantiative immunoelectrophoresis used for the analysis of a dialysed, centrifuged and freeze-dried extract from cow hair and dander revealed 17 antigens. Five of these were identified as serum proteins. Partial identity to antigens of serum and extract from hair and dander of goat, sheep, swine, horse, dog, cat and g...

journal_title：Allergy

authors： Prahl P,Weeke B,Løwenstein H

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific in...

journal_title：Allergy

authors： Pignatti P,Perfetti L,Galdi E,Pozzi V,Bossi A,Biale C,Moscato G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Hippo-Yes-associated protein (YAP) pathway plays an important role in epithelial cell proliferation and development. However, its possible role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains unknown. We aim to investigate it on nasal epithelial proliferation and remodeling in CRSwNP. METHODS:T...

journal_title：Allergy

authors： Deng H,Sun Y,Wang W,Li M,Yuan T,Kong W,Huang X,Long Z,Chen Z,Wang D,Yang Q

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Exposure to environmental endocrine-disrupting chemicals (EDCs) is associated with allergy, chronic inflammation, and immunodeficiency. Phthalates, the common EDCs used in plastic industry, may act as adjuvants to disrupt immune system and enhance allergy. Plasmacytoid DCs (pDCs) are predominant cells secret...

journal_title：Allergy

authors： Kuo CH,Hsieh CC,Kuo HF,Huang MY,Yang SN,Chen LC,Huang SK,Hung CH

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire. METHODS:To validate questions used in a country-wide study among university students aged 18-25 year...

journal_title：Allergy

authors： Kilpeläinen M,Terho EO,Helenius H,Koskenvuo M

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:While immediate-type clinical reactions to food can quite easily be identified by history or measurement of specific IgE in combination with positive oral food challenges, the evaluation of food allergy in the absence of immediate clinical reactions still presents diagnostic difficulties--particularly in chi...

journal_title：Allergy

authors： Niggemann B,Reibel S,Wahn U

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Aluminium (ALUM) is used as experimental and clinical adjuvant for parenteral vaccine formulation. It is also contained in anti-acid drugs like sucralfate (SUC). These anti-acids have been shown to cause sensitization to food proteins via elevation of the gastric pH. The aim of this study was to assess the o...

journal_title：Allergy

authors： Brunner R,Wallmann J,Szalai K,Karagiannis P,Altmeppen H,Riemer AB,Jensen-Jarolim E,Pali-Schöll I

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:In addition to the dysregulation of arachidonic acid metabolism in aspirin-intolerant asthma (AIA), aspirin acetylsalicylic acid (ASA) exerts effects on inflammation and immunity; however, many of these effects are unknown. OBJECTIVE:The aim of the study was to evaluate the methylation status of whole genom...

journal_title：Allergy

authors： Cheong HS,Park SM,Kim MO,Park JS,Lee JY,Byun JY,Park BL,Shin HD,Park CS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The worldwide increasing incidence of allergic diseases requires the development of new, efficient vaccination strategies, the only curative treatment with a long-lasting effect. Current allergen-specific immunotherapy protocols suffer from limited efficacy and a long treatment time. METHODS:We engineered m...

journal_title：Allergy

authors： Crameri R,Flückiger S,Daigle I,Kündig T,Rhyner C

更新日期：2007-02-01 00:00:00

abstract：:Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H(1)-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only mediator involved in the inflammatory cascade. Th...

journal_title：Allergy

authors： Mullol J,Bousquet J,Bachert C,Canonica WG,Gimenez-Arnau A,Kowalski ML,Martí-Guadaño E,Maurer M,Picado C,Scadding G,Van Cauwenberge P

更新日期：2008-04-01 00:00:00

abstract：:Inbred guinea pigs selected for high (IMM/S) respectively low (IMM/R) responsiveness to ovalbumin (OA) as measured by induced respiratory anaphylaxis, were investigated for atopic immune responses of their conjunctival mucosa. IMM/S animals sensitized either by inhalation of OA, or by instillation of antigen into the ...

journal_title：Allergy

authors： Lundberg L,Bertelsen C,Zavaro A,Samra Z,Sompolinsky D

更新日期：1987-05-01 00:00:00

abstract：:House-dust mites are a major source of allergens. Beds are often heavily infested. It is conceivable that, during the winter period in temperate climates, the ambient indoor air is too dry for their survival, but that mites can still survive in beds where the humidity is raised when the bed is occupied. To investigate...

journal_title：Allergy

authors： de Boer R,Kuller K

更新日期：1997-03-01 00:00:00

abstract：:We observed two cases of maculopapular eruption occurring 12-72 h after the administration of aminocaproic acid (ACA). Patch tests performed with ACA were positive. Clinical and allergologic patterns suggest the type IV mechanism of hypersensitivity. We present what we believe are the first two cases described of hype...

journal_title：Allergy

authors： González Gutiérrez ML,Esteban López MI,Ruíz Ruíz MD

更新日期：1995-09-01 00:00:00

abstract：:B cells are essentially described for their capacity to produce antibodies ensuring anti-infectious immunity or deleterious responses in the case of autoimmunity or allergy. However, abundant data described their ability to restrain inflammation by diverse mechanisms. In allergy, some regulatory B-cell subsets produci...

journal_title：Allergy

authors： Braza F,Chesne J,Castagnet S,Magnan A,Brouard S

更新日期：2014-11-01 00:00:00

abstract：:Species of the Cupressaceae family are a worldwide cause of respiratory allergies. We used monoclonal antibodies (mAbs) to investigate the presence and the nature of cross-reacting epitopes shared by various components within Cupressus arizonica pollen extract (CaE) or by CaE and pollen extract from C. sempervirens (C...

journal_title：Allergy

authors： Barletta B,Tinghino R,Corinti S,Afferni C,Iacovacci P,Mari A,Pini C,Di Felice G

更新日期：1998-06-01 00:00:00

abstract：:Arachidonic acid metabolism represents an important source of mediators with ambivalent actions. Among these, lipoxins (LXs) are the first agents identified and recognized as anti-inflammatory endogenous lipid mediators, which are involved in the resolution of inflammation and are present in the airways of asthmatic p...

journal_title：Allergy

authors： Bonnans C,Chanez P,Chavis C

更新日期：2004-10-01 00:00:00

abstract：:The xenotransplantation research is driven by the increasing gap between the number of patients with end-stage organ failure on waiting lists for transplantation and the supply of allografts. The lack of success in developing suitable artificial organs for permanent treatment of organ failure has further strengthened ...

journal_title：Allergy

authors： Mollnes TE,Fiane AE

更新日期：2002-01-01 00:00:00

abstract：:We investigated the proliferative response of lymphocytes from mite-sensitive patients (RAST D.far greater than 3.5 PRU/ml) in the presence of the major allergen Der.f.I purified from Dermatophagoides farinae. Comparative studies were carried out with peripheral blood mononuclear cells from non-atopic donors (RAST = 0...

journal_title：Allergy

authors： Cavaillon JM,Fitting C,Guinnepain MT,Rassemont R,David B

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Immunotherapy with Hymenoptera venoms is highly effective but causes allergic side-effects frequently, especially when honeybee venom is used. Therefore, our objective was to investigate the effect of pretreatment with the antihistamine fexofenadine on the incidence of allergic side-effects during ultrarush ...

journal_title：Allergy

authors： Reimers A,Hari Y,Müller U

更新日期：2000-05-01 00:00:00

abstract：:The diagnosis of allergic reactions in clinical practice is based on both clinical history and the determination of specific immunoglobulin E (IgE), either in the serum or on skin mast cells. However, for various reasons, identification of the causative factors is not possible in all the cases. Moreover, not all aller...

journal_title：Allergy

authors： Demoly P,Lebel B,Arnoux B

更新日期：2003-07-01 00:00:00

abstract：:A shared approach to decision-making framework has been suggested for chronic disease management especially where multiple treatment options exist. Shared decision-making (SDM) requires that both physician and patients are actively engaged in the decision-making process, including information exchange; expressing trea...

journal_title：Allergy

authors： Pollard S,Bansback N,FitzGerld JM,Bryan S

更新日期：2017-05-01 00:00:00

abstract：:In order to establish reference values for total serum IgE in an adult non-atopic population, 175 individuals, 17-85 years of age, were investigated. The usefulness of a sensitive method (PRIST) for serum IgE determinations in discriminating atopy from non-atopic conditions in allergological routine diagnosis was eluc...

journal_title：Allergy

authors： Zetterström O,Johansson SG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Allergy diagnosis by determination of allergen-specific IgE is complicated by clinically irrelevant IgE, of which the most prominent example is IgE against cross-reactive carbohydrate determinants (CCDs) that occur on allergens from plants and insects. Therefore, CCDs cause numerous false-positive results. I...

journal_title：Allergy

authors： Holzweber F,Svehla E,Fellner W,Dalik T,Stubler S,Hemmer W,Altmann F

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:A previous investigation of all 10 TLR genes for associations with allergic rhinitis (AR) detected a number of significant SNPs in the TLR8 locus. The associations indicated that an accumulation of rare variants could explain the signal. This study therefore searches for rare variants in the TLR8 region and ...

journal_title：Allergy

authors： Henmyr V,Lind-Halldén C,Carlberg D,Halldén C,Melén E,Wickman M,Bergström A,Säll T,Cardell LO

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Mustard IgE-mediated allergy is supposed to be a rare cause of food allergy, and its clinical features and cross-reactivities have not been fully elucidated. METHODS:A prospective study was carried out, recruiting mustard allergic patients, and paired control subjects. A clinical questionnaire was administe...

journal_title：Allergy

authors： Figueroa J,Blanco C,Dumpiérrez AG,Almeida L,Ortega N,Castillo R,Navarro L,Pérez E,Gallego MD,Carrillo T

更新日期：2005-01-01 00:00:00