Abstract:
:We investigated the proliferative response of lymphocytes from mite-sensitive patients (RAST D.far greater than 3.5 PRU/ml) in the presence of the major allergen Der.f.I purified from Dermatophagoides farinae. Comparative studies were carried out with peripheral blood mononuclear cells from non-atopic donors (RAST = 0), and from patients undergoing hyposensitization treatment (5 to 24 months). According to Student's t-test, there was no significant difference in the Der.f.I-induced proliferation of peripheral blood mononuclear cells from normal donors, untreated atopic patients and hyposensitized patients. In conclusion, it was impossible to discriminate between normal donors, atopic patients and hyposensitized patients with regard to their circulating lymphocyte responses to the purified major allergen Der.f.I.
journal_name
Allergyjournal_title
Allergyauthors
Cavaillon JM,Fitting C,Guinnepain MT,Rassemont R,David Bdoi
10.1111/j.1398-9995.1988.tb00409.xsubject
Has Abstractpub_date
1988-02-01 00:00:00pages
146-51issue
2eissn
0105-4538issn
1398-9995journal_volume
43pub_type
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