Abstract:
:The presence of indoor allergens in Finnish homes was studied for the first time. Dust samples (n = 30) were collected by vacuuming a 1 m2 area from a living-room carpet in 30 apartments divided into three groups: homes with cats (n = 10), homes with dogs (n = 10), and homes without pets (n = 10). The levels of major cat (Fel d 1), dog (Can f 1), and house-dust-mite (Der p 1) allergens were analyzed by two-site ELISA methods. Der p 1 levels were below the detection limit in all dust samples. In the homes with cats or dogs, Fel 1 d and Can f 1 levels ranged from 147 to 2800 micrograms/g (geometric mean 296 micrograms/g), respectively, 567 micrograms/g), and from 86 to 1400 micrograms/g (geometric mean 296 micrograms/g), respectively, being slightly higher than those reported elsewhere. Low allergen levels, mainly below 3 micrograms/g were also detected in the homes without pets, indicating the transfer of allergens from place to place. However, in 25% of these samples, allergen levels exceeded the proposed threshold levels for cat or dog sensitization. The presence of pets was the most significant factor affecting cat and dog allergen levels in the house dust, and other factors, such as the amount of dust collected, residential time, and cleaning habits, had no or only a weak effect on allergen levels.
journal_name
Allergyjournal_title
Allergyauthors
Raunio P,Pasanen AL,Reiman M,Virtanen Tdoi
10.1111/j.1398-9995.1998.tb03870.xsubject
Has Abstractpub_date
1998-02-01 00:00:00pages
195-9issue
2eissn
0105-4538issn
1398-9995journal_volume
53pub_type
杂志文章相关文献
ALLERGY文献大全abstract:BACKGROUND:Recent studies have yielded heterogeneous results regarding the relationship between vitamin D and atopic conditions. The aim of this study was to investigate the association between serum vitamin D level and the prevalence of eczema in German children and adolescents. METHODS:Data were drawn for children a...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.12167
更新日期:2013-07-01 00:00:00
abstract:RATIONALE:The European Position Paper on Sinusitis (EPOS) guidelines provide composite criteria to evaluate chronic rhinosinusitis (CRS) control, taking into consideration the severity of patients' symptoms, aspect of nasal mucosa and medical intake as parameters of CRS control. OBJECTIVES:To study the degree of CRS c...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.12983
更新日期:2017-02-01 00:00:00
abstract::We describe eight patients suffering from Mercurochrome allergy. Patch and prick tests were carried out with the following organic and inorganic mercury compounds: thimerosal, Mercurochrome, phenylmercuric acetate, phenylmercuric nitrate, metallic mercury, and mercuric chloride, and with sodium fluorescein. Two patien...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1997.tb00190.x
更新日期:1997-11-01 00:00:00
abstract::In a double blind study, alcohol/onion extract (5% ethanol) was injected simultaneously with 20 IU and 200 IU rabbit anti-human-IgE intradermally in 12 adult volunteers (6 atopics, 6 non-atopics). Diameters of wheals and flares were measured 10 min after and compared with control sites challenged with 20 IU and 200 IU...
journal_title:Allergy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1398-9995.1984.tb01932.x
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Previous observational studies have implied breastmilk fatty acid composition may play a role in the development of atopic eczema or atopic sensitization in breastfed infants and toddlers. However, studies investigating associations with wheeze and asthma in later childhood are scarce and did not account for...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.13161
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.14258
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:In a previous controlled study we demonstrated that preseasonal grass pollen immunotherapy for three years was effective in children. In the current study we examined the same group of patients to see if there is still a benefit six years after discontinuation of treatment. METHODS:Thirteen of 14 patients w...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1034/j.1398-9995.2002.1o3264.x
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains unclear. METHODS:FLG mutations R501X, 2282del4 and R2447X were genotyped in the Prevention and Incidence of Asthma and Mite Allergy birth cohort (n = 934) to evalu...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2009.02080.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The nasal allergen challenge (NAC) is a useful tool for the diagnosis of allergic rhinitis (AR) and local allergic rhinitis (LAR) and might serve to design and monitor allergen immunotherapy. Nevertheless, data about its safety and reproducibility are scarce. OBJECTIVE:To investigate the safety and reproduc...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.13728
更新日期:2019-06-01 00:00:00
abstract::The atopy-predictive value of cord blood (CB) cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) in mononuclear leukocytes (MN) was studied prospectively in 57 neonates. Reliable determination of cAMP-PDE was achieved in only 20 CB samples. The levels tended to be higher in infants developing signs of atopy u...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1994.tb00141.x
更新日期:1994-09-01 00:00:00
abstract::The red cell-linked antigen-antiglobulin reaction (RCLAAR) with stearoyldextran-coated erythrocytes was used to characterize the immunoglobulin (Ig) classes and IgG subclasses of dextran reactive antibodies (DRA) in 27 dextran reactors (DR) and 96 on reactors (DNR). High titres of dextran reactive IgG were regularly f...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1982.tb02331.x
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:A favorable outcome of anaphylaxis depends on the rapidity of adequate initial management and epinephrine injection. However, few data on the management of anaphylactic reactions are available. The aim of this study was to investigate the management and awareness of anaphylaxis to foods by mean of an Interne...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1034/j.1398-9995.2001.056006540.x
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Undernotification is well recognized as a key challenge to the study of anaphylaxis mortality, but it is seldom mentioned that one of its reasons is the difficult coding of the condition under the tenth revision of the international classification of diseases (ICD-10), given that there are no anaphylaxis-spe...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2012.02829.x
更新日期:2012-06-01 00:00:00
abstract::Although H1 antihistamine compounds (H1) are highly effective in the treatment of allergic rhinitis (AR), their role in the treatment of asthma is still controversial. Because a strong association between AR and bronchial hyperresponsiveness (BHR) has been reported, this study was designed to assess the effect of a ne...
journal_title:Allergy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1398-9995.2001.00629.x
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:There are large differences in the prevalence of atopic disease between urban and rural areas of developing countries, without good explanation. Diet has been associated with atopic disease, but studies of specific nutrients are contradictory, cross-sectional studies often being unsupported by trials. We inv...
journal_title:Allergy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1398-9995.2008.01627.x
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The genetic determinants of food allergy have not been systematically reviewed. We therefore systematically reviewed the literature on the genetic basis of food allergy, identifying areas for further investigation. METHODS:We searched three electronic databases (MEDLINE, EMBASE and PubMed) on 9 January 2018...
journal_title:Allergy
pub_type: 杂志文章,meta分析
doi:10.1111/all.13767
更新日期:2019-09-01 00:00:00
abstract::The present study was designed to investigate the effects of immunotherapy (IT) with an extract of Dermatophagoides pteronyssinus (Alergo-Merck Depot) during a 27-month period in patients with allergic asthma to house-dust mites. We included 11 patients (mean age 18 years) treated with a combination of IT and inhaled ...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1996.tb04599.x
更新日期:1996-04-01 00:00:00
abstract::Various biological assays are used for qualitative and quantitative measurements of interleukin 1 (IL-1) in supernatants from cell cultures. The purpose of the present study was to compare the specificity and variability of three cellular IL-1 bioassays: the PHA co-stimulatory human T lymphocyte proliferation assay, t...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1991.tb00544.x
更新日期:1991-01-01 00:00:00
abstract::Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rh...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/all.12686
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Two-flow cytometry methods for quantification of degranulated basophil after allergen-specific activation were discussed. The methods are discerned by used membrane receptors--FcepsilonRI or IL-3Ralpha Our goal was to evaluate the diagnostic potential of the methods and to correlate them to allergen-specific...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2006.01087.x
更新日期:2006-09-01 00:00:00
abstract::We developed an antigen- and isotype-specific ELISA for the rapid detection of native serum immune complexes (IC). It is a sandwich assay, in which a solid phase antigen-specific capture antibody selectively binds the antigen-specific IC via the antigen. The isotype of the bound IC is then identified using an enzyme-l...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1988.tb01626.x
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND:Artemisia annua is an important autumnal pollen allergen for seasonal allergic rhinitis (SAR) in northern China. To date, no study has investigated allergen immunotherapy with A annua. We aimed to investigate the efficacy and mechanisms underlying A annua-sublingual immunotherapy (SLIT). METHODS:This was a ...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.14218
更新日期:2020-08-01 00:00:00
abstract::Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes, thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to asthma, allergies, and allied diseases. Prostaglandins and leukotrienes are the most studied eicosanoids and established inducers of air...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/all.14295
更新日期:2021-01-01 00:00:00
abstract::Standardized bronchial allergen provocation with the same individual allergen dose was performed 3-9 times in 20 symptomless adult asthmatic patients at intervals of 1 week or more during 1/2-22 months in order to study variations in bronchial response. The immediate type reaction was recorded by monitoring FEV1, FVC,...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.1980.tb01777.x
更新日期:1980-06-01 00:00:00
abstract::Endocrine disrupters (EDs) are environmental pollutants of industrial or agricultural origin (e.g. herbicides, fungicides, insecticides, industrial chemicals) that may influence health of wildlife and human. Endocrine-disrupting effect is obtained by mimicking the action of the steroid hormones and has been associated...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2006.01135.x
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Intradermal skin testing of the clinically important antibiotics ciprofloxacin, clarithromycin, and rifampicin in the case of suspected allergies to antibiotics is poorly standardized. For clinical practice, standardized procedures and protocols are desired. METHODS:Fifteen healthy volunteers were tested wi...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2012.02807.x
更新日期:2012-05-01 00:00:00
abstract::Basophils are evolutionarily conserved in many animal species, in spite of the fact that they account for <1% of peripheral blood leukocyte. This suggests that basophils have an indispensable and nonredundant role in vivo, even though they show some phenotypic similarity with tissue-resident mast cells. However, their...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2011.02613.x
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Mould-attributed symptoms have included features which overlap with unexplained syndromes such as sick building syndrome. OBJECTIVES:We describe questionnaire and chart review findings in patients following exposure to moulds which include Stachybotrys and compare responses with two control groups. METHODS...
journal_title:Allergy
pub_type: 杂志文章
doi:10.1111/j.1398-9995.2009.02157.x
更新日期:2010-02-01 00:00:00
abstract::Histamine is a key mediator in the development of allergy symptoms, and oral H(1)-antihistamines are among the most widely used treatments for symptomatic relief in conditions such as allergic rhinitis and chronic urticaria. Ebastine is a second-generation antihistamine which has been shown to be an effective treatmen...
journal_title:Allergy
pub_type: 杂志文章,评审
doi:10.1111/j.1398-9995.2008.01897.x
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if standard doses are ineffecti...
journal_title:Allergy
pub_type: 杂志文章,随机对照试验
doi:10.1111/all.12171
更新日期:2013-07-01 00:00:00