Effects of immunotherapy on symptoms, PEFR, spirometry, and airway responsiveness in patients with allergic asthma to house-dust mites (D. pteronyssinus) on inhaled steroid therapy.

abstract：BACKGROUND:Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. Studies with pollen allergen immunotherapy are limited to observational studies. The aim of this study was to evaluate the clinical efficacy and safety of Phleum pratense subcutaneous imm...

journal_title：Allergy

authors： Rondón C,Blanca-López N,Campo P,Mayorga C,Jurado-Escobar R,Torres MJ,Canto G,Blanca M

更新日期：2018-04-01 00:00:00

abstract：:The possible dependence of the dual cutaneous reaction (DCR) on activation of the complement and coagulation systems was further elucidated. Heterologous whole anti-human IgE was injected intradermally (i.d.) on the volar aspect of the forearms of 17 drug-free healthy volunteers and venous samples for the selected lab...

journal_title：Allergy

authors： Grönneberg R

更新日期：1985-11-01 00:00:00

abstract：:Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bake...

journal_title：Allergy

authors： Revsbech P,Dueholm M

更新日期：1990-04-01 00:00:00

abstract：:Food allergies have become a significant heath burden as prevalence continues to rise, affecting 6%-13% of the global population. In the absence of drugs approved by regulatory agencies, the current standard of care remains avoidance of allergenic foods and management of acute allergic reactions with antihistamines an...

journal_title：Allergy

authors： Sampath V,Sindher SB,Alvarez Pinzon AM,Nadeau KC

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Innate immune response by a viral pathogen-associated molecular pattern dsRNA modulates the subsequent development of adaptive immune responses. Although virus-associated asthma is characterized by noneosinophilic inflammation, the role of Th17 cell response in the development of virus-associated asthma is s...

journal_title：Allergy

authors： Choi JP,Kim YS,Tae YM,Choi EJ,Hong BS,Jeon SG,Gho YS,Zhu Z,Kim YK

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The atopy patch test (APT) is an in vivo model to study the induction of eczema by inhalant allergens. This study was designed to compare two commonly used APT methods. METHODS:In the first method, the allergen is dissolved in aqueous solution, which is applied on tape-stripped skin. In the second method, t...

journal_title：Allergy

authors： Oldhoff JM,Bihari IC,Knol EF,Bruijnzeel-Koomen CA,de Bruin-Weller MS

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is common in Kuwait, a desert country, but the sensitizing allergens are uncertain. This study investigated the sensitizing allergens in Kuwaiti patients with extrinsic asthma. METHODS:A total of 553 asthmatics (male:female ratio: 1.4; mean age: 31.7 years [range 3-76 years]) and 112 matche...

journal_title：Allergy

authors： Ezeamuzie CI,Thomson MS,Al-Ali S,Dowaisan A,Khan M,Hijazi Z

更新日期：2000-02-01 00:00:00

abstract：:We measured the IgG subclass antibody levels to wheat flour in 42 bakers and 20 controls with an enzyme immunoassay. The levels of total IgG, IgG1 IgG2 and IgG4 antibodies were significantly higher in the bakers than in the unexposed controls. The presence of anti-wheat flour IgG subclass antibodies in the bakers was ...

journal_title：Allergy

authors： Tiikkainen U,Klockars M

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:IL-31 is a cytokine expressed by T cells following activation with cytokines or staphylococcal exotoxins. A major function of IL-31 in atopic dermatitis (AD) is the induction of pruritus in the skin via the IL-31 receptor on sensory nerve cells. However, the regulation of the IL-31 receptor and pro-inflammat...

journal_title：Allergy

authors： Kasraie S,Niebuhr M,Werfel T

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Food allergy in children can be life-threatening. Component-resolved diagnostics approach to food anaphylaxis is rarely assessed in children. The aim of the study was to identify the food allergen components as the triggers responsible for severe anaphylaxis, with regard to characteristics and associated ris...

journal_title：Allergy

authors： Blazowski L,Majak P,Kurzawa R,Kuna P,Jerzynska J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Genomewide association and epigenetic studies found a region within the RAD50 gene on chromosome 5q31 to be associated with total serum IgE levels and asthma. In mice, this region harbors a locus control region for nearby TH 2 cytokines, which is characterized by four Rad50 DNase I hypersensitive sites (RHS4...

journal_title：Allergy

authors： Schieck M,Sharma V,Michel S,Toncheva AA,Worth L,Potaczek DP,Genuneit J,Kretschmer A,Depner M,Dalphin JC,Riedler J,Frei R,Pekkanen J,Tost J,Kabesch M

更新日期：2014-09-01 00:00:00

abstract：:The scarce data published on mite sensitization and mite-allergen levels in Norway indicate that the mites may not be of the same importance in allergic disease in Norway as in countries such as the UK and the rest of Europe. The problem also involves the low allergen levels and small amounts of dust collected for all...

journal_title：Allergy

authors： Gaarder PI

更新日期：1998-01-01 00:00:00

abstract：:Six children and six adults were given a single dose of a sustained release theophylline preparation (Nuelin Retard) after an overnight fast and later after a standardized breakfast. Food significantly reduced the absorption rate of theophylline whereas the extent of absorption of theophylline was unaffected by food. ...

journal_title：Allergy

authors： Pedersen S,Moeller-Petersen J

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Omalizumab, a recombinant monoclonal anti-immunoglobulin E (IgE) antibody, shows proven efficacy in the treatment of allergic diseases. A little is known about the immunological pathways affected by the decrease of circulating free IgE during omalizumab treatment. AIM OF THE STUDY:To investigate the immunol...

journal_title：Allergy

authors： Hanf G,Brachmann I,Kleine-Tebbe J,Seybold J,Kunkel G,Suttorp N,Noga O

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Clinically effective allergen-specific immunotherapy correlates with decreased circulating allergen-specific IL-4+ T cells but increased IFN-gamma+ cells at sites of allergen challenge. Whether immunotherapy promotes trafficking of IFN-gamma+ T cells to peripheral tissues is unknown. As aeroallergen is admin...

journal_title：Allergy

authors： Gardner LM,Spyroglou L,O'Hehir RE,Rolland JM

更新日期：2004-12-01 00:00:00

abstract：:The estimation of exposure to molds and their products in the indoor environment, which may lead to the occurrence of allergies or respiratory complaints, by means of enumeration of viable parts is inadequate. Therefore, other methods must be developed. When grown under various circumstances (22 degrees C and 30 degre...

journal_title：Allergy

authors： Wijnands LM,Deisz WD,van Leusden FM

更新日期：2000-09-01 00:00:00

abstract：:Release of antigen E-125 I from the site of subcutaneous injection in male rats was delayed significantly when either of two alum-precipitated preparations containing 1.0-1.2 mg of Al/ml was administered rather than an aqueous preparation. The rates of 125I excretion were similarly influenced being statistically slowe...

journal_title：Allergy

authors： Leeling JL,Muni IA,Helms RJ,Johnson N Jr

更新日期：1979-10-01 00:00:00

abstract：:A two-site immunometric assay based on monoclonal antibodies (mAb) was developed for the measurement of a 20-kDa major allergen of cow. The sensitivity of this assay was (BDA20) 1 ng/ml. It was used to measure airborne allergen concentrations in 10 Finnish cowsheds. The mean concentration of the BDA20 measured at two ...

journal_title：Allergy

authors： Ylönen J,Virtanen T,Rytkönen M,Mäntyjärvi R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:It has been suggested that human breast milk oligosaccharides play a role in the development of the immune system in infants, and may consequently inhibit the onset of allergy. A specific prebiotic mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (GOS/FOS) has been shown...

journal_title：Allergy

authors： van Hoffen E,Ruiter B,Faber J,M'Rabet L,Knol EF,Stahl B,Arslanoglu S,Moro G,Boehm G,Garssen J

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence, importance, and the order of frequency of IgE-mediated food allergens among infants and young children in Israel. STUDY DESIGN AND PATIENTS:In a cross-sectional study, the prevalence of IgE-mediated food allergy was investigated in 9070 infants and young children (0-2 years) who ...

journal_title：Allergy

authors： Dalal I,Binson I,Reifen R,Amitai Z,Shohat T,Rahmani S,Levine A,Ballin A,Somekh E

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Mastocytosis is characterized by the accumulation of mast cells (MCs) associated with activating mutations of KIT. Tumor necrosis factor-related apoptosis-inducing ligand receptors (TRAIL-Rs) are preferentially expressed on neoplastic cells and induce the extrinsic apoptotic pathway. Recent studies reported ...

journal_title：Allergy

authors： Förster A,Grotha SP,Seeger JM,Rabenhorst A,Gehring M,Raap U,Létard S,Dubreuil P,Kashkar H,Walczak H,Roers A,Hartmann K

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Latex sensitivity is an increasing problem among health-care workers. Allergic responses are associated with changes in nitric oxide (NO) generation and the changes secondary to latex have not been described. METHODS:A total of 22 subjects comprising equal numbers of control volunteers and subjects with sel...

journal_title：Allergy

authors： Tan K,Bruce C,Birkhead A,Thomas PS

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Occupational allergy forms an attractive model to study the development of allergic responses, as in some occupations it has a high incidence and develops quickly. In a cohort of starting laboratory animal workers, we previously found 20% sensitization to animal allergens within 2 years. METHODS:We compared...

journal_title：Allergy

authors： Krop EJ,van de Pol MA,Lutter R,Heederik DJ,Aalberse RC,van der Zee JS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The prevalence of self-reported symptoms of allergic rhinitis is increasing in many countries, but the reasons for this trend are not well understood. Data from a 6-year follow-up study of a population sample of children and adolescents (n=408), aged 7-17 years at enrolment in 1986, were analyzed to investig...

journal_title：Allergy

authors： Ulrik CS,von Linstow ML,Backer V

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific in...

journal_title：Allergy

authors： Pignatti P,Perfetti L,Galdi E,Pozzi V,Bossi A,Biale C,Moscato G

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Several studies have shown that allergy to natural rubber latex is associated with cross-reactivity to certain foods such as tomato and potato. The objective was to investigate the clinical and immunologic differences between a group of patients with clinical allergy to tomato and latex and another which had...

journal_title：Allergy

authors： Reche M,Pascual CY,Vicente J,Caballero T,Martín-Muñoz F,Sanchez S,Martín-Esteban M

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:CD40 and OX40 Ligand (OX40L) are cell-surface molecules expressed on airway smooth muscle (ASM) that can enhance inflammatory cell activation and survival. The aim of this study was to examine the effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on ASM CD40 and OX40L expres...

journal_title：Allergy

authors： Krimmer DI,Loseli M,Hughes JM,Oliver BG,Moir LM,Hunt NH,Black JL,Burgess JK

更新日期：2009-07-01 00:00:00

abstract：:Anaphylaxis is a growing paediatric clinical emergency that is difficult to diagnose because a consensus definition was lacking until recently. Many European countries have no specific guidelines for anaphylaxis. This position paper prepared by the EAACI Taskforce on Anaphylaxis in Children aims to provide practical g...

journal_title：Allergy

authors： Muraro A,Roberts G,Clark A,Eigenmann PA,Halken S,Lack G,Moneret-Vautrin A,Niggemann B,Rancé F,EAACI Task Force on Anaphylaxis in Children.

更新日期：2007-08-01 00:00:00

abstract：:Quantitative determinations of the inflammatory mediators in nasal secretions were performed and correlated with the objective nasal symptoms within 1 h after nasal allergen challenge (NAC). Twenty-six patients with seasonal allergic rhinitis were enrolled outside the pollen season. All measurements were performed bef...

journal_title：Allergy

authors： Wang D,Smitz J,Waterschoot S,Clement P

更新日期：1997-02-01 00:00:00

abstract：:The protective effect of terfenadine on inflammatory processes following the early phase of conjunctival provocation tests by specific allergen was assessed in 24 patients suffering from seasonal allergic rhinoconjunctivitis, in a single-blind, randomized, placebo-controlled, parallel-group study. Patients were random...

journal_title：Allergy

authors： Ciprandi G,Buscaglia S,Iudice A,Canonica GW

更新日期：1992-08-01 00:00:00