Genome-wide methylation profile of nasal polyps: relation to aspirin hypersensitivity in asthmatics.

abstract：:Oral immunotherapy (IT) was evaluated in a pilot study in two centres in children aged 8-15 years with allergic rhinoconjunctivitis. High doses (up to 20 X 10(6) BU monthly) of a defined freeze-dried birch pollen extract administered in enteric-coated gelatine capsules were given either daily for seven consecutive day...

journal_title：Allergy

authors： Björkstén B,Möller C,Broberger U,Ahlstedt S,Dreborg S,Johansson SG,Juto P,Lanner A

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-9, an enzyme that contributes to inflammatory responses and subsequent tissue remodelling, has recently been suggested to be a good biomarker for monitoring disease activity in patients with chronic urticaria (CU). Here, we assessed whether total MMP-9 and/or active MMP-9 plasm...

journal_title：Allergy

authors： Altrichter S,Boodstein N,Maurer M

更新日期：2009-04-01 00:00:00

abstract：:An atopic girl experienced an anaphylactic reaction after eating cookies containing pecan nuts. Investigations revealed that she had developed IgE antibodies exclusively specific against allergenic determinants present in aged or heated pecan nuts, but not in fresh pecans. These neoallergenic determinants were located...

journal_title：Allergy

authors： Malanin K,Lundberg M,Johansson SG

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:There is theoretical evidence that specific airway conductance (SGaw) could be more reliable than forced expiratory volume in 1 s (FEV1) for assessing changes in airway calibre. We investigated the changes in FEV1 and SGaw when assessing bronchial responses to occupational agents. METHODS:SGaw and FEV1 were...

journal_title：Allergy

authors： Larbanois A,Delwiche JP,Jamart J,Vandenplas O

更新日期：2003-12-01 00:00:00

abstract：:House dust mite D. farinae and Der f II-specific IgG and IgG subclass responses were evaluated in 32 adults with perennial rhinitis undergoing immunotherapy for 1 year by means of IgG-RAST and ELISA. The ELISA method, which is based on subclass-specific monoclonal antibodies, could detect 0.5-1.5 ng/ml of specific ant...

journal_title：Allergy

authors： Einarsson R,Dreborg S,Hammarström L,Löfkvist T,Smith CI,Svensson G

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has been identified as the major birch pollen allergen. However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 and other components of the birch pollen extract, remain incompletely understoo...

journal_title：Allergy

authors： Soh WT,Aglas L,Mueller GA,Gilles S,Weiss R,Scheiblhofer S,Huber S,Scheidt T,Thompson PM,Briza P,London RE,Traidl-Hoffmann C,Cabrele C,Brandstetter H,Ferreira F

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34(+) hemopoietic progenitor cells (HPC). Depending on the stage of maturation and the environment, MC variably express differentiation- and activation-linked antigens. Little is known, however, about the ...

journal_title：Allergy

authors： Schernthaner GH,Hauswirth AW,Baghestanian M,Agis H,Ghannadan M,Worda C,Krauth MT,Printz D,Fritsch G,Sperr WR,Valent P

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:We evaluated the ENEA System, a fully automated instrument for the measurement of specific IgE antibodies. The instrument dispenses sera and reagents, incubates, washes, and reads and prints results automatically. The "core" of the instrument is the reactive unit called ACE (Allergy Chamber Enzymatic), which...

journal_title：Allergy

authors： Plebani M,Faggian D,Borghesan F

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Exposure and contact with bee moth (Galleria mellonella) larvae (Gm) can cause an allergic reaction both in anglers and breeders. We described the case of an amateur fisherman who experienced an allergic reaction using Gm but not using heat-treated Gm (h-Gm) (mummies). The aim of this study was to demonstrat...

journal_title：Allergy

authors： Villalta D,Martelli P,Mistrello G,Roncarolo D,Zanoni D

更新日期：2004-09-01 00:00:00

abstract：:Using monoclonal anti-human IgE antibodies recognizing the D epsilon 1 or D epsilon 2 epitope, we have developed a sandwich radioimmunoassay (RIA) to determine IgE in human cell cultures. With the help of this assay, various methods of measuring an actual de novo IgE synthesis were compared. It was necessary to subtra...

journal_title：Allergy

authors： Knutti-Müller JM,Stadler BM,Magnusson CM,de Weck L

更新日期：1986-08-01 00:00:00

abstract：:In a double-blind controlled trial 41 hospitalized adults with severe, perennial asthma of unknown aetiology were allocated to either an antigen-free elemental diet (Vivasorb) or control diet, i.e. blended ordinary hospital food, for 2 weeks. At the time of entry into the trial all patients were in an active but stabl...

journal_title：Allergy

authors： Høj L,Osterballe O,Bundgaard A,Weeke B,Weiss M

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The mechanisms of late asthmatic reactions provoked in atopic asthmatics by allergen-derived T-cell peptide epitopes remain unclear. Previous studies showed no changes in airway eosinophils or mast cell products after peptide challenge. In the present study our aim was to measure calcitonin gene-related pept...

journal_title：Allergy

authors： Kay AB,Ali FR,Heaney LG,Benyahia F,Soh CP,Renz H,Lee TH,Larché M

更新日期：2007-05-01 00:00:00

abstract：:The scarce data published on mite sensitization and mite-allergen levels in Norway indicate that the mites may not be of the same importance in allergic disease in Norway as in countries such as the UK and the rest of Europe. The problem also involves the low allergen levels and small amounts of dust collected for all...

journal_title：Allergy

authors： Gaarder PI

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Chitotriosidase (chitinase 1, Chit1), a major true chitinase in humans, is induced in childhood asthma and has been implicated in the pathogenesis of a variety of inflammatory and tissue remodeling responses. However, the role and the mechanisms that underlie these contributions to the diseases have not been...

journal_title：Allergy

authors： Hong JY,Kim M,Sol IS,Kim KW,Lee CM,Elias JA,Sohn MH,Lee CG

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Adolescents have the highest risk for food allergy-related fatalities. Our main aim was to investigate the level of risk in everyday social situations as perceived by adolescents/young adults with peanut allergy, their families, and their friends. METHODS:The web-based 'Colours Of Risks' (COR) questionnaire...

journal_title：Allergy

authors： Stensgaard A,DunnGalvin A,Nielsen D,Munch M,Bindslev-Jensen C

更新日期：2017-07-01 00:00:00

abstract：:IgG-binding to the surface of Langerhans cells (LC) is a feature of primary Sjögren's syndrome and might be associated with qualitative and quantitative defects in LC. Fifteen patients with primary Sjögren's syndrome and 15 healthy controls had a punch biopsy performed from clinically unaffected skin. LC were enumerat...

journal_title：Allergy

authors： Oxholm P,Oxholm A,Manthorpe R

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:The reasons for the rise in asthma and allergies remain unclear. To identify risk or protective factors, it is essential to carry out longitudinal epidemiological studies, preferably birth cohort studies. In Europe, several birth cohort studies on asthma and atopic diseases have been initiated over the last ...

journal_title：Allergy

authors： Keil T,Kulig M,Simpson A,Custovic A,Wickman M,Kull I,Lødrup Carlsen KC,Carlsen KH,Smit HA,Wijga AH,Schmid S,Berg A,Bollrath C,Eller E,Bindslev-Jensen C,Halken S,Høst A,Heinrich J,Porta D,Forastiere F,Brunekreef B

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is a chronic disease characterized by inflammation, obstruction, and hyperresponsiveness of the airways. There is currently no curative therapy for asthma. Type 2 helper T cell response plays a critical role in the pathogenesis of the disease. Protein S is a glycoprotein endowed with anticoa...

journal_title：Allergy

authors： Asayama K,Kobayashi T,D'Alessandro-Gabazza CN,Toda M,Yasuma T,Fujimoto H,Okano T,Saiki H,Takeshita A,Fujiwara K,Fridman D'Alessandro V,Nishihama K,Totoki T,Inoue R,Takei Y,Gabazza EC

更新日期：2020-09-01 00:00:00

abstract：:Food allergies have become a significant heath burden as prevalence continues to rise, affecting 6%-13% of the global population. In the absence of drugs approved by regulatory agencies, the current standard of care remains avoidance of allergenic foods and management of acute allergic reactions with antihistamines an...

journal_title：Allergy

authors： Sampath V,Sindher SB,Alvarez Pinzon AM,Nadeau KC

更新日期：2020-06-01 00:00:00

abstract：:Although copper sulfate can cause systemic contact dermatitis, few such cases have been recorded among copper-releasing IUD users. Reported in this paper is a case of endometritis and urticaria-angioedema syndrome in a 32-year-old user of a copper IUD. Widespread urticaria, as well as angioedema of the eyelids and t...

journal_title：Allergy

authors： Purello D'Ambrosio F,Ricciardi L,Isola S,Gangemi S,Cilia M,Levanti C,Marcazzò A

更新日期：1996-09-01 00:00:00

abstract：:The clinical scoring systems of atopic dermatitis were analysed and compared. Some biological parameters that can correlate with the clinical score were also reviewed. After the definition of the disease based on validated clinical criteria, the second necessity was the availability of reliable severity scores to allo...

journal_title：Allergy

authors： Gelmetti C,Colonna C

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Polcalcins are pollen-specific allergens with two EF-hand calcium-binding sites that exhibit strong cross-reactivity. Our objective was to isolate and express the cDNA coding of the EF-hand calcium-binding allergen from lilac pollen and to study cross-reactivity with other polcalcins from related and nonrela...

journal_title：Allergy

authors： Ledesma A,Barderas R,Westritschnig K,Quiralte J,Pascual CY,Valenta R,Villalba M,Rodríguez R

更新日期：2006-04-01 00:00:00

abstract：:This is a description of the Study of Asthma, Genes and the Environment (SAGE), a novel birth cohort created from provincial healthcare administrative records. It is a general population-based cohort, composed of children at high and low risk for asthma, living in urban and rural environments in Manitoba, Canada. The ...

journal_title：Allergy

authors： Kozyrskyj AL,HayGlass KT,Sandford AJ,Paré PD,Chan-Yeung M,Becker AB

更新日期：2009-08-01 00:00:00

abstract：:Histamine is a key mediator in the development of allergy symptoms, and oral H(1)-antihistamines are among the most widely used treatments for symptomatic relief in conditions such as allergic rhinitis and chronic urticaria. Ebastine is a second-generation antihistamine which has been shown to be an effective treatmen...

journal_title：Allergy

authors： Sastre J

更新日期：2008-12-01 00:00:00

abstract：:Several studies have indicated that the incidence and prevalence of allergic diseases are increasing. Such data should not be regarded as mere statistical curiosities, but should be analysed to provide information on the factors contributing to allergy and its changing epidemiology. Extensive evidence has been accumul...

journal_title：Allergy

authors： Bonini S,Magrini L,Rotiroti G,Ronchetti MP,Onorati P

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Blomia tropicalis is an important mite species in the tropical and sub-tropical regions of the world. Blo t 5 is the major allergen with up to 70% sensitization rates in B. tropicalis allergic populations. METHODS:Mice were immunized intramuscularly with naked plasmid DNA encoding Blo t 5 gene with in vivo ...

journal_title：Allergy

authors： Yi FC,Lee BW,Cheong N,Chua KY

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Systemic allergic reactions are a risk for allergen immunotherapy that utilizes intact allergen preparations. We evaluated the safety, efficacy and immune mechanisms of short-course treatment with adjuvant-free Lolium perenne peptides (LPP) following a 6-week dose-escalation protocol. METHODS:In a prospecti...

journal_title：Allergy

authors： Mösges R,Koch AF,Raskopf E,Singh J,Shah-Hosseini K,Astvatsatourov A,Hauswald B,Yarin Y,Corazza F,Haazen L,Pirotton S,Allekotte S,Zadoyan G,Legon T,Durham SR,Shamji MH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The aim of this paper was to investigate the role of SLPI in patients with allergic rhinitis. From this point of view, we also examined leukocyte elastase, alpha1-antitrypsin, and albumin. SLPI is an inhibitor of serine proteases such as leukocyte elastase, cathepsin G, and mast-cell chymase. Since chymase i...

journal_title：Allergy

authors： Westin U,Lundberg E,Wihl JA,Ohlsson K

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Hereditary angioedema (HAE), type I and II, is an autosomal dominant disease with deficiency of functional C1 inhibitor protein causing episodic swellings of skin, mucosa and viscera. HAE is a genetically heterogeneous disease with more than 200 different mutations in the SERPING1 gene. A genotype-phenotype ...

journal_title：Allergy

authors： Bygum A,Fagerberg CR,Ponard D,Monnier N,Lunardi J,Drouet C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:IgE-independent (pseudoallergic) reactions to food and food ingredients are common in a subgroup of adult patients with chronic urticaria, who have daily spontaneous occurrence of wheals. However, for children with chronic urticaria (duration longer than 6 weeks, no physical influence), no data on the import...

journal_title：Allergy

authors： Ehlers I,Niggemann B,Binder C,Zuberbier T

更新日期：1998-11-01 00:00:00