Cytodestructive mechanisms provoked by food antigens. I. Direct, allergic autocytotoxicity.

Abstract:

:In vitro challenge of peripheral white blood cells (WBC) from 62 food sensitive patients and 22 asymptomatic control individuals was performed using standardized extract of cow milk, corn and wheat. 81% of the patients reacted at least toward one food antigen, showing disintegration of WBC, as measured by trypan blue exclusion technique. The presented experimental condition of the direct binding between food antigen and cell wall membrane suggests that this phenomenon is multicellular in its origin. The interpretation of these studies is of distinct value in directing human food hypersensitivity research in the future.

journal_name

Allergy

journal_title

Allergy

authors

Podleski WK

doi

10.1111/j.1398-9995.1985.tb00211.x

subject

Has Abstract

pub_date

1985-04-01 00:00:00

pages

157-65

issue

3

eissn

0105-4538

issn

1398-9995

journal_volume

40

pub_type

杂志文章

相关文献

ALLERGY文献大全
  • Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of glucocorticoid treatment.

    abstract::We examined the effects of glucocorticosteroids (GCS) on antigen-induced bronchial anaphylactic reactions (BAR) in SD rats immunized with ovalbumin (OA) and alum. The animals were treated with vehicle, budesonide (BUD), dexamethasone (DEX), or hydrocortisone (HC) at various times before intravenous (i.v.) antigen chal...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1986.tb00302.x

    authors: Dahlbäck M,Bergstrand H,Brattsand R

    更新日期:1986-04-01 00:00:00

  • Alpine climate treatment of atopic dermatitis: a systematic review.

    abstract::Climate therapy has been used for decades in the treatment of atopic dermatitis (AD), but evidence of its effectiveness has not yet been assessed systematically. A systematic literature search in Medline, Embase, and the Cochrane library was performed to identify all original studies concerning alpine climate treatmen...

    journal_title:Allergy

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/all.12514

    authors: Fieten KB,Weststrate AC,van Zuuren EJ,Bruijnzeel-Koomen CA,Pasmans SG

    更新日期:2015-01-01 00:00:00

  • Bronchial and basophil reaction to polymyxin B in asthmatic patients.

    abstract::The hypothesis that increased reactivity to polymyxin B in asthmatic patients is not limited to the bronchi but also exists in basophils was investigated in 26 atopic asthmatic subjects. Quantification of basophil degranulation induced by polymyxin B was performed using a flow-cytometric method. Significant degranulat...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1985.tb04157.x

    authors: Górski P,Rozniecki J,Kuźmińska B,Grzegorczyk J

    更新日期:1985-01-01 00:00:00

  • Prolactin and contact sensitivity.

    abstract::Hypophysectomized (Hypo-X) rats did not develop contact dermatitis in response to dinitrochlorobenzene (DNCB). Syngeneic pituitary grafts placed under the kidney capsule or daily treatment with prolactin restored the DNCB-reactivity of Hypo-X animals. Combined treatment with other pituitary hormones was ineffective. T...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1981.tb01850.x

    authors: Nagy E,Berczi I

    更新日期:1981-08-01 00:00:00

  • Experimental allergic conjunctivitis in inbred guinea pig strains with high respectively low bronchial allergic reactivity.

    abstract::Inbred guinea pigs selected for high (IMM/S) respectively low (IMM/R) responsiveness to ovalbumin (OA) as measured by induced respiratory anaphylaxis, were investigated for atopic immune responses of their conjunctival mucosa. IMM/S animals sensitized either by inhalation of OA, or by instillation of antigen into the ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1987.tb02208.x

    authors: Lundberg L,Bertelsen C,Zavaro A,Samra Z,Sompolinsky D

    更新日期:1987-05-01 00:00:00

  • Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE.

    abstract:BACKGROUND:Serum immunoglobulin E (IgE) level is recognized to be under strong genetic control, but the causal and susceptibility genes remain to be identified. We sought to investigate the association between single nucleotide polymorphisms (SNPs) in the Toll-like receptor (TLR) signaling pathway and total serum IgE l...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2008.01889.x

    authors: Tewfik MA,Bossé Y,Lemire M,Hudson TJ,Vallée-Smejda S,Al-Shemari H,Laprise C,Desrosiers M

    更新日期:2009-05-01 00:00:00

  • The 2016 Melbourne thunderstorm asthma epidemic: Risk factors for severe attacks requiring hospital admission.

    abstract:BACKGROUND:The world's most catastrophic and deadly thunderstorm asthma epidemic struck Melbourne, Australia, on November 21, 2016. OBJECTIVE:Among thunderstorm-affected patients presenting to emergency rooms (ERs), we investigated risk factors predicting severe attacks requiring admission to hospital. METHODS:Thunde...

    journal_title:Allergy

    pub_type: 杂志文章,多中心研究

    doi:10.1111/all.13609

    authors: Hew M,Lee J,Susanto NH,Prasad S,Bardin PG,Barnes S,Ruane L,Southcott AM,Gillman A,Young A,Rangamuwa K,O'Hehir RE,McDonald C,Sutherland M,Conron M,Matthews S,Harun NS,Lachapelle P,Douglass JA,Irving L,Langton D,M

    更新日期:2019-01-01 00:00:00

  • Sustained effect of SQ-standardized grass allergy immunotherapy tablet on rhinoconjunctivitis quality of life.

    abstract:BACKGROUND:The prevalence of allergic rhinoconjunctivitis has increased significantly over the past decades with grass pollen being a common trigger. The impact of allergy on patient's quality of life is substantial. AIM:To investigate the sustained effect on quality of life during the grass pollen season 1 year after...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2009.02238.x

    authors: Frølund L,Durham SR,Calderon M,Emminger W,Andersen JS,Rask P,Dahl R

    更新日期:2010-06-01 00:00:00

  • Epidermal Langerhans cells in patients with primary Sjögren's syndrome.

    abstract::IgG-binding to the surface of Langerhans cells (LC) is a feature of primary Sjögren's syndrome and might be associated with qualitative and quantitative defects in LC. Fifteen patients with primary Sjögren's syndrome and 15 healthy controls had a punch biopsy performed from clinically unaffected skin. LC were enumerat...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1986.tb00323.x

    authors: Oxholm P,Oxholm A,Manthorpe R

    更新日期:1986-08-01 00:00:00

  • Histamine release from basophil leukocytes induced by microbial antigen preparations in patients with AIDS.

    abstract::Type I allergy against some common microorganisms was investigated in 14 patients with AIDS and 11 human immunodeficiency virus (HIV) antibody-positive homosexual men, and in a control group consisting of 13 heterosexual men without HIV antibodies. Basophil histamine release technique was used as a sensitive method to...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1987.tb02212.x

    authors: Pedersen M,Permin H,Jensen C,Stahl Skov P,Norn S,Faber V

    更新日期:1987-05-01 00:00:00

  • Mast cell activation syndromes: definition and classification.

    abstract::Mast cell activation (MCA) occurs in a number of different clinical conditions, including IgE-dependent allergies, other inflammatory reactions, and mastocytosis. MCA-related symptoms may be mild, moderate, severe, or even life-threatening. The severity of MCA depends on a number of different factors, including geneti...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/all.12126

    authors: Valent P

    更新日期:2013-04-01 00:00:00

  • Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice.

    abstract:BACKGROUND:The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be defined. Established animal models assessing the role(s) of eosinophils as contributors and/or causative agents of disease have relied on congenitally deficient mice w...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12321

    authors: Jacobsen EA,Lesuer WE,Willetts L,Zellner KR,Mazzolini K,Antonios N,Beck B,Protheroe C,Ochkur SI,Colbert D,Lacy P,Moqbel R,Appleton J,Lee NA,Lee JJ

    更新日期:2014-03-01 00:00:00

  • Repeated latex aeroallergen challenges employing a hooded exposure chamber: safety and reproducibility.

    abstract:BACKGROUND:Bronchial, nasal, and conjunctival challenges are useful for clarifying discordant clinical history (Hx) and skin and/or serologic tests and in assessing semiquantitative changes in biologic sensitivity over time. The objective of this study was to determine the safety and reproducibility of repeated latex-a...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2001.00075.x

    authors: Kurtz KM,Hamilton RG,Schaefer JA,Primeau MN,Adkinson NF Jr

    更新日期:2001-09-01 00:00:00

  • Risk of developing Parkinson's disease among patients with asthma: a nationwide longitudinal study.

    abstract:BACKGROUND:A cross-sectional retrospective study suggested a link between allergic diseases and Parkinson's disease. However, the temporal association between asthma and Parkinson's disease remains unknown. METHODS:From the Taiwan National Health Insurance Research Database, 10 455 patients who were diagnosed with ast...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12758

    authors: Cheng CM,Wu YH,Tsai SJ,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Tsai CF,Yang AC,Lin WC,Pan TL,Chang WH,Chen TJ,Chen MH

    更新日期:2015-12-01 00:00:00

  • Role of comorbid conditions in asthma hospitalizations in the south of France.

    abstract:BACKGROUND:Reasons for asthma hospitalizations are dynamic and complex. Comorbid conditions are important contributors to most chronic diseases today. We aim to characterize and describe risk factors associated with hospitalizations due to asthma in the Languedoc-Roussillon region (France) in 2009. METHODS:Programme d...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12137

    authors: Aubas C,Bourdin A,Aubas P,Gamez AS,Halimi L,Vachier I,Malafaye N,Chanez P,Molinari N

    更新日期:2013-01-01 00:00:00

  • Heat-labile Escherichia coli toxin enhances the induction of allergen-specific IgG antibodies in epicutaneous patch vaccination.

    abstract::Epicutaneous allergen-specific immunotherapy (EPIT) is proposed as an alternative route for allergen-specific immunotherapy (AIT). The induction of allergen-specific blocking IgG antibodies represents an important mechanism underlying AIT, but has not been investigated for EPIT. Here, we compared the induction of alle...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13036

    authors: Cabauatan CR,Campana R,Niespodziana K,Reinisch C,Lundberg U,Meinke A,Henning R,Neubauer A,Valenta R

    更新日期:2017-01-01 00:00:00

  • Profilin is a marker of severity in allergic respiratory diseases.

    abstract:BACKGROUND:The capacity of profilin to induce allergic symptoms in patients with respiratory allergy has been questioned. In this sense, the aim of this study was to investigate the correlation between profilin exposure and induction of symptoms in a prospective case-control study. METHODS:The concentration of profili...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.14140

    authors: Ruiz-Hornillos J,López-Matas MA,Berges Jimeno P,Henríquez A,Blanco S,Seoane-Rodríguez M,Mahíllo I,Carnés J

    更新日期:2020-04-01 00:00:00

  • Cytokine production from peripheral whole blood in atopic and nonatopic asthmatics: relationship with blood and sputum eosinophilia and serum IgE levels.

    abstract:BACKGROUND:The cytokine network is thought to be essential in orchestrating airway inflammation in asthma. Although evidence has accumulated to suggest that atopic asthma is a Th2 disease, much less is known about nonatopic asthma. METHODS:We have compared the production of IL-4, IL-6, IFN-gamma, and TNF-alpha from pe...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2000.00711.x

    authors: Bettiol J,Bartsch P,Louis R,De Groote D,Gevaerts Y,Louis E,Malaise M

    更新日期:2000-12-01 00:00:00

  • Antiallergic drugs and the immune response. Interactions and possible clinical relevance.

    abstract::Since the pharmacological treatment of allergic diseases is used in patients with alteration of the immune response due to atopy and possible concomitant infections, we have investigated the possible effects of such drugs as cromolyn, theophylline, ketotifen, oxatomide, astemizole, fenoterol, pirenzepine, and rosapros...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.1989.tb00438.x

    authors: Canonica GW,Ciprandi G

    更新日期:1989-01-01 00:00:00

  • TRPV1-mediated itch in seasonal allergic rhinitis.

    abstract:BACKGROUND:Patients with allergic rhinitis may be abnormally sensitive to stimulation of the ion channel transient receptor potential vanilloid-1 (TRPV1). AIM OF THE STUDY:To examine effects of various TRP ion channel activators on sensory symptoms in allergic rhinitis prior to and during seasonal allergen exposure. ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2009.01937.x

    authors: Alenmyr L,Högestätt ED,Zygmunt PM,Greiff L

    更新日期:2009-05-01 00:00:00

  • Allergens in house-dust samples in Germany: results of an East-West German comparison.

    abstract::The background of this study is the finding of several studies that the frequency of respiratory allergies was significantly higher in the former West Germany than the former East Germany. The present study investigated the levels of allergens of house-dust mite (Der p 1 and Der f 1), cat (Fel d 1), and cockroach (Bla...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.1999.00196.x

    authors: Fahlbusch B,Heinrich J,Gross I,Jäger L,Richter K,Wichmann HE

    更新日期:1999-11-01 00:00:00

  • Occupational type I allergy to Christmas cactus (Schlumbergera).

    abstract::The study aimed to determine whether occupational contact urticaria and symptoms of mucous membranes, reported by five workers in a cactus nursery, were due to IgE-mediated allergy to Schlumbergera cacti. The five persons had positive skin prick tests to the plants as is and positive histamine-release tests, and in th...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1997.tb01045.x

    authors: Paulsen E,Skov PS,Bindslev-Jensen C,Voitenko V,Poulsen LK

    更新日期:1997-06-01 00:00:00

  • Diagnostic workup including CD203c-based basophil activation test in immediate hypersensitivity due to metronidazole and ornidazole and evaluation of cross-reactivity in between.

    abstract:BACKGROUND:Little is known about the diagnostic approaches for immediate hypersensitivity reactions (IHRs) due to 5-nitroimidazole antibiotics. The aim was to evaluate the usefulness of in vivo tests and basophil activation test (BAT) for the diagnosis of IHRs due to metronidazole and ornidazole and to determine possib...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.14542

    authors: Beyaz Ş,Akdeniz N,Yılmaz A,Demir S,Öztop N,Çolakoğlu B,Büyüköztürk S,Deniz G,Gelincik A

    更新日期:2020-08-05 00:00:00

  • Determinants of cord-blood IgE concentrations in 6401 German neonates.

    abstract::For screening atopy risk in 6401 (84%) of all infants born during the year 1990 in six obstetric departments of five German cities, cord-blood IgE values were determined with CAP-RAST-FEIA. After cases with elevated IgA values had been excluded, 25% of the values were above the detection limit of 0.35 kU/l, and 8.5% w...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb02484.x

    authors: Bergmann RL,Schulz J,Günther S,Dudenhausen JW,Bergmann KE,Bauer CP,Dorsch W,Schmidt E,Luck W,Lau S

    更新日期:1995-01-01 00:00:00

  • Contact allergy to budesonide contained in a nasal spray.

    abstract::We describe a case of contact allergic sensitization to budesonide in a nasal spray used in the treatment of allergic rhinitis. No cross-sensitivity to other topical corticosteroids was found. ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1992.tb02392.x

    authors: Sastre J,Ibañez MD

    更新日期:1992-12-01 00:00:00

  • Exhaled nitric oxide and exercise-induced bronchoconstriction in young male conscripts: association only in atopics.

    abstract::This study was conducted to evaluate how bronchial responsiveness to direct and indirect stimuli relate to nitric oxide producing airway inflammation, and whether the relationship differs between atopic and nonatopic patients with various degrees of bronchial hyperresponsiveness and airway inflammation in a group of o...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00901.x

    authors: Rouhos A,Ekroos H,Karjalainen J,Sarna S,Sovijärvi AR

    更新日期:2005-12-01 00:00:00

  • Langerhans cells mediate the skin-induced tolerance to ovalbumin via Langerin in a murine model.

    abstract:BACKGROUND:Epicutaneous sensitization is an important route of immunization for allergens in atopic diseases; however, studies have also shown that application with protein on the intact skin induces antigen-specific tolerance. Langerhans cells (LCs) play an immunosuppressive role in several inflammatory skin diseases ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13813

    authors: Luo Y,Wang S,Liu X,Wen H,Li W,Yao X

    更新日期:2019-09-01 00:00:00

  • Efficacy and safety of the SQ-standardized grass allergy immunotherapy tablet in mono- and polysensitized subjects.

    abstract::The efficacy of single-allergen-specific immunotherapy in polysensitized subjects is a matter of debate. We therefore performed a post hoc analysis of pooled data from six randomized, double-blind, placebo-controlled trials (N = 1871) comparing the efficacy and safety of the SQ-standardized grass allergy immunotherapy...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12074

    authors: Nelson H,Blaiss M,Nolte H,Würtz SØ,Andersen JS,Durham SR

    更新日期:2013-02-01 00:00:00

  • Tomato allergy in children and young adults: cross-reactivity with latex and potato.

    abstract:BACKGROUND:Several studies have shown that allergy to natural rubber latex is associated with cross-reactivity to certain foods such as tomato and potato. The objective was to investigate the clinical and immunologic differences between a group of patients with clinical allergy to tomato and latex and another which had...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2001.00279.x

    authors: Reche M,Pascual CY,Vicente J,Caballero T,Martín-Muñoz F,Sanchez S,Martín-Esteban M

    更新日期:2001-12-01 00:00:00

  • Olive allergen-specific IgE responses in patients with Olea europaea pollinosis.

    abstract:BACKGROUND:Olive tree (Olea europaea) pollen is an important cause of pollinosis in the countries of the Mediterranean area. OBJECTIVE:This work aimed to study the IgE-binding frequency of Ole e 1, Ole e 2, Ole e 3, Ole e 6 and Ole e 7 from O. europaea pollen in a large population of olive pollen-allergic patients. M...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2002.057s71047.x

    authors: Quiralte J,Florido F,Arias de Saavedra JM,Gómez A,Sáenz de San Pedro B,González E,Rodríguez R

    更新日期:2002-01-01 00:00:00