Immunochemical characterization of reference alder (Alnus glutinosa) and hazel (Corylus avellana) pollen extracts and the partial immunochemical identity between the major allergens of alder, birch and hazel pollens.

Abstract:

:Dialysed extracts of alder (Alnus glutinosa) and hazel (Corylus avellana) pollens were characterized by immunochemical methods. The alder pollen extract contained at least 33 distinct antigens of which one, antigen 5, was classified as a major allergen, three, antigens 4, 10, and 17, were classified as intermediate allergens and two, antigens 19 and 23, were classified as minor allergens. The molecular weight and pI of the major allergen were determined to be 19,000 D and 5.2, respectively. The hazel pollen extract contained at least 40 distinct antigens, two of which were classified as major allergens, antigens 8 and 13, three as intermediate allergens, antigens 12, 17, and 26, and seven as minor allergens, antigens 6, 11, 16, 18, 29, 39, and 40. The molecular weights and pI's of the major allergens of hazel pollen were determined to be: antigen 8; Mw = 12,000 D, pI = 5.1 and less than 3.5, antigen 13; Mw = 26,000 D, pI = 5.1. Further, crossed line immunoelectrophoresis and tandem crossed immunoelectrophoresis of alder, birch and hazel strongly indicate that there exists an immunochemical partial identity between the major allergens (antigens 5 (alder), 23 (birch), and 13 (hazel)) from these tree pollens.

journal_name

Allergy

journal_title

Allergy

authors

Ipsen H,Bøwadt H,Janniche H,Nüchel Petersen B,Munch EP,Wihl JA,Løwenstein H

doi

10.1111/j.1398-9995.1985.tb00259.x

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

510-8

issue

7

eissn

0105-4538

issn

1398-9995

journal_volume

40

pub_type

杂志文章

相关文献

ALLERGY文献大全
  • Food-induced cutaneous adverse reactions.

    abstract::The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intoler...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.1998.tb04983.x

    authors: Wüthrich B

    更新日期:1998-01-01 00:00:00

  • Identification of allergen components of the opportunistic yeast Pityrosporum orbiculare by monoclonal antibodies.

    abstract::The yeast Pityrosporum orbiculare (P. orbiculare) is a member of the normal human cutaneous flora, but it is also associated with several clinical manifestations of the skin. We have previously observed IgE-binding components in P. orbiculare extracts, using sera from patients with atopic dermatitis. In the present st...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1994.tb00773.x

    authors: Zargari A,Härfast B,Johansson S,Johansson SG,Scheynius A

    更新日期:1994-01-01 00:00:00

  • Langerhans cells mediate the skin-induced tolerance to ovalbumin via Langerin in a murine model.

    abstract:BACKGROUND:Epicutaneous sensitization is an important route of immunization for allergens in atopic diseases; however, studies have also shown that application with protein on the intact skin induces antigen-specific tolerance. Langerhans cells (LCs) play an immunosuppressive role in several inflammatory skin diseases ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.13813

    authors: Luo Y,Wang S,Liu X,Wen H,Li W,Yao X

    更新日期:2019-09-01 00:00:00

  • Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases.

    abstract:BACKGROUND AND AIMS:Aspirin, a cyclo-oxygenase (COX)-1 and COX-2 inhibitor, is the antiplatelet drug of choice to prevent serious vascular events. Adverse reactions to aspirin are frequent particularly among patients with asthma, chronic rhinosinusitis and nasal polyps. COX-1 inhibitors but not COX-2 inhibitors precipi...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2007.01473.x

    authors: Fraj J,Valero A,Vives R,Pérez I,Borja J,Izquierdo I,Picado C

    更新日期:2008-01-01 00:00:00

  • Streptomycin-induced anaphylactic reaction during in vitro fertilization (IVF).

    abstract::Indications for in vitro fertilization (IVF) have been cautiously extended over the years. IVF is usually considered to be a technically complex method with only minimal side-effects. We report the case of a woman who developed an anaphylactic reaction during IVF immediately after the embryo transfer. ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1994.tb02288.x

    authors: Abeck D,Kuwert C,Segnini-Torres M,Przybilla B,Ring J

    更新日期:1994-05-01 00:00:00

  • Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis.

    abstract:BACKGROUND:New therapies are necessary to address inadequate asthma control in many patients. This study sets out to investigate whether hypoxia-inducible factor (HIF) is essential for development of allergic airway inflammation (AAI) and therefore a potential novel target for asthma treatment. METHODS:Mice conditiona...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2011.02594.x

    authors: Huerta-Yepez S,Baay-Guzman GJ,Bebenek IG,Hernandez-Pando R,Vega MI,Chi L,Riedl M,Diaz-Sanchez D,Kleerup E,Tashkin DP,Gonzalez FJ,Bonavida B,Zeidler M,Hankinson O

    更新日期:2011-07-01 00:00:00

  • Dose response relationship of allergen, histamine, and histamine releasers in skin prick test and precision of the skin prick test method.

    abstract::The aim of the present investigation was to study the dose response relationship of allergen, histamine and histamine releasers in skin prick test (SPT) and the precision of the SPT method. In one experiment timothy allergen, histamine HCl, rabbit anti-human-IgE and compound 48/80 were studied in seven patients. In a ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1987.tb02369.x

    authors: Dreborg S,Holgersson M,Nilsson G,Zetterström O

    更新日期:1987-02-01 00:00:00

  • Natural evolution of skin-test sensitivity in patients with IgE-mediated hypersensitivity to cephalosporins.

    abstract::There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospe...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12390

    authors: Romano A,Gaeta F,Valluzzi RL,Zaffiro A,Caruso C,Quaratino D

    更新日期:2014-06-01 00:00:00

  • The atopy patch test (APT)-- a useful tool for the diagnosis of food allergy in children with atopic dermatitis.

    abstract:BACKGROUND:While immediate-type clinical reactions to food can quite easily be identified by history or measurement of specific IgE in combination with positive oral food challenges, the evaluation of food allergy in the absence of immediate clinical reactions still presents diagnostic difficulties--particularly in chi...

    journal_title:Allergy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1398-9995.2000.00464.x

    authors: Niggemann B,Reibel S,Wahn U

    更新日期:2000-03-01 00:00:00

  • Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforce.

    abstract::Specific Immunotherapy for respiratory allergy is used since about one century and there is now solid documentation of its efficacy. Nevertheless, the methods and experimental designs used in clinical trials are quite heterogeneous and there is no unanimously accepted methodological standard. Many studies are planned ...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.2006.01312.x

    authors: Canonica GW,Baena-Cagnani CE,Bousquet J,Bousquet PJ,Lockey RF,Malling HJ,Passalacqua G,Potter P,Valovirta E

    更新日期:2007-03-01 00:00:00

  • Clinical significance of IgG subclass antibodies to wheat flour antigens in bakers.

    abstract::We measured the IgG subclass antibody levels to wheat flour in 42 bakers and 20 controls with an enzyme immunoassay. The levels of total IgG, IgG1 IgG2 and IgG4 antibodies were significantly higher in the bakers than in the unexposed controls. The presence of anti-wheat flour IgG subclass antibodies in the bakers was ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1990.tb00525.x

    authors: Tiikkainen U,Klockars M

    更新日期:1990-10-01 00:00:00

  • Human IgE synthesis in vitro. Detection with monoclonal antibodies.

    abstract::Using monoclonal anti-human IgE antibodies recognizing the D epsilon 1 or D epsilon 2 epitope, we have developed a sandwich radioimmunoassay (RIA) to determine IgE in human cell cultures. With the help of this assay, various methods of measuring an actual de novo IgE synthesis were compared. It was necessary to subtra...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1986.tb00327.x

    authors: Knutti-Müller JM,Stadler BM,Magnusson CM,de Weck L

    更新日期:1986-08-01 00:00:00

  • New insights into the sensitization to nonspecific lipid transfer proteins from pollen and food: New role of allergen Ole e 7.

    abstract:BACKGROUND:Ole e 7 is a nonspecific lipid transfer protein (nsLTP) from olive pollen, one of the main allergenic pollens worldwide. This allergenic nsLTP is responsible for severe symptoms in regions with high olive pollen exposure, where many Ole e 7-sensitized patients exhibit a co-sensitization to the peach nsLTP, P...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.14086

    authors: Oeo-Santos C,Navas A,Benedé S,Ruíz-León B,Díaz-Perales A,Vogel L,Moreno-Aguilar C,Jurado A,Villalba M,Barderas R

    更新日期:2020-04-01 00:00:00

  • Decongestant efficacy of desloratadine in patients with seasonal allergic rhinitis.

    abstract::Recent advances in experimental immunologic approaches to seasonal allergic rhinitis (SAR) have led to a shift in the concepts of its pathogenesis. The conventional view of SAR as a local response to inhaled allergens has largely given way to a new view of this disorder as a systemic condition with local tissue manife...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1034/j.1398-9995.2001.00102.x

    authors: Bachert C

    更新日期:2001-01-01 00:00:00

  • Detection of differentiation- and activation-linked cell surface antigens on cultured mast cell progenitors.

    abstract:BACKGROUND:Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34(+) hemopoietic progenitor cells (HPC). Depending on the stage of maturation and the environment, MC variably express differentiation- and activation-linked antigens. Little is known, however, about the ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2005.00865.x

    authors: Schernthaner GH,Hauswirth AW,Baghestanian M,Agis H,Ghannadan M,Worda C,Krauth MT,Printz D,Fritsch G,Sperr WR,Valent P

    更新日期:2005-10-01 00:00:00

  • Comparison of FEV1 and specific airway conductance in assessing airway response to occupational agents.

    abstract:BACKGROUND:There is theoretical evidence that specific airway conductance (SGaw) could be more reliable than forced expiratory volume in 1 s (FEV1) for assessing changes in airway calibre. We investigated the changes in FEV1 and SGaw when assessing bronchial responses to occupational agents. METHODS:SGaw and FEV1 were...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1046/j.1398-9995.2003.00313.x

    authors: Larbanois A,Delwiche JP,Jamart J,Vandenplas O

    更新日期:2003-12-01 00:00:00

  • Placebo-controlled challenges with perfume in patients with asthma-like symptoms.

    abstract::A group of nine patients with respiratory symptoms after nonspecific irritating stimuli, but without any IgE-mediated allergy or demonstrable bronchial obstruction, were referred to the asthma/allergy outpatient department for evaluation of suspected asthma. In order to find a provocation model and objectively assess ...

    journal_title:Allergy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.1996.tb04644.x

    authors: Millqvist E,Löwhagen O

    更新日期:1996-06-01 00:00:00

  • A specific mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy.

    abstract:BACKGROUND:It has been suggested that human breast milk oligosaccharides play a role in the development of the immune system in infants, and may consequently inhibit the onset of allergy. A specific prebiotic mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (GOS/FOS) has been shown...

    journal_title:Allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1398-9995.2008.01765.x

    authors: van Hoffen E,Ruiter B,Faber J,M'Rabet L,Knol EF,Stahl B,Arslanoglu S,Moro G,Boehm G,Garssen J

    更新日期:2009-03-01 00:00:00

  • Risk assessment for food allergy--the industry viewpoint.

    abstract::A safe food supply is a legitimate expectation of consumers, which the food industry must meet. Allergic reactions to food are recognised as a significant public health problem. Protecting allergic consumers against such reactions, while minimising the impact of food allergy on their quality of life, poses a challenge...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2001.00928.x

    authors: Crevel RW

    更新日期:2001-01-01 00:00:00

  • Bronchial challenges with aerosolized food in asthmatic, food-allergic children.

    abstract:BACKGROUND:Allergic asthma is usually considered to be provoked by aeroallergens. However, we have recently recognized a group of children with food allergies who also develop asthma when exposed to the aerosolized form of the food. METHODS:Between 1997 and 1999 we prospectively identified children with an immunoglobu...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2002.03366.x

    authors: Roberts G,Golder N,Lack G

    更新日期:2002-08-01 00:00:00

  • Fenoterol, a selective beta 2-adrenergic agonist, and inhibition of IgE-mediated basophil histamine release.

    abstract::The present study was undertaken to evaluate the effect of fenoterol, a selective beta 2-adrenergic agonist, on basophil histamine release. Fenoterol at 10(-7) to 10(-3) M did not inhibit the release of histamine induced by Dermatophagoides farinae extract (D.f.) from leukocytes from allergic patients sensitive to mit...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1987.tb00376.x

    authors: Morita Y,Miyamoto T

    更新日期:1987-10-01 00:00:00

  • Severity scoring of atopic dermatitis: a comparison of three scoring systems.

    abstract::In studies on atopic dermatitis (AD), different scoring systems are used to evaluate the severity of the disease. The objective of this study was to investigate agreement between observers in the assessment of the overall severity of AD, and interobserver variation in the assessment of severity of AD for each scoring ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1997.tb01255.x

    authors: Sprikkelman AB,Tupker RA,Burgerhof H,Schouten JP,Brand PL,Heymans HS,van Aalderen WM

    更新日期:1997-09-01 00:00:00

  • Full automation in allergy testing: measurement of specific IgE by the ENEA System.

    abstract:UNLABELLED:We evaluated the ENEA System, a fully automated instrument for the measurement of specific IgE antibodies. The instrument dispenses sera and reagents, incubates, washes, and reads and prints results automatically. The "core" of the instrument is the reactive unit called ACE (Allergy Chamber Enzymatic), which...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1995.tb01139.x

    authors: Plebani M,Faggian D,Borghesan F

    更新日期:1995-03-01 00:00:00

  • Cysteinyl-leukotriene release test (CAST) in the diagnosis of immediate drug reactions.

    abstract:BACKGROUND:The diagnosis of allergic reactions to drugs is difficult. Most skin tests are not standardized, and in vitro tests are needed to avoid provocation tests. Cross-linking of IgE on basophils is known to cause the release of both cysteinyl leukotriene (Cys-LT) and histamine. We aimed to evaluate the diagnostic ...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1034/j.1398-9995.2001.00103.x

    authors: Lebel B,Messaad D,Kvedariene V,Rongier M,Bousquet J,Demoly P

    更新日期:2001-07-01 00:00:00

  • A polymorphism in the TH 2 locus control region is associated with changes in DNA methylation and gene expression.

    abstract:BACKGROUND:Genomewide association and epigenetic studies found a region within the RAD50 gene on chromosome 5q31 to be associated with total serum IgE levels and asthma. In mice, this region harbors a locus control region for nearby TH 2 cytokines, which is characterized by four Rad50 DNase I hypersensitive sites (RHS4...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/all.12450

    authors: Schieck M,Sharma V,Michel S,Toncheva AA,Worth L,Potaczek DP,Genuneit J,Kretschmer A,Depner M,Dalphin JC,Riedler J,Frei R,Pekkanen J,Tost J,Kabesch M

    更新日期:2014-09-01 00:00:00

  • Anaphylactic shock after skin test with phytohaemoagglutinin.

    abstract::A young woman (26 years old), with gastrointestinal candidosis of 8 months duration, was hospitalized in our department to study her cell immunity. Five minutes after an id injection of PHA (bactophytohaemoagglutinin M, Difco, 1 mg), mix monilieae, mix tricophyton and PPD Berna, she showed an extensive wheal and flare...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1992.tb05099.x

    authors: Schiavino D,Nucera E,Murzilli F,Schinco G,Papa G,Fais G,Patriarca G

    更新日期:1992-04-01 00:00:00

  • Selenium and asthma: a complex relationship.

    abstract::Descriptive studies in humans investigating the relationship between selenium (Se) status and asthma have presented inconsistent results. The concept of low Se status as a potential risk factor for increased prevalence or severity of asthma is based on the role that Se, through its incorporation into selenoproteins, p...

    journal_title:Allergy

    pub_type: 评论,社论

    doi:10.1111/j.1398-9995.2008.01676.x

    authors: Hoffmann PR

    更新日期:2008-07-01 00:00:00

  • Storage mite allergy among grain elevator workers.

    abstract::A total of 139 workers (71% of the available work force) in four grain elevator stores in Aalborg, Denmark, participated in a cross-sectional study on the prevalence of storage mite allergy among grain elevator workers. All underwent interview, prick test with a standard panel of allergens and the storage mites Acarus...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.1987.tb00357.x

    authors: Revsbech P,Andersen G

    更新日期:1987-08-01 00:00:00

  • Immune mechanisms of allergen-specific sublingual immunotherapy.

    abstract::Sublingual immunotherapy has been shown in some clinical studies to modulate allergen-specific antibody responses [with a decrease in the immunoglobulin E/immunoglobulin G4 (IgE/IgG4) ratio] and to reduce the recruitment and activation of proinflammatory cells in target mucosa. Whereas a central paradigm for successfu...

    journal_title:Allergy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1398-9995.2006.01002.x

    authors: Moingeon P,Batard T,Fadel R,Frati F,Sieber J,Van Overtvelt L

    更新日期:2006-02-01 00:00:00

  • Under-report and underdiagnosis of chronic respiratory diseases in an African country.

    abstract:BACKGROUND:Chronic respiratory diseases (CRD) are greatly underestimated. The aim of this study was to assess the burden associated with reported CRD and chronic obstructive pulmonary disease, as defined on the basis of various standardized criteria, by estimating their point prevalence in a sample of individuals atten...

    journal_title:Allergy

    pub_type: 杂志文章

    doi:10.1111/j.1398-9995.2009.01956.x

    authors: Martins P,Rosado-Pinto J,do Céu Teixeira M,Neuparth N,Silva O,Tavares H,Spencer JL,Mascarenhas D,Papoila AL,Khaltaev N,Annesi-Maesano I

    更新日期:2009-07-01 00:00:00