Abstract:
:DNA sequence analysis of the nadA gene of Ehrlichia chaffeensis revealed a 942 bp open reading frame with the capacity to encode 314 amino acids. The amino acid sequence of the E. chaffeensis quinolinate synthetase A (NAD/A) has 53.6% identity and 82% similarity to the NAD A of the cyanelle of Cyanophora paradoxa. Portions of the homologous genes of E. canis and E. muris were also sequenced. The amino acid sequences of the NAD A of E. canis and E. muris have 89.2% and 93.2% homology, respectively, to the NAD A of E. chaffeensis. We propose that the nadA gene may be an excellent candidate for a genetic tool for the phylogenetic study of ehrlichiae.
journal_name
FEMS Microbiol Lettjournal_title
FEMS microbiology lettersauthors
Yu XJ,Walker DHdoi
10.1111/j.1574-6968.1997.tb12623.xsubject
Has Abstractpub_date
1997-09-01 00:00:00pages
53-8issue
1eissn
0378-1097issn
1574-6968pii
S0378-1097(97)00300-5journal_volume
154pub_type
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