Expression of primary cilia in mammalian cells.

abstract：:IPF is characterized by fibroblast accumulation, collagen deposition, and ECM remodeling, with myofibroblasts believed to be the effector cell type. Myofibroblasts develop due to EMT of lung alveolar epithelial cells, which can be induced by TGF-β. M2 macrophages, a macrophage subpopulation, secrete large amounts of T...

journal_title：Cell biology international

authors： Zhu L,Fu X,Chen X,Han X,Dong P

更新日期：2017-09-01 00:00:00

abstract：:Earlier, we have shown that spontaneously isolated non-pathogenic bacteria Serratia grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize thermolysin-like metalloproteases ECP32/grimelysin or protealysin characterized by high specificity towards actin. To address the question of w...

journal_title：Cell biology international

authors： Bozhokina ES,Tsaplina OA,Efremova TN,Kever LV,Demidyuk IV,Kostrov SV,Adam T,Komissarchik YY,Khaitlina SY

更新日期：2011-02-01 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a compression median nerve neuropathy common in women at menopausal age. The aim of this work was to study immunohistochemically the expression of estrogen (ER) and progesterone (PR) receptors in CTS and control specimens. Biopsies of transverse carpal ligament (TCL) and flexor tendon s...

journal_title：Cell biology international

authors： Toesca A,Pagnotta A,Zumbo A,Sadun R

更新日期：2008-01-01 00:00:00

abstract：:Heparin-binding epidermal growth factor (HB-EGF) is a member of highly conserved superfamily of proteins that has potential mitogenic activity and stimulates differentiation and migration of various cell types. Since HB-EGF has three intra-molecular disulfide bonds, a high expression pattern of active HB-EGF in an E. ...

journal_title：Cell biology international

authors： Khalili M,Soleyman MR,Baazm M,Beyer C

更新日期：2015-07-01 00:00:00

abstract：:The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be exp...

journal_title：Cell biology international

authors： Davis JJ,Hill HA,Powell T

更新日期：2001-01-01 00:00:00

abstract：:Transforming growth factor β1 (TGFβ1) is a negative regulator of hematopoiesis, and yet, it is frequently found at the active sites of hematopoiesis. Here, we show for the first time that bone marrow-derived mononuclear cells (BM MNCs) secrete TGFβ1 in response to erythropoietin (EPO). We further show that human bone ...

journal_title：Cell biology international

authors： Kale VP

更新日期：2020-11-01 00:00:00

abstract：:It has been demonstrated that the crude extract of mosquito larvae alters the mitotic rate of several mouse cell populations of young growing mice (25 +/- 1 days old). Furthermore, the dialysed fraction of the extract inhibited proliferation of hepatocytes from hepatectomized adult male mice (90 days old). Sampling du...

journal_title：Cell biology international

authors： Ronderos JR,Riccillo FL,Ottino A

更新日期：1996-08-01 00:00:00

abstract：:Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM) cells, including the presence of microfilaments bundles and the expression of alpha-SM actin, the actin isoform typical of contractile vascular SM cells. Myofibroblasts have been suggested to ...

journal_title：Cell biology international

authors： Desmoulière A

更新日期：1995-05-01 00:00:00

abstract：:Inflammatory cytokines exert different effects on hematopoietic stem cells (HSCs), lead to the development of various cell lineages in bone marrow (BM) and are thus a differentiation axis for HSCs. The content used in this article has been obtained by searching PubMed database and Google Scholar search engine of Engli...

journal_title：Cell biology international

authors： Najafi S,Ghanavat M,Shahrabi S,Gatavizadeh Z,Saki N

更新日期：2021-01-02 00:00:00

abstract：:TZDs (thiazolidinediones) are prescribed as anti-Type II diabetes drugs, but little is known regarding whether TZDs regulate the expression of sPLA2 (secretory phospholipase A2) in macrophages. We have investigated the effects of pioglitazone on LPS (lipopolysaccharide)-induced production of TNF-alpha (tumour necrosis...

journal_title：Cell biology international

authors： Ao C,Huo Y,Qi L,Xiong Z,Xue L,Qi Y

更新日期：2010-07-01 00:00:00

abstract：:The protein encoded by the proto-oncogene c-fos is constitutively nuclear in most cell types analyzed. It has a predicted molecular weight of about 55 kDa. Proteins with a molecular weight above 40 kDa cannot enter the nucleus passively. Our interest was to study which regions in the protein are involved in the nuclea...

journal_title：Cell biology international

authors： Campos MA,Kroon EG,Gentz R,Ferreira PC

更新日期：1999-01-01 00:00:00

abstract：:We review Don Gilbert's pioneering seminal contributions that both detailed the mathematical principles and the experimental demonstration of several of the key dynamic characteristics of life. Long before it became evident to the wider biochemical community, Gilbert proposed that cellular growth and replication neces...

journal_title：Cell biology international

authors： Gilbert K,Hammond KD,Brodsky VY,Lloyd D

更新日期：2020-06-01 00:00:00

abstract：:Temperature of culture can be used to modulate cellular metabolism for improving small intestinal cell culture and cryopreservation. An hypothermia pretreatment (2 days at 25 degrees C and 3 hours recovery at 37 degrees C) improved hamster cell survival to freeze-thaw damage (p < 0.01) but decreased the survival of 2 ...

journal_title：Cell biology international

authors： Kaeffer B,Uriel IG,Bottreau E

更新日期：1994-11-01 00:00:00

abstract：:ES (embryonic stem)-derived cells have been investigated in many animal models of severe injury and degenerative disease. However, few studies have examined the ability of ES-derived cells to improve functional outcome following partially damaged breast and also the modification of mammary tissue to produce costly pro...

journal_title：Cell biology international

authors： Huang HJ,Gao QS,Qian YG,Zhang YD,Tao BF,Xiang M,Peng J,Jiang SW,Hause B

更新日期：2010-10-01 00:00:00

abstract：:The unicellular Tetrahymena has receptors for hormones of higher vertebrates, produces these hormones, and their signal pathways are similar. The first encounter with a hormone in higher dose provokes the phenomenon of hormonal imprinting, by which the reaction of the cell is quantitatively modified. This modification...

journal_title：Cell biology international

authors： Kőhidai L,Lajkó E,Pállinger E,Csaba G

更新日期：2012-10-01 00:00:00

abstract：:The possible role of protein kinase C (PKC) and mitogen activated protein (MAP) kinases in the stimulation of cholesterol esterification by acetylated low density lipoprotein (acLDL) in human monocyte-derived macrophages (HMDM) was studied. Cholesterol esterification, as assessed by the rate of incorporation of [3H]-o...

journal_title：Cell biology international

authors： Napolitano M,Avella M,Goode NT,Botham KM,Bravo E

更新日期：2004-01-01 00:00:00

abstract：:The formation of vertebrate skeletal muscles widely thought to be under the control of hierarchy of regulatory genes. MYF5 is one of the myogenic determination gene expressed in the developing mouse dermomyotome which control skeletal muscle differentiation. In the current work, we had obtained the cDNA sequence inclu...

journal_title：Cell biology international

authors： Nie YW,Ding XB,Ge XG,Fan HL,Liu ZW,Guo H

更新日期：2013-09-01 00:00:00

abstract：:Ro52/SSA is an autoantigen that presents in patients with SS (Sjögren's syndrome) and SLE (systemic lupus erythematosus). It increases cell death and redistributes itself to apoptotic blebs, but its pro-apoptotic function has not been completely identified. Overexpression of Ro52/SSA promoted cell apoptosis induced by...

journal_title：Cell biology international

authors： Zhang J,Fang L,Zhu X,Qiao Y,Yu M,Wang L,Chen Y,Yin W,Hua ZC

更新日期：2012-05-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:A subcellular fractionation procedure was developed to isolate the different endosomal compartments present during reticulocyte maturation. After reticulocyte lysis and removal of excess haemoglobin by gel chromatography, membrane vesicles were separated over a discontinuous sucrose gradient (10-40%). Two fractions we...

journal_title：Cell biology international

authors： Dardalhon V,Géminard C,Reggio H,Vidal M,Sainte-Marie J

更新日期：2002-01-01 00:00:00

abstract：:Osteocalcin is one of the most abundant non-collagenous proteins in bone that is commonly used as a preliminary biomarker in bone formation. Osteocalcin also regulates energy metabolism as a hormone. Estrogen-related receptor alpha (ERRα) is primarily thought to regulate energy homeostasis through interacting with per...

journal_title：Cell biology international

authors： Wang H,Wang J

更新日期：2013-11-01 00:00:00

abstract：:UCB (umbilical cord blood) as a resource of MSCs (mesenchymal stem cells) is widely accepted, but the quantity and characteristics of UCB-MSCs from different gestational ages have not been well studied. We have quantified the number of MSCs in UCB at different gestational ages using a multi-colour flowcytometer and co...

journal_title：Cell biology international

authors： Ma LL,Meng FB,Shi P,Li G,Pang XN

更新日期：2012-04-01 00:00:00

abstract：:Embryonic development depends on the normal invasion of trophoblast cells. Forkhead box C2 (FOXC2) is a member of Forkhead box family, which is involved in the tumor cells invasion. The aim of this study was to explore the roles of FOXC2 on the invasion of human trophoblast cells, and further study its molecular mecha...

journal_title：Cell biology international

authors： Zhang Y,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Epithelial barrier dysfunction is involved in a large number of diseases, but the pathogenesis is unclear. Integrin alphavbeta6 (avb6) in involved in the maintenance of the mucosal homeostasis. We have investigated the role of avb6 in maintaining the epithelial barrier function. Using T84 monolayers cultures, transepi...

journal_title：Cell biology international

authors： Yu Y,Chen S,Lu GF,Wu Y,Mo L,Liu ZQ,Zheng PY,Liu Z,Yang PC

更新日期：2014-06-01 00:00:00

abstract：:Insulin resistance, diabetes and many kinds of cancers are common in overweight and obese individuals. The tumor suppressor p53 is important in securing genetic stability, but its role in the regulation of metabolic processes and cell differentiation remains unclear. We have investigated the role of p53 in adipocyte d...

journal_title：Cell biology international

authors： Huang Q,Liu M,Du X,Zhang R,Xue Y,Zhang Y,Zhu W,Li D,Zhao A,Liu Y

更新日期：2014-12-01 00:00:00

abstract：:Reactive oxygen species (ROS) are not only generated in conditions of cellular stress but are also constitutively produced in most cell types by specific metabolic processes. This research focused on a potential antioxidant Trolox (model compound for alpha-tocopherol), with the aim to establish exact mechanisms of Tro...

journal_title：Cell biology international

authors： Raspor P,Plesnicar S,Gazdag Z,Pesti M,Miklavcic M,Lah B,Logar-Marinsek R,Poljsak B

更新日期：2005-01-01 00:00:00

abstract：:Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...

journal_title：Cell biology international

authors： Zhou JX,Jia LW,Yang YJ,Peng S,Cao YJ,Duan EK

更新日期：2004-01-01 00:00:00

abstract：:Coumarin and its derivative 7-hydroxycoumarin (7-OHC) have antitumor and antimetastatic properties. The purpose of this study was to investigate the possible effects of these compounds on expression of the bcl-2 and Bax oncoproteins in two human lung cancer cell lines, A427 and Calu-1. The cells were cultured in vitro...

journal_title：Cell biology international

authors： Elinos-Báez CM,León F,Santos E

更新日期：2005-08-01 00:00:00

abstract：:It has been shown in many investigations that the abnormally increasing production and deposition of collagen is one of the important mechanisms of pathological scars and other fibrotic diseases [Wang Z, Inokuchi T, Nemoto TK, Uehara M, Baba TT. Antisense oligonucleotide against collagen-specific molecular chaperone 4...

journal_title：Cell biology international

authors： Wang Z,Li L

更新日期：2008-05-01 00:00:00