c-Jun, c-Fos and their family members activate the transcription mediated by three 21-bp repetitive sequences in the HTLV-I long terminal repeat.

Abstract:

:Transcription of human T-cell leukemia virus type I is regulated by a viral transactivatior Tax, through the 21-bp sequence in the long terminal repeat (LTR). We found that cellular transcription factor AP-1 (c-Jun/c-Fos heterocomplex) bound to the 21-bp sequence. The binding affinity of the complex increased in proportion to the number of the 21-bp sequence, and the transcriptional activation by AP-1 became evident only when the reporters had more than three 21-bp sequences. Thus, AP-1 may play a role in the viral transcription from the LTR with three 21-bp sequences in the absence of Tax, such as in the early stage of the virus infection.

journal_name

Intervirology

journal_title

Intervirology

authors

Fujii M,Tsuchiya H,Meng XB,Seiki M

doi

10.1159/000150436

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

221-8

issue

3-4

eissn

0300-5526

issn

1423-0100

journal_volume

38

pub_type

杂志文章
  • Exposure of Piglets to Enteroviruses Investigated by an Immunoassay Based on the EV-G1 VP4 Peptide.

    abstract:OBJECTIVE:The aim of this study was to investigate the exposure of piglets to enteroviruses-G (EV-G) through the presence of antibodies in their serum. METHODS:Serum samples were obtained from the vena cava of 10 piglets at 9 weeks of age and again 39 days later (day 39). They were tested using an immunoassay based on...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000449058

    authors: Benkahla MA,Sane F,Desailloud R,Hober D

    更新日期:2016-01-01 00:00:00

  • Inhibition of chemical Epstein-Barr virus induction by dimethyl sulfoxide and related polar compounds.

    abstract::Dimethyl sulfoxide and twelve related polar compounds, capable of inducing differentiation of murine erythroleukemia cells, markedly inhibited induction of Epstein-Barr virus antigens in virus producer and nonproducer lymphoblastoid cells exposed to 12-O-tetradecanoylphorbol-13-acetate, n-butyric acid, 5-iodo-2'-deoxy...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150088

    authors: Yanase S,Sugawara K

    更新日期:1989-01-01 00:00:00

  • Effects of poliovirus replication on undifferentiated and differentiated monocytic U937 cells: comparative studies with human macrophages.

    abstract::Poliovirus infection of either undifferentiated or differentiated U937 cells produced a decrease in the percentage of cells positive for the surface expression of the CD4, CD11c, CD14, or 8E11 antigens. The number of 4F2 surface molecules per cell increased in infected normal U937 cells, but was unaffected in differen...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150194

    authors: López-Guerrero JA,Cabañas C,Bernabeu C,Fresno M,Alonso MA

    更新日期:1991-01-01 00:00:00

  • Papillomavirus-like particles for serology and vaccine development.

    abstract::Genital infection with high-risk human papillomaviruses (HPV) has been etiologically linked with the development of cervical and other anogenital cancers. There is therefore a need for an effective HPV vaccine with the potential to significantly reduce the burden of more than half a million new cervical cancer cases i...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000150475

    authors: Kirnbauer R

    更新日期:1996-01-01 00:00:00

  • Syncytia Induction by Clinical Isolates of Human Respiratory Syncytial Virus A.

    abstract:OBJECTIVE:Syncytia formation is the hallmark of the cytopathic effect caused by human respiratory syncytial virus (HRSV), which is the most important viral respiratory pathogen in children. This article reports methodological improvements in primary HRSV isolation and the importance of syncytia formation and mRNA level...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000480014

    authors: Gagliardi TB,Criado MF,Proença-Módena JL,Saranzo AM,Iwamoto MA,de Paula FE,Cardoso RS,Delcaro LS,Silva ML,Câmara AA,Arruda E

    更新日期:2017-01-01 00:00:00

  • Kinetics of human antibody responses to primary genital herpes simplex virus infection.

    abstract::5 patients with primary genital herpes simplex virus (HSV) infection were studied prospectively for the production of serum antibody reactivity as measured by the virus micro-neutralization test (NT), micro-solid phase radioimmunometric assay (micro-SPRIA), and antibody-dependent cellular-cytotoxic (ADCC) test. ADCC a...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149320

    authors: Kohl S,Adam E,Matson DO,Kaufman RH,Dreesman GR

    更新日期:1982-01-01 00:00:00

  • Genomic heterogeneities in bovine herpesvirus type 1 viral isolates: a major variant selected from a field isolate.

    abstract::We have analyzed viral DNA patterns, obtained following digestion of six different infectious bovine rhinotracheitis isolates, using a panel of restriction enzymes. Several differences in profiles were observed, particularly for a Canadian viral strain which presumably contained a genome that was larger than the other...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150192

    authors: Simard C,LaBoissière S,Séguin C,Trudel M

    更新日期:1991-01-01 00:00:00

  • Progressive changes in hepatoma cells stably transfected with hepatitis B virus X gene.

    abstract:OBJECTIVE:The aim of this study is to investigate the molecular mechanism of hepatocellular carcinoma (HCC) development induced by hepatitis B virus X protein (HBx). METHODS:We previously established a H7402-X cell line that constitutively expresses HBx protein. In the present study, H7402-X gene expression profiles a...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000120289

    authors: Ye L,Dong N,Wang Q,Xu Z,Cai N,Wang H,Zhang X

    更新日期:2008-01-01 00:00:00

  • Placental and fetal pathology in intrauterine viral infections.

    abstract::Intrauterine viral infections show a wide range of fetal involvement with variable fetal outcome. The histopathologic changes of the placenta during viral infection show a wide spectrum. The most active processes are proliferative with a variety of cells involved. Vascular changes, including inflammatory and obliterat...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000024940

    authors: Horn LC,Röse I

    更新日期:1998-01-01 00:00:00

  • Cytoplasmic (but not nuclear) hepatitis B virus (HBV) core antigen reflects HBV DNA synthesis at the level of the infected hepatocyte.

    abstract::Hepatitis B virus (HBV) core antigen (HBcAg) detected by the peroxidase-antiperoxidase technique was present in the nucleus and cytoplasm of some infected hepatocytes but only in the cytoplasm of other hepatocytes. When cells expressing HBcAg were examined by in situ hybridization for the presence of HBV DNA, the intr...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149646

    authors: Gowans EJ,Burrell CJ,Jilbert AR,Marmion BP

    更新日期:1985-01-01 00:00:00

  • Emerging viruses: the case 'hantavirus'.

    abstract::This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus e...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000067924

    authors: Ulrich R,Hjelle B,Pitra C,Krüger DH

    更新日期:2002-01-01 00:00:00

  • Antigenic heterogeneity of the NS3 proteins in hepatitis C virus genotypes 1 and 6.

    abstract:OBJECTIVE:To investigate the effect of sequence variability between different genotypes of hepatitis C virus (HCV) on the antigenic properties of the NS3 proteins, and to evaluate the significance of the proteins in the serological diagnosis. METHODS:The recombinant expression plasmids of pET/NS3-1 and pET/NS3-6 were ...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000316312

    authors: Qiao W,Xie P,Cai B,Li L

    更新日期:2011-02-01 00:00:00

  • The two capsid proteins of maize rayado fino virus contain common peptide sequences.

    abstract::Virions of maize rayado fino virus (MRFV) were purified and two major capsid proteins (ca. Mr 29,000 and 22,000) were resolved by SDS-PAGE. When the two major capsid proteins were isolated from gels and compared by one-dimensional peptide mapping after digestion with Staphylococcus aureus V-8 protease, indistinguishab...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149664

    authors: Falk BW,Tsai JH

    更新日期:1986-01-01 00:00:00

  • Inhibition of Mayaro virus replication by prostaglandin A(1) in Vero cells.

    abstract::Prostaglandins exhibit antiviral activity against a wide variety of RNA and DNA viruses. In the present report, we describe the effect of cyclopentenone prostaglandin A(1) (PGA(1)) on Mayaro virus replication in Vero cells. Virus yield was significantly reduced at nontoxic concentrations which did not suppress DNA, RN...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000050069

    authors: Burlandy FM,Rebello MA

    更新日期:2001-01-01 00:00:00

  • Distribution of Hepatitis C Virus Genotypes and Subtypes in the Metropolitan Area of Naples, Italy, in the Era of Interferon-Free Regimens.

    abstract:AIMS:The objective of this work was to study the distribution of hepatitis C virus (HCV) genotypes and subtypes from 2010 to 2015 in 1,221 anti-HCV/HCV-RNA-positive specimens from patients living in the metropolitan area of Naples, since HCV genotypes and subtypes remain cornerstones in the management of chronic HCV in...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000481821

    authors: Grimaldi E,Della Pepa ME,Martora F,Magliocca P,Iovene MR,Coppola N,Donnarumma G,Galdiero M

    更新日期:2017-01-01 00:00:00

  • Epidemiology of mammalian hepatitis E virus infection.

    abstract::Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using electron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and ...

    journal_title:Intervirology

    pub_type: 杂志文章,评审

    doi:10.1159/000342301

    authors: Kaba M,Moal V,Gérolami R,Colson P

    更新日期:2013-01-01 00:00:00

  • Impairment of the M-protein and unmasking of a superficial type-specific antigen by proteolytic treatment of influenza A virions with preservation of host-specific antigenicity.

    abstract::Influenza PR8 particles resulting from strong treatment with caseinase C are spikeless, devoid of neuraminidase and hemagglutinin 1 and 2 glycopeptides, and contain a Schiff-negative polypeptide of about 13,000 molecular weight which exists as traces in intact virions. Their M-protein polypeptide content is reduced to...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149478

    authors: Reginster M,Rentier B,Dierickx L

    更新日期:1975-01-01 00:00:00

  • Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.

    abstract::We report a case in which sustained viral response was achieved after switching treatment from pegylated interferon (PEG-IFN) α-2b to α-2a and ribavirin (RBV) in patients with recurrence of hepatitis C virus (HCV) infection after living donor liver transplantation. The patient was a 62-year-old man with liver cirrhosi...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000328661

    authors: Kawaoka T,Hiraga N,Takahashi S,Takaki S,Tsuge M,Nagaoki Y,Hashimoto Y,Katamura Y,Miki D,Hiramatsu A,Waki K,Imamura M,Kawakami Y,Aikata H,Ochi H,Tashiro H,Ohdan H,Chayama K

    更新日期:2012-01-01 00:00:00

  • Interleukin 28B gene polymorphisms and Epstein-Barr virus-associated lymphoproliferative diseases.

    abstract:OBJECTIVES:Single-nucleotide polymorphisms (SNPs) near the interleukin (IL) 28B gene encoding a type III interferon (IFN-λ) are the most important genetic predictors of treatment response to hepatitis C virus (HCV). This retrospective study was undertaken to determine any association between IL28B SNPs and the developm...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000357326

    authors: Akay E,Patel M,Conibear T,Chaggar T,Haque T

    更新日期:2014-01-01 00:00:00

  • Concurrent Infection with Plasmodium vivax and the Dengue and Chikungunya Viruses in a Paediatric Patient from New Delhi, India in 2016.

    abstract::Dengue and chikungunya fevers are transmitted by the common mosquito vector Aedes and malaria by Anopheles. Concurrent infections are reported due to co-circulation of these pathogens, especially in endemic regions. We report a rare case of triple infection with 3 arthropod-borne pathogens (Plasmodium vivax and the de...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000479430

    authors: Tazeen A,Abdullah M,Hisamuddin M,Ali S,Naqvi IH,Verma HN,Ahmed A,Parveen S

    更新日期:2017-01-01 00:00:00

  • Two domains within the early coding region of SV40 involved in the transformation of human fibroblasts.

    abstract::The early gene products of simian virus 40 (SV40) transform human fibroblasts, whereas those of the human papovavirus BK (BKV) do not. The early gene products of both SV40 and BKV transform baby rat kidney cells. SV40-BKV chimerics were constructed which were able to transform baby rat kidney cells. Using the SV40-BKV...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150019

    authors: de Ronde A,Sol CJ,MacDonald ME,Koot M,ter Schegget J,van Strien A,Wouters E,van der Noordaa J

    更新日期:1987-01-01 00:00:00

  • Nonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway.

    abstract:BACKGROUND:Infection with tick-borne encephalitis virus (TBEV) causes pathological changes in the central nervous system. However, the possible redox alterations in the infected cells that can contribute to the virus pathogenicity remain unknown. OBJECTIVE:In the current study we explored the ability of TBEV nonstruct...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000452160

    authors: Kuzmenko YV,Smirnova OA,Ivanov AV,Starodubova ES,Karpov VL

    更新日期:2016-01-01 00:00:00

  • Historical Discoveries on Viruses in the Environment and Their Impact on Public Health.

    abstract:BACKGROUND:Transmission of many viruses occurs by direct transmission during a close contact between two hosts, or by an indirect transmission through the environment. Several and often interconnected factors, both abiotic and biotic, determine the persistence of these viruses released in the environment, which can las...

    journal_title:Intervirology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1159/000511575

    authors: Labadie T,Batéjat C,Leclercq I,Manuguerra JC

    更新日期:2020-01-01 00:00:00

  • Effect of gamma-interferon or cycloheximide treatment on viral and c-myc transcripts in bovine-papillomavirus-type-1-transformed primary mouse fibroblasts.

    abstract::We have studied the effect of gamma-interferon (IFN-gamma) treatment on the transcription of viral and c-myc oncogenes in bovine papillomavirus type 1 (BPV-1)-transformed mouse fibroblast cell lines. Upon IFN-gamma treatment, viral transcripts always decreased in cell lines containing episomal BPV-1 DNA, while the eff...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000150320

    authors: Agrawal R,Pelkonen J,Mäntyjärvi RA

    更新日期:1993-01-01 00:00:00

  • Antigenic variation among parainfluenza type 1 (Sendai) viruses: analysis of 6/94 virus.

    abstract::6/94 virus, isolated originally from a multiple sclerosis (MS) patient, was compared antigenically with related parainfluenza type 1 strains. These included two Sendai strains of mouse and two Sendai strains of reported human origin as well as the HA2 strain. By standard hemagglutination inhibition (HI) or hemadsorpti...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149875

    authors: Lief FS,Loh W,Meulen VT,Koprowski H

    更新日期:1975-01-01 00:00:00

  • Alternatives to the species concept for virus taxonomy.

    abstract::The species concept seems to be inescapably based on the occurrence, in a population, of regular genetic interchange which leads to the formation of common gene pools and on the presence of barriers to interchange which distinguish one gene pool from another. Present knowledge indicates that some types of viruses (e.g...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149624

    authors: Milne RG

    更新日期:1985-01-01 00:00:00

  • Antiherpetic mechanism of a sulfated derivative of Agaricus brasiliensis fruiting bodies polysaccharide.

    abstract:OBJECTIVE:To study the anti-herpes simplex virus (HSV) activity of a (1→6)-(1→3)-β-D-glucan isolated from Agaricus brasiliensis fruiting bodies (FR) as well as its chemically sulfated derivative (FR-S). METHODS:The antiherpetic activity and mechanism of action was studied by viral plaque assay applying different metho...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000365194

    authors: Cardozo FT,Camelini CM,Leal PC,Kratz JM,Nunes RJ,Mendonça MM,Simões CM

    更新日期:2014-01-01 00:00:00

  • Coxsackievirus B3 induces apoptosis in the early phase of murine myocarditis: a comparative analysis of cardiovirulent and noncardiovirulent strains.

    abstract:OBJECTIVE:To investigate the relationship between enteroviral infection and myocardial tissue apoptosis during the development of viral myocarditis in a murine model. METHODS:C3H/HeJ mice were inoculated with two strains of coxsackievirus B3, specifically CVB3 (cardiovirulent Nancy strain) and CVB3/0 (noncardiovirulen...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000071453

    authors: Joo CH,Hong HN,Kim EO,Im JO,Yoon SY,Ye JS,Moon MS,Kim D,Lee H,Kim YK

    更新日期:2003-01-01 00:00:00

  • A study of measles virus antigens in acutely and persistently infected cells using monoclonal antibodies: differences in the accumulation of certain viral proteins.

    abstract::Monoclonal antibodies were used to study measles virus (Hallé strain) infections. The distribution of virus antigens in acutely and persistently infected cells was examined by immunofluorescence, and the synthesis of the virus polypeptides in acutely infected cells was measured after immunoprecipitation and analysis i...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000149509

    authors: Giraudon P,Gerald C,Wild TF

    更新日期:1984-01-01 00:00:00

  • HLA-B alleles B*15:01 and B*15:02: opposite association with hepatitis C virus infection in Chinese voluntary blood donors.

    abstract:BACKGROUND:Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS:In this study, 426 HCV-infected and 709 uninfe...

    journal_title:Intervirology

    pub_type: 杂志文章

    doi:10.1159/000369209

    authors: Xiong H,Huang J,Rong X,Zhang M,Huang K,Xu R,Wang M,Li C,Liao Q,Xia W,Luo G,Ye X,Lu L,Fu Y,Guo T,Nelson K

    更新日期:2015-01-01 00:00:00