A common plan for dorsoventral patterning in Bilateria.

Abstract:

:Functional studies seem now to confirm, as first suggested by E. Geoffroy Saint-Hilaire in 1822, that there was an inversion of the dorsoventral axis during animal evolution. A conserved system of extracellular signals provides positional information for the allocation of embryonic cells to specific tissue types both in Drosophila and vertebrates; the ventral region of Drosophila is homologous to the dorsal side of the vertebrate. Developmental studies are now revealing some of the characteristics of the ancestral animal that gave rise to the arthropod and mammalian lineages, for which we propose the name Urbilateria.

journal_name

Nature

journal_title

Nature

authors

De Robertis EM,Sasai Y

doi

10.1038/380037a0

subject

Has Abstract

pub_date

1996-03-07 00:00:00

pages

37-40

issue

6569

eissn

0028-0836

issn

1476-4687

journal_volume

380

pub_type

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