Altered muropeptide composition in Staphylococcus aureus strains with an inactivated femA locus.

Abstract:

:Tn551 inactivation of femA, a factor involved in methicillin resistance of Staphylococcus aureus, caused the production of peptidoglycan in which the fraction of monoglycyl- and serine-containing muropeptides was increased at the expense of pentaglycyl muropeptides. femA mutants have a specific block in the biosynthesis of pentaglycine cross bridges after the addition of the first glycine residue.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

de Jonge BL,Sidow T,Chang YS,Labischinski H,Berger-Bachi B,Gage DA,Tomasz A

doi

10.1128/jb.175.9.2779-2782.1993

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

2779-82

issue

9

eissn

0021-9193

issn

1098-5530

journal_volume

175

pub_type

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