The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm.

Abstract:

:The murG gene of Escherichia coli encodes the N-acetylglucosaminyltransferase responsible for the final step in the formation of the lipid-linked disaccharide-pentapeptide subunit of peptidoglycan. Using trypsin to probe maxicell spheroplasts, we show that this enzyme is peripherally associated with the inner face of the cytoplasmic membrane. Therefore, the peptidoglycan subunit is completely assembled before it traverses the cytoplasmic membrane.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Bupp K,van Heijenoort J

doi

10.1128/jb.175.6.1841-1843.1993

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

1841-3

issue

6

eissn

0021-9193

issn

1098-5530

journal_volume

175

pub_type

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