The severity of fetal membrane infection and pregnancy complications.

Abstract:

:The purpose of this report is to examine the association of histologic chorioamnionitis with microorganisms isolated from the fetal membranes and to evaluate whether microorganisms with or without inflammation are associated with labor characteristics and with pregnancy complications. Inflammation was more common among membranes that yielded pathogenic bacteria (47%, P = 0.002) or Urea-plasma urealyticum (34%, P = 0.03) than among membranes that yielded no growth or nonpathogenic bacteria (20%). Prolonged membrane rupture (P = 0.0001), infant birth weight less than 2500 g (P = 0.02), and intraamniotic infection (P = 0.001) occurred more frequently among those women whose membranes yielded pathogenic bacteria than among those whose membranes yielded no growth or nonpathogenic bacteria. Our findings suggest that placental membranes in which pathogenic bacteria are accompanied by inflammation are associated with the highest risk of pregnancy complications.

journal_name

Ann Epidemiol

journal_title

Annals of epidemiology

authors

Krohn MA,Hillier SL,Kiviat NB,Eschenbach DA

doi

10.1016/1047-2797(93)90013-t

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

78-85

issue

1

eissn

1047-2797

issn

1873-2585

pii

1047-2797(93)90013-T

journal_volume

3

pub_type

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