Abstract：
:Intervention studies are now viewed as a useful and necessary approach to understanding the relation between nutrition and cancer. Over 20 such studies have been initiated in the past 7 years. Foreign countries may be an attractive site for such investigations, mainly because of desirable population characteristics such as unusually high rates of the cancer being studied, low dietary intake of potential chemopreventive nutrients, stability of the population, and high compliance, and also because of favorable logistical aspects including existing medical, social, or governmental structures that facilitate delivery of the intervention, ongoing cancer registries for endpoint determination, and reduced cost. The three basic elements of an intervention trial, identification and recruitment of a study population, delivery of the intervention and assessment of compliance, and ascertainment of endpoints, are the same in a foreign country as in the United States, but there are a number of special considerations, most notably communication difficulties due to language differences and distance between collaborators, which complicate foreign trials both before and during implementation. The basic elements and status of ongoing trials in China and Finland are presented.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Taylor PR,Dawsey S,Albanes Ddoi
10.1016/1047-2797(90)90010-psubject
Has Abstractpub_date
1990-12-01 00:00:00pages
195-203issue
2eissn
1047-2797issn
1873-2585pii
1047-2797(90)90010-Pjournal_volume
1pub_type
杂志文章abstract：PURPOSE:The role of estrogen in cardiovascular health remains contested with discrepancies between findings from randomized controlled trials and observational studies. Mendelian randomization, which assesses the effect of lifelong endogenous exposure, may help elucidate these discrepancies. METHODS:We used separate s...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.01.005
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:The purpose of this study is to determine whether demographics, health, and job factors influence continued participation of employed persons in a longitudinal intervention study of tertiary prevention for work-related low-back disorders (WR-LBDs). METHODS:Four hundred fifty-four actively employed persons had ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2006.07.003
更新日期：2007-01-01 00:00:00
abstract：:In a cross-sectional analytic study, we examined the differences in coronary heart disease (CHD) risk factors, including coagulation factors and platelet aggregation, among males from southern European countries and those of Anglo-Celtic descent who had widely different CHD standardized mortality ratios. The participa...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90099-c
更新日期：1992-07-01 00:00:00
abstract：PURPOSE:The natural history of the multiple metabolic syndrome (MMS) and its predictors has rarely been addressed in population samples. This study evaluated the predictive role of fasting serum insulin, body mass index (BMI), and waist-to-hip ratio (WHR) on the development of incident MMS components (diabetes, hyperte...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(97)00047-1
更新日期：1997-08-01 00:00:00
abstract：:Some of the readjustment problems of Vietnam veterans have been attributed to posttraumatic stress disorder (PTSD). This case-control study compared demographic and military characteristics of 374 Vietnam veterans who had PTSD with 373 healthy Vietnam veterans. Veterans were chosen from the Agent Orange Registry, a De...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(91)90022-5
更新日期：1991-11-01 00:00:00
abstract：PURPOSE:Prepregnancy obesity and weight changes accompanying pregnancy (gestational weight gain and postpartum weight retention) may be associated with risk of maternal depressive symptoms during pregnancy and in the postpartum. The few studies that have examined these relationships report conflicting findings. METHOD...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2017.10.007
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To estimate the effect of hypothetical changes in modifiable predictors on the incidence of fair-to-poor self-rated health (SRH) in breast cancer survivors. METHODS:In 2007-2008, we interviewed 832 breast cancer survivors 1 year after diagnosis (baseline) and 1 year later. First, multivariable logistic regress...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.10.011
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:To identify individual- and neighborhood-level correlates of membership within high HIV prevalence drug networks. METHODS:We recruited 378 New York City drug users via respondent-driven sampling (2006-2009). Individual-level characteristics and recruiter-recruit relationships were ascertained and merged with 2...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.02.006
更新日期：2013-05-01 00:00:00
abstract：:The longitudinal relationship between serum levels of lipoproteins and lifestyle measures (e.g., intake of cholesterol, carbohydrates, saturated fatty acids [SFA], polyunsaturated fatty acids [PUFA], the PUFA/SFA (P:S) ratio, alcohol consumption, smoking behavior, and daily physical activity) was investigated over a p...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(96)00003-8
更新日期：1996-05-01 00:00:00
abstract：PURPOSE:We compared overall survival and influencing factors between Asian-American women as a whole and by subgroup with white women with cervical cancer. METHODS:Cervical cancer data were from the Surveillance, Epidemiology, and End Results registry; socioeconomic information was from the Area Health Resource File. ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.10.004
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:Birth weight (BW) is associated with risk of cardiovascular (CV) disease. The findings from studies examined the association of BW with metabolic markers of CV risk were inconsistent and controversial. We examined the association of BW with insulin resistance and blood lipids using repeated measures up to mid-a...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.07.013
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:We aimed to explore the relationship between physician characteristics and their prescribing behavior regarding category D and X drugs for pregnant women by using a population-based data set in Taiwan. METHODS:The sampled population for the study included 14,430 women. These women received a total of 198,420 p...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2012.11.007
更新日期：2013-02-01 00:00:00
abstract：:A cross-sectional analysis of a sample of 3235 males and 2513 females included in a structured framework of case-control studies of various neoplasms conducted in northern Italy assessed the relationship between age at starting smoking and amount of cigarettes smoked per day. Age-standardized proportions of light, mod...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90005-1
更新日期：1994-11-01 00:00:00
abstract：:The purpose of this report is to examine the association of histologic chorioamnionitis with microorganisms isolated from the fetal membranes and to evaluate whether microorganisms with or without inflammation are associated with labor characteristics and with pregnancy complications. Inflammation was more common amon...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(93)90013-t
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:Most studies, primarily conducted in populations of European ancestry, reported increased risk of head and neck cancer (HNC) associated with leanness (body mass index [BMI] <18.5 kg/m(2)) and decreased for overweight or obesity (25.0 to <30.0 and >30 kg/m(2), respectively), compared with normal weight (18.5 to ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.11.004
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:We estimated female and male incident AIDS diagnosis rates (IARs) among people who inject drugs (PWID) in U.S. metropolitan statistical areas (MSAs) over time to assess whether declines in IARs varied by sex after combination antiretroviral therapy (cART) dissemination. METHODS:We compared IARs and 95% confide...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.01.006
更新日期：2015-04-01 00:00:00
abstract：:A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chic...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90013-g
更新日期：1992-09-01 00:00:00
abstract：PURPOSE:Using three-dimensional (3D) scanning data along with other existing subject's medical profiles to search for better anthropometric markers in association with type 2 Diabetes Mellitus (DM). METHODS:In this cross-sectional study with 6007 subjects undergoing health examination in a period of 3 years, the autho...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.04.014
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:Oxidative stress is defined as an imbalance between pro-oxidants and antioxidants. Previous research found that a single comprehensive oxidative balance score (OBS) that includes individual pro- and anti-oxidant exposures may be associated with various conditions (including prostate cancer) in the absence of as...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.02.015
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:Minority group membership in old age has been implicated as a risk factor for lower scores on cognitive function tests, independent of education level. In addition, differential rates of cognitive decline by ethnic group have been identified in several epidemiologic studies. However, others have not been able t...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2009.06.008
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:The magnitude and timing of the reported decrease in risk of renal cell carcinoma (RCC) attributed to smoking cessation is not well characterized. Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(02)00271-5
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To determine whether 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) are associated with a decreased risk of colorectal cancer. METHODS:The population included 159,219 postmenopausal women enrolled in the Women's Health Initiative in which 2000 pathologically confirmed cases of colorectal cancer wer...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.10.006
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:The purpose of this study is to map type 2 diabetes susceptibility genes in West African ancestral populations of African-Americans, through an international collaboration between West African and US investigators. DESIGN AND METHODS:Affected sib-pairs (ASP) along with unaffected spouse controls are being enro...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00180-0
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:The angiotensinogen gene (AGT), which encodes the precursor of the vasoactive hormone angiotensin II, has been reported to be associated with hypertension in Caucasian and Japanese populations. We examined the relationship between two common molecular variants of AGT, T174M and M235T and blood pressure in two c...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(98)00060-x
更新日期：1999-05-01 00:00:00
abstract：:PURPOSE: Although most US women who undergo mammography screening also receive a Clinical Breast Examination (CBE), factors that predict cancer detection during a CBE have not been well studied to date.METHODS: We analyzed 752,081 National Breast and Cervical Cancer Early Detection Program (NBCCEDP) screening records ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00099-5
更新日期：2000-10-01 00:00:00
abstract：PURPOSE:To describe factors associated with racial disparities in HIV (human immunodeficiency virus) incidence among men who have sex with men (MSM) in the United States. METHODS:In a longitudinal cohort of black and white HIV-negative MSM in Atlanta, HIV incidence rates were compared by race. Incidence hazard ratios ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.03.006
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:Exposure to nature, particularly vegetation (greenness), may be beneficial for mental health. We investigated whether higher surrounding greenness in early life was associated with subsequent reduced risk of depressive symptoms and whether this association was modified by age, sex, or population density. METHO...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.01.009
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Examine the complex relationships among metabolic syndrome components in black and white individuals by growth periods. METHODS:Path analyses of metabolic syndrome components were performed on 8203 black and white healthy subjects (64.3% white and 47.9% male) comprising children (4-11 years), adolescents (12-1...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2007.07.090
更新日期：2008-02-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the association between hardship and self-rated health among older adults and determine whether this association differed by age. METHODS:Using data from the 2014 Survey of Income and Program Participation, we conducted logistic regression analysis to examine the as...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2019.08.002
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:Childhood poverty heightens the risk of adulthood cardiovascular disease (CVD), but the underlying pathways are poorly understood. Three lifecourse models have been proposed but have never been tested among youth. We assessed the longitudinal association of childhood poverty with CVD risk factors in 10-year-o...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.05.012
更新日期：2013-08-01 00:00:00
