Platelet aggregation and coronary heart disease risk factor variation in Australian populations with different coronary heart disease mortality.

Abstract:

:In a cross-sectional analytic study, we examined the differences in coronary heart disease (CHD) risk factors, including coagulation factors and platelet aggregation, among males from southern European countries and those of Anglo-Celtic descent who had widely different CHD standardized mortality ratios. The participants included 169 men aged 40 to 49 years, 27% of whom were born in southern European countries. The subjects had no history of heart disease and no other clinical conditions, or were not taking medications known to affect hemostasis. Data obtained included their medical history and CHD-related risk behaviors, blood pressure, height, weight, abdominal and pelvic circumference, and coagulation, fibrinolysis, platelet activity, lipids, and lipoproteins profiles. There were significant differences between the two groups in the prevalence of a positive family history, mean apolipoprotein A1 levels, and platelet aggregation responses to ADP. Other established risk factors, including coagulation factor levels, were not significantly different.

journal_name

Ann Epidemiol

journal_title

Annals of epidemiology

authors

Wilson A,Leeder S,Koutts J,Heller R,Exner T,Dinale A

doi

10.1016/1047-2797(92)90099-c

keywords:

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

495-508

issue

4

eissn

1047-2797

issn

1873-2585

pii

1047-2797(92)90099-C

journal_volume

2

pub_type

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