Abstract：
PURPOSE:Massachusetts cancer registry and case-control data suggest that breast cancer incidence is elevated on Cape Cod relative to other parts of the state. We examined the association between length of residence on Cape Cod and breast cancer, since residential history could be acting as a surrogate for unidentified environmental risk factors. METHODS:We computed odds ratios (OR) and 95% confidence limits (CL) for 1121 cases occurring between 1988 and 1995 on Cape Cod and 992 controls, according to categories of residence time on Cape Cod, after adjusting for age, family history, parity and age at first live or stillbirth, education, body mass index, and breast cancer history. RESULTS:Breast cancer risk was elevated among women living on Cape Cod 5 or more years with a peak occurring in the 25 to less than 30 year category (adjusted OR=1.72; 95% CL, 1.12, 2.64). Adjusting for confounding strengthened the associations. Odds ratios did not increase monotonically over categories of longer residence. CONCLUSIONS:Our results suggest that longer residence on Cape Cod is associated with elevated breast cancer risk, however inconsistency in the pattern of association limits conclusions that might be drawn about it. Suspected environmental exposures include pesticides and drinking water contaminated by industrial, agricultural, and residential land use.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
McKelvey W,Brody JG,Aschengrau A,Swartz CHdoi
10.1016/S1047-2797(03)00120-0keywords:
subject
Has Abstractpub_date
2004-02-01 00:00:00pages
89-94issue
2eissn
1047-2797issn
1873-2585pii
S1047279703001200journal_volume
14pub_type
杂志文章abstract：PURPOSE:The angiotensinogen gene (AGT), which encodes the precursor of the vasoactive hormone angiotensin II, has been reported to be associated with hypertension in Caucasian and Japanese populations. We examined the relationship between two common molecular variants of AGT, T174M and M235T and blood pressure in two c...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(98)00060-x
更新日期：1999-05-01 00:00:00
abstract：PURPOSE:C-reactive protein (CRP), Chlamydia pneumonia, Helicobacter pylori, and cytomegalovirus (CMV) have each been associated with atherosclerosis. We assessed how infection and CRP related to risk for subsequent myocardial infarction (MI). METHODS:Using a nested case-control design, we assessed how these factors in...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(02)00276-4
更新日期：2003-03-01 00:00:00
abstract：:The Physicians' Health Study is a randomized, double-blind, placebo-controlled prevention trial of 22,071 US physicians, using a factorial design to evaluate the role of aspirin in the prevention of cardiovascular mortality and beta carotene in the reduction of cancer incidence. After approximately 5 years of follow-u...
journal_title：Annals of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/1047-2797(91)90009-2
更新日期：1991-08-01 00:00:00
abstract：:The Expanded Programme on Immunization (EPI) of the World Health Organization developed a cluster survey design for the rapid assessment of children's vaccination coverage in developing countries. Because of its simplicity and familiarity, the EPI methodology has been used for additional purposes, including the detect...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90086-8
更新日期：1994-07-01 00:00:00
abstract：PURPOSE:We sought to evaluate the association between childhood socioeconomic status (SES) at two time points and age at menarche in a multiracial sample of U.S. girls. METHODS:Our study population consisted of a cohort of female participants enrolled at birth at the New York site of the Collaborative Perinatal Projec...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.08.006
更新日期：2010-11-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.08.011
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:Local health statistics are increasingly requested for policy-making and programmatic purposes; however, population-based surveys are often inadequate to support direct estimation for small areas. Model-based estimation techniques can be used to create local estimates for public health outcomes. Using the 2014-...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.03.015
更新日期：2018-07-01 00:00:00
abstract：PURPOSE:The magnitude and timing of the reported decrease in risk of renal cell carcinoma (RCC) attributed to smoking cessation is not well characterized. Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(02)00271-5
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To provide a synthesis of current approaches to the discovery of genes associated with complex human diseases by examining the joint potential of traditional epidemiologic methods and current molecular techniques for gene discovery. METHODS:A discussion of optimal approaches for defining complex disease phenot...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/s1047-2797(98)00064-7
更新日期：1999-02-01 00:00:00
abstract：PURPOSE:To compare the estimates of HIV-related risk derived from a sample drawn through random digit dialing and that component of the sample drawn from households listed in a telephone directory. METHODS:The prevalence of key outcomes, and their 95% confidence intervals, was estimated for the total sample and for th...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.06.003
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Burden of disease (BoD) assessments typically rely on national-level incidence rates for the health outcomes of interest. The impact of using a constant national-level incidence rate, versus a more granular spatially varying rate, remains unknown and understudied in the literature. There has been an increasing ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2020.08.063
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:This study examined how race-ethnicity, nativity, and education interact to influence disparities in cardiovascular (CV) health, a new concept defined by the American Heart Association. We assessed whether race-ethnicity and nativity disparities in CV health vary by education and whether the foreign-born differ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.04.012
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:The goal of this study was to assess the relationship between hospitalization rates and asthma prevalence in New York City children and investigate the role that sociodemographic factors play in asthma. METHODS:A parent-report questionnaire was distributed in 26 randomly selected New York City public elementar...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.06.046
更新日期：2006-05-01 00:00:00
abstract：:The longitudinal relationship between serum levels of lipoproteins and lifestyle measures (e.g., intake of cholesterol, carbohydrates, saturated fatty acids [SFA], polyunsaturated fatty acids [PUFA], the PUFA/SFA (P:S) ratio, alcohol consumption, smoking behavior, and daily physical activity) was investigated over a p...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(96)00003-8
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:We sought to determine if the rate of increase in body mass index (BMI) differs between first generation immigrant children (child and both parents born outside Canada); second generation immigrant children (child born in Canada with at least one parent born outside Canada); and native-born children (child a...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.01.002
更新日期：2011-04-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.04.004
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:This cross-sectional study sought to identify diabetes accurately in a study population of 3681 women age 75 and older and to determine the association of diabetes with cognitive performance. METHODS:A previously validated test, the Telephone Interview of Cognitive Screening-Modified (TICSm) was given to asses...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/S1047-2797(03)00059-0
更新日期：2003-10-01 00:00:00
abstract：:Because of previously reported associations among the total leukocyte count, cigarette smoking, and risk of cardiovascular disease, we examined the relation of cigarette smoking to various leukocyte subpopulations among 3467 men aged 31 to 45 years. The median total leukocyte count was 36% higher (7840 vs. 5760 cells/...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(96)00024-5
更新日期：1996-07-01 00:00:00
abstract：:Intervention studies are now viewed as a useful and necessary approach to understanding the relation between nutrition and cancer. Over 20 such studies have been initiated in the past 7 years. Foreign countries may be an attractive site for such investigations, mainly because of desirable population characteristics su...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(90)90010-p
更新日期：1990-12-01 00:00:00
abstract：:In a cross-sectional analytic study, we examined the differences in coronary heart disease (CHD) risk factors, including coagulation factors and platelet aggregation, among males from southern European countries and those of Anglo-Celtic descent who had widely different CHD standardized mortality ratios. The participa...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90099-c
更新日期：1992-07-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.12.004
更新日期：2005-07-01 00:00:00
abstract：:Recent reports of increasing incidence, especially in men, led us to update through 1989 an earlier study of colorectal cancer incidence in Rochester that covered the period 1940 through 1979. The combined data reflected cancer trends in the community over half a century. Data resources of the Rochester Epidemiology P...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)00107-5
更新日期：1995-05-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(03)00055-3
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:Develop and evaluate a food frequency questionnaire (FFQ) for assessing calcium intake in Chinese postmenopausal women. METHODS:An interviewer-conducted FFQ that asks respondents about their consumption of 110 calcium-containing foods over the previous week was developed and administered to 21 randomly selecte...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(99)00055-1
更新日期：2000-04-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2003.08.005
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:Interactions between bacterial vaginosis (BV) and inflammatory sexually transmitted infections, such as gonorrhea and chlamydial infection, are not well understood. Furthermore, evidence regarding the sexual transmission of BV is equivocal. METHODS:We assessed associations between incident BV and incidences of...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.11.005
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Prescription drug overdose (PDO) deaths are a critical public health problem in the United States. This study aims to assess the association between emergency department (ED) utilization patterns in a cohort of ED patients and the risk of subsequent unintentional PDO mortality. METHODS:Using data from the New ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.03.018
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:Standard estimation of ordered odds ratios requires the constraint that the etiologic effects of exposure are homogenous across thresholds of the ordered response. We present a method to relax this often-unrealistic constraint. METHODS:The kernel of the proposed method is the expansion of observed data into "p...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2003.08.003
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:We examined whether differences in findings of studies examining mild cognitive impairment (MCI) were associated with recruitment methods by comparing sample characteristics in two contemporaneous Australian studies, using population-based and convenience sampling. METHOD:The Sydney Memory and Aging Study invi...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.10.005
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:We sought to identify factors related to total mortality in older Japanese men in Japan and Hawaii. METHODS:Baseline data were collected from 1980 to 1982 in 1379 men in Hawaii and 954 men in Japan. Ages ranged from 61 to 81 years, with mortality follow-up during a 19-year period. RESULTS:Compared with Japan,...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2008.09.004
更新日期：2008-12-01 00:00:00
