Relation between the longitudinal development of lipoprotein levels and lifestyle parameters during adolescence and young adulthood.

Abstract:

:The longitudinal relationship between serum levels of lipoproteins and lifestyle measures (e.g., intake of cholesterol, carbohydrates, saturated fatty acids [SFA], polyunsaturated fatty acids [PUFA], the PUFA/SFA (P:S) ratio, alcohol consumption, smoking behavior, and daily physical activity) was investigated over a period of 15 years in a cohort study (the Amsterdam Growth and Health Study). Members of the cohort were 13 years of age at commencement of the study and were 27 years old at termination. The unique feature of the study presented is that the longitudinal relations were analyzed with generalized estimating equations, a statistical technique in which the relations at different time-points are tested simultaneously. The development of the total serum cholesterol (TC) level was positively related to the intake of cholesterol and negatively to the P:S ratio. The development of high-density-lipoprotein cholesterol (HDL) level was positively related to alcohol consumption and daily physical activity and negatively to smoking behavior. The development of the TC:HDL ratio was negatively related to alcohol consumption and positively to both smoking behavior and carbohydrate intake.

journal_name

Ann Epidemiol

journal_title

Annals of epidemiology

authors

Twisk JW,Kemper HC,Mellenbergh GJ,van Mechelen W,Post GB

doi

10.1016/1047-2797(96)00003-8

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

246-56

issue

3

eissn

1047-2797

issn

1873-2585

pii

1047279796000038

journal_volume

6

pub_type

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