Abstract：
:We have provided recent evidence suggesting that a systematic error may be operating in prospective epidemiological mortality studies that have reported "light" or "moderate" regular use of alcohol to be "protective" against coronary heart disease. Using meta-analysis as a research tool, a hypothesis first suggested by Shaper and colleagues was tested. Shaper et al suggested that people decrease their alcohol consumption as they age and become ill or frail or increase use of medications, some people abstaining from alcohol altogether. If these people are included in the abstainer category in prospective studies, it is reasoned that it is not the absence of alcohol elevating their risk for coronary heart disease (CHD) but, rather, their ill health. Our meta-analytic results indicate that the few studies without this error (i.e., those that did not contaminate the abstainer category with occasional or former drinkers) show abstainers and "light" or "moderate" drinkers to be at equal risk for all-cause and CHD mortality. We explore the history of this hypothesis, examine challenges to our meta-analysis, and discuss options for future research.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Fillmore KM,Stockwell T,Chikritzhs T,Bostrom A,Kerr Wdoi
10.1016/j.annepidem.2007.01.005subject
Has Abstractpub_date
2007-05-01 00:00:00pages
S16-23issue
5 Suppleissn
1047-2797issn
1873-2585pii
S1047-2797(07)00007-5journal_volume
17pub_type
杂志文章,meta分析,评审abstract：PURPOSE:To carry out pattern analyses of dietary and lifestyle factors in relation to risk of esophageal and gastric cancers. METHODS:We evaluated risk factors for esophageal adenocarcinoma (EA), esophageal squamous cell carcinoma (ESCC), gastric cardia adenocarcinoma (GCA), and other gastric cancers (OGA) using data ...
journal_title：Annals of epidemiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.annepidem.2010.11.019
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:The relationship between duration of cigarette smoking and the risk of oropharyngeal cancer has not been studied in the general Japanese population. Thus, the aim of the present study was to examine the relationship between the duration of cigarette smoking and the risk of oropharyngeal cancer mortality in the ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.06.007
更新日期：2013-09-01 00:00:00
abstract：PURPOSE:This paper examines the relationship between alcohol dependence according to the criteria found in the 4th edition of the Diagnostic and Statistical Manual (DSM-IV) of the American Psychiatric Association and drinking in the U.S. general population. METHODS:The data set under analysis is the 1988 National Heal...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(97)00114-2
更新日期：1997-11-01 00:00:00
abstract：PURPOSE:To examine the association between folic acid (FA) supplementation obtained through either single FA tablets or multivitamins (MVs) and menstrual cycle characteristics among 5386 women aged 18-40 years, enrolled in an Internet-based study of Danish women attempting pregnancy during 2007-2011. METHODS:In a cros...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.05.008
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:We sought to explore the effect of economic/political factors and gender progress on femicide. METHODS:An ecological and retrospective study was undertaken that focused on 61 countries and analyzed the relationships of femicide with the following statistics from the period 1990 to 1999: economic indicators (do...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2007.11.007
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:Prior work demonstrates associations between physical abuse, household alcohol abuse, and household mental illness early in life with obesity and smoking. Studies, however, have not generally been in nationally representative samples and have not conducted analyses to account for bias in the exposure. METHODS:...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.06.003
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:While high levels of obesity prevalence and incidence have been well documented, there is less research on obesity dynamics over time. In this article, we sought to understand the body mass index (BMI) trajectories in and out of obesity from adolescence to adulthood. METHODS:We used the National Longitudinal S...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2019.12.003
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:Estimates of mammography utilization vary considerably, depending on the data source. Among women aged 65 years and older, recent estimates of annual mammography derived from the 1992 National Health Interview Survey (NHIS) were 50% higher than estimates from Medicare claims. We investigated possible reasons fo...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(98)00010-6
更新日期：1998-10-01 00:00:00
abstract：PURPOSE:The association between glycated hemoglobin (HbA1c), medication use/adherence, and mortality stratified by race/ethnicity was examined in a national cohort of veterans with type 2 diabetes. METHODS:A total of 892,223 veterans with diabetes in 2002 were followed through 2006. HbA1c category was the main exposur...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2012.11.002
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To examine the associations among Alzheimer's disease, hip fractures, and falls in elderly Canadians > or = 65 years of age (n=1513) who participated in the National Population Health Survey for Health Institutions between 1994 and 1995. METHODS:The survey was designed to provide health-related information for...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2003.08.005
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:Although prospective data are limited, recent cross-sectional studies support obesity as a cause of asthma. They also suggest that the association is present only among women. Our analysis examines possible sex-race differences in the relationship between obesity and asthma. METHODS:We examined data from the 2...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(03)00054-1
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:To examine whether smoking during first pregnancy, a time of potential vulnerability to tobacco mutagens, is associated with breast cancer. METHODS:We conducted a nested case-control study within a cohort of Washington State residents with first deliveries during 1984-1999, identified in birth and fetal death ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.09.004
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:Exposure to nature, particularly vegetation (greenness), may be beneficial for mental health. We investigated whether higher surrounding greenness in early life was associated with subsequent reduced risk of depressive symptoms and whether this association was modified by age, sex, or population density. METHO...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.01.009
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Our purpose was to investigate the complex relationship between a range of lifetime abuse experiences with current physical health and health behaviors. METHODS:Between October 1998 and May 1999, interviews were conducted with 557 ethnically diverse women seen at two urban primary care centers. Seven forms of ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(01)00243-5
更新日期：2002-02-01 00:00:00
abstract：PURPOSE:Recent U.S. guidelines redefining blood-pressure categories have generated a continuing controversy regarding the new "prehypertensive" category (systolic, 120-139, diastolic, 80-89), signifying heightened risk of progression to outright hypertension and a need for lifestyle changes and frequent follow-up. This...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.02.010
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:The goal of this study was to assess the relationship between hospitalization rates and asthma prevalence in New York City children and investigate the role that sociodemographic factors play in asthma. METHODS:A parent-report questionnaire was distributed in 26 randomly selected New York City public elementar...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.06.046
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:Consumption of foods high in glycemic index (GI) and glycemic load (GL) is associated with cardiovascular (CV) diseases in adulthood. We examined whether GI and GL predict CV risk factors in children after 2 years of follow-up. METHODS:Three 24-hour recalls were administered at baseline, and individual average...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2019.10.005
更新日期：2019-12-01 00:00:00
abstract：:The longitudinal relationship between serum levels of lipoproteins and lifestyle measures (e.g., intake of cholesterol, carbohydrates, saturated fatty acids [SFA], polyunsaturated fatty acids [PUFA], the PUFA/SFA (P:S) ratio, alcohol consumption, smoking behavior, and daily physical activity) was investigated over a p...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(96)00003-8
更新日期：1996-05-01 00:00:00
abstract：PURPOSE:To test whether female subjects in families with cleft lip and/or palate (CL/P) have an increased risk of breast cancer. METHODS:By using the Danish Facial Cleft Registry, we identified female subjects with CL/P, mothers of children with CL/P, and sisters to CL/P cases for the Danish birth cohorts 1911-1975. T...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.09.003
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Existing studies on laxatives, used by roughly 40% of the U.S. population experiencing constipation and colorectal cancer (CRC) have yielded inconsistent results, which may be due to a failure to account for differential risks by major laxative types: bulk (fiber-based), and nonbulk (or nonfiber-based). METHOD...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.06.011
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:We examined the role of smoking in the two dimensions behind the time trends in adult mortality in European countries, that is, rectangularization of the survival curve (mortality compression) and longevity extension (increase in the age-at-death). METHODS:Using data on national sex-specific populations aged 5...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.01.007
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:In prospective cohort studies, incidence is typically estimated by the ratio of the observed number of events to person-time at risk. This crude estimator is consistent for the true population incidence rate (IR) under mild assumptions. Here we consider a different setting where only cross-sectional data are av...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2020.06.005
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:We conducted this study to investigate birth seasonality in rural parts of Iran. METHODS:In this study, patterns of 5,536,262 live births in rural parts of Iran between 1992 and 2007 were studied. Information about birth numbers, environmental factors, and sociocultural status of participants was obtained from...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.09.009
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:Prepregnancy obesity and weight changes accompanying pregnancy (gestational weight gain and postpartum weight retention) may be associated with risk of maternal depressive symptoms during pregnancy and in the postpartum. The few studies that have examined these relationships report conflicting findings. METHOD...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2017.10.007
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To compare the estimates of HIV-related risk derived from a sample drawn through random digit dialing and that component of the sample drawn from households listed in a telephone directory. METHODS:The prevalence of key outcomes, and their 95% confidence intervals, was estimated for the total sample and for th...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.06.003
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To evaluate the association between physical activity (PA) across the menstrual cycle and reproductive function. METHODS:The BioCycle Study (2005-2007) followed 259 healthy premenopausal women not using hormonal contraceptives for up to two menstrual cycles (N = 509 cycles). Serum leptin, estradiol, progestero...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.11.002
更新日期：2014-02-01 00:00:00
abstract：:The objective of this study was to examine whether fasting serum insulin is a predictor of coronary heart disease in high-risk US men, and whether any such predictive role explains the enhanced cardiovascular risk seen in subjects with the apolipoprotein (Apo) E 3/2 phenotype. This was a nested case-control study of p...
journal_title：Annals of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/1047-2797(94)90041-8
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:Previous studies have shown a correlation between measures of social capital and morbidity, mortality, and violent crime. This article examines the association across U.S. states between social capital (as measured by mutual trust and civic engagement) and firearm availability. METHODS:The analysis uses OLS to...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(01)00235-6
更新日期：2001-10-01 00:00:00
abstract：:In this report, we review recent findings concerning the identification of mechanisms that may modulate the role of lipoprotein(a), or Lp(a), in thrombosis and atherogenesis. Lp(a) binds to surface-immobilized plasmin-modified fibrin, thus providing a mechanism for incorporating Lp(a) into the vessel wall. We found th...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90090-d
更新日期：1992-07-01 00:00:00
abstract：:A cross-sectional analysis of a sample of 3235 males and 2513 females included in a structured framework of case-control studies of various neoplasms conducted in northern Italy assessed the relationship between age at starting smoking and amount of cigarettes smoked per day. Age-standardized proportions of light, mod...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(94)90005-1
更新日期：1994-11-01 00:00:00
