Abstract：
PURPOSE:To test whether female subjects in families with cleft lip and/or palate (CL/P) have an increased risk of breast cancer. METHODS:By using the Danish Facial Cleft Registry, we identified female subjects with CL/P, mothers of children with CL/P, and sisters to CL/P cases for the Danish birth cohorts 1911-1975. These subjects were compared with a 5% random sample of these cohorts regarding the incidence and age of onset for breast cancer registered in the Danish Hospital Discharge Register 1977-2005. RESULTS:Examining 48,404 person-years for 1809 female CL/P cases (49 breast cancer cases) and 212,795 person-years for 7935 female relatives (188 breast cancer cases), we found no increased breast cancer risk for either CL/P cases (hazard ratio [HR], 1.23; 95% confidence interval (CI), 0.92-1.63), mothers of children with CL/P (HR, 0.93; 95% CI, 0.80-1.08), or sisters of CL/P cases (HR, 0.94; 95% CI, 0.55-1.60), nor was there any significant differences in age of onset. CONCLUSION:Both epidemiological and genetic studies have suggested common etiological factors for breast cancer and CL/P. However, in this population-based study we were not able to confirm a general increase in the risk of breast cancer among female subjects in families with CL/P.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Dietz A,Pedersen DA,Jacobsen R,Wehby GL,Murray JC,Christensen Kdoi
10.1016/j.annepidem.2011.09.003subject
Has Abstractpub_date
2012-01-01 00:00:00pages
37-42issue
1eissn
1047-2797issn
1873-2585pii
S1047-2797(11)00283-3journal_volume
22pub_type
杂志文章abstract：PURPOSE:Minority group membership in old age has been implicated as a risk factor for lower scores on cognitive function tests, independent of education level. In addition, differential rates of cognitive decline by ethnic group have been identified in several epidemiologic studies. However, others have not been able t...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2009.06.008
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:To examine the clustering and patterns of obesity-related behaviors in children and their mothers and the concordance between mother and child pairs. METHODS:Primary school-aged children and their mothers in Victoria, Australia, participated (data from 549 mothers, 352 children, and 304 mother/child pairs). Ex...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.11.001
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:A review of recent threats and challenges to epidemiology suggests that some represent an opportunity to advance the discipline while others are a major threat to conducting epidemiologic work. METHODS:Two issues are identified which should advance the publication and conduct of epidemiologic research. Three a...
journal_title：Annals of epidemiology
pub_type：
doi：10.1016/s1047-2797(97)00206-8
更新日期：1998-02-01 00:00:00
abstract：PURPOSE:Oxidative stress is defined as an imbalance between pro-oxidants and antioxidants. Previous research found that a single comprehensive oxidative balance score (OBS) that includes individual pro- and anti-oxidant exposures may be associated with various conditions (including prostate cancer) in the absence of as...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.02.015
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:Population-based cancer incidence rates of the corpus uteri, cervix uteri, and ovaries are underestimated if they fail to remove women not at risk for developing the cancers from the denominator in the race calculation. This study compares incidence rates among selected racial groups for these cancers before an...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2006.06.001
更新日期：2006-12-01 00:00:00
abstract：PURPOSE:Social and economic contextual factors may promote concurrent sexual partnerships, which can accelerate population HIV transmission and are more common among African Americans than U.S. Whites. We investigated the relationship between contextual factors and concurrency. METHODS:We analyzed past 12-month concur...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.08.002
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:The role of estrogen in cardiovascular health remains contested with discrepancies between findings from randomized controlled trials and observational studies. Mendelian randomization, which assesses the effect of lifelong endogenous exposure, may help elucidate these discrepancies. METHODS:We used separate s...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.01.005
更新日期：2016-03-01 00:00:00
abstract：:Elevated blood pressure is a highly prevalent condition that is etiologically related to coronary heart disease and stroke, two of the leading causes of morbidity and mortality throughout the world. Excess salt (sodium chloride) intake is a major determinant of elevated blood pressure. In this article, we discuss the ...
journal_title：Annals of epidemiology
pub_type： 历史文章,杂志文章
doi：10.1016/j.annepidem.2012.04.003
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Few studies have examined methods of contraception, beyond oral contraceptives (OCs) and tubal ligation, in relation to ovarian cancer risk. METHODS:Nine hundred two cases with incident ovarian/peritoneal/tubal cancer were compared with 1800 population-based control subjects. Women self-reported all methods of...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.10.002
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:Both obesity and gamma glutamyltransferase (GGT) are individually considered to be closely associated with metabolic syndrome (MetS). Whether the 2 factors synergistically associate with MetS is not yet confirmed. The purpose of this study was to investigate whether obesity and GGT are interactively associated ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2012.09.012
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:Existing studies on laxatives, used by roughly 40% of the U.S. population experiencing constipation and colorectal cancer (CRC) have yielded inconsistent results, which may be due to a failure to account for differential risks by major laxative types: bulk (fiber-based), and nonbulk (or nonfiber-based). METHOD...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.06.011
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:Although much value has been placed on type I error event probabilities in clinical trials, interpretive difficulties often arise that are directly related to clinical trial complexity. Deviations of the trial execution from its protocol, the presence of multiple treatment arms, and the inclusion of multiple en...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/s1047-2797(98)00003-9
更新日期：1998-08-01 00:00:00
abstract：PURPOSE:To examine the associations between social class at ages 0, 5, 10, 30, and 34 years and physical activity at age 34 years using a novel approach to analysis of life course data. METHODS:We used structural equation modeling to compare three competing models in life course epidemiology: the accumulation of risk ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.06.096
更新日期：2014-09-01 00:00:00
abstract：:PURPOSE: To present the parallel histories of epidemiologic and electronic publishing and consider positive and negative factors that might affect their amalgam.METHODS: We performed a quantitative assessment of the arc of epidemiologic publication from 1966-1999, using major self-designated epidemiologic journals as ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00096-x
更新日期：2000-10-01 00:00:00
abstract：PURPOSE:To investigate the distribution of mesothelioma in Flanders using Bayesian disease mapping models that account for both an excess of zeros and overdispersion. METHODS:The numbers of newly diagnosed mesothelioma cases within all Flemish municipalities between 1999 and 2008 were obtained from the Belgian Cancer ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.10.006
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Incidence studies of occupational factors and cancer in the United States are problematic because the use of population-based registries to identify cases requires development of historical data on subjects' residences and often severely restricts the time period of follow up. This article describes procedures ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.06.055
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:The magnitude and timing of the reported decrease in risk of renal cell carcinoma (RCC) attributed to smoking cessation is not well characterized. Furthermore, conclusions from previous investigations have been hampered by unstable risk estimates, broad exposure categories and/or insufficient adjustment for the...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(02)00271-5
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To describe long-term trends in tuberculosis (TB) mortality and to compare trends estimated from two different sources of public health surveillance data. METHODS:Trends and changes in trend were estimated by joinpoint regression. Comparisons between data sets were made by fitting a Poisson regression model. ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.07.002
更新日期：2011-10-01 00:00:00
abstract：PURPOSE:The purpose of this study was to investigate the association of early social environment with Kawasaki disease (KD). METHODS:We analyzed the data of children aged up to 10 years derived from the 21st Century Longitudinal Survey in Newborns (n = 41,872) in Japan. Parental education, total household income, and ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.10.010
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:We sought to determine if the rate of increase in body mass index (BMI) differs between first generation immigrant children (child and both parents born outside Canada); second generation immigrant children (child born in Canada with at least one parent born outside Canada); and native-born children (child a...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.01.002
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:Breast density and body mass index (BMI) are correlated attributes and are both potentially modifiable risk factors for breast cancer. However, relationships between these factors and risk of molecularly-defined subtypes of breast cancer have not been established. METHODS:We used breast density and BMI data co...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2012.02.002
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Prescription drug overdose (PDO) deaths are a critical public health problem in the United States. This study aims to assess the association between emergency department (ED) utilization patterns in a cohort of ED patients and the risk of subsequent unintentional PDO mortality. METHODS:Using data from the New ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2015.03.018
更新日期：2015-08-01 00:00:00
abstract：:In Japan, stroke now ranks third among all causes of death following cancer and heart disease. Stroke was the leading cause of death for 3 decades after 1951. Stroke mortality tended to increase until about 1970, but it decreased and yielded first place to cancer in 1981. Heart disease deaths outnumbered stroke deaths...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(93)90109-h
更新日期：1993-09-01 00:00:00
abstract：PURPOSE:We investigated understudied biomarker-based diabetes among young US adults, traditionally characterized by low cardiovascular disease risk. METHODS:We examined 15,701 participants aged 24 to 32 years at Wave IV of the National Longitudinal Study of Adolescent Health (Add Health, 2008). The study used innovati...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.09.010
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:Most studies, primarily conducted in populations of European ancestry, reported increased risk of head and neck cancer (HNC) associated with leanness (body mass index [BMI] <18.5 kg/m(2)) and decreased for overweight or obesity (25.0 to <30.0 and >30 kg/m(2), respectively), compared with normal weight (18.5 to ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.11.004
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:The purpose of this study was to describe time trends in response rates in case-control studies of cancer and identify study design factors that influence response rate. METHODS:We reviewed 370 case-control studies of cancer published in 12 journals during indicator years in each of the last four decades. We e...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.04.001
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To demonstrate how principal components analysis can be used to describe patterns of weight changes in response to an intensive lifestyle intervention. METHODS:Principal components analysis was applied to monthly percent weight changes measured on 2,485 individuals enrolled in the lifestyle arm of the Action f...
journal_title：Annals of epidemiology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.annepidem.2009.06.001
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:Acute cardiovascular events such as heart attack and stroke in commercial pilots have been a concern to flight safety. The purpose of this study was to examine the association of body mass index (BMI) with cardiovascular disease in commercial pilots. METHODS:We followed from 1987 to 1997 a cohort of 3019 male ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2004.08.002
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:We analyzed the changes in the body mass index (BMI) distribution for urban Australian adults between 1980 and 2007. METHODS:We used data from participants of six consecutive Australian nation-wide surveys with measured weight and height between 1980 and 2007. We used quantile regression to estimate mean BMI (...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.10.008
更新日期：2015-01-01 00:00:00
abstract：:Characterization of nonrespondents, with the aim of detecting nonresponse bias, is a crucial component of prospective studies. This study was undertaken to investigate the demographic and health characteristics of nonrespondents to a population-based cohort study of cardiovascular disease, to determine whether early-s...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(96)00104-4
更新日期：1996-11-01 00:00:00
