Abstract：
PURPOSE:We investigated understudied biomarker-based diabetes among young US adults, traditionally characterized by low cardiovascular disease risk. METHODS:We examined 15,701 participants aged 24 to 32 years at Wave IV of the National Longitudinal Study of Adolescent Health (Add Health, 2008). The study used innovative and relatively noninvasive methods to collect capillary whole blood via finger prick at in-home examinations in all 50 states. RESULTS:Assays of dried blood spots produced reliable and accurate values of HbA1c. Reliability was lower for fasting glucose and lowest for random glucose. Mean (SD) HbA1c was 5.6% (0.8%). More than a quarter (27.4%) had HbA1c-defined prediabetes. HbA1c was highest in the black, non-Hispanic race/ethnic group, inversely associated with education, and more common among the overweight/obese and physically inactive. The prevalence of diabetes defined by previous diagnosis or use of antidiabetic medication was 2.9%. Further incorporating HbA1c and glucose values, the prevalence increased to 6.8%, and among these participants, 38.9% had a previous diagnosis of diabetes (i.e., aware). Among those aware, 37.6% were treated and 64.0% were controlled (i.e., HbA1c < 7%). CONCLUSIONS:A contemporary cohort of young adults faces a historically high risk of diabetes but there is ample opportunity for early detection and intervention.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Nguyen QC,Whitsel EA,Tabor JW,Cuthbertson CC,Wener MH,Potter AJ,Halpern CT,Killeya-Jones LA,Hussey JM,Suchindran C,Harris KMdoi
10.1016/j.annepidem.2014.09.010subject
Has Abstractpub_date
2014-12-01 00:00:00pages
903-9.e1issue
12eissn
1047-2797issn
1873-2585pii
S1047-2797(14)00415-3journal_volume
24pub_type
杂志文章abstract：PURPOSE:The aim of the study was to assess the relationship between age of arrival of male pediatric immigrant populations in Israel and their risk for subsequent high-weight morbidity at adolescence. METHODS:The study analyzed a pooled cross section of 89,744 foreign-born male Jewish study participants, who were born...
journal_title：Annals of epidemiology
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更新日期：2014-06-01 00:00:00
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journal_title：Annals of epidemiology
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pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期：2012-03-01 00:00:00
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更新日期：2013-09-01 00:00:00
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journal_title：Annals of epidemiology
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更新日期：2014-08-01 00:00:00
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更新日期：2011-12-01 00:00:00
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更新日期：2000-08-01 00:00:00
