Abstract：
OBJECTIVES:Information on the epidemiology of end-stage liver disease (ESLD) in US correctional populations is limited. We examined the prevalence, mortality and clinical characteristics of ESLD in the nation's second largest state prison system. METHODS:We collected and analyzed medical and demographic data from 370,511 offenders incarcerated in Texas' prison system during a 3.5-year period. RESULTS:ESLD was diagnosed in 484 inmates (131/100,000); 213 (57/100,000) died of ESLD. Offenders who were Hispanic, 30-49 years of age, > or =50 years of age, HIV monoinfected, hepatitis C virus (HCV) monoinfected, or HIV/HCV coinfected had elevated ESLD prevalence and mortality rates. CONCLUSIONS:ESLD mortality in Texas' prison population is approximately 3 times higher than that of the general population, reflecting elevated rates of HCV and HIV/HCV coinfection among prisoners. Ultimately, the only viable treatment option for many prisoners with ESLD will be liver transplantation. The enormous costs of organ transplantation and immunosuppressive therapy are staggering and have the potential to decimate the healthcare budgets of most prison systems. Consequently, it is imperative that correctional healthcare programs expand HCV treatment and prevention strategies.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Baillargeon J,Soloway RD,Paar D,Giordano TP,Murray O,Grady J,Williams B,Pulvino J,Raimer BGdoi
10.1016/j.annepidem.2007.04.005subject
Has Abstractpub_date
2007-10-01 00:00:00pages
808-13issue
10eissn
1047-2797issn
1873-2585pii
S1047-2797(07)00180-9journal_volume
17pub_type
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journal_title：Annals of epidemiology
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journal_title：Annals of epidemiology
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journal_title：Annals of epidemiology
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更新日期：2012-01-01 00:00:00
