Abstract：
PURPOSE:Prior work demonstrates associations between physical abuse, household alcohol abuse, and household mental illness early in life with obesity and smoking. Studies, however, have not generally been in nationally representative samples and have not conducted analyses to account for bias in the exposure. METHODS:We used data from the 1979 U.S. National Longitudinal Survey of Youth to test associations between measures of adverse childhood experiences with obesity and smoking and used an instrumental variables approach to address potential measurement error of the exposure. RESULTS:Models demonstrated associations between childhood physical abuse and obesity at age 40 years (odds ratio [OR] 1.23; 95% confidence interval [CI], 1.00-1.52) and ever smoking (OR 1.83; 95% CI, 1.56-2.16), as well as associations between household alcohol abuse (OR 1.53; 95% CI, 1.31-1.79) and household mental illness (OR 1.29; 95% CI, 1.04-1.60) with ever smoking. We find no evidence of association modification by gender, socioeconomic position, or race and/or ethnicity. Instrumental variables analysis using a sibling's report of adverse childhood experiences demonstrated a relationship between household alcohol abuse and smoking, with a population attributable fraction of 17% (95% CI, 2.0%-37%) for ever smoking and 6.7% (95% CI, 1.6%-12%) for currently smoking. CONCLUSIONS:Findings suggest long-term impacts of childhood exposure to physical abuse, household alcohol abuse, and parental mental illness on obesity and smoking and that the association between household alcohol abuse and smoking is not solely due to measurement error.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Rehkopf DH,Headen I,Hubbard A,Deardorff J,Kesavan Y,Cohen AK,Patil D,Ritchie LD,Abrams Bdoi
10.1016/j.annepidem.2016.06.003subject
Has Abstractpub_date
2016-07-01 00:00:00pages
488-492.e5issue
7eissn
1047-2797issn
1873-2585pii
S1047-2797(16)30160-0journal_volume
26pub_type
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journal_title：Annals of epidemiology
pub_type： 杂志文章
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journal_title：Annals of epidemiology
pub_type： 杂志文章
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更新日期：2010-12-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 历史文章,杂志文章
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更新日期：2000-10-01 00:00:00
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更新日期：2020-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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更新日期：2013-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-09-01 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2008-11-01 00:00:00
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更新日期：2013-05-01 00:00:00
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journal_title：Annals of epidemiology
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更新日期：2015-11-01 00:00:00
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journal_title：Annals of epidemiology
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更新日期：2006-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2006-05-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
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更新日期：2017-10-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(01)00243-5
更新日期：2002-02-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2007.06.004
更新日期：2007-11-01 00:00:00
