Path analysis of metabolic syndrome components in black versus white children, adolescents, and adults: the Bogalusa Heart Study.


PURPOSE:Examine the complex relationships among metabolic syndrome components in black and white individuals by growth periods. METHODS:Path analyses of metabolic syndrome components were performed on 8203 black and white healthy subjects (64.3% white and 47.9% male) comprising children (4-11 years), adolescents (12-18 years), and adults (19-44 years). RESULTS:The direct effect of body mass index (BMI) on fasting insulin levels was greatest among all the paths for each age group in both races. In general, path coefficients were greater in whites than in blacks except for the age-mean arterial pressure (MAP) path and greater in children and adults than in adolescents. The direct age effect on MAP was greater in black versus white adults (p = 0.010 for race difference). Whites showed greater direct effects of BMI on MAP in children (p = 0.007), adolescents (p = 0.090), and adults (p = 0.022); BMI on insulin in adolescents (p < 0.001); BMI on triglycerides in children (p = 0.003); and insulin on triglycerides in adults (p < 0.001). A race difference in the effect of BMI on fasting glucose was noted among adolescents (p = 0.048). CONCLUSIONS:The black-white differences in the relationships of obesity and insulin resistance measures to other components may account for the lower prevalence of metabolic syndrome in the black population.


Ann Epidemiol


Annals of epidemiology


Chen W,Srinivasan SR,Berenson GS




Has Abstract


2008-02-01 00:00:00














  • Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study.

    abstract:PURPOSE:Determinants of oxidative capacity, such as fitness and level of adiposity, are strongly associated with type 2 diabetes. Whether decreased oxidative capacity itself is a cause or consequence of insulin resistance and diabetes is unknown. METHODS:We examined the association of plasma lactate, a marker of oxida...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Juraschek SP,Selvin E,Miller ER,Brancati FL,Young JH

    更新日期:2013-12-01 00:00:00

  • Cigarette smoking and risk of pancreatic cancer: a clinic-based case-control study in the San Francisco Bay Area.

    abstract:PURPOSE:Cigarette smoking is an established risk factor for pancreatic cancer (PC). We examined the association between cigarette smoking and PC in a San Francisco Bay Area clinic-based, case-control study. METHODS:A total of 536 cases and sex and age frequency-matched controls (n = 869) were recruited predominately f...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Lea CS,Holly EA,Bracci PM

    更新日期:2015-11-01 00:00:00

  • Diabetes is more lethal in Mexicans and Mexican-Americans compared to Non-Hispanic whites.

    abstract:PURPOSE:To examine the mortality risk associated with diabetes in the Mexico City Diabetes Study (MCDS) and the San Antonio Heart Study (SAHS). METHODS:Prospective cohorts conducted 1990-2007 in MCDS and 1979-2000 in SAHS. Mortality risk was examined using Cox proportional hazard models in 1402 non-Hispanic whites (NH...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Hunt KJ,Gonzalez ME,Lopez R,Haffner SM,Stern MP,Gonzalez-Villalpando C

    更新日期:2011-12-01 00:00:00

  • Maternal Zika virus infection and newborn microcephaly-an analysis of the epidemiological evidence.

    abstract:PURPOSE:To evaluate whether existing data and evidence support a causal link between maternal Zika virus (ZIKV) infection and newborn microcephaly. METHODS:I quantified and compared the prevalence of all and severe microcephaly in Brazil, during and before 2015-2016, to assess whether an outbreak has occurred, used ti...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章,评审


    authors: Bautista LE

    更新日期:2018-02-01 00:00:00

  • Associations of blood heavy metal levels with intraocular pressure.

    abstract:PURPOSE:Whether or which blood heavy metal levels (BHMLs) influence elevating intraocular pressure (IOP) are unknown. We examined the relationship among blood lead, mercury, and cadmium levels, blood pressure (BP), and IOP and assessed whether BP mediates these BHMLs-IOP associations. METHODS:We analyzed data on 8371 ...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Park S,Choi NK

    更新日期:2016-08-01 00:00:00

  • Mammography screening guidelines for women 40 to 49 and over 65 years old.

    abstract::Many organizations in the United States recommend mammography screening at 1- to 2-year intervals for those 40 to 49 years old. In most areas of Canada and Europe, screening mammography is not recommended for women 40 to 49 years old. These differences have arisen over interpretation of data from the Health Insurance ...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Miller AB

    更新日期:1994-03-01 00:00:00

  • Prevalence and characteristics of children with autism-spectrum disorders.

    abstract:PURPOSE:The purpose of this study was to determine the prevalence of autism spectrum disorders (ASD) and associated characteristics among 8-year-old children. METHODS:This is an ongoing active, population-based surveillance program conducted in South Carolina as part of the Centers for Disease Control and Prevention's...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Nicholas JS,Charles JM,Carpenter LA,King LB,Jenner W,Spratt EG

    更新日期:2008-02-01 00:00:00

  • The role of obesity in the risk of gestational diabetes among immigrant and U.S.-born women in New York City.

    abstract:PURPOSE:To examine if the role of obesity in the risk of gestational diabetes differs between immigrant and U.S.-born women. METHODS:We used New York City-linked 2010-2014 birth certificate and hospital data. We created four racial/ethnic groups (non-Hispanic black, Hispanic, non-Hispanic white, and Asian) and three s...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Janevic T,Zeitlin J,Egorova N,Balbierz A,Howell EA

    更新日期:2018-04-01 00:00:00

  • Adverse childhood experiences and later life adult obesity and smoking in the United States.

    abstract:PURPOSE:Prior work demonstrates associations between physical abuse, household alcohol abuse, and household mental illness early in life with obesity and smoking. Studies, however, have not generally been in nationally representative samples and have not conducted analyses to account for bias in the exposure. METHODS:...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Rehkopf DH,Headen I,Hubbard A,Deardorff J,Kesavan Y,Cohen AK,Patil D,Ritchie LD,Abrams B

    更新日期:2016-07-01 00:00:00

  • Epidemiologic features of HTLV-II: serologic and molecular evidence.

    abstract:PURPOSE:A literature review was performed of the three principal subpopulations most commonly associated with human T-cell lymphotropic virus type II (HTLV-II) with the view of identifying the prevalence and transmission routes of HTLV-II. These included blood donors (BDs), intravenous drug users (IVDUs), and Amerindia...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章,评审


    authors: Lowis GW,Sheremata WA,Minagar A

    更新日期:2002-01-01 00:00:00

  • Platelet aggregation and coronary heart disease risk factor variation in Australian populations with different coronary heart disease mortality.

    abstract::In a cross-sectional analytic study, we examined the differences in coronary heart disease (CHD) risk factors, including coagulation factors and platelet aggregation, among males from southern European countries and those of Anglo-Celtic descent who had widely different CHD standardized mortality ratios. The participa...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Wilson A,Leeder S,Koutts J,Heller R,Exner T,Dinale A

    更新日期:1992-07-01 00:00:00

  • Early-life antecedents of atrial fibrillation: place of birth and atrial fibrillation-related mortality.

    abstract:PURPOSE:Recent evidence suggests early-life factors correlate with atrial fibrillation (AF). We hypothesized that AF-related mortality, similar to stroke mortality, is elevated for individuals born in the southeastern United States. METHODS:We estimated 3-year (1999-2001) average AF-related mortality rates by using U....

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Patton KK,Benjamin EJ,Kosheleva A,Curtis LH,Glymour MM

    更新日期:2011-10-01 00:00:00

  • Severe maternal morbidity among U.S.- and foreign-born Asian and Pacific Islander women in California.

    abstract:PURPOSE:The purpose of the study was to examine the risk of severe maternal morbidity (SMM)-a composite of serious, potentially life-threatening conditions related to childbirth-among subgroups of nulliparous women with Asian and Pacific Islander race/ethnicity. METHODS:This study used linked hospital discharge and vi...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Wall-Wieler E,Bane S,Lee HC,Carmichael SL

    更新日期:2020-12-01 00:00:00

  • Gestational weight gain and birth outcome in relation to prepregnancy body mass index and ethnicity.

    abstract:PURPOSE:The obesity epidemic raises concerns about the impact of excessive and insufficient weight gain during pregnancy. METHODS:We examined the association between gestational weight gain (GWG) and preterm birth, term small- and large-for-gestational-age (SGA and LGA), term birthweight, and term primary Cesarean del...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Savitz DA,Stein CR,Siega-Riz AM,Herring AH

    更新日期:2011-02-01 00:00:00

  • Prevalence of non-traditional cardiovascular disease risk factors among persons with impaired fasting glucose, impaired glucose tolerance, diabetes, and the metabolic syndrome: analysis of the Third National Health and Nutrition Examination Survey (NHANES

    abstract:PURPOSE:To calculate the prevalence of non-traditional cardiovascular disease (CVD) risk factors across diabetes status and for persons with and without the metabolic syndrome. METHODS:Data were analyzed from the Third National Health and Nutrition Examination Survey for normal plasma glucose [<100 mg/dl, n=4589]; imp...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Muntner P,He J,Chen J,Fonseca V,Whelton PK

    更新日期:2004-10-01 00:00:00

  • Validation of a food-frequency questionnaire to assess dietary intakes in cancer studies in Italy. Results for specific nutrients.

    abstract::The validity of a 77-item food-frequency questionnaire (FFQ) developed for a multicenter case-control study on diet and cancer in Italy was assessed. Trained interviewers administered the same FFQ to 452 volunteers from three Italian provinces (Pordenone, Genoa, and Forli) completed in two different seasons, at an int...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Decarli A,Franceschi S,Ferraroni M,Gnagnarella P,Parpinel MT,La Vecchia C,Negri E,Salvini S,Falcini F,Giacosa A

    更新日期:1996-03-01 00:00:00

  • Measurement of lactose consumption reliability and comparison of two methods.

    abstract::The objective of this study was to assess the reliability of lactose consumption measured with a food-frequency questionnaire and to compare food-frequency data to prospectively recorded data. A self-administered food-frequency questionnaire (FF1) was completed by 295 women ages 38 to 49. Two months later, 75 received...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Cooper GS,Busby MG,Fairchild AP

    更新日期:1995-11-01 00:00:00

  • Cigarette smoking and leukocyte subpopulations in men.

    abstract::Because of previously reported associations among the total leukocyte count, cigarette smoking, and risk of cardiovascular disease, we examined the relation of cigarette smoking to various leukocyte subpopulations among 3467 men aged 31 to 45 years. The median total leukocyte count was 36% higher (7840 vs. 5760 cells/...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Freedman DS,Flanders WD,Barboriak JJ,Malarcher AM,Gates L

    更新日期:1996-07-01 00:00:00

  • Use of the case-crossover design to study prolonged drug exposures and insidious outcomes.

    abstract:PURPOSE:The case-crossover design was originally intended to study brief exposures with immediate and transient effects, and acute outcomes with abrupt onsets. We investigated whether case-crossover methods can be used to study prolonged exposures and insidious outcomes. METHODS:We conducted a case-crossover study of ...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Wang PS,Schneeweiss S,Glynn RJ,Mogun H,Avorn J

    更新日期:2004-04-01 00:00:00

  • Extreme maternal education and preterm birth: time-to-event analysis of age and nativity-dependent risks.

    abstract:PURPOSE:Increasing numbers of women achieve extremely high education, but the association with preterm birth (PTB) is poorly understood, especially over the life course. We sought to determine how very high educational attainment is associated with PTB, and to assess differences by maternal age and nativity. METHODS:D...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Auger N,Abrahamowicz M,Park AL,Wynant W

    更新日期:2013-01-01 00:00:00

  • Depressive symptoms have an independent, gradient risk for coronary heart disease incidence in a random, population-based sample.

    abstract:PURPOSE:Depression is a risk factor for incident coronary heart disease (CHD), and predicts poor prognosis for patients post-myocardial infarction (MI). Few population-based, prospective studies have tested a gradient risk for depressive symptoms on CHD incidence. METHODS:The sample (n=1302) was derived from the Nova ...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Rowan PJ,Haas D,Campbell JA,Maclean DR,Davidson KW

    更新日期:2005-04-01 00:00:00

  • Population-wide sodium reduction: the bumpy road from evidence to policy.

    abstract::Elevated blood pressure is a highly prevalent condition that is etiologically related to coronary heart disease and stroke, two of the leading causes of morbidity and mortality throughout the world. Excess salt (sodium chloride) intake is a major determinant of elevated blood pressure. In this article, we discuss the ...

    journal_title:Annals of epidemiology

    pub_type: 历史文章,杂志文章


    authors: Appel LJ,Angell SY,Cobb LK,Limper HM,Nelson DE,Samet JM,Brownson RC

    更新日期:2012-06-01 00:00:00

  • Racial and ethnic disparities in severe maternal morbidity prevalence and trends.

    abstract:PURPOSE:Racial/ethnic disparities in severe maternal morbidity (SMM) are substantial, but little is known about whether these disparities are changing over time or the role of maternal and obstetric factors. METHODS:We examined disparities in SMM prevalence and trends using linked birth certificate and delivery discha...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Leonard SA,Main EK,Scott KA,Profit J,Carmichael SL

    更新日期:2019-05-01 00:00:00

  • Development of the multiple metabolic syndrome in the ARIC cohort: joint contribution of insulin, BMI, and WHR. Atherosclerosis risk in communities.

    abstract:PURPOSE:The natural history of the multiple metabolic syndrome (MMS) and its predictors has rarely been addressed in population samples. This study evaluated the predictive role of fasting serum insulin, body mass index (BMI), and waist-to-hip ratio (WHR) on the development of incident MMS components (diabetes, hyperte...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Liese AD,Mayer-Davis EJ,Tyroler HA,Davis CE,Keil U,Duncan BB,Heiss G

    更新日期:1997-08-01 00:00:00

  • The potential for Simpson's paradox in drug utilization studies.

    abstract:PURPOSE:Simpson's paradox is a type of severe confounding wherein a confounding variable changes the direction of an association. METHODS:This article demonstrates Simpson's paradox with three cohorts of naproxen users (new users, chronic users, and combined users) who were compared on the age/sex distribution of furt...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Neutel CI

    更新日期:1997-10-01 00:00:00

  • Strong upward neighborhood mobility and preterm birth: a matched-sibling design approach.

    abstract:PURPOSE:Much cross-sectional work reports an association between neighborhood disadvantage and adverse birth outcomes. Limitations of this work include that mothers with pre-existing unmeasured morbidity may "select" into, or out of, certain neighborhoods. This selection issue remains a key rival explanation for work c...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Bruckner TA,Kane JB,Gailey S

    更新日期:2019-08-01 00:00:00

  • In search of susceptibility genes for type 2 diabetes in West Africa: the design and results of the first phase of the AADM study.

    abstract:PURPOSE:The purpose of this study is to map type 2 diabetes susceptibility genes in West African ancestral populations of African-Americans, through an international collaboration between West African and US investigators. DESIGN AND METHODS:Affected sib-pairs (ASP) along with unaffected spouse controls are being enro...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Rotimi CN,Dunston GM,Berg K,Akinsete O,Amoah A,Owusu S,Acheampong J,Boateng K,Oli J,Okafor G,Onyenekwe B,Osotimehin B,Abbiyesuku F,Johnson T,Fasanmade O,Furbert-Harris P,Kittles R,Vekich M,Adegoke O,Bonney G,Colli

    更新日期:2001-01-01 00:00:00

  • Job exposures as correlates of recovery in population-based rehabilitation intervention for work-related low back disorders.

    abstract::PURPOSE: Evaluating the impact of population-based rehabilitation interventions for work-related low back disorders (WR-LBD) requires job exposure factors to be considered as time-varying covariates. The role of job factors in recovery has not been well-established as most studies are based upon clinic samples, not wo...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Oleske D,Lavender S,Andersson G,Hahn J,Zold-Kilbourn P,Allen-Toole C,Laskowski J

    更新日期:2000-10-01 00:00:00

  • Disparities in cervical cancer survival among Asian-American women.

    abstract:PURPOSE:We compared overall survival and influencing factors between Asian-American women as a whole and by subgroup with white women with cervical cancer. METHODS:Cervical cancer data were from the Surveillance, Epidemiology, and End Results registry; socioeconomic information was from the Area Health Resource File. ...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Nghiem VT,Davies KR,Chan W,Mulla ZD,Cantor SB

    更新日期:2016-01-01 00:00:00

  • Blood lipids in Greek adolescents and their relation to diet, obesity, and socioeconomic factors.

    abstract::A study of blood lipid levels in adolescent students in rural and urban areas of Greece was undertaken. Blood samples were drawn from 307 adolescents aged 12 to 18 years attending two rural and two urban high schools of different socioeconomic level (urban/lower, urban/higher). Obesity among adolescents had statistica...

    journal_title:Annals of epidemiology

    pub_type: 杂志文章


    authors: Petridou E,Malamou H,Doxiadis S,Pantelakis S,Kanellopoulou G,Toupadaki N,Trichopoulou A,Flytzani V,Trichopoulos D

    更新日期:1995-07-01 00:00:00