Abstract:
PURPOSE:To examine the association betweenantineoplastic drug (AD) handling and risk of miscarriage. METHODS:Nurses' Health Study-3 participants self-reported AD administration and engineering controls (ECs) and personal protective equipment (PPE) use at baseline. We estimated the hazard ratio (HR) of miscarriage in relation to baseline AD handling using multivariable Cox proportional regression. RESULTS:Overall, 2440 nurses reported 3327 pregnancies, with 550 (17%) ended in miscarriages. Twelve percent of nurses self-reported currently handling AD and 28% previously handling AD. Compared with nurses who never handled AD, nurses who handled AD at baseline had an adjusted HR of miscarriage of 1.26 (95% confidence interval [CI], 0.97-1.64). This association was stronger after 12-weeks gestation (HR=2.39 [95% CI, 1.13-5.07]). Nurses who did not always use gloves had HR of 1.51 (95% CI, 0.91-2.51) compared with 1.19 (95% CI, 0.89-1.60) for those always using gloves; nurses who did not always use gowns had HR of 1.32 (95% CI, 0.95-1.83) compared with 1.19 (95% CI, 0.81-1.75) for nurses always using gowns. CONCLUSIONS:We observed a suggestive association between AD handling and miscarriage, particularly among nurses who did not consistently use PPE and EC with stronger associations for second trimester losses.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Nassan FL,Chavarro JE,Johnson CY,Boiano JM,Rocheleau CM,Rich-Edwards JW,Lawson CCdoi
10.1016/j.annepidem.2020.09.003subject
Has Abstractpub_date
2021-01-01 00:00:00pages
95-102.e2eissn
1047-2797issn
1873-2585pii
S1047-2797(20)30348-3journal_volume
53pub_type
杂志文章abstract:PURPOSE:Young men who have sex with men (YMSM) are likely to experience depression due to enacted and internalized stigma. Whether enacted stigma impacts depression through internalized stigma and whether resilience moderates the negative effect are unclear. This study aims to examine a moderated mediation model to exp...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2021.01.001
更新日期:2021-01-07 00:00:00
abstract::The association between premature menopause and low back pain was examined among 5325 women surveyed in the second National Health and Nutrition Examination survey. Nearly 49% of the women were postmenopausal. In a multiple logistic regression model that included age, postmenopausal women were approximately twice as l...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(94)90077-9
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:To examine associations between macronutrient and total energy intakes with lower urinary tract symptoms (LUTS) in women. METHODS:Cross-sectional analysis of 2060 women aged 30-79 years in the population-based Boston Area Community Health Survey (2002-2005). Data were collected by validated food frequency ques...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.11.014
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To examine whether smoking during first pregnancy, a time of potential vulnerability to tobacco mutagens, is associated with breast cancer. METHODS:We conducted a nested case-control study within a cohort of Washington State residents with first deliveries during 1984-1999, identified in birth and fetal death ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.09.004
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:The aim of this work was to evaluate whether the number of components influences the diagnostic accuracy of a diet quality index and whether this association is affected by the intercorrelation structure of components and by the association of components with an outcome (intracorrelation). METHODS:Simulated da...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2009.03.019
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:Understanding how to mitigate the present black-white obesity disparity in the United States is a complex issue, stemming from a multitude of intertwined causes. An appropriate but underused approach to guiding policy approaches to this problem is to account for this complexity using simulation modeling. METHO...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.05.012
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To evaluate the factors associated with receiving cutaneous injection-related infection (CIRI) care among a representative cohort of supervised injecting facility (SIF) users. METHODS:Data were collected biannually as part of a prospective cohort, the Scientific Evaluation of Supervised Injection study. Kaplan...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2009.03.007
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:Burden of disease (BoD) assessments typically rely on national-level incidence rates for the health outcomes of interest. The impact of using a constant national-level incidence rate, versus a more granular spatially varying rate, remains unknown and understudied in the literature. There has been an increasing ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.08.063
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:Information on the epidemiology of end-stage liver disease (ESLD) in US correctional populations is limited. We examined the prevalence, mortality and clinical characteristics of ESLD in the nation's second largest state prison system. METHODS:We collected and analyzed medical and demographic data from 370,...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.04.005
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:The purpose of this study is to determine whether demographics, health, and job factors influence continued participation of employed persons in a longitudinal intervention study of tertiary prevention for work-related low-back disorders (WR-LBDs). METHODS:Four hundred fifty-four actively employed persons had ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.07.003
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Few studies have examined methods of contraception, beyond oral contraceptives (OCs) and tubal ligation, in relation to ovarian cancer risk. METHODS:Nine hundred two cases with incident ovarian/peritoneal/tubal cancer were compared with 1800 population-based control subjects. Women self-reported all methods of...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.10.002
更新日期:2011-03-01 00:00:00
abstract::Some of the readjustment problems of Vietnam veterans have been attributed to posttraumatic stress disorder (PTSD). This case-control study compared demographic and military characteristics of 374 Vietnam veterans who had PTSD with 373 healthy Vietnam veterans. Veterans were chosen from the Agent Orange Registry, a De...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(91)90022-5
更新日期:1991-11-01 00:00:00
abstract::PURPOSE: Geographic Information Systems (GIS) are useful tools for identifying populations with potential exposure to environmental contaminants. Using a GIS, features of the local environment around an individual's home, work, or school can be described. We present two examples illustrating methods and issues in iden...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(00)00152-6
更新日期:2000-10-01 00:00:00
abstract:PURPOSE:We aimed to investigate the prevalence and prognostic impact of tumor mesenchymal epithelial transition factor (MET) expression in stage IV gastric cancers in a real-world clinical setting because existing evidence is sparse. METHODS:The study included archived cancer specimens from 103 stage IV gastric cancer...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2016.05.002
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:Maternal marriage is protective against preterm birth (PTB), whereas advanced maternal age is associated with increased PTB risk. Because relations between social factors and health may vary during the life course, we assessed how the relation between marital status and PTB risk may change with maternal age. M...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2012.01.002
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:To examine the longitudinal associations between exposure to violence with a weapon during the past year among adolescents and hypertension during adulthood, including the extent to which adult cardiovascular risk factors mediated the association. METHODS:Secondary analysis of the National Longitudinal Stud...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2013.12.004
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To provide a synthesis of current approaches to the discovery of genes associated with complex human diseases by examining the joint potential of traditional epidemiologic methods and current molecular techniques for gene discovery. METHODS:A discussion of optimal approaches for defining complex disease phenot...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/s1047-2797(98)00064-7
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:We sought to examine the importance of childhood circumstances, adult socioeconomic status, and material circumstances to physical and mental functioning among middle-aged women and men. METHODS:The data were collected among the employees of the City of Helsinki by mailed questionnaires from 2000 to 2002 (7148...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.11.003
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:Life expectancy is used to measure population health, but large differences in mortality can be masked even when there is no life expectancy gap. We demonstrate how Arriaga's decomposition method can be used to assess inequality in mortality between populations with near equal life expectancy. METHODS:We calcu...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.05.006
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To examine mental health indicators, in aggregate and stratified by sex, among a population-based sample of U.S. military veterans. METHODS:Data are from veteran who completed the Veterans Health Module (VHM) of the 2011 and 2012 Behavioral Risk Factor Surveillance System (n = 10,406). VHM items included lifet...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2016.06.009
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Preterm birth is associated with gastric acid-related disorders in infancy, but no investigators have examined this association beyond early childhood. We used antisecretory medication data to explore whether preterm birth is associated with gastric acid-related disorders in young adulthood. METHODS:We conduct...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2012.02.006
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:Research examining the association between crime and health outcomes has been hampered by a lack of reliable small-area (e.g., census tract or census block group) crime data. Our objective is to assess the accuracy of synthetically estimated crime indices for use in health research by using preterm birth as a c...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.11.008
更新日期:2020-12-05 00:00:00
abstract:PURPOSE:Continuous monitoring of health determinants in populations is necessary to predict future disease burdens. The objective of this study was to assess the prevalences of major risk factors for lifestyle diseases for 8 years (1993 to 2000) in representative samples of the general population. METHODS:Independent ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(03)00055-3
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:Gastroesophageal reflux disease is an important and increasingly common condition. Both overweight and high fat food consumption have been implicated as causes of reflux disease. We examined the relationship of overweight, high dietary fat intake, and other factors with reflux disease hospitalization. METHODS:...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(99)00020-4
更新日期:1999-10-01 00:00:00
abstract:PURPOSE:The case-crossover design was originally intended to study brief exposures with immediate and transient effects, and acute outcomes with abrupt onsets. We investigated whether case-crossover methods can be used to study prolonged exposures and insidious outcomes. METHODS:We conducted a case-crossover study of ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2003.09.012
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To quantify the impact of ignoring misclassification of a response variable and measurement error in a covariate on statistical power, and to develop software for sample size and power analysis that accounts for these flaws in epidemiologic data. METHODS:A Monte Carlo simulation-based procedure is developed to...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.03.012
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:Interactions between bacterial vaginosis (BV) and inflammatory sexually transmitted infections, such as gonorrhea and chlamydial infection, are not well understood. Furthermore, evidence regarding the sexual transmission of BV is equivocal. METHODS:We assessed associations between incident BV and incidences of...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.11.005
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Estimates of mammography utilization vary considerably, depending on the data source. Among women aged 65 years and older, recent estimates of annual mammography derived from the 1992 National Health Interview Survey (NHIS) were 50% higher than estimates from Medicare claims. We investigated possible reasons fo...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(98)00010-6
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:Socioeconomic status (SES) as a risk factor for mortality in type 1 diabetes (T1D) has not been adequately studied prospectively. METHODS:Complete clinical and SES (income, education, occupation) data were available for 317 T1D participants in the Pittsburgh Epidemiology of Diabetes Complications Study within ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.02.011
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:The metabolic syndrome (MS) is conceived as a cluster of disorders that increase risk for coronary heart disease and type 2 diabetes. Studies examining its structure primarily have used an exploratory factor analytic technique, but yielded discrepant results. There also is a lack of research that investigates w...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2005.06.049
更新日期:2006-02-01 00:00:00