Abstract:
:Monoclonal antibodies against ryanodine receptor (5C3) and calcium ATPase (D12) of skeletal muscle sarcoplasmic reticulum were used in an immunoelectron microscopic study of cerebellar Purkinje cells and neurons of the hypoglossal and dorsal motor nuclei of the vagus (DMV) from rat and guinea-pig. All neurones were labelled with D12 and all, except rat DMV, labelled with 5C3. Most labelling was on smooth endoplasmic reticulum within 500 nm of the plasmalemma where Ca(2+)-activated Ca2+ release would rapidly increase cytosolic calcium following a small Ca2+ influx across the plasmalemma.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Sah P,Dulhunty A,Junankar P,Stanhope Cdoi
10.1016/0304-3940(94)90471-5subject
Has Abstractpub_date
1994-01-31 00:00:00pages
143-8issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(94)90471-5journal_volume
166pub_type
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journal_title:Neuroscience letters
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更新日期:2012-05-02 00:00:00
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更新日期:1991-01-02 00:00:00
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