Imaging functional activation of the auditory cortex during focal repetitive transcranial magnetic stimulation of the primary motor cortex in normal subjects.

abstract：:The vitamin nicotinamide can protect against oxidative stress-induced apoptosis in the brain when used as a precursor for nicotinamide adenine dinucleotide (NAD+). The intracerebroventricular administration of tertiary-butylhydroperoxide (t-buOOH) to mice was used to simulate physiologic oxidative stress and apoptosis...

journal_title：Neuroscience letters

authors： Klaidman LK,Mukherjee SK,Hutchin TP,Adams JD

更新日期：1996-03-08 00:00:00

abstract：:Bis(7)-tacrine [bis(7)-tetrahydroaminacrine] acts as an AChE inhibitor and also exerts modulatory effects on many ligand-gated ion channels and voltage-gated Ca(2+) and K(+) channels. It has been reported previously that tacrine and some other AChE inhibitors suppressed I(K(A)) in central and peripheral neurons. The p...

journal_title：Neuroscience letters

authors： Nie H,Yu WJ,Li XY,Yuan CH,Pang YP,Li CY,Han YF,Li ZW

更新日期：2007-01-29 00:00:00

abstract：:For the fast and accurate cognition of external information, the human brain seems to integrate information from multi-sensory modalities. We used positron emission tomography (PET) to identify the brain areas related to auditory-visual speech perception. We measured the regional cerebral blood flow (rCBF) of young, n...

journal_title：Neuroscience letters

authors： Kawase T,Yamaguchi K,Ogawa T,Suzuki K,Suzuki M,Itoh M,Kobayashi T,Fujii T

更新日期：2005-07-15 00:00:00

abstract：:Evidence, based on voltage-clamp and current-clamp recording, is presented for endogenous receptors for vasoactive intestinal polypeptide (VIP) on the cell membrane of the Xenopus oocyte. At normal resting potential a hyperpolarisation is produced by VIP, associated with an increase in K+ conductance. The response is ...

journal_title：Neuroscience letters

authors： Reale V,Ashford ML,Barnard EA

更新日期：1987-12-16 00:00:00

abstract：:A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. A 24 h exposure of three different NO donors, 3-morpholinosydnonimine, S-nitroso-N-acetyl-penicillamine, and S-nitrosoglutathione, induced apoptosis as indicated by follo...

journal_title：Neuroscience letters

authors： Palluy O,Rigaud M

更新日期：1996-04-12 00:00:00

abstract：:Vascular cognitive impairment (VCI) is the second most common cause of dementia after Alzheimer's disease, and the cognitive impairment is one of the common effects of VCI. Unfortunately, it lacks effective therapeutic treatments at present. In our previous study, environmental enrichment (EE), as an early interventio...

journal_title：Neuroscience letters

authors： Xu L,Qu C,Qu C,Shen J,Song H,Li Y,Li T,Zheng J,Zhang J

更新日期：2020-11-20 00:00:00

abstract：:Nerve growth factor (NGF) was injected in the brain of neonatal rats. In eleven of thirty-one rats that received 1 microgram of mouse NGF (2.5S form) on postnatal day 3, NGF receptor-like immunoreactivity was found in the preoptic area (POA) and hypothalamus until 12 days after birth. However, no immunoreactivity was ...

journal_title：Neuroscience letters

authors： Nishizuka M,Arai Y

更新日期：1992-04-27 00:00:00

abstract：:Noradrenergic fibers from the locus ceruleus were identified in close proximity to brain microvessels, and adrenoceptors exist in isolated brain capillaries. Yet, proof of innervation of brain microvessels by locus ceruleus remains elusive. We now demonstrate increased density of beta-adrenoceptors by pindolol binding...

journal_title：Neuroscience letters

authors： Kalaria RN,Stockmeier CA,Harik SI

更新日期：1989-02-13 00:00:00

abstract：:Rat neocortical slices maintained in Mg2(+)-free Krebs medium developed spontaneous paroxysmal discharges which were attenuated or suppressed by the gamma-aminobutyric acid-B (GABAB) receptor agonist baclofen, occasionally accompanied by a slight hyperpolarisation, and antagonised by the specific GABAB-receptor antago...

journal_title：Neuroscience letters

authors： Ong J,Kerr DI,Johnston GA,Hall RG

更新日期：1990-02-05 00:00:00

abstract：:In the neuritic plaques of Alzheimer's disease, abnormal neuritic processes cluster around a core of beta-amyloid protein. Previous data have shown that beta 1-28, a peptide homologous to the first 28 amino acid residues of beta-amyloid protein, enhanced survival without affecting neuritic extension or branching in cu...

journal_title：Neuroscience letters

authors： Whitson JS,Glabe CG,Shintani E,Abcar A,Cotman CW

更新日期：1990-03-14 00:00:00

abstract：:After short periods of intense sympathetic activation, the action of the vagus nerve on heart rate is inhibited for periods of many minutes to several hours. This effect is not abolished by effective blockade of alpha- or beta-adrenoceptors and is not duplicated by administration of noradrenaline or isoprenaline. A si...

journal_title：Neuroscience letters

authors： Potter EK

更新日期：1985-03-15 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:To elucidate whether high serum lipid peroxidation rates may increase the risk of developing Parkinson's disease (PD), we assessed serum levels of malondialdehyde (MDA), an intermediate in lipid peroxidation processes, in 37 PD patients, with their spouses as the control group. Serum MDA levels did not differ signific...

journal_title：Neuroscience letters

authors： Molina JA,Jiménez-Jiménez FJ,Fernandez-Calle P,Lalinde L,Tenias JM,Pondal M,Vazquez A,Codoceo R

更新日期：1992-03-02 00:00:00

abstract：:Deimination is a post-translational modification of proteins in which selected arginine amino acids are enzymatically converted to citrullines. Using dual-color immunofluorescence, the present study is the first to examine the frontal cortex of patients with Alzheimer's disease (AD) versus age-matched controls with an...

journal_title：Neuroscience letters

authors： Nicholas AP

更新日期：2013-06-17 00:00:00

abstract：:The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, s...

journal_title：Neuroscience letters

authors： Evans HF,Huntley GW,Morrison JH,Shine J,Paxinos G

更新日期：1992-11-09 00:00:00

abstract：:This article has been withdrawn at the request of the Editor-in-Chief. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Neuroscience letters

authors： Sun Y,Zhou M,Wang D,Chen F,Wang Q,Han X,Cheng W

更新日期：2020-06-24 00:00:00

abstract：:Amyloid beta-protein, the major constituent of Alzheimer's disease (AD) brain amyloid deposits, is encoded by several alternatively spliced amyloid precursor protein (APP) mRNAs. The well-established associated in Down's syndrome (DS) between APP overproduction and premature development of AD, as well as the recent de...

journal_title：Neuroscience letters

authors： Ledoux S,Bergeron C,Nalbantoglu J,Gauthier S,Cashman NR

更新日期：1995-06-30 00:00:00

abstract：:Recent studies have shown an association between Parkinson disease (PD) and mutations in the gene encoding the lysosomal enzyme glucocerebrosidase (GBA), which is deficient in patients with Gaucher disease. In Asian populations, 2 mutational analysis studies have been performed in all exons of GBA; one study in a Japa...

journal_title：Neuroscience letters

authors： Choi JM,Kim WC,Lyoo CH,Kang SY,Lee PH,Baik JS,Koh SB,Ma HI,Sohn YH,Lee MS,Kim YJ

更新日期：2012-04-11 00:00:00

abstract：:Alpha-synuclein has been implicated in the pathology of certain neurodegenerative diseases, including Parkinson disease (PD) and dementia with Lewy bodies (LBs). Overexpression of human alpha-synuclein in neuronal cells reduces cell viability, but the precise cellular and molecular mechanisms remain poorly understood....

journal_title：Neuroscience letters

authors： Sung JY,Lee HJ,Jeong EI,Oh Y,Park J,Kang KS,Chung KC

更新日期：2007-04-18 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:Insulin-like growth factor-1 (IGF1) and its active peptide (1-3)IGF1 modulate brain growth and plasticity and are candidate molecules for treatment of brain disorders. IGF1 N-terminal portion is naturally cleaved to generate the tri-peptide (1-3)IGF1 (glycine-praline-glutamate). IGF1 and (1-3)IGF have been proposed as...

journal_title：Neuroscience letters

authors： Corvin AP,Molinos I,Little G,Donohoe G,Gill M,Morris DW,Tropea D

更新日期：2012-06-27 00:00:00

abstract：:The brain and nasal region of a fetal (124 days) female rhesus macaque (Macaca mulatta) were fixed in situ, decalcified, sectioned and treated for the immunocytochemical demonstration of LHRH. Immunoreactive neurons and fibers were found in expected sites and also in sites not reported to date in primates: there was a...

journal_title：Neuroscience letters

authors： Witkin JW

更新日期：1987-08-18 00:00:00

abstract：:Mild cognitive impairment (MCI) is a nosological entity proposed as an intermediate state between normal aging and dementia. MCI seems to represent an early stage of Alzheimer's disease (AD) and there is a great interest in the relationship between MCI and the progression to AD. Some studies have demonstrated an accum...

journal_title：Neuroscience letters

authors： Padurariu M,Ciobica A,Hritcu L,Stoica B,Bild W,Stefanescu C

更新日期：2010-01-18 00:00:00

abstract：:The dentate gyrus of the hippocampus is one of few regions in the adult mammalian brain characterized by ongoing neurogenesis. It has been demonstrated that Noggin antagonizes bone morphogenetic protein-4 (BMP4) to create a niche for subventricular zone neurogenesis. We previously demonstrated that Noggin and BMP4 sho...

journal_title：Neuroscience letters

authors： Fan XT,Xu HW,Cai WQ,Yang H,Liu S

更新日期：2004-08-05 00:00:00

abstract：:Retrograde axonal transport and fluorescent retrograde labelling of neurons were investigated in a crustacean motor system. A fluorescent tracer (Granular blue) was injected into an antennal muscle of rock lobster in order to identify the motor neurons innervating it. After an appropriate post-injection survival time,...

journal_title：Neuroscience letters

authors： Rossi-Durand C,Sorensen KE

更新日期：1985-04-09 00:00:00

abstract：:We investigated the relation between visual feedback and the degree of structure versus randomness in the variability of single-digit, isometric force output. Participants were instructed to maintain a constant level of force during the presence or absence of visual feedback about force output. The structure of force ...

journal_title：Neuroscience letters

authors： Athreya DN,Van Orden G,Riley MA

更新日期：2012-03-28 00:00:00

abstract：:Approximately 8.5% of the unmyelinated and 2.5% of the myelinated primary afferent axons in lumbar dorsal roots of normal rats are immunostained for glutamate. Thus unmyelinated fibers are the predominantly immunostained population under the conditions of our experiments. The mean size of the unmyelinated fibers is gr...

journal_title：Neuroscience letters

authors： Westlund KN,McNeill DL,Coggeshall RE

更新日期：1989-01-02 00:00:00

abstract：:The cellular prion protein (PrP(C)) is crucial for the development of transmissible spongiform encephalopathies (TSEs), where the pathogenic scrapie isoform (PrP(Sc)) of the same protein, is considered to be the principal or sole infectious agent. Here, we report findings on PrP(C) expression in the rat forebrain, usi...

journal_title：Neuroscience letters

authors： Verghese-Nikolakaki S,Michaloudi H,Polymenidou M,Groschup MH,Papadopoulos GC,Sklaviadis T

更新日期：1999-09-03 00:00:00

abstract：:The distribution of premotor neurons projecting to motor nuclei of both the VIIth (VII) and XIIth (XII) nerves was examined in the pontomedullary reticular formation (RF) of the rat by using retrograde double labeling. After injection of two different tracers in the VII and the XII, most of the double labeled neurons ...

journal_title：Neuroscience letters

authors： Dauvergne C,Pinganaud G,Buisseret P,Buisseret-Delmas C,Zerari-Mailly F

更新日期：2001-09-28 00:00:00

abstract：:Compared to other M(1) muscarinic acetylcholine receptor (M(1) mAChR) agonists, xanomeline demonstrates both reversible and persistent modes of binding to the receptor. In our study, we investigated the long-term consequences of brief incubation of Chinese hamster ovary cells expressing M(1) mAChR (M(1)-CHO) with low ...

journal_title：Neuroscience letters

authors： De Lorme KC,Sikorski KL,Grant MK,El-Fakahany EE

更新日期：2006-12-13 00:00:00