Abstract:
:Microrecording of single unit response to contact heat-evoked potential (CHEP) were performed in right ventral posterior lateral (VPL) thalamus during deep brain stimulation (DBS) surgery in a patient with chronic neurogenic pain. In our patient, neurons (n = 10) recorded in the ventral thalamus fired at a higher rate of 40 Hz compared to neurons recorded in Parkinsonian patients (24 Hz). Contact heat was applied by a fast heating and cooling probe of 5 cm2 area on the dermatome C6 territory of the left hand. One out of four thalamic cells located in the VPL responded repetitively 325 ms after the peak temperature was reached with a burst of action potential, suggesting A-delta fibre activation. This observation supports the use of CHEP for mapping nociceptive neurons location during DBS surgery for intractable pain.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Pralong E,Pollo C,Bloch J,Villemure JG,Daniel RT,Tétreault MH,Debatisse Ddoi
10.1016/j.neulet.2004.06.024keywords:
subject
Has Abstractpub_date
2004-09-09 00:00:00pages
332-5issue
3eissn
0304-3940issn
1872-7972pii
S0304394004007591journal_volume
367pub_type
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