Cortical neuronal ensembles driven by dorsal horn spinal neurones with spontaneous activity in the cat.

Abstract:

:Simultaneous recordings of cortical activity, recorded as the cortical local field potential (CLFP) in the contralateral posterior sigmoid gyrus, and the spinal activity, recorded as the cord dorsum potential (CDP) of the L6 lumbar segment, were made in the anaesthetized cat. The electrodes were positioned in somatosensory regions where the largest spontaneous negative CLFPs and CDPs were recorded. We found that spontaneous negative CLFPs were preceded by spontaneous negative CDPs with a mean latency of 14.4+/-3.5 ms. Amplitude of these spontaneous negative CLFPs was abolished after section of the dorsal columns and ipsilateral dorsolateral funiculus. It is concluded that the neurones of the primary somatosensory cortex can be driven by dorsal horn spinal neurones producing the spontaneous negative CDPs. This suggests very strongly that spontaneous neuronal activity in somatosensory regions of the brain is generated not only by ongoing activity of neurones located at supraspinal sites, but also by ongoing activity of spinal neurones.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Manjarrez E,Rojas-Piloni G,Vazquez D,Flores A

doi

10.1016/s0304-3940(01)02497-1

keywords:

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

145-8

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304394001024971

journal_volume

318

pub_type

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