Abstract:
:A Monte Carlo model is presented to study details of the energy deposition inside tracks of heavy charged particles in water vapor. The input data for most of the calculations based on the binary encounter approximation are double-differential cross sections for electron emission after heavy-ion impact. The paths of the liberated electrons are simulated, taking into account elastic scattering, ionization, and excitation. Each basic interaction of an electron or heavy ion is treated individually. Radial dose distributions and specific energy deposition are calculated for projectiles from protons to uranium in the energy range from one to several hundred mega-electron volts per unified atomic mass unit. Good agreement with measurements in tissue-equivalent gas and propane is obtained for light and medium-heavy projectiles, whereas for heavy projectiles such as uranium, deviations around a factor of 2-3 are observed.
journal_name
Radiat Environ Biophysjournal_title
Radiation and environmental biophysicsauthors
Krämer M,Kraft Gdoi
10.1007/BF01219334subject
Has Abstractpub_date
1994-01-01 00:00:00pages
91-109issue
2eissn
0301-634Xissn
1432-2099journal_volume
33pub_type
杂志文章,评审abstract::About a century ago, Conrad Röentgen discovered X-rays, and Henri Becquerel discovered a new phenomenon, which Marie and Pierre Curie later coined as radio-activity. Since their seminal work, we have learned much about the physical properties of radiation and its effects on living matter. Alas, the more we discover, t...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章,评审
doi:10.1007/s00411-007-0146-8
更新日期:2008-02-01 00:00:00
abstract::Four different thiol reagents: p-chloromercuribenzoic acid (pCMB), mercuric chloride (HgCl2), N-ethylmaleimide (NEM), and 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) were employed as agents modifying the transport of a hydrophilic and hydrophobic non-electrolyte spin labels: 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-o...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01323760
更新日期:1983-01-01 00:00:00
abstract::The model of radiocaesium transfer to sheep presented by Galer et al. provides reliable predictions only for sheep of a similar body weight to those used in the development of the model (approximately 30 kg). To extend the applicability of the model, it was necessary to re-parameterise it in terms of activity concentr...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01211238
更新日期:1996-02-01 00:00:00
abstract::Low-dose ionizing radiation (IR) responses remain an unresolved issue in radiation biology and risk assessment. Accurate knowledge of low-dose responses is important for estimation of normal tissue risk in cancer radiotherapy or health risks from occupational or hazard exposure. Cellular responses to low-dose IR appea...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-020-00854-x
更新日期:2020-08-01 00:00:00
abstract::Checkpoints are components of signalling pathways involved in genome stability. We analysed the putative dual functions of Rad17 and Chk1 as checkpoints and in DNA repair using mutant strains of Saccharomyces cerevisiae. Logarithmic populations of the diploid checkpoint-deficient mutants, chk1Delta/chk1Delta and rad17...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-007-0119-y
更新日期:2007-11-01 00:00:00
abstract::In this work, direct DNA damage induced by low-energy electrons (sub-keV) is simulated using a Monte Carlo method. The characteristics of the present simulation are to consider the new mechanism of DNA damage due to dissociative electron attachment (DEA) and to allow determining damage to specific bases (i.e., adenine...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-016-0681-2
更新日期:2017-03-01 00:00:00
abstract::Microcalorimetric experiments on growth and maintenance metabolism of Saccharomyces strains ranging from haploid to hexaploid are described. During growth, the mean dry weight, the mean volume and the maximum heat flux of the cells are nearly linear functions of ploidy. These parameters are correlated with the cell co...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01323624
更新日期:1976-03-30 00:00:00
abstract::Osteosarcoma is the most frequent secondary malignancy following radiotherapy of patients with bilateral retinoblastoma. This suggests that the Rb1 tumour suppressor gene might confer genetic susceptibility towards radiation-induced osteosarcoma. To define the contribution of the Rb1 pathway in the multistep process o...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-010-0339-4
更新日期:2011-03-01 00:00:00
abstract::Testing the limits of survivability in space is the primary focus in astrobiological research. Although a number of previous studies have examined terrestrial life survival in an extraterrestrial environment, only a few have investigated how life systems respond to high doses of alpha cosmic ray, the main component of...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-019-00803-3
更新日期:2019-08-01 00:00:00
abstract::In spite of a well-known relationship between exposure to radiation and increased risk for cancer development, the biological mechanisms involved in radiation-induced carcinogenesis remain poorly documented. Various hypotheses are discussed in this paper. It appears that radiation cannot be directly responsible for th...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章,评审
doi:10.1007/BF01209747
更新日期:1995-11-01 00:00:00
abstract::The biophysical characteristics of heavy ions make them a rational source of radiation for use in radiotherapy of malignant tumours. Prior to radiotherapy treatment, a therapeutic regimen must be precisely defined, and during this stage information on individual patient radiosensitivity would be of very great medical ...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-006-0063-2
更新日期:2006-11-01 00:00:00
abstract::Blue (F450) and green (F530) leaf fluorescence were studied together with the red chlorophyll fluorescence (emission maxima F690 and F735) during light-induced chlorophyll fluorescence induction kinetics (Kautsky effect) in predarkened leaves of wheat (Triticum aestivum L.) and soybean (Glycine max L.). The intensity ...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01225923
更新日期:1993-01-01 00:00:00
abstract::The probability of the formation of ionization clusters by primary alpha-particles at 5.4 MeV in nanometric volumes of propane was studied experimentally and by Monte Carlo simulation, as a function of the distance between the center line of the particle beam and the center of the target volume. The volumes were of cy...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-002-0171-6
更新日期:2002-12-01 00:00:00
abstract::The aim of this work was to define the possible occurrence of hematological changes during the course of a chronic ingestion of (137)Cs. A mouse model was used, with ingestion through drinking water with a cesium concentration of 20 kBq l(-1). Ingestion started in parent animals before mating, and (137)Cs intake and i...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-010-0267-3
更新日期:2010-05-01 00:00:00
abstract::Heavy charged particle therapy, started at research institutes three decades ago, is now on the verge of entering a clinical phase. This phase has resulted from the evolution and development of various beam delivery systems and techniques with existing research accelerators and with newly built accelerators. For the f...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章,评审
doi:10.1007/BF01214829
更新日期:1992-01-01 00:00:00
abstract::The effects of single pulses and multiple pulses of 7 MV electrons on micronuclei (MN) induction in cytokinesis-blocked human peripheral blood lymphocytes (PBLs) were investigated over a wide range of dose rates per pulse (instantaneous dose rate). PBLs were exposed to graded doses of 2, 3, 4, 6, and 8 Gy of single el...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-011-0353-1
更新日期:2011-05-01 00:00:00
abstract::The potential of proton microchannel radiotherapy to reduce radiation effects in the healthy tissue but to keep tumor control the same as in conventional proton therapy is further elucidated. The microchannels spread on their way to the tumor tissue resulting in different fractions of the healthy tissue covered with d...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-015-0600-y
更新日期:2015-08-01 00:00:00
abstract::Non-linear mechanical response of viscoelastic strain responding media to high amplitude stress-strain is examined from a phenomenological point of view and found to lead to results compatible with empirical observations of high intensity ultrasound irradiation of brain, liver, and eye lens tissues. The proposed hyste...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01324230
更新日期:1981-01-01 00:00:00
abstract::Activity catalysing double-strand DNA recombination has been investigated in human tumour cell lines using an in vitro assay in which nuclear extracts from tumour cells are used to catalyse homologous recombination between deletion plasmids. The cell lines investigated showed comparable constitutive levels of recombin...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s004110050056
更新日期:1997-02-01 00:00:00
abstract::For the estimation of radiation doses to organisms, concentration ratios (C ( R )s) of radionuclides are required. In the present study, C(R)s of various elements were obtained as analogues of radionuclides for algae, molluscs, and crustaceans, in eight estuarine areas around Japan. The elements measured were Na, Mg, ...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-010-0317-x
更新日期:2010-11-01 00:00:00
abstract::The hypoxic cytotoxic effect of chlorpromazine towards E. coli B/r was observed to be dependent on temperature of incubation and irradiation. Increasing the temperature of incubation from ambient to 37 degrees C followed by irradiation revealed that the organisms showed radiosensitivity of a magnitude which was two to...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01229816
更新日期:1985-01-01 00:00:00
abstract::This study aimed to evaluate the biological effects of gamma irradiation on zebrafish embryos. Different doses of gamma rays (0.01, 0.05, 0.1, 0.5 and 1 Gy) were used to irradiate zebrafish embryos at three developmental stages (stage 1, 6 h post-fertilization (hpf); stage 2, 12 hpf; stage three, 24 hpf), respectively...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-016-0663-4
更新日期:2016-11-01 00:00:00
abstract::Hematoporphyrin (Hp) solutions were subjected to a wide range high intensity (0.2-10.0 GW/cm2) near-UV laser pulse radiation (lambda exc = 355 nm, pulse duration 30 ps). The formation of stable Hp photoproducts was followed by UV-VIS absorption spectroscopy and liquid-gel column chromatography. As judged by the influe...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01210525
更新日期:1990-01-01 00:00:00
abstract::In this pilot study we compared for the first time the radiation sensitivity of mouse lens epithelial cells (LECs) and mouse lymphocytes. We freshly prepared LECs and lymphocytes and irradiated them with γ-rays ((137)Cs; doses ranging from 0.25 to 2 Gy). DNA damage and repair were evaluated by alkaline comet assay and...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-012-0451-8
更新日期:2013-05-01 00:00:00
abstract::The aim of this study was to detect membrane fluidity modifications in blood lymphocytes that had been exposed to gamma-radiation, at a graded series of depths from the surface to the centre of the membrane bilayer and as a function of cell viability. A time course was performed to verify the contribution of the membr...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s004110100104
更新日期:2001-09-01 00:00:00
abstract::Stem cells surviving radiation injury may carry defects which contribute to long-term effects. The ratio of 125-iododeoxyuridine (IUdR) uptake into spleens of lethally irradiated recipient mice between day 3 and day 5 after cell transfusion revealed reduced proliferative ability (PF) of spleen seeding cells in paralle...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/BF01211733
更新日期:1986-01-01 00:00:00
abstract::The development of biophysical models of chromosome aberration induction has undergone considerable improvements in the past few years. This is mainly due to the development of new experimental techniques, such as fluorescence in situ hybridization (FISH) and premature chromosome condensation (PCC), and to a better kn...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章,评审
doi:10.1007/s004110050132
更新日期:1999-05-01 00:00:00
abstract::To explore possible applications of iodoacetate (IA), a glycolytic inhibitor, in cancer treatment, we screened its cytotoxicity and radioprotective/sensitizing efficacy in three different mammalian cell lines; A549 (human lung carcinoma), MCF7 (human mammary cancer), a non-cancerous CHO (Chinese hamster ovary) cells a...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s00411-017-0699-0
更新日期:2017-08-01 00:00:00
abstract::An extensive programme of experiments on transfer of radionuclides to aquatic species was conducted in the former USSR starting from the early 1950s. Only a few of these studies were made available in the English language literature or taken into account in international reviews of radionuclide behaviour in marine eco...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章,评审
doi:10.1007/s00411-010-0324-y
更新日期:2010-11-01 00:00:00
abstract::137Cs from global fallout of nuclear weapon testings in the 1950s and 1960s was determined in successive layers (0-30 cm) of eight undisturbed grassland soils in Bavaria, Germany. The maximum activity concentration was found in soil layers between 4 and 15 cm below the surface. Using the vertical distribution of the c...
journal_title:Radiation and environmental biophysics
pub_type: 杂志文章
doi:10.1007/s004110050088
更新日期:1998-04-01 00:00:00