Mice immunized by primary vaginal Candida albicans infection develop acquired vaginal mucosal immunity.

abstract：:Legionella pneumophila is a facultative intracellular bacterium which readily grows in cultures of guinea pig and human mononuclear phagocytes. In this report, we demonstrate that the Legionella sp. also grows in thioglycolate-elicited macrophages obtained from A/J mice but not in cells from other mouse strains tested...

journal_title：Infection and immunity

authors： Yamamoto Y,Klein TW,Newton CA,Widen R,Friedman H

更新日期：1988-02-01 00:00:00

abstract：:The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal B-cell activation, which results in nonspecific activation of multiple B-cell clones was analyzed by a hemolysis-in-gel assay designed ...

journal_title：Infection and immunity

authors： Bick PH,Carpenter AB,Holdeman LV,Miller GA,Ranney RR,Palcanis KG,Tew JG

更新日期：1981-10-01 00:00:00

abstract：:The role of the hypothalamus-pituitary-adrenal (HPA) axis in regulating the growth of Mycobacterium avium in Mycobacterium bovis BCG-resistant and -susceptible congenic mice was evaluated. Restraint was used to activate the HPA axis, which resulted in an increase in the level of corticosterone in the plasma. Activatio...

journal_title：Infection and immunity

authors： Brown DH,Sheridan J,Pearl D,Zwilling BS

更新日期：1993-11-01 00:00:00

abstract：:A multigene family of 58- to 60-kDa proteins, which are designated rhoptry-associated protein 1 (RAP-1) and which come from the parasites Babesia bigemina and Babesia bovis, is a target for vaccine development. The presence of multiple gene copies and conserved sequences and epitopes of RAP-1 implies that these protei...

journal_title：Infection and immunity

authors： Rodríguez SD,Palmer GH,McElwain TF,McGuire TC,Ruef BJ,Chitko-McKown MG,Brown WC

更新日期：1996-06-01 00:00:00

abstract：:Pathogenic leptospires have the ability to survive and disseminate to multiple organs after penetrating the host. Several pathogens, including spirochetes, have been shown to express surface proteins that interact with the extracellular matrix (ECM). This adhesin-mediated binding process seems to be a crucial step in ...

journal_title：Infection and immunity

authors： Barbosa AS,Abreu PA,Neves FO,Atzingen MV,Watanabe MM,Vieira ML,Morais ZM,Vasconcellos SA,Nascimento AL

更新日期：2006-11-01 00:00:00

abstract：:CD8+ T cells are essential for protection against mycobacteria, as is clearly demonstrated by the fatal outcome of experimental infection of beta-2 microglobulin knockout mice. However, the mechanisms and antigens (Ags) leading to CD8+ T-cell activation and regulation have been poorly characterized. Here we show that,...

journal_title：Infection and immunity

authors： Denis O,Lozes E,Huygen K

更新日期：1997-02-01 00:00:00

abstract：:The effect of iron concentration during growth on the physicochemical surface properties of the colonial variants of Neisseria gonorrhoeae has been assessed by aqueous two-phase partitioning in a dextran-polyethyleneglycol system containing positively charged trimethylamino-polyethyleneglycol or hydrophobic polyethyle...

journal_title：Infection and immunity

authors： Magnusson KE,Kihlstrom E,Norqvist A,Davies J,Normark S

更新日期：1979-11-01 00:00:00

abstract：:Nonviable Mycobacterium tuberculosis strain Jamaica suspended in oil-droplet emulsions was used to enhance resistance of mice against encephalomyocarditis virus (EMCV). The mycobacteria-injected mice were significantly resistant to 50,000 50% lethal doses of EMCV. Similar concentrations of virus in plasma of normal an...

journal_title：Infection and immunity

authors： Lodmell DL,Ewalt LC

更新日期：1978-12-01 00:00:00

abstract：:Pathogenicity of Rickettsia tsutsugamushi for laboratory mice is known to be influenced by at least three factors: (i) route of inoculation, (ii) antigenic strain, and (iii) natural resistance of the host. By using Karp, Gilliam, and Kato strains of R. tsutsugamushi, we examined the effect of these three pathogenicity...

journal_title：Infection and immunity

authors： Groves MG,Kelly DJ

更新日期：1989-05-01 00:00:00

abstract：:Synthetic oligosaccharides derived from the capsular polysaccharide (PRP) of Haemophilus influenzae type b were conjugated to carrier proteins via a thioether linkage. Conjugates were made of trimeric and tetrameric ribose-ribitol-phosphate and tetanus toxoid or diphtheria toxin. All conjugates elicited anti-PRP antib...

journal_title：Infection and immunity

authors： Peeters CC,Evenberg D,Hoogerhout P,Käyhty H,Saarinen L,van Boeckel CA,van der Marel GA,van Boom JH,Poolman JT

更新日期：1992-05-01 00:00:00

abstract：:Fibronectin binds to Streptococcus pyogenes, and this binding is inhibited by lipoteichoic acid (LTA). Previous studies have shown that LTA can be released from S. pyogenes by treatment with penicillin. Penicillin released LTA from both S. pyogenes and Staphylococcus aureus; however, the binding of fibronectin correla...

journal_title：Infection and immunity

authors： Nealon TJ,Beachey EH,Courtney HS,Simpson WA

更新日期：1986-02-01 00:00:00

abstract：:When immunocompetent mice are inoculated with Borrelia burgdorferi, they develop acute arthritis and carditis that undergo spontaneous regression despite the persistence of infection. Specific T- and/or B-cell immunity appears to be necessary for resolution of disease manifestations. Humoral immune responses to B. bur...

journal_title：Infection and immunity

authors： Bockenstedt LK,Barthold S,Deponte K,Marcantonio N,Kantor FS

更新日期：1993-05-01 00:00:00

abstract：:Accurate diagnosis and early treatment of tuberculosis (TB) and latent TB infection (LTBI) are vital to prevent and control TB. The lack of specific biomarkers hinders these efforts. This study's purpose was to screen immunological markers that discriminate Mycobacterium tuberculosis infection outcomes in a setting wh...

journal_title：Infection and immunity

authors： Teklu T,Kwon K,Wondale B,HaileMariam M,Zewude A,Medhin G,Legesse M,Pieper R,Ameni G

更新日期：2018-03-22 00:00:00

abstract：:Differences in infection kinetics and host response between Burkholderia multivorans and Burkholderia cenocepacia were demonstrated in a pulmonary infection model in BALB/c mice. B. multivorans persisted in the lung, while B. cenocepacia was cleared. Indirect immunofluorescence and electron microscopy of B. multivoran...

journal_title：Infection and immunity

authors： Chu KK,MacDonald KL,Davidson DJ,Speert DP

更新日期：2004-10-01 00:00:00

abstract：:Glucose has previously been shown to increase the in vitro phagocytosis of unopsonized Pseudomonas aeruginosa by freshly explanted murine peritoneal macrophages (PM) and cultivated alveolar macrophages (AM). This study examined the effect of glucose on the same phagocytosis process in human AM in order to determine wh...

journal_title：Infection and immunity

authors： Wong SY,Guerdoud LM,Cantin A,Speert DP

更新日期：1999-01-01 00:00:00

abstract：:A modified version of the Bacteroides fragilis transposon Tn4400, designated Tn4400', enabling rapid isolation and analysis of B. fragilis mutants has been constructed. To identify potential virulence factors, Tn4400'-generated mutants were screened by a new method; this resulted in the isolation of 21 mutant strains ...

journal_title：Infection and immunity

authors： Tang YP,Malamy MH

更新日期：2000-01-01 00:00:00

abstract：:Cells of the laboratory strain 3153A of Candida albicans can be stimulated to undergo high-frequency phenotypic switching by a low dose of UV. We have compared the adhesive properties of cells exhibiting the basic original smooth (o-smooth) phenotype and three switch phenotypes (star, irregular wrinkle, and revertant ...

journal_title：Infection and immunity

authors： Vargas K,Wertz PW,Drake D,Morrow B,Soll DR

更新日期：1994-04-01 00:00:00

abstract：:We compared a cryptococcal culture filtrate antigen referred to as CneF with chemically defined cryptococcal antigen fractions isolated by Cherniak and co-workers by using double immunodiffusion gels, polyacrylamide gel electrophoresis, immunoblots, and footpad reactivity of immunized mice. The three previously descri...

journal_title：Infection and immunity

authors： Murphy JW,Mosley RL,Cherniak R,Reyes GH,Kozel TR,Reiss E

更新日期：1988-02-01 00:00:00

abstract：:The type III secretion system (T3SS) of pathogenic bordetellae employs a self-associating tip complex protein Bsp22. This protein is immunogenic during infections by Bordetella bronchiseptica and could be used as a protective antigen to immunize mice against B. bronchiseptica challenge. Since low-passage clinical isol...

journal_title：Infection and immunity

authors： Villarino Romero R,Bibova I,Cerny O,Vecerek B,Wald T,Benada O,Zavadilova J,Osicka R,Sebo P

更新日期：2013-08-01 00:00:00

abstract：:The macrophage has previously been implicated in contributing to the renal inflammation associated with hemolytic-uremic syndrome (HUS). However, there is currently no in vivo model detailing the contribution of the renal macrophage to the kidney disease associated with HUS. Therefore, renal macrophage recruitment and...

journal_title：Infection and immunity

authors： Keepers TR,Gross LK,Obrig TG

更新日期：2007-03-01 00:00:00

abstract：:Previous studies have demonstrated that animals exposed to Streptococcus pneumoniae while recovering from influenza A virus infection exhibit exacerbated disease symptoms. However, many of the current animal models exploring dual viral and bacterial synergistic exacerbations of respiratory disease have utilized mouse-...

journal_title：Infection and immunity

authors： Speshock JL,Doyon-Reale N,Rabah R,Neely MN,Roberts PC

更新日期：2007-06-01 00:00:00

abstract：:Yersinia enterocolitica is a human pathogen that is ubiquitous in livestock, especially pigs. The bacteria are able to colonize the intestinal tract of a variety of mammalian hosts, but the severity of induced gut-associated diseases (yersiniosis) differs significantly between hosts. To gain more information about the...

journal_title：Infection and immunity

authors： Schaake J,Kronshage M,Uliczka F,Rohde M,Knuuti T,Strauch E,Fruth A,Wos-Oxley M,Dersch P

更新日期：2013-11-01 00:00:00

abstract：:Peptidoglycans of organisms belonging to the strictly anaerobic family Bacteroidaceae were investigated for the presence of lanthionine. Different procedures for the quantitation of lanthionine were compared. Performic acid and peroxide oxidation procedures on 35S-labeled peptidoglycan from Fusobacterium nucleatum Fev...

journal_title：Infection and immunity

authors： Vasstrand EN,Jensen HB,Miron T,Hofstad T

更新日期：1982-04-01 00:00:00

abstract：:Human granulocytic anaplasmosis (HGA) is caused by the obligate intracellular bacterium Anaplasma phagocytophilum. The critical role of gamma interferon (IFN-gamma) for induction of severe inflammatory histopathology, even in the absence of a significant bacterial load, was previously demonstrated in a murine model of...

journal_title：Infection and immunity

authors： Choi KS,Webb T,Oelke M,Scorpio DG,Dumler JS

更新日期：2007-06-01 00:00:00

abstract：:Pyolysin (PLO), the hemolytic exotoxin expressed by Arcanobacterium (Actinomyces) pyogenes, is a member of the thiol-activated cytolysin family of bacterial toxins. Insertional inactivation of the plo gene results in loss of expression of PLO with a concomitant loss in hemolytic activity. The plo mutant, PLO-1, has an...

journal_title：Infection and immunity

authors： Jost BH,Songer JG,Billington SJ

更新日期：1999-04-01 00:00:00

abstract：:Curli are thin, coiled fibers expressed on the surface of Escherichia coli that bind several matrix and plasma proteins such as fibronectin, laminin, plasminogen, tissue plasminogen activator, and H-kininogen. In this work, we examined the interactions between curli-expressing E. coli and human major histocompatibilit...

journal_title：Infection and immunity

authors： Olsén A,Wick MJ,Mörgelin M,Björck L

更新日期：1998-03-01 00:00:00

abstract：:Streptococcal protective antigen (Spa) is a newly described surface protein of group A streptococci that was recently shown to evoke protective antibodies (J. B. Dale, E. Y. Chiang, S. Liu, H. S. Courtney, and D. L. Hasty, J. Clin. Investig. 103:1261--1268, 1999). In this study, we have determined the complete sequenc...

journal_title：Infection and immunity

authors： McLellan DG,Chiang EY,Courtney HS,Hasty DL,Wei SC,Hu MC,Walls MA,Bloom JJ,Dale JB

更新日期：2001-05-01 00:00:00

abstract：:We have reported that P388D1 cell line murine macrophages stimulated with lipopolysaccharide (LPS) from Actinobacillus actinomycetemcomitans release interleukin-1 (IL-1) inhibitor. The IL-1 inhibitor was purified from conditioned media of P388D1 cells stimulated with A. actinomycetemcomitans LPS for 72 h to homogeneit...

journal_title：Infection and immunity

authors： Nishihara T,Ohsaki Y,Ueda N,Saito N,Mundy GR

更新日期：1994-02-01 00:00:00

abstract：:Outer surface protein A (OspA) of the Lyme disease spirochete is primarily produced in the tick vector. OspA, which is a receptor for attaching spirochetes to the tick gut, is down regulated as the spirochetes leave the tick and enter the mammalian host. Although OspA is not a major antigen produced in the mammal, the...

journal_title：Infection and immunity

authors： Strother KO,Hodzic E,Barthold SW,de Silva AM

更新日期：2007-06-01 00:00:00

abstract：:The purified recombinant V antigen from Yersinia pestis, expressed in Escherichia coli and adsorbed to aluminum hydroxide, an adjuvant approved for human use, was used to immunize outbred Hsd:ND4 mice subcutaneously. Immunization protected mice from lethal bubonic and pneumonic plague caused by CO92, a wild-type F1+ s...

journal_title：Infection and immunity

authors： Anderson GW Jr,Leary SE,Williamson ED,Titball RW,Welkos SL,Worsham PL,Friedlander AM

更新日期：1996-11-01 00:00:00