Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study.

abstract：OBJECTIVE:Cerebral ischemic stroke (IS) threatens the daily life of individuals, with high mortality. Emerging studies have deciphered the independent roles of the long non-coding RNA growth-arrest-specific transcript 5 (GAS5), microRNA (miR)-455-5p and phosphatase and tensin homolog (PTEN) in IS, but the understanding...

journal_title：Brain research bulletin

authors： Wu R,Yun Q,Zhang J,Bao J

更新日期：2021-02-01 00:00:00

abstract：:The susceptibility of the developing brain to hypoxia should depend on the lipid composition of the brain cell membrane; the rate of lipid peroxidation; the presence of antioxidant defenses; and the development and modulation of the excitatory neurotransmitter receptors such as the N-methyl-D-aspartate (NMDA) receptor...

journal_title：Brain research bulletin

authors： Mishra OP,Delivoria-Papadopoulos M

更新日期：1999-02-01 00:00:00

abstract：:Emerging evidence suggests that sleep deprivation (SD) is a public health epidemic and increase the risk of Alzheimer's disease (AD) progression. However, the underlying mechanisms remain to be fully investigated. In this study, we investigate the impact of 72 h SD on the prefrontal cortex (PFC) of 3∼4-months-old APP/...

journal_title：Brain research bulletin

authors： Tabassum S,Misrani A,Tabassum S,Ahmed A,Yang L,Long C

更新日期：2021-01-01 00:00:00

abstract：:The question of whether neurons versus fibers of passage in the medial prefrontal cortex (MPC) are essential in maintaining self-stimulation of this same area of the brain was examined. Rats were prepared with electrode-guide cannulae implanted stereotaxically to rest within MPC. A micro-injection of (KA), 10 nmol/1.0...

journal_title：Brain research bulletin

authors： Ferrer JM,Myers RD,Mora F

更新日期：1985-08-01 00:00:00

abstract：:Traumatic brain injury (TBI) constitutes a heterogeneous cerebral insult induced by traumatic biomechanical forces. Mitochondria play a critical role in brain bioenergetics, and TBI induces several consequences related with oxidative stress and excitotoxicity clearly demonstrated in different experimental model involv...

journal_title：Brain research bulletin

authors： Courtes AA,Gonçalves DF,Hartmann DD,da Rosa PC,Cassol G,Royes LFF,de Carvalho NR,Soares FAA

更新日期：2020-10-01 00:00:00

abstract：:Sexually relevant pheromonal cues are detected by the vomeronasal system which includes the posterodorsal part of the medial amygdala, the posteromedial part of the bed nucleus of the stria terminalis and the medial preoptic area. Copulatory behavior is impaired in mice lacking functional aromatase, the enzyme convert...

journal_title：Brain research bulletin

authors： Aste N,Honda S,Harada N

更新日期：2003-05-15 00:00:00

abstract：:Comparison of detailed physiological and morphological data shows that the hypothalamic aggression region in the rat largely coincides with the intermediate hypothalamic area. This region has a neuronal density of about 35.10(3) neurons per mm3, a synaptic density of about 300.10(6) per mm3, and a synapse to neuron ra...

journal_title：Brain research bulletin

authors： Aalders TT,Meek J

更新日期：1993-01-01 00:00:00

abstract：:Transnuclear transport of horseradish peroxidase (HRP) and wheat germ agglutinin-HRP conjugate (WGA-HRP) and the retrograde transport of fluorescent tracers were used to study axon collaterals of neurons in the mamillary nuclei. Tracers were injected into the thalamus or brain stem and after 18 hour-5 day survival per...

journal_title：Brain research bulletin

authors： Takeuchi Y,Allen GV,Hopkins DA

更新日期：1985-05-01 00:00:00

abstract：:In the intact animal, some substantia nigra dopaminergic neurons exhibit regular, and some exhibit burst firing patterns. In the in vitro slice preparation, however, all dopaminergic neurons exhibit a nonburst firing pattern. Burst firing patterns are thought to be regulated, in part, by a small conductance calcium-ac...

journal_title：Brain research bulletin

authors： Gu X,Blatz AL,German DC

更新日期：1992-03-01 00:00:00

abstract：:Here we asked if insulin activation of the nucleus accumbens in vitro is reflected by an increase in (3)H-deoxyglucose ([(3)H]DG) uptake, thus subserving a new model to study molecular mechanisms of central insulin actions. Additionally, we investigated the dependence of this insulin effect on endocannabinoids and cor...

journal_title：Brain research bulletin

authors： Pinheiro BS,Lemos C,Neutzling Kaufmann F,Marques JM,da Silva-Santos CS,Carvalho E,Mackie K,Rodrigues RJ,Cunha RA,Köfalvi A

更新日期：2016-06-01 00:00:00

abstract：:Degenerating terminals were mapped by the Fink-Heimer method after lateral or fourth ventricular administration of 6-hydroxydopamine (60OHDA). This method marks dopaminergic terminals and has the advantage that noradrenergic terminals are not stained. Fink-Heimer stained degeneratig terminals were seen bilaterally in ...

journal_title：Brain research bulletin

authors： Hedreen J

更新日期：1980-07-01 00:00:00

abstract：:Electrophysiologic response characteristics of mouse sciatic nerve and spinal cord were investigated following CNS infection with the temperature-sensitive (ts) vesicular stomatitis virus (VSV) mutant G31 KS5. Measurements were obtained before clinical symptoms of the virus-induced CNS disease appeared. Sciatic nerve ...

journal_title：Brain research bulletin

authors： Gerren RA,Johnson TC

更新日期：1994-01-01 00:00:00

abstract：:Some C57Bl/6 mice become obese, whereas others remain lean when raised on a high-fat diet. The mechanisms underlying this interindividual susceptibility to diet-induced obesity remain unknown. Because hypothalamus plays a major role in the regulation of body weight, this study was conducted to identify the differences...

journal_title：Brain research bulletin

authors： Xin X,Storlien LH,Huang XF

更新日期：2000-07-01 00:00:00

abstract：:Electrical stimulation of the periaqueductal gray of the rat's midbrain analgesia leads to an increase in the number of artificial pulmonary metastases from the Walker 256 tumor. In an effort to investigate the influence of the pain suppression system and its associated peptides on this phenomenon, we activated the pa...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE,Lundy J

更新日期：1984-05-01 00:00:00

abstract：:Recent investigations of the nucleus ambiguus (NA) have attempted to identify motoneurons associated with the branchiomeric muscles of the larynx and pharynx. However, relatively little attention has been directed to the levator veli palatini muscle (LVP) which is critical in respiration, deglutition and eustachian tu...

journal_title：Brain research bulletin

authors： van Loveren H,Saunders MC,Keller JT

更新日期：1983-09-01 00:00:00

abstract：:Blood-brain barrier permeability (BBB) to the inhibitory neurotransmitter gamma-amino butyric acid (GABA) was studied in rats following intraperitoneal (i.p) injections of GABA alone and in combination with L-Arginine (L-Arg). Administration of GABA (600 mg/kg body weight [b. wt.]) alone increased brain GABA concentra...

journal_title：Brain research bulletin

authors： Shyamaladevi N,Jayakumar AR,Sujatha R,Paul V,Subramanian EH

更新日期：2002-01-15 00:00:00

abstract：:Reserpine depletes dopamine (DA) levels and increases tyrosine hydroxylase (TH) activity in the rat corpus striatum. TH is activated not only by enhancement of DA neuronal impulse flow, but also by cessation of impulse flow. To assist in the understanding of the relative contribution of impulse flow to the regulation ...

journal_title：Brain research bulletin

authors： German DC,McMillen BA,Sanghera MK,Saffer SI,Shore PA

更新日期：1981-02-01 00:00:00

abstract：:In the present study, multi-electrode array recording was used to examine dorsal horn activity following stimulation of primary afferents in a rat dorsal root attached-spinal cord slice preparation. The multi-electrode array probe was placed under the dorsal horn slice and local field potentials evoked by stimulation ...

journal_title：Brain research bulletin

authors： Yu F,Zhao ZY,He T,Yu YQ,Li Z,Chen J

更新日期：2017-05-01 00:00:00

abstract：:It is well known that some epileptic patients does not respond to conventional treatments, despite multiple combination of antiepileptic drugs, and they are therefore considered drug-resistant. For these patients, vagal nerve stimulation (VNS) represents a successful alternative to traditional therapy, and it is gener...

journal_title：Brain research bulletin

authors： Borghetti D,Pizzanelli C,Maritato P,Fabbrini M,Jensen S,Iudice A,Murri L,Sartucci F

更新日期：2007-06-15 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSCs) are involved in cancer initiation and metastasis, and sometimes mediate cell communication by releasing exosomes and delivering microRNAs (miRNAs). The study aims to investigate the effects of exosomal hsa-miR-23b-3p derived from human BMSCs on intracranial aneurysm (IA). Fir...

journal_title：Brain research bulletin

authors： Sun X,Zheng X,Zhang X,Zhang Y,Luo G

更新日期：2020-12-01 00:00:00

abstract：:Excised lateral eye retinular cells of Limulus polyphemus exposed to chlorobutanol were examined using microelectrode techniques. The effects observed were: (1) a marked shortening of the receptor potential latent period; (2) a decrease in the effective input resistance of retinular cells to hyperpolariziog currents; ...

journal_title：Brain research bulletin

authors： Wulff VJ,Jahy JL

更新日期：1977-05-01 00:00:00

abstract：:To investigate nitric oxide production in the brain of the EL mouse, an inbred mutant strain of the ddY mouse that is susceptible to convulsive seizures, we measured whole brain nitric oxide metabolites, and counted the number of nitric oxide-producing cells in the parietal cortex and striatum. Nitric oxide metabolite...

journal_title：Brain research bulletin

authors： Uchida M,Nagatomo I,Akasaki Y,Tominaga M,Hashiguchi W,Kuchiiwa S,Nakagawa S,Takigawa M

更新日期：1999-11-01 00:00:00

abstract：:Fourteen patients with high- (n = 7) and low-dose (n = 7) benzodiazepine (BDZ) dependency presented predominantly with anxious and depressive neurotic symptoms which caused long-term BDZ medication. Their BDZ dependency was characterized by giving preference to the abuse of benzodiazepines with long elimination half-l...

journal_title：Brain research bulletin

authors： Schmauss C,Apelt S,Emrich HM

更新日期：1987-09-01 00:00:00

abstract：:The effects of intracerebroventricular (ICV) injection of neuropeptide Y (NPY) on parameters of dopamine (DA), glutamate (Glu) and gamma-aminobutyric acid (GABA) activities were investigated in the rat striatum. NPY (1.17-4.70 nmol) induced a dose-dependent increase in the striatal endogenous DA release monitored in f...

journal_title：Brain research bulletin

authors： Kerkerian-Le Goff L,Forni C,Samuel D,Bloc A,Dusticier N,Nieoullon A

更新日期：1992-02-01 00:00:00

abstract：:The development of dopamine-immunoreactive (DAir) populations in the central nervous system of the sea lamprey, a modern representative of the earliest vertebrates, was studied to achieve further understanding of dopaminergic systems in vertebrates. The first DAir cell groups appeared in the spinal cord, the posterior...

journal_title：Brain research bulletin

authors： Abalo XM,Villar-Cheda B,Anadón R,Rodicio MC

更新日期：2005-09-15 00:00:00

abstract：:This study investigated the effects of neonatal unilateral adrenalectomy on the serotonin- (5-HT) and thyrotropin-releasing hormone-like immunoreactivities (TRH-LI) in the intermediolateral cell column (IML) of the rat spinal cord where the sympathetic preganglionic neurons innervating the adrenal medulla are located....

journal_title：Brain research bulletin

authors： Poulat P,Marlier L,Rajaofetra N,Privat A

更新日期：1993-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the histamine H1-receptor blocker, chlorpheniramine (CPA), has a reinforcing effect in goldfish. We used a place-preference procedure in an aquarium with two chambers colored black and white. On day 1, the animals were placed in the test chamber for 10 min for habituati...

journal_title：Brain research bulletin

authors： Mattioli R,Nelson CA,Huston JP,Spieler RE

更新日期：1998-01-01 00:00:00

abstract：:Behavioral adaptations exhibited by two African fossorial mammals for the reception of vibrational signals are discussed. The Namib Desert golden mole (Eremitalpa granti namibensis) is a functionally blind, nocturnal insectivore in the family Chrysochloridae that surface forages nightly in the Namib desert. Both geoph...

journal_title：Brain research bulletin

authors： Narins PM,Lewis ER,Jarvis JJ,O'Riain J

更新日期：1997-01-01 00:00:00

abstract：:The possible competition of MIF-1 (Pro-Leu-Gly-NH2) with 3H-naloxone or 3H-D-Ala-D-Leu-enkephalin (DADLE) for mu and delta opiate receptors in the rat striatum was examined under conditions of varying temperatures and concentrations of sodium and GTP. MIF-1, in concentrations ranging from 10(-14) to 10(-3) M, failed t...

journal_title：Brain research bulletin

authors： Luciano MG,Zadina JE,Kastin AJ,Coy DH

更新日期：1981-12-01 00:00:00

abstract：:Spontaneous locomotion and motor coordination was evaluated in young (5-6 month old) and aged (24-25 month old) rats. Animals were tested for spontaneous locomotor activity in Digiscan Animal Activity Monitors during the nocturnal cycle. Aged animals exhibited a significant hypoactivity compared to their young counter...

journal_title：Brain research bulletin

authors： Emerich DF,McDermott P,Krueger P,Banks M,Zhao J,Marszalkowski J,Frydel B,Winn SR,Sanberg PR

更新日期：1993-01-01 00:00:00