Beta-endorphin injected into the nucleus of the raphe magnus facilitates metastatic tumor growth.

abstract：:The subparafascicular thalamic nucleus (Spf) contains a substantial number of dopaminergic neurons. The present study was designed to investigate in the rat whether or not Spf neurons projecting to a variety of central nervous system structures are dopaminergic. The following eight structures were tested for projectio...

journal_title：Brain research bulletin

authors： Takada M

更新日期：1993-01-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a common neurological disease, causing severe disability and even deaths. Stem cell transplantation has been increasingly used in stroke therapy, and neural stem cells (NSCs) are a good source for stem cell transplantation. However, the regulatory mechanism of NSCs remains unclear. In...

journal_title：Brain research bulletin

authors： Sun Z,Wu K,Gu L,Huang L,Zhuge Q,Yang S,Wang Z

更新日期：2020-11-01 00:00:00

abstract：:The effects of unilateral cortical spreading depression (CSD) on feeding, drinking and other behaviors were studied in rats. CSD waves were elicited by a microinjection of KC1 solution through an implanted cannula. The animal's behavior and slow potential changes (SPC) accompanying CSD were then simultaneously monitor...

journal_title：Brain research bulletin

authors： Shibata M

更新日期：1978-07-01 00:00:00

abstract：:The chronic mild stress (CMS) model has been used as an animal model of depression which induces anhedonic behavior in rodents. The present study was aimed to evaluate the behavioral and physiological effects of administration of beta-carboline harmine in rats exposed to CMS procedure. To this aim, after 40 days of ex...

journal_title：Brain research bulletin

authors： Fortunato JJ,Réus GZ,Kirsch TR,Stringari RB,Fries GR,Kapczinski F,Hallak JE,Zuardi AW,Crippa JA,Quevedo J

更新日期：2010-03-16 00:00:00

abstract：:A newly developed technique employing the retrograde transport of horseradish peroxidase combined with immunocytochemistry is used to identify the cells of origin of descending spinal pathways and their putative neurotransmitters. With this technique the brainstem origins of descending serotonergic (5HT) pathways to t...

journal_title：Brain research bulletin

authors： Bowker RM,Westlund KN,Coulter JD

更新日期：1982-07-01 00:00:00

abstract：:Mouse models that replicate facets of human neurological diseases are often used at the pre-clinical stage to better understand the underlying mechanisms of a disease and test the target engagement of potential therapeutic interventions. We recently characterized a mouse model of childhood-onset parkinsonism-dystonia,...

journal_title：Brain research bulletin

authors： Giraldo G,Janus C

更新日期：2021-01-01 00:00:00

abstract：:The distribution of tissue plasminogen activator (tPA) messenger RNA in rat brain was studied using in situ hybridization with 35S UTP-labeled RNA probes derived from a full-length tPA cDNA. Sense strand controls produced low, even backgrounds, with small elevations in the hippocampus. Full-length antisense probes pro...

journal_title：Brain research bulletin

authors： Ware JH,Dibenedetto AJ,Pittman RN

更新日期：1995-01-01 00:00:00

abstract：:Cocaine is a major stimulant drug which can have rewarding and locomotor activating effects. It is used by non-addicts to enhance concentration and performance in a work or social setting. It was suggested that cocaine may amplify the impact of mood and sensory stimulation on behaviour. Here we tested whether cocaine ...

journal_title：Brain research bulletin

authors： Pum ME,Rubio AR,Carey RJ,Silva MA,Müller CP

更新日期：2011-02-28 00:00:00

abstract：:The medial preoptic area is a key structure in the neural control of reproduction. Considerable evidence has accumulated indicating that glutamatergic innervation of the area plays an important role in this control. Sources of the glutamatergic input are unknown. Present investigations were aimed at studying this ques...

journal_title：Brain research bulletin

authors： Kocsis K,Kiss J,Csáki A,Halász B

更新日期：2003-08-30 00:00:00

abstract：:To elucidate the role of the medial basal hypothalamus (MBH) in stress-induced prolactin (Prl) release, adult male rats which had received monosodium glutamate (MSG 4 mg/g) on alternate days for the first 10 days of life were subjected to ether stress for 2 min. Blood samples were drawn at 0, 15, 30 and 60 min after e...

journal_title：Brain research bulletin

authors： Mizunuma H,Khorram O,McCann SM

更新日期：1983-01-01 00:00:00

abstract：:It is generally assumed that the primary response of the rat flash evoked potential (FEP) is activated by a retino-geniculate path, and that the secondary response reflects input to the cortex by way of the superior colliculus (SC) or other brainstem structures. In the present study, male Long-Evans rats were implante...

journal_title：Brain research bulletin

authors： Barnes MI,Dyer RS

更新日期：1986-02-01 00:00:00

abstract：:This paper provides an introduction to a special issue dedicated to the action of environmental estrogens on neural circuits and behavior. The problem of endocrine disrupting chemicals (EDCs), i.e. chemicals that have the capacity to interfere with the endocrine system, has gained increasing attention as it has become...

journal_title：Brain research bulletin

authors： Panzica GC,Viglietti-Panzica C,Ottinger MA

更新日期：2005-04-15 00:00:00

abstract：:The present study investigated whether the raphe neurons which give rise to the transient serotonergic fibers in the visual cortex of neonatal rats persist or disappear as the rats mature. Three experiments were performed employing the WGA-apoHRP-Au retrograde transport technique in conjunction with 5-HT or WGA-HRP im...

journal_title：Brain research bulletin

authors： Koh T,Nakazawa M,Kani K,Maeda T

更新日期：1991-11-01 00:00:00

abstract：:Perinatal exposure to delta 9-THC has been shown to produce effects on brain development. In this study we evaluated the changes induced by maternal exposure to delta 9-THC (5 mg/kg per day) from gestational day 5 to postnatal day 24 in eight discrete brain areas on the central serotoninergic system in both adult male...

journal_title：Brain research bulletin

authors： Molina-Holgado F,Alvarez FJ,Gonzalez I,Antonio MT,Leret ML

更新日期：1997-01-01 00:00:00

abstract：:The influence of gender and stage of the estrous cycle on the levels of acetylcholine, serotonin, and noradrenaline in the hippocampus and on the susceptibility of the cholinergic septo-hippocampal pathway to the neurotoxic effect of ethylcholine aziridinium (AF64A) was investigated in the rat. Levels of acetylcholine...

journal_title：Brain research bulletin

authors： Hörtnagl H,Hansen L,Kindel G,Schneider B,el Tamer A,Hanin I

更新日期：1993-01-01 00:00:00

abstract：:Depression and anxiety have been reported as the major neuropsychiatric consequences following stroke. Minocycline, a neuroprotective drug has minimized depressive symptoms in patients with major depressive disorders and anxiety-like symptoms. In addition, minocycline demonstrated efficacy and seemed a promising neuro...

journal_title：Brain research bulletin

authors： Camargos QM,Silva BC,Silva DG,Toscano ECB,Oliveira BDS,Bellozi PMQ,Jardim BLO,Vieira ÉLM,de Oliveira ACP,Sousa LP,Teixeira AL,de Miranda AS,Rachid MA

更新日期：2020-02-01 00:00:00

abstract：:Aluminium is highly neurotoxic and inhibits prenatal and postnatal development of the brain in humans and experimental animals. However, the incorporation of aluminium into the brain of fetuses and sucklings during gestation and lactation has not been well clarified because aluminium lacks a suitable isotope for a tra...

journal_title：Brain research bulletin

authors： Yumoto S,Nagai H,Matsuzaki H,Matsumura H,Tada W,Nagatsuma E,Kobayashi K

更新日期：2001-05-15 00:00:00

abstract：:Somatosensory input to 431 neurons in MsI has been studied in unanesthetized, paralyzed raccoons (Procyon lotor). The type of sensory input to neurons in lateral sigmoid gyrus (cytoarchitectonic area 4) and in posterior sigmoid gyrus (areas 4 and 3a) was not significantly different. Of these neurons, 36% were activate...

journal_title：Brain research bulletin

authors： Gugino LD,Rowinski MJ,Stoney SD Jr

更新日期：1990-06-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people over 60 years of age in the US and many other developed countries. Increasingly sophisticated methods for the diagnosis and treatment of macular degeneration are not effective for the majority of patients in whom late stage...

journal_title：Brain research bulletin

authors： Rowe-Rendleman C,Glickman RD

更新日期：2004-02-15 00:00:00

abstract：:The effect of regucalcin, a Ca(2+)-binding protein, on Ca(2+)-dependent protein kinase activity in the brain cytosol of rats with different ages (5 and 50 weeks old) was investigated. The addition of calmodulin (10 microg/ml) or dioctanoylglycerol (5 microg/ml) in the enzyme reaction mixture caused a significant incre...

journal_title：Brain research bulletin

authors： Hamano T,Hanahisa Y,Yamaguchi M

更新日期：1999-10-01 00:00:00

abstract：:In this study we investigated the ability of the dentate gyrus to independently generate cholinergically induced theta rhythm in vitro. Two different experiments were performed. In Experiment I, new laminar profiles of theta phase, amplitude, and current sources and sinks were constructed. In this experiment a gradual...

journal_title：Brain research bulletin

authors： Kowalczyk T,Gołebiewski H,Konopacki J

更新日期：2009-09-28 00:00:00

abstract：:Seizure activity stimulates adult neurogenesis, the birth of new neurons, in the hippocampus. Many new neurons that develop in the presence of repeatedly induced seizures acquire abnormal morphological and functional characteristics that can promote network hyperexcitability and hippocampal dysfunction. However, the i...

journal_title：Brain research bulletin

authors： Kalinina A,Maletta T,Carr J,Lehmann H,Fournier NM

更新日期：2019-10-01 00:00:00

abstract：:Unit activities of thermosensitive (TS) and non-TS neurons in the medial preoptic area (MPO) of the monkey were investigated during a high fixed-ratio (FR 12-30) bar press behavior to seek cool air (CT) in a warm environment. The monkey performed the task when ambient temperature (Ta) was raised (35-43 degrees C) and ...

journal_title：Brain research bulletin

authors： Hori T,Kiyohara T,Oomura Y,Nishino H,Aou S,Fujita I

更新日期：1987-05-01 00:00:00

abstract：:Taurine's site of action within the central nervous system was localized by studying its effect on prolactin secretion following the microinfusion of 125 nmoles of this amino acid into discrete regions of the brain. Taurine was found to stimulate prolactin secretion only when microinfused into the arcuate nucleus of t...

journal_title：Brain research bulletin

authors： Scheibel J,Elsasser T,Brown B,Dom R,Ondo JG

更新日期：1984-07-01 00:00:00

abstract：:Early life Stress is a worldwide concern linked with development of later life neurological disorders. Early developmental age is sensitive to many prominent environmental insults like malnourishment, immune inflammation, abuse, maternal separation, alcohol and drugs. Hence, an individual during an early age encounter...

journal_title：Brain research bulletin

authors： Sarkar T,Patro N,Patro IK

更新日期：2019-04-01 00:00:00

abstract：:Individual cardiac nerves from which stimulation elicited cardioinhibition (bradycardia and negative inotropism) were identified in 24 of 38 dogs. Subsequently, 3-25 microliters of 30% horseradish peroxidase (HRP) were injected into an identified cardiac nerve. After a 3-day survival period, the medulla oblongata was ...

journal_title：Brain research bulletin

authors： Hopkins DA,Armour JA

更新日期：1982-04-01 00:00:00

abstract：:The lateral hypothalamic area (LHA) and globus pallidus (GP) are basically involved in the regulation of feeding and metabolic processes. In the LHA, glucose-sensitive (GS) neurons were described: their activity was found to be specifically suppressed by electrophoretic application of glucose, and these neurons appear...

journal_title：Brain research bulletin

authors： Lénárd L,Karádi Z,Faludi B,Czurkó A,Niedetzky C,Vida I,Nishino H

更新日期：1995-01-01 00:00:00

abstract：:Cerebral malaria (CM) is the severe neurological complication associated with Plasmodium falciparum infection. In clinical settings CM is predominantly characterized by fever, epileptic seizures, and asexual forms of parasite on blood smears, coma and even death. Cognitive impairment in the children and adults even af...

journal_title：Brain research bulletin

authors： Vanka R,Nakka VP,Kumar SP,Baruah UK,Babu PP

更新日期：2020-04-01 00:00:00

abstract：:In a previous study we showed that healthy highly hypnotizable subjects, during the suggestion of a moderately unpleasant situation administered in awake conditions, exhibited a sympathetic response greatly attenuated with respect to non-hypnotizable individuals. This was interpreted as a natural protection of hypnoti...

journal_title：Brain research bulletin

authors： Gemignani A,Sebastiani L,Simoni A,Santarcangelo EL,Ghelarducci B

更新日期：2006-03-31 00:00:00

abstract：:Development and resolution of the lesion produced by occlusion of the middle cerebral artery (MCAO) was studied through quantitative planimetry and histologic/immunohistochemical techniques. MCAO, performed in spontaneously hypertensive rats (SHR), initially (1-3 days) produced large, consistent cerebral cortical infa...

journal_title：Brain research bulletin

authors： Clark RK,Lee EV,Fish CJ,White RF,Price WJ,Jonak ZL,Feuerstein GZ,Barone FC

更新日期：1993-01-01 00:00:00