Nitric oxide production is decreased in the brain of the seizure susceptible EL mouse.

abstract：:The effects of two diketopiperazines, Cyclo (His-Pro) (CHP) and Cyclo (Asp-Phe) (CAP), on striatal extracellular levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) were examined using in vivo microdialysis in anaesthetized rats. Treatment with ...

journal_title：Brain research bulletin

authors： Kaakkola S,Wurtman RJ

更新日期：1993-01-01 00:00:00

abstract：:Adult male Sprague-Dawley rats were made paraplegic by a complete transection of the spinal cord at lower thoracic level. One week later they were transplanted, below the level of the section, with a cell suspension prepared from the raphe region of 14-day embryos. After survival periods of 10 days to 1 year, the anim...

journal_title：Brain research bulletin

authors： Privat A,Mansour H,Rajaofetra N,Geffard M

更新日期：1989-01-01 00:00:00

abstract：:Male and female rats were treated daily for 7 days with mazindol (5, 10, and 20 mg/kg), an anorectic drug, and tested in the open field. Mazindol developed sensitization to its locomotor stimulatory effect in both sexes on day 7 with a nondose-dependent pattern of response. However, the locomotor activity appeared to ...

journal_title：Brain research bulletin

authors： Zanin M,Takahashi RN

更新日期：1994-01-01 00:00:00

abstract：:Walker 256 carcinosarcoma cells produce subpleural pulmonary metastases when given intravenously to the Sprague-Dawley rat. The number of metastases increases when the rat is given morphine subsequent to the tumor load. The increase in the number of metastases can be blocked be pretreatment with the opiate antagonist ...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE

更新日期：1986-03-01 00:00:00

abstract：:Data from clinical investigations and laboratory fundings have provided preliminary evidence for the effectiveness and safety of acupuncture therapy in depression. However, the mechanisms underlying the antidepressant response of acupuncture are not fully elucidated. To elucidate the potential effects of acupuncture f...

journal_title：Brain research bulletin

authors： Wang Y,Jiang H,Meng H,Lu J,Li J,Zhang X,Yang X,Zhao B,Sun Y,Bao T

更新日期：2017-09-01 00:00:00

abstract：:Single unit activity was recorded in the neocortex of awake cats during spontaneous spike wave discharges. Ongoing activity was interrupted during paroxysmal events and was replaced by (1) bursts of action potentials coincident with the EEG spike and cessation of firing during the wave, or (2) cessation of firing for ...

journal_title：Brain research bulletin

authors： Wray DV,Hablitz JJ

更新日期：1977-09-01 00:00:00

abstract：:A modified synaptosomal superfusion apparatus is described which uses less than 10 micrograms of tissue per replicate sample and facilitates the routine separation of 3H-DA, 3H-DOPAC, and 3H-HVA. A flow rate of 1.5 ml/min allows superfusion without the use of reuptake or monoamine oxidase inhibitors. Superfusate sampl...

journal_title：Brain research bulletin

authors： Petrie EC,Lombrozo L,Csernansky JG

更新日期：1990-09-01 00:00:00

abstract：:It is well known that some epileptic patients does not respond to conventional treatments, despite multiple combination of antiepileptic drugs, and they are therefore considered drug-resistant. For these patients, vagal nerve stimulation (VNS) represents a successful alternative to traditional therapy, and it is gener...

journal_title：Brain research bulletin

authors： Borghetti D,Pizzanelli C,Maritato P,Fabbrini M,Jensen S,Iudice A,Murri L,Sartucci F

更新日期：2007-06-15 00:00:00

abstract：:The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) is involved in several morphogenetic processes of the central nervous system. In the present study the expression of PSA-NCAM has been investigated in the rat thalamus during embryonic and postnatal development using light and electron microscopic...

journal_title：Brain research bulletin

authors： Mazzetti S,Ortino B,Inverardi F,Frassoni C,Amadeo A

更新日期：2007-03-30 00:00:00

abstract：:The place conditioning paradigm has proven successful in identifying the neural mechanisms of drug reinforcement. Two classes of drugs, opiates and psychomotor stimulants, have received the most study, and in each case an important role for DA neurons of the mesolimbic system has been established. Moreover, both recep...

journal_title：Brain research bulletin

authors： Hoffman DC

更新日期：1989-10-01 00:00:00

abstract：:Neurochemical and morphological effects of neonatal anoxia on monoamine systems were studied after 100% N2 exposure for 25 min at 30 h postnatally (postnatal day 2-P2). At 20 min after anoxia, reductions of tissue levels of cerebellar noradrenaline (NA) and striatal dopamine (DA) and metabolites were seen, while 5-hyd...

journal_title：Brain research bulletin

authors： Dell'Anna ME,Luthman J,Lindqvist E,Olson L

更新日期：1993-01-01 00:00:00

abstract：:Fluoro-Ruby (tetramethylrhodamine-dextran amine conjugate) has been shown recently to be an effective anterograde tracer readily visible in brain sections with fluorescence microscopy. We show in this study that further microscopic analysis of Fluoro-Ruby-labeled elements is feasible with a conventional immunoperoxida...

journal_title：Brain research bulletin

authors： Chang HT

更新日期：1993-01-01 00:00:00

abstract：:The unique noradrenergic and specific serotonergic antidepressant mirtazapine acts antinociceptive. It is optically active and currently marketed as racemate. In an animal model of acute pain it has been shown that the enantiomers exhibit differential effects: the R(-)-enantiomer showed anti-, the S(+)-enantiomer pron...

journal_title：Brain research bulletin

authors： Muth-Selbach U,Hermanns H,Driehsen C,Lipfert P,Freynhagen R

更新日期：2009-04-06 00:00:00

abstract：:The present study was conducted to evaluate plasma levels of monoamine neurotransmitter metabolites in spontaneous recurrences of methamphetamine psychosis (i.e., flashbacks). The subjects were 50 physically healthy females comprised of 25 who experienced flashbacks (flashbackers), 18 who did not experienced methamphe...

journal_title：Brain research bulletin

authors： Yui K,Goto K,Ikemoto S,Ishiguro T

更新日期：1997-01-01 00:00:00

abstract：:An evaluation of N,N-dipropargyl-2-phenylethylamine (DPGPEA) as a prodrug to increase brain levels of 2-phenylethylamine (PEA) was conducted in rats. A 0.1 mmol/kg (IP) dose of DPGPEA was administered and produced marked elevations of PEA levels in brain, liver and blood which were sustained for several hours. Ex vivo...

journal_title：Brain research bulletin

authors： Rao TS,Baker GB,Coutts RT

更新日期：1987-07-01 00:00:00

abstract：:The effects of unilateral cortical spreading depression (CSD) on feeding, drinking and other behaviors were studied in rats. CSD waves were elicited by a microinjection of KC1 solution through an implanted cannula. The animal's behavior and slow potential changes (SPC) accompanying CSD were then simultaneously monitor...

journal_title：Brain research bulletin

authors： Shibata M

更新日期：1978-07-01 00:00:00

abstract：:The effect of the intracerebroventricular (ICV) administration of pertussis toxin on penile erection and yawning induced by apomorphine and oxytocin was studied in male rats. Pertussis toxin (2 micrograms ICV) prevented the above behavioral responses to apomorphine (80 micrograms/kg SC) and oxytocin (30 ng ICV) on day...

journal_title：Brain research bulletin

authors： Stancampiano R,Melis MR,Argiolas A

更新日期：1992-02-01 00:00:00

abstract：:Although originally developed as a research tool for studying glial-glial and glial-axonal interactions, the technique of transplanting glial cell into the central nervous system has more recently been employed as a potential means for repairing persistent demyelination in clinical disease. It has now been clearly est...

journal_title：Brain research bulletin

authors： Franklin RJ

更新日期：2002-04-01 00:00:00

abstract：:The distribution of calcitonin gene-related peptide (CGRP)-like immunoreactive (LI) nerve cells and terminals (BST) was studied in the rat. Only the fusiform nucleus was found to consistently contain CGRP-LI neurons. The CRGP-LI terminals had a wide distribution in the BST, being most numerous in the oval and the fusi...

journal_title：Brain research bulletin

authors： Ju G

更新日期：1991-11-01 00:00:00

abstract：:Single unit recordings were used to map the spatial distribution of motor (MI) cortical influences on thalamic somatosensory relay nuclei in the rat. A total of 215 microelectrode penetrations were made to record single neurons in tracks through the medial and lateral ventroposterior (VPM and VPL), ventrolateral (VL),...

journal_title：Brain research bulletin

authors： Shin HC,Chapin JK

更新日期：1990-02-01 00:00:00

abstract：:Cellular and molecular mechanisms involved in the generation of seizures and the magnitude of neural cells injury are not fully understood. We evaluated astrocyte and/or neuronal injury in rats in the pentylenetetrazol model of acute seizures by measuring S100B and NSE levels in cerebrospinal fluid. Additionally, we d...

journal_title：Brain research bulletin

authors： Oses JP,Leke R,Portela LV,Lara DR,Schmidt AP,Casali EA,Wofchuk S,Souza DO,Sarkis JJ

更新日期：2004-09-30 00:00:00

abstract：:Our previous study demonstrated that single intrathecal (i.t.) application of fluorocitrate, a glial metabolic inhibitor, synergized electroacupuncture (EA) antagonizing behavioral hypersensitivity in complete Freund's adjuvant (CFA)-induced monoarthritic rat. To further investigate the relationship between spinal gli...

journal_title：Brain research bulletin

authors： Sun S,Cao H,Han M,Li TT,Zhao ZQ,Zhang YQ

更新日期：2008-01-31 00:00:00

abstract：:This investigation assessed the relative reliability of the human auditory evoked potential (AEP) amplitude-intensity and latency-intensity functions. Averaged AEP waveforms to 10 levels of stimulus magnitude were obtained from bipolar recordings. Variability and slope of group functions were constant, as indicated by...

journal_title：Brain research bulletin

authors： Browman CP,Sullivan HT

更新日期：1980-03-01 00:00:00

abstract：:Evidence concerning the presence or absence of common neuronglia lineages in the postnatal mammalian central nervous system is still a matter of speculation. We address this problem using optic nerve explants, which show an extremely long survival in culture. Morphological, immunocytochemical and immunochemical method...

journal_title：Brain research bulletin

authors： Omlin FX,Riederer BM

更新日期：1992-01-01 00:00:00

abstract：:As human brain development proceeds, there are complex changes in size and shape, most notably in the developing forebrain. Molecular technologies enable us to characterise the gene expression patterns that underlie these changes. To interpret these patterns the location of expression must be identified and, often, ge...

journal_title：Brain research bulletin

authors： Sarma S,Kerwin J,Puelles L,Scott M,Strachan T,Feng G,Sharpe J,Davidson D,Baldock R,Lindsay S

更新日期：2005-09-15 00:00:00

abstract：:Serotonergic modulation of acetylcholine (ACh) release after neuron-specific increase of the expression of 5-HT(1B) receptors by gene transfer was studied in vitro and in vivo. The increased expression of the 5-HT(1B) receptor in vitro was induced by treating rat primary fetal septal cell cultures for 3 days with a vi...

journal_title：Brain research bulletin

authors： Riegert C,Rothmaier AK,Leemhuis J,Sexton TJ,Neumaier JF,Cassel JC,Jackisch R

更新日期：2008-07-01 00:00:00

abstract：:There is some experimental evidence that the pallial areas of a fish's brain are involved in distincted learning functions. Recently published data suggest that the medial pallium is essential for avoidance learning and the lateral pallium is crucial for spatial learning and is also involved in temporal aspects of the...

journal_title：Brain research bulletin

authors： Vargas JP,López JC,Portavella M

更新日期：2009-08-14 00:00:00

abstract：:The effects of a low protein diet during gestation, lactation, and after weaning on the anatomical development of a subcortical nucleate formation, the neostriatum, and a reticulate formation, the diagonal band of Broca, were studied. At 10, 30, and 90 days the volume of the neostriatum was decreased in the experiment...

journal_title：Brain research bulletin

authors： Kemper TL,Pasquier DA,Drazen S

更新日期：1978-09-01 00:00:00

abstract：:GABA(A) receptors are chloride channels in the brain activated by binding of gamma-aminobutyric acid (GABA). Several important classes of drugs, including alcohol and certain antiepileptic drugs, modulate the actions of GABA. We report the sequence and expression of alpha4 subunits of GABA(A) receptors in two inbred s...

journal_title：Brain research bulletin

authors： Cestari IN,Liu ZF,Mu W,Burt DR

更新日期：1998-12-01 00:00:00

abstract：:Cell replacement therapy is of great interest as a long-term treatment of neurodegenerative diseases such as Parkinson's disease (PD). We have previously shown that Sertoli cells (SC) provide neurotrophic support to transplants of dopaminergic fetal neurons and NT2N neurons, derived from the human clonal precursors ce...

journal_title：Brain research bulletin

authors： Saporta S,Willing AE,Shamekh R,Bickford P,Paredes D,Cameron DF

更新日期：2004-12-15 00:00:00