The opposite effect of a 5-HT1B receptor agonist on 5-HT synthesis, as well as its resistant counterpart, in an animal model of depression.

abstract：:The putative behavioral effects of the enantiomers of BAY K 8644 and the behavioral responses to (+/-)-BAY K 8644 following chronic injection were assessed on motor function in mice. The interaction of the enantiomers of BAY K 8644 with mouse brain dihydropyridine binding sites was also evaluated. The calcium channel ...

journal_title：Brain research bulletin

authors： O'Neill SK,Bolger GT

更新日期：1988-12-01 00:00:00

abstract：:Secondary brain injuries following intracerebral hemorrhage (ICH) are mediated by inflammatory pathway activation. The present study aimed to characterize long noncoding RNAs (lncRNAs) that are differentially expressed in cerebral tissues during ICH pathogenesis and to investigate their pathogenic functions. An ICH mo...

journal_title：Brain research bulletin

authors： Chen JX,Wang YP,Zhang X,Li GX,Zheng K,Duan CZ

更新日期：2020-09-01 00:00:00

abstract：:A number of procedures exist for the experimental induction of sodium appetite. With the exception of a low sodium diet, nearly all of these methods are invasive, requiring injections, surgery, or both. In addition to stimulating intake of concentrated salt, some of them produce substantial side-effects like reduced f...

journal_title：Brain research bulletin

authors： Caloiero VG,Lundy RF

更新日期：2004-07-30 00:00:00

abstract：:The role of calmodulin (CaM) in organelle motility (fast axonal transport) in the axoplasm of the squid giant axon was evaluated directly using video-enhanced microscopy. Addition of 6 microM CaM to extruded squid axoplasm produced a 2.6-fold increase in the number of organelles moving per minute per unit area of axop...

journal_title：Brain research bulletin

authors： Rivera DT,Langford GM,Weiss DG,Nelson DJ

更新日期：1995-01-01 00:00:00

abstract：:In response to the growing interest in the prosimian Microcebus murinus for studies on cerebral aging, the stereotaxic atlas of its brain was carried out in view of further anatomical, biochemical, electrophysiological, and behavioral investigations as well as for therapeutic experiments. This primate, which could be ...

journal_title：Brain research bulletin

authors： Bons N,Silhol S,Barbié V,Mestre-Francés N,Albe-Fessard D

更新日期：1998-05-01 00:00:00

abstract：:In brainstem slices of male rats, we examined in single neurons of the medial vestibular nucleus (MVN) the effect of exogenous administration of estrogenic (17β-estradiol, E2) and androgenic (5α-dihydrotestosterone, DHT) steroids on the synaptic response to vestibular afferent stimulation. By whole cell patch clamp re...

journal_title：Brain research bulletin

authors： Grassi S,Scarduzio M,Panichi R,Dall'Aglio C,Boiti C,Pettorossi VE

更新日期：2013-08-01 00:00:00

abstract：:The contribution deals with the distribution of alkaline phosphatase and 5-nucleotidase in the medulla oblongata of Taphozous melanopogon (a Microchiroptera), for the first time. The main highlights of the study are: (1) Cranial nerve nuclei demonstrate intense activity of alkaline phosphatase, whereas except nucleus ...

journal_title：Brain research bulletin

authors： Hafiza B,Sood PP

更新日期：1979-07-01 00:00:00

abstract：:We have studied the effects of 14-methoxymetopon (HS 198), a potent opioid agonist, on the responses to the tail electric stimulation test and plus-maze activity of adult male rats. The prototype mu agonist morphine was used as the drug of reference. Besides we addressed the effects of HS 198 on the serum corticostero...

journal_title：Brain research bulletin

authors： Urigüen L,Fernández B,Romero EM,De Pedro N,Delgado MJ,Guaza C,Schmidhammer H,Viveros MP

更新日期：2002-03-15 00:00:00

abstract：:We have examined the effects of the presence of the mutated human presenilin 1 gene (M146L; hps1*) on lesion-induced sprouting in the hippocampus of the mouse (C57/CBA). The entorhinal cortex was unilaterally lesioned with ibotenic acid in adult, male mice. Four weeks later the subsequent axonal sprouting in the denta...

journal_title：Brain research bulletin

authors： Kadish I,Pradier L,van Groen T

更新日期：2002-03-15 00:00:00

abstract：PURPOSE:We assessed the potential of resting-state fMRI lag analysis (RSLA) in detecting epileptic activation and in estimating anti-epileptic effects of Levetiracetam (LEV) in Rolandic epilepsy. METHODS:Forty-three children with Rolandic epilepsy underwent simultaneous EEG-fMRI. They were grouped into LEV vs drug-naï...

journal_title：Brain research bulletin

authors： Xu Q,Hu Z,Yang F,Bernhardt BC,Zhang Q,Stufflebeaskm SM,Zhang Z,Lu G

更新日期：2020-09-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) receives a direct retinal projection, which in rats includes substance P (SP)-immunoreactive retinal ganglion cells. While SP has been shown to have neurophysiological effects on SCN cells in Syrian hamsters and rats, it is not known what effects SP in the SCN has on circadian rhythms...

journal_title：Brain research bulletin

authors： Piggins HD,Rusak B

更新日期：1997-01-01 00:00:00

abstract：:IN anesthetized and paralyzed rabbits, action potentials were elicited antidromically following electrical stimulation of optic tract terminals at the geniculate level (LGN). The conduction velocity spectrum extended from 7 m.s-1 to 34 m.s-1. The distribution of conduction velocities indicated four major modes at 10, ...

journal_title：Brain research bulletin

authors： Molotchnikoff S,Lessard I

更新日期：1980-11-01 00:00:00

abstract：:The projections from the rat medial prefrontal cortex to the amygdaloid complex were investigated using retrograde transport of fluorescent dyes and anterograde transport of horseradish peroxidase-WGA. The ventral anterior cingulate, prelimbic, infralimbic and medial orbital areas and the taenia tecta were found to pr...

journal_title：Brain research bulletin

authors： Cassell MD,Wright DJ

更新日期：1986-09-01 00:00:00

abstract：:Single-nucleotide polymorphism (SNP) and Alternative splicing (AS) were found to be implicated in certain diseases, nevertheless, the contributions of mRNA SNPs and AS to pathogenesis in developing rat brains with hypoxic-ischemic encephalopathy (HIE) remained largely vague. Additionally, the disease associated with T...

journal_title：Brain research bulletin

authors： Xue LL,Wang F,Xiong LL,Du RL,Zhou HL,Zou Y,Wu MX,Yang MA,Dai J,He MX,Wang TH

更新日期：2020-01-01 00:00:00

abstract：:This study is a summary of investigations in the last decade with several collaborators on representatives of different vertebrate stocks. The results suggest that in the main vertebrate stocks (Agnathi, Chondrichthyes, Actinopterygii, Sarcopterygii-Amniotes), which had their parallel brain evolutions from the laminar...

journal_title：Brain research bulletin

authors： Kálmán M

更新日期：2002-02-01 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:Image analysis methods are being developed for measuring the density and distribution of perivascular noradrenergic nerves and their varicosities, demonstrated by fluorescence histochemistry. Image analysis is recommended in comparison with other methods for the quantitation of fluorescence, because image resolution i...

journal_title：Brain research bulletin

authors： Cowen T,Burnstock G

更新日期：1982-07-01 00:00:00

abstract：:A modified synaptosomal superfusion apparatus is described which uses less than 10 micrograms of tissue per replicate sample and facilitates the routine separation of 3H-DA, 3H-DOPAC, and 3H-HVA. A flow rate of 1.5 ml/min allows superfusion without the use of reuptake or monoamine oxidase inhibitors. Superfusate sampl...

journal_title：Brain research bulletin

authors： Petrie EC,Lombrozo L,Csernansky JG

更新日期：1990-09-01 00:00:00

abstract：:The effects of chronic administration of delta 9-tetrahydrocannabinol (delta 9-THC) on the plasma and brain catecholamine (CA) levels were measured using high performance liquid chromatography-electrochemical detection (LC-EC) system. Intact male rats were injected daily with vehicle (50 microliter oil) or with delta ...

journal_title：Brain research bulletin

authors： Patel V,Borysenko M,Kumar MS

更新日期：1985-01-01 00:00:00

abstract：:In the frog Rana esculenta the left dorsal habenula includes a lateral and a medial component, whereas the right dorsal habenula is only represented by one nucleus. The efferents of the habenular nuclei to the interpeduncular nucleus were herein investigated with the retrograde horseradish peroxidase tracing. Injectio...

journal_title：Brain research bulletin

authors： Gugliemotti V,Fiorino L

更新日期：1998-01-01 00:00:00

abstract：:The discovery of spontaneous neuronal replacement in the adult vertebrate brain has changed the way in which we think about the biology of memory. This is because neuronal replacement is likely to have an impact on what a brain remembers and what it learns. Neuronal replacement has also changed the way in which we go ...

journal_title：Brain research bulletin

authors： Nottebohm F

更新日期：2002-04-01 00:00:00

abstract：:The expression of ErbB4 mRNA was examined in dorsal thalamic regions of chicks and rats. In rats, ErbB4 expression was observed in the habenular nuclei, the paraventricular nucleus, intermediodorsal nucleus, the central medial thalamic nucleus, the posterior nucleus, the parafascicular nucleus, the subparafascicular n...

journal_title：Brain research bulletin

authors： Bruce LL,Kornblum HI,Seroogy KB

更新日期：2002-02-01 00:00:00

abstract：:To investigate the effect of stimulus presentation rate on the activity of primary somatosensory cortex, we performed echo-planar functional magnetic resonance imaging using a 1.5-tesla magnetic resonance system. Eight right-handed normal volunteers underwent functional magnetic resonance imaging during somatosensory ...

journal_title：Brain research bulletin

authors： Takanashi M,Abe K,Yanagihara T,Oshiro Y,Watanabe Y,Tanaka H,Hirabuki N,Nakamura H,Fujita N

更新日期：2001-01-15 00:00:00

abstract：:Astrocytes become activated and proliferate in response to autoimmune diseases involving the CNS. In many cases, elevated numbers of astrocytes may compound inflammatory responses and exacerbate neuronal degeneration. The regulation of astrocytes in disease states has been shown as an important corollary to disease pr...

journal_title：Brain research bulletin

authors： Campbell AM,Zagon IS,McLaughlin PJ

更新日期：2013-01-01 00:00:00

abstract：:Cerebral ischemia is one of the leading causes of death and long-term disability worldwide. N-myc downstream-regulated gene 4 (NDRG4) is predominantly expressed in the brain as well as in the heart and has been reported to be involved in resistance to neuronal cell death caused by ischemic injury. However, the underly...

journal_title：Brain research bulletin

authors： Wen L,Liu L,Li J,Tong L,Zhang K,Zhang Q,Li C

更新日期：2019-03-01 00:00:00

abstract：:Spinal astrocytes have emerged as important mechanistic contributors to pathological and chronic pain. Recently, we have demonstrated that injection of diluted bee venom (DBV) into the Zusanli (ST36) acupoint produces a potent anti-nociceptive effect via the activation of spinal alpha-2 adrenoceptors. However, it is u...

journal_title：Brain research bulletin

authors： Kang SY,Kim CY,Roh DH,Yoon SY,Park JH,Lee HJ,Beitz AJ,Lee JH

更新日期：2011-11-25 00:00:00

abstract：:Astrocytes are key active elements of the brain that contribute to information processing. They not only provide neurons with metabolic and structural support, but also regulate neurogenesis and brain wiring. Furthermore, astrocytes modulate synaptic activity and plasticity in part by controlling the extracellular spa...

journal_title：Brain research bulletin

authors： Dossi E,Vasile F,Rouach N

更新日期：2018-01-01 00:00:00

abstract：:In pigeons, the tectofugal system is functionally as well as structurally lateralized. So for example the right nucleus rotundus is less modulated by right forebrain influences than the left nucleus rotundus by the left ones. This functional lateralization pattern may depend on a dynamic balance between left and right...

journal_title：Brain research bulletin

authors： Freund N,Güntürkün O,Manns M

更新日期：2008-03-18 00:00:00

abstract：:This study tested for the presence of androgen receptor-immunoreactivity in somatostatin, galanin, vasopressin, corticotropin-releasing hormone, and oxytocin neurons in the rat forebrain. The brains of adult male Sprague-Dawley rats were fixed with 4% paraformaldehyde. Androgen receptor was visualized in coronal secti...

journal_title：Brain research bulletin

authors： Bingaman EW,Baeckman LM,Yracheta JM,Handa RJ,Gray TS

更新日期：1994-01-01 00:00:00

abstract：:Although the huge economic and social impact and the predicted incidence increase, neuroprotection for ischemic stroke remains as a therapeutically empty niche. In the present study, we investigated the rationale of the C-Phycocyanin (C-PC) treatment on global cerebral ischemia/reperfusion (I/R) injury in gerbils. We ...

journal_title：Brain research bulletin

authors： Pentón-Rol G,Marín-Prida J,Pardo-Andreu G,Martínez-Sánchez G,Acosta-Medina EF,Valdivia-Acosta A,Lagumersindez-Denis N,Rodríguez-Jiménez E,Llópiz-Arzuaga A,López-Saura PA,Guillén-Nieto G,Pentón-Arias E

更新日期：2011-08-10 00:00:00