Transgenic mice expressing the human presenilin 1 gene demonstrate enhanced hippocampal reorganization following entorhinal cortex lesions.

abstract：:Recent investigations of the nucleus ambiguus (NA) have attempted to identify motoneurons associated with the branchiomeric muscles of the larynx and pharynx. However, relatively little attention has been directed to the levator veli palatini muscle (LVP) which is critical in respiration, deglutition and eustachian tu...

journal_title：Brain research bulletin

authors： van Loveren H,Saunders MC,Keller JT

更新日期：1983-09-01 00:00:00

abstract：:beta-Amyloid and related peptides are components of the neurofibrillary tangles found in the brains of patients with Alzheimer's disease and have been suggested to be directly involved in the pathophysiology of that condition. It is unclear whether the amyloid deposited in the brain arises from the peripheral circulat...

journal_title：Brain research bulletin

authors： Banks WA,Kastin AJ,Barrera CM,Maness LM

更新日期：1991-12-01 00:00:00

abstract：:Rats implanted with electrodes for polygraphic recording were deprived of REM sleep for 24 hr. Following REM sleep deprivation animals were injected with quipazine maleate (7.5 mg/kg IP) and were polygraphically recorded for 48 hr. The results show that quipazine reduces REM sleep rebound and that it has a biphasic ef...

journal_title：Brain research bulletin

authors： Zak R,Radulovacki M

更新日期：1982-03-01 00:00:00

abstract：:Cats pretreated with morphine (5 mg/kg, IP) received naloxone into the area of the locus coeruleus (LC) or the area of the substantia nigra (SN). The LC-treated animals stopped the morphine-induced stereotyped behavior and showed normal but hyperactive behavior. The SN-treated animals, however, ceased their movements ...

journal_title：Brain research bulletin

authors： van Dongen PA,Broekkamp CL,Cools AR

更新日期：1979-05-01 00:00:00

abstract：:Adaptation of the frog, Rana temporaria, to a white background for 12 hr has resulted in an intense formaldehyde-induced fluorescence (FIF) in the neurons of the preoptic recess organ (PRO), paraventricular organ (PVO), nucleus infundibularis dorsalis (NID) and their basal processes permitting visualization of the PRO...

journal_title：Brain research bulletin

authors： Prasada Rao PD

更新日期：1982-07-01 00:00:00

abstract：:Glaucoma is no longer viewed simply as elevated intraocular pressure (IOP) that damages the optic nerve. In addition to high IOP, evidence is rapidly accumulating that suggests damage to the optic nerve may be initiated or sustained by any number of factors including ischemia, excitotoxicity, neurotrophin insufficienc...

journal_title：Brain research bulletin

authors： Tezel G,Yang J,Wax MB

更新日期：2004-02-15 00:00:00

abstract：:Studies were conducted to determine if norepinephrine activates both protein kinase C and the cyclic AMP-dependent protein kinase in cultured rat astrocytes using phosphoproteins as markers. Norepinephrine was found to decrease 32P incorporation into an acidic 80,000 M(R) protein. A similar response was observed with ...

journal_title：Brain research bulletin

authors： Mobley PL,Combs DL

更新日期：1992-09-01 00:00:00

abstract：:Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had...

journal_title：Brain research bulletin

authors： Eisenman JS

更新日期：1983-06-01 00:00:00

abstract：:Previous studies using a pharmacological approach suggested a neural pathway emanating from the periaqueductal gray (PAG) to the nucleus accumbens relevant to antinociception. This was investigated with neurochemical and histochemical methods in the present study. Push-pull perfusion and radioimmunoassay were used to ...

journal_title：Brain research bulletin

authors： Ma QP,Han JS

更新日期：1992-06-01 00:00:00

abstract：:The Tac4 gene-derived hemokinin-1 (HK-1) is present in pain-related regions and activates the tachykinin NK1 receptor, but with binding site and signaling pathways different from Substance P (SP). NK1 receptor is involved in nociception, but our earlier data showed that it has no role in chronic neuropathic hyperalges...

journal_title：Brain research bulletin

authors： Hunyady Á,Hajna Z,Gubányi T,Scheich B,Kemény Á,Gaszner B,Borbély É,Helyes Z

更新日期：2019-04-01 00:00:00

abstract：:The olfactory bulbectomized (OBX) rat model of depression has been widely used in studies on the behavioral and neurochemical aspects of human depression. The objective of the present investigation was to assess open field (OF) activity and the brain regional 5-HT(1A) receptor densities of the sham operated (SHX) and ...

journal_title：Brain research bulletin

authors： Sato H,Skelin I,Debonnel G,Diksic M

更新日期：2008-03-28 00:00:00

abstract：:This paper surveys more than twenty types of tactile illusions and discusses several of their aspects. These aspects include the ease with which they can be demonstrated and whether they have clear visual analogs. The paper also shows how to construct equipment made of simple supplies able to deliver well-controlled t...

journal_title：Brain research bulletin

authors： Hayward V

更新日期：2008-04-15 00:00:00

abstract：:Ghrelin (Ghr) has two main forms in the blood: the acylated (A-Ghr) and non-acylated (NA-Ghr) Ghr. A-Ghr was discovered as a potent growth hormone (GH) secretion increasing substance acting on GH secretagouge receptor (GHS-R) type 1a. A-Ghr facilitates food intake after its i.p., i.c.v. or direct hypothalamic applicat...

journal_title：Brain research bulletin

authors： Tóth K,László K,Bagi EE,Lukács E,Lénárd L

更新日期：2008-09-30 00:00:00

abstract：:Administering increasing dosages of 5alpha-dihydrotestosterone propionate (DHTP) (0, 40, or 80 microgram/100 g in oil daily) to ovariectomized female rats treated concurrently with estradiol benzoate (EB) (1 microgram/100 g in oil daily) caused significant, equivalent reduction in lordotic responsiveness in rats maint...

journal_title：Brain research bulletin

authors： Menniti FS,Erskine MS,Baum MJ

更新日期：1981-07-01 00:00:00

abstract：:Locomotor activity was increased as a function of current intensity in a series of rats with chronic stimulating electrodes in the tegmental pedunculopontine nucleus. Single pulse stimulation of these same mesencephalic locomotor region (MLR) sites antidromically activated more than one-quarter of the neurons sampled ...

journal_title：Brain research bulletin

authors： Mogenson GJ,Wu M

更新日期：1986-03-01 00:00:00

abstract：:Crested Ducks (CR) occasionally show intracranial fat bodies. Additionally, behavioral abnormalities such as motor incoordination can be observed. Here, it is shown that a behavioral test helps to identify CR that have a problematical fat body. The ducks were put on their backs, and the time required for them to stand...

journal_title：Brain research bulletin

authors： Cnotka J,Tiemann I,Frahm HD,Rehkämper G

更新日期：2008-06-15 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people over 60 years of age in the US and many other developed countries. Increasingly sophisticated methods for the diagnosis and treatment of macular degeneration are not effective for the majority of patients in whom late stage...

journal_title：Brain research bulletin

authors： Rowe-Rendleman C,Glickman RD

更新日期：2004-02-15 00:00:00

abstract：:Regenerative medicine strategies rely on exogenous cell transplantation and/or endogenous cell stimulation. Biomaterials can help to increase the regenerative potential of cells and biomolecules by controlling transplanted cell fate and provide a local, sustained release of biomolecules. In this review, we describe th...

journal_title：Brain research bulletin

authors： Ho MT,Teal CJ,Shoichet MS

更新日期：2019-05-01 00:00:00

abstract：:A simple low-cost modification to a conventional horizontal two-stage micropipette puller is described. It allows the production of pipettes suitable for patch-clamp studies. It requires that the hard-pull stage of the fabrication process be disabled and two heating cycles, each with a different heating filament tempe...

journal_title：Brain research bulletin

authors： Mealing GA,Schwartz JL

更新日期：1989-05-01 00:00:00

abstract：:Several hypotheses have been proposed to explain why some neurological patients fail to recognise objects from unusual views: that it results from difficulty identifying an object's principal axis when it is foreshortened, identifying an object when landmark features are occluded, or an inability to rotate mental imag...

journal_title：Brain research bulletin

authors： Turnbull OH,McCarthy RA

更新日期：1996-01-01 00:00:00

abstract：:The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson's disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exact molecular mechani...

journal_title：Brain research bulletin

authors： Anandhan A,Jacome MS,Lei S,Hernandez-Franco P,Pappa A,Panayiotidis MI,Powers R,Franco R

更新日期：2017-07-01 00:00:00

abstract：:This study aims to evaluate the neuroprotective effect of sodium butyrate against the pentylenetetrazol (PTZ)-induced kindling epilepsy. Sodium butyrate (SB) (5, 10 and 20 mg/kg) and sodium valproate for 40 days and PTZ (37 mg/kg) injection every day were conducted for Kunming mice, to investigate seizure intensity an...

journal_title：Brain research bulletin

authors： Li D,Bai X,Jiang Y,Cheng Y

更新日期：2020-12-28 00:00:00

abstract：:The effects of chemically and electrically-induced convulsions on the binding of [3H]Ro 5-4864 to peripheral benzodiazepine receptors (PBR) was studied in both peripheral tissues and the central nervous system (CNS). Acute, maximal electroshock (MES) increased the density of PBR in mouse cerebral cortex as evidenced b...

journal_title：Brain research bulletin

authors： Basile AS,Weissman BA,Skolnick P

更新日期：1987-07-01 00:00:00

abstract：:GnRH release from hypothalamic explants from young and aged male Wistar-Kyoto rats was evaluated following stimulation with glutamate receptor agonists. Glutamate stimulated GnRH release to a similar extent in hypothalami from young and old animals, whereas N-methyl-D-Aspartate (NMDA) and kainate appeared more efficac...

journal_title：Brain research bulletin

authors： Sortino MA,Aleppo G,Scapagnini U,Canonico PL

更新日期：1996-01-01 00:00:00

abstract：:We studied levels of mRNA for the alpha- and beta-subunits of calmodulin (CaM) kinase II using the amygdaloid kindling model of epilepsy. There were significant increases in mRNA for the beta-subunit of CaM kinase II in the hippocampus 4-24 h after stage 5-kindled seizures. Moreover, this mRNA was significantly increa...

journal_title：Brain research bulletin

authors： Morimoto K,Sato K,Kashihara K,Hayabara T

更新日期：1997-01-01 00:00:00

abstract：:Cultures of endothelial cells (EC) derived from human (autopsy) and canine brain microvessels were characterized with respect to growth, morphology, and biochemical features. The endothelial nature of these cells was confirmed by analyses of angiotensin-converting enzyme activity, Factor VIII-related antigen, and ultr...

journal_title：Brain research bulletin

authors： Gerhart DZ,Broderius MA,Drewes LR

更新日期：1988-11-01 00:00:00

abstract：:Many objective and quantitative methods have been developed to create a procedure or a device to prove, describe and quantify olfactory deficit and anosmia, especially after a head trauma. Electrophysiological testing throughout olfactoelectroencephalography (olfactoEEG) is based on brain activity desynchronisation, a...

journal_title：Brain research bulletin

authors： Bonanni E,Borghetti D,Fabbrini M,Maestri M,Cignoni F,Sartucci F,Murri L

更新日期：2006-12-11 00:00:00

abstract：:Polymerase chain reaction assays are a powerful tool for detecting the presence of infectious genomes in the cerebrospinal fluid. Positive results always mean a current or pending infection of the central nervous system. Subacute (>7 days) or chronic infections induce an intrathecal humoral immune response and the app...

journal_title：Brain research bulletin

authors： Sindic CJ,Van Antwerpen MP,Goffette S

更新日期：2003-08-15 00:00:00

abstract：:Extracellular recordings were made from 467 anti-dromically identified neurosecretory neurons and 148 non-neurosecretory neurons in the paraventricular nucleus of the hypothalamus of hemispherectomized cats under pentobarbital anesthesia. Stimulation of the dorsal, median, and pontine raphe nuclei excited 31%, 26%, an...

journal_title：Brain research bulletin

authors： Kawano S,Osaka T,Kannan H,Yamashita H

更新日期：1992-04-01 00:00:00

abstract：:The availability of mutant mice that lack either MAO A or MAO B has created unique profiles in the central and peripheral availability of serotonin, norepinephrine, dopamine, and phenylethylamine. This paper summarizes some of the current known phenotypic findings in MAO A knock-out mice and contrast these with those ...

journal_title：Brain research bulletin

authors： Holschneider DP,Chen K,Seif I,Shih JC

更新日期：2001-11-15 00:00:00