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Biochemical, behavioral, physiologic, and neurodevelopmental changes in mice deficient in monoamine oxidase A or B.

Abstract：

:The availability of mutant mice that lack either MAO A or MAO B has created unique profiles in the central and peripheral availability of serotonin, norepinephrine, dopamine, and phenylethylamine. This paper summarizes some of the current known phenotypic findings in MAO A knock-out mice and contrast these with those of MAO B knock-out mice. Differences are discussed in relation to the biochemical, behavioral, and physiologic changes investigated to date, as well as the role played by redundancy mechanisms, adaptational responses, and alterations in neurodevelopment.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Holschneider DP,Chen K,Seif I,Shih JC

doi

10.1016/s0361-9230(01)00613-x

keywords:

subject

Has Abstract

pub_date

2001-11-15 00:00:00

pages

453-62

issue

5

eissn

0361-9230

issn

1873-2747

pii

S0361-9230(01)00613-X

journal_volume

56

pub_type

杂志文章,评审

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