Different responses of gonadotropin-releasing hormone (GnRH) release to glutamate receptor agonists during aging.

abstract：:Central administration of the tachykinins, eledoisin or physalaemin has been reported to produce significant water intake in pigeons but inhibition of stimulated drinking in rats. In this paper it is shown that high and low doses of these two tachykinins injected centrally in two much larger species, goats and pigs, d...

journal_title：Brain research bulletin

authors： Thornton SN,Baldwin BA

更新日期：1990-07-01 00:00:00

abstract：:Single unit recordings were used to map the spatial distribution of motor (MI) cortical influences on thalamic somatosensory relay nuclei in the rat. A total of 215 microelectrode penetrations were made to record single neurons in tracks through the medial and lateral ventroposterior (VPM and VPL), ventrolateral (VL),...

journal_title：Brain research bulletin

authors： Shin HC,Chapin JK

更新日期：1990-02-01 00:00:00

abstract：:Somatostatin immunoreactive (SOM-I) perikarya were first observed in the ventral horn at E12, in the presumptive intermediate gray area at E14, and in the alar plate of the rostral spinal cord at E14. In general, after their initial appearance, their density increased and then decreased during development. A moderate ...

journal_title：Brain research bulletin

authors： Ho RH

更新日期：1988-07-01 00:00:00

abstract：:Locomotor activity was increased as a function of current intensity in a series of rats with chronic stimulating electrodes in the tegmental pedunculopontine nucleus. Single pulse stimulation of these same mesencephalic locomotor region (MLR) sites antidromically activated more than one-quarter of the neurons sampled ...

journal_title：Brain research bulletin

authors： Mogenson GJ,Wu M

更新日期：1986-03-01 00:00:00

abstract：:In order to study mechanisms by which a neurotropic strain of influenza A virus (A/WSN/33) may affect neuronal function or cause nerve cell death, hippocampal cultures from embryonic rats were infected with this virus. Approximately 70% of the neurons in the infected cultures became immunopositive for viral antigens a...

journal_title：Brain research bulletin

authors： Brask J,Owe-Larsson B,Hill RH,Kristensson K

更新日期：2001-06-01 00:00:00

abstract：:One of the important factors altering the degree of blood-brain barrier (BBB) disruption in cerebral ischemia is the anesthetic used. The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway has been reported to be involved in modulating BBB permeability and in isoflurane induced neuroprotection. This study was perf...

journal_title：Brain research bulletin

authors： Chi OZ,Mellender SJ,Kiss GK,Liu X,Weiss HR

更新日期：2017-05-01 00:00:00

abstract：:Neuroimaging studies in patients suffering from affective disorders have shown decreased volume and reduced regional cerebral blood flow in multiple areas of the prefrontal cortex, including the medial prefrontal cortex and the orbitofrontal cortex. This aberrant brain activity is among other things attributed to chro...

journal_title：Brain research bulletin

authors： Gerrits M,Westenbroek C,Fokkema DS,Jongsma ME,Den Boer JA,Ter Horst GJ

更新日期：2003-10-15 00:00:00

abstract：:It is well known that some epileptic patients does not respond to conventional treatments, despite multiple combination of antiepileptic drugs, and they are therefore considered drug-resistant. For these patients, vagal nerve stimulation (VNS) represents a successful alternative to traditional therapy, and it is gener...

journal_title：Brain research bulletin

authors： Borghetti D,Pizzanelli C,Maritato P,Fabbrini M,Jensen S,Iudice A,Murri L,Sartucci F

更新日期：2007-06-15 00:00:00

abstract：:Trisomy of the whole or distal part of human chromosome 21 (HSA 21) (Ts21) results in Down Syndrome (DS), which is characterized in part by mental retardation and associated neurological abnormalities. Structural abnormalities observed frequently include reduced brain weight, decreased number and depth of sulci in the...

journal_title：Brain research bulletin

authors： Coyle JT,Oster-Granite ML,Gearhart JD

更新日期：1986-06-01 00:00:00

abstract：:Mouse models that replicate facets of human neurological diseases are often used at the pre-clinical stage to better understand the underlying mechanisms of a disease and test the target engagement of potential therapeutic interventions. We recently characterized a mouse model of childhood-onset parkinsonism-dystonia,...

journal_title：Brain research bulletin

authors： Giraldo G,Janus C

更新日期：2021-01-01 00:00:00

abstract：:Early life Stress is a worldwide concern linked with development of later life neurological disorders. Early developmental age is sensitive to many prominent environmental insults like malnourishment, immune inflammation, abuse, maternal separation, alcohol and drugs. Hence, an individual during an early age encounter...

journal_title：Brain research bulletin

authors： Sarkar T,Patro N,Patro IK

更新日期：2019-04-01 00:00:00

abstract：:Entrainment of the dominant circadian pacemaker localised to the hypothalamic suprachiasmatic nuclei (SCN) is mediated partially via the indirect retino-geniculo-hypothalamic projection to the SCN, which is presumed to utilise enkephalin and other neurotransmitters, to modulate circadian rhythmicity. In the present st...

journal_title：Brain research bulletin

authors： Cutler DJ,Mundey MK,Mason R

更新日期：1999-09-15 00:00:00

abstract：:When applied by iontophoresis onto single sympathetic preganglionic neurones in the intermediolateral nucleus of segments T1-T3 in the cat, oxytocin and vasopressin each had an excitatory effect. This effect consisted of a prolonged (30-300 sec) after-discharge following termination of application. These results indic...

journal_title：Brain research bulletin

authors： Backman SB,Henry JL

更新日期：1984-11-01 00:00:00

abstract：:We examined whether reticulospinal sympathoexcitatory neurons in the rostral ventrolateral medulla (RVLM) have muscarinic receptors and ACh inputs, and whether these cholinergic mechanisms on RVLM neurons are involved in the pressor response induced by peripheral administration of physostigmine. Microiontophoretic app...

journal_title：Brain research bulletin

authors： Kubo T,Taguchi K,Sawai N,Ozaki S,Hagiwara Y

更新日期：1997-01-01 00:00:00

abstract：:Tetramethylrhodamine-dextran is a highly fluorescent neuroanatomical tracer that, in its 10,000 MW form, has seen widespread use as a sensitive anterograde tract-tracing label. We report here the use of a lower molecular weight tetramethylrhodamine-dextran (3000 MW; Molecular Probes, OR) as an in vivo intracellular ma...

journal_title：Brain research bulletin

authors： Carr PA,Noga BR,Nance DM,Jordan LM

更新日期：1994-01-01 00:00:00

abstract：:Under standard laboratory conditions rats given access to three separate macronutrient sources compose a diet yielding 31% of their total daily calories as protein, 34% as carbohydrate, and 34% as fat. This selection pattern is dramatically altered with restored access following a 48 h fast. During the first hour of r...

journal_title：Brain research bulletin

authors： Bernardini J,Kamara K,Castonguay TW

更新日期：1993-01-01 00:00:00

abstract：:The labelling of hypothalamic binding sites by [125I]-FK, a specific mu-opioid receptor ligand, was studied in female C57BL/6J mice to test whether removal of ovarian steroids affected the density of distribution of receptor binding. Labelling densities in the forebrain of normally cycling (intact) females (N = 12), w...

journal_title：Brain research bulletin

authors： Joshi D,Billiar RB,Miller MM

更新日期：1993-01-01 00:00:00

abstract：:IN anesthetized and paralyzed rabbits, action potentials were elicited antidromically following electrical stimulation of optic tract terminals at the geniculate level (LGN). The conduction velocity spectrum extended from 7 m.s-1 to 34 m.s-1. The distribution of conduction velocities indicated four major modes at 10, ...

journal_title：Brain research bulletin

authors： Molotchnikoff S,Lessard I

更新日期：1980-11-01 00:00:00

abstract：:Calcium/calmodulin-dependent protein-kinase II (CaMKII) is a ubiquitous intracellular enzyme, which is implicated in learning and memory mechanisms in the central nervous system, however its contribution to peripheral cholinergic neurotransmission is not well characterized. This study evaluated the impact of CaMKII on...

journal_title：Brain research bulletin

authors： Mukhamedyarov MA,Kochunova JO,Yusupova ER,Haidarov BA,Zefirov AL,Palotás A

更新日期：2010-04-05 00:00:00

abstract：:In experimental studies on peripheral nerve repair, the possibility to objectively compare original and post-operative innervation is of decisive importance for the selection of the proper nerve-reconstruction strategy. Herewith we report serious drawbacks encountered with the standard method of pre- and post-operativ...

journal_title：Brain research bulletin

authors： Popratiloff AS,Neiss WF,Skouras E,Streppel M,Guntinas-Lichius O,Angelov DN

更新日期：2001-01-01 00:00:00

abstract：:A recent in vitro electrophysiological analysis combined with anatomical approach suggests that a potential disinhibitory mechanism involving somatostatin (SST), which is released by interneurons in the superficial dorsal horn, contributes to nociceptive transmission (Yasaka et al., 2010); however, whether this mechan...

journal_title：Brain research bulletin

authors： Takahashi M,Takeda M,Matsumoto S

更新日期：2014-01-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSCs) are involved in cancer initiation and metastasis, and sometimes mediate cell communication by releasing exosomes and delivering microRNAs (miRNAs). The study aims to investigate the effects of exosomal hsa-miR-23b-3p derived from human BMSCs on intracranial aneurysm (IA). Fir...

journal_title：Brain research bulletin

authors： Sun X,Zheng X,Zhang X,Zhang Y,Luo G

更新日期：2020-12-01 00:00:00

abstract：:Chronic cerebral hypofusion (CCH) after bilateral carotid artery occlusion (2VO) causes cognitive damage and neuronal degeneration in the cortex and hippocampal CA1 area, and influences the oxygen and glucose supply in the brain which often results in metabolic alterations and oxidative stress. AMP-activated protein k...

journal_title：Brain research bulletin

authors： Chen Y,Guo Z,Peng X,Xie W,Chen L,Tan Z

更新日期：2018-06-01 00:00:00

abstract：:Catecholaminergic systems, specifically in the region of the lateral perifornical hypothalamus (PFH), have been linked to the inhibition of feeding behavior. The present studies examined the effects of d-amphetamine (AMPH), which is believed to act through the release of endogenous catecholamines (CAs), on spontaneous...

journal_title：Brain research bulletin

authors： Leibowitz SF,Shor-Posner G,Maclow C,Grinker JA

更新日期：1986-11-01 00:00:00

abstract：:The effect of pretreatment of geranylgeranylacetone (GGA), an inducer of heat shock protein (HSP) 70, on responses in sleep and core body temperature (Tcore) against sleep deprivation (SD) was examined in rats. After 3 days of GGA or vehicle injection, a 6-h period of SD was performed. During the recovery period, both...

journal_title：Brain research bulletin

authors： Wada T,Sei H,Kusumoto K,Kitaoka K,Chikahisa S,Rokutan K,Morita Y

更新日期：2006-04-28 00:00:00

abstract：OBJECTIVE:To explore the unified and disease specific structural features of the brain in patients spanning six mental disorders who experience own-thought auditory verbal hallucinations (OTAVH). METHODS:A pilot study was conducted on 25 patients with schizophrenia (FUSCH-OTAVH), 20 patients with major depression diso...

journal_title：Brain research bulletin

authors： Zhuo C,Lin X,Wang C,Song X,Xu X,Li G,Xu Y,Tian H,Zhang Y,Wang W,Zhou C

更新日期：2020-07-01 00:00:00

abstract：:Cell-free incorporation of (14C) leucine into protein was 38% greater for cerebral cortical microsomes from 22-day old neonatally thyroidectomized rats compared to littermate controls. In contrast, incorporation by liver microsomes of hypothyroid rats was 33% lower compared to controls, confirming their deficient horm...

journal_title：Brain research bulletin

authors： Gonzales LW,Geel SE

更新日期：1980-01-01 00:00:00

abstract：:Endogenous adrenergic drive regulates the firing rate of serotonergic neurons. However, advocates of feedback theory assert that 5-hydroxytryptamine (5-HT) released in the somatodendritic region of raphe neurons regulates both rate and release of 5-HT. Experiments were done to determine if the somatodendritic region m...

journal_title：Brain research bulletin

authors： Kalsner S,Abdali SA

更新日期：2001-08-01 00:00:00

abstract：:Plasma gonadotropins, prolactin and hypothalamic tyrosine hydroxylase (TH) activity were evaluated at 15 and 30 min after third ventricular injection of bombesin at doses of 100 or 1000 ng and secretin at doses of 1000 and 5000 ng in ovariectomized (OVX) unanesthetized rats. Bombesin had no effect on plasma gonadotrop...

journal_title：Brain research bulletin

authors： Babu GN,Vijayan E

更新日期：1983-07-01 00:00:00

abstract：:Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valua...

journal_title：Brain research bulletin

authors： Arendt T,Stieler JT,Holzer M

更新日期：2016-09-01 00:00:00