Misexpression of miR-196a induces eye anomaly in Xenopus laevis.

abstract：:Interleukin-33 (IL-33) is closely related to the regulation of immunological cells, and its receptor ST2 is a member of the interleukin-1 (IL-1) receptor family. Inflammatory responses play critical roles in neuronal damage and white matter injury (WMI) post intracerebral hemorrhage (ICH). In this study, we tried to e...

journal_title：Brain research bulletin

authors： Chen Z,Xu N,Dai X,Zhao C,Wu X,Shankar S,Huang H,Wang Z

更新日期：2019-08-01 00:00:00

abstract：:Previously obtained data suggests that noradrenaline (NE) released from the efferent locus coeruleus (LC) endings in hippocampal formation (HPC) may serve as an important modulating signal involved in the pharmacological mechanisms responsible for the production of type 2 theta rhythm in rats. Hence, two distinct hypo...

journal_title：Brain research bulletin

authors： Broncel A,Bocian R,Kłos-Wojtczak P,Konopacki J

更新日期：2020-09-01 00:00:00

abstract：:In eleven acute precollicular rats, cortical and hippocampal EEG activity was recorded. Hippocampal theta activity of low frequency (mean 4.5 c/sec) was found in nine rats and in four occupied above 50% of the recording time. In contrast, in the cortex the synchronized EEG activity dominated. The electrical stimulatio...

journal_title：Brain research bulletin

authors： Gottesmann C,Gandolfo G,Zernicki B

更新日期：1989-06-01 00:00:00

abstract：:Various reports have suggested that penehyclidine hydrochloride (PHC), a new cholinergic antagonist, exhibits a variety of biological actions such as anti-tumor and cardioprotective effects. This study aimed to investigate the effects of PHC on cerebral ischemia/reperfusion (I/R) injury and evaluate whether the c-Jun ...

journal_title：Brain research bulletin

authors： Shu Y,Yang Y,Zhang P

更新日期：2016-03-01 00:00:00

abstract：:Using microdialysis, the effects of endogenous dopamine on basal extracellular concentrations of gamma-aminobutyric acid (GABA) and on the increases of GABA produced by glutamate were investigated in the medial prefrontal cortex of the awake rat. The dopamine uptake inhibitor nomifensine (1, 100 and 1000 microM), used...

journal_title：Brain research bulletin

authors： Del Arco A,Mora F

更新日期：2000-10-01 00:00:00

abstract：:In the preceding article, a dorsochiasmatic area (DCh) was described that projects to both paraventricular (PVN) and supraoptic (SON) nuclei. The main afferents of the DCh, revealed by local injections of retrograde tracers, are the hypothalamic PVN and SON, lateral septal nuclei (LSV and SHy), bed nuclei of the stria...

journal_title：Brain research bulletin

authors： Thellier D,Moos F,Richard P,Stoeckel ME

更新日期：1994-01-01 00:00:00

abstract：:Fenfluramine, an anorexigenic drug, lowers serotonin (5-hydroxytryptamine) and 5-hydroxyindoleacetic acid levels in brain, spinal fluid, and blood, and has been used as a treatment for autism. Fenfluramine's mode of action is unknown. We present evidence from chromatography and nuclear magnetic resonance spectroscopy ...

journal_title：Brain research bulletin

authors： Root-Bernstein RS,Westall FC

更新日期：1984-01-01 00:00:00

abstract：:Patients with post-traumatic stress disorder (PTSD) tend to misinterpret innocuous stimuli as potential threats, possibly due to a conditioning provoked by traumatic episodes. Previous neuroimaging evidence has shown an abnormal activation of the amygdala and prefrontal cortex in PTSD patients during fear conditioning...

journal_title：Brain research bulletin

authors： Brunetti M,Sepede G,Ferretti A,Mingoia G,Romani GL,Babiloni C

更新日期：2015-05-01 00:00:00

abstract：:Gamma-secretase (GS) is an enzyme complex that cleaves numerous substrates, and it is best known for cleaving amyloid precursor protein (APP) to form amyloid-beta (Aβ) peptides. Aberrant cleavage of APP can lead to Alzheimer's disease, so much research has been done to better understand GS structure and function in ho...

journal_title：Brain research bulletin

authors： Carroll CM,Li YM

更新日期：2016-09-01 00:00:00

abstract：:Tetramethylrhodamine-dextran is a highly fluorescent neuroanatomical tracer that, in its 10,000 MW form, has seen widespread use as a sensitive anterograde tract-tracing label. We report here the use of a lower molecular weight tetramethylrhodamine-dextran (3000 MW; Molecular Probes, OR) as an in vivo intracellular ma...

journal_title：Brain research bulletin

authors： Carr PA,Noga BR,Nance DM,Jordan LM

更新日期：1994-01-01 00:00:00

abstract：:The periventricular tissue surrounding the anteroventral third ventricle (AV3V) is critically involved in the maintenance of normal body fluid balance and distribution. The present review examines the anatomical, neurochemical, and functional relationship of the AV3V with neural systems subserving body fluid homeostas...

journal_title：Brain research bulletin

authors： Johnson AK

更新日期：1985-12-01 00:00:00

abstract：:The nucleus locus coeruleus (LC) has been implicated in the modulation of the spinal sensorimotor function. The aim of the present study was to examine the effect of electrical stimulation of the LC on sensorimotor function in the trigeminal system. The following two cases of sensorimotor behaviors mediated by the tri...

journal_title：Brain research bulletin

authors： Matsutani K,Tsuruoka M,Shinya A,Furuya R,Kawawa T

更新日期：2000-12-01 00:00:00

abstract：:Intrathecal grafting of cells as biological pumps to deliver monoamines, endorphins, and/or trophic factors, has been shown to be effective in treating chronic pain both in experimental animals and in clinical trials. We have tested whether intrathecal implantation of neuroblastoma cells reduces heat hyperalgesia and ...

journal_title：Brain research bulletin

authors： De la Calle JL,Mena MA,González-Escalada JR,Paíno CL

更新日期：2002-11-30 00:00:00

abstract：:Patterns of female sexual behavior in the hamster are qualitatively different from that observed in the rat. Hamsters demonstrate tonic immobility and a sustained lordotic response that can last for several minutes following minimal stimulation from the male while in rats, the lordotic response is highly dependent upo...

journal_title：Brain research bulletin

authors： Nance DM,Myatt GA

更新日期：1987-12-01 00:00:00

abstract：:The effects of intracarotidly injected neuropeptide Y (NPY; 0.1 micrograms/kg) on the local cerebral blood volume (CBV) and blood flow (CBF) in the parieto-temporal cortex were examined by the photoelectric method in 17 anesthetized cats. CBV reflects the cumulative crosssectional area of the cerebral microvascular be...

journal_title：Brain research bulletin

authors： Kobari M,Fukuuchi Y,Tomita M,Tanahashi N,Yamawaki T,Takeda H,Matsuoka S

更新日期：1993-01-01 00:00:00

abstract：:The non-adenosine nucleoside guanosine (Guo) was demonstrated to decrease quinolinic acid(QA)-induced seizures, spontaneously emerged absence epileptic seizures and lipopolysaccharide(LPS)-evoked induction of absence epileptic seizures suggesting its antiepileptic potential. It was also described previously that intra...

journal_title：Brain research bulletin

authors： Lakatos RK,Dobolyi Á,Todorov MI,Kékesi KA,Juhász G,Aleksza M,Kovács Z

更新日期：2016-06-01 00:00:00

abstract：:The effects of electrical stimulation of the "mesencephalic locomotor region" and adjacent dorsolateral tegmentum were assessed and compared in the same rats in freely moving conditions or when lightly anesthetized and suspended over a moving treadmill. In freely moving conditions, electrical brain stimulation (EBS) o...

journal_title：Brain research bulletin

authors： Depoortere R,Di Scala G,Sandner G

更新日期：1990-11-01 00:00:00

abstract：:Cerebral malaria (CM) is the severe neurological complication associated with Plasmodium falciparum infection. In clinical settings CM is predominantly characterized by fever, epileptic seizures, and asexual forms of parasite on blood smears, coma and even death. Cognitive impairment in the children and adults even af...

journal_title：Brain research bulletin

authors： Vanka R,Nakka VP,Kumar SP,Baruah UK,Babu PP

更新日期：2020-04-01 00:00:00

abstract：:Two experiments examined the effects of the alpha-2 antagonist L657,743 on monkey electroencephalographic (EEG) and event-related potential (ERP) activity following auditory and visual stimuli. In the first experiment, EEG was recorded before and after the administration of a saline placebo or L657,743 (0.01, 0.05 mg/...

journal_title：Brain research bulletin

authors： Pineda JA,Westerfield M

更新日期：1993-01-01 00:00:00

abstract：:The neuropathology of Alzheimer disease is characterized by senile plaques, neurofibrillary tangles and cell death. These hallmarks develop according to the differential vulnerability of brain networks, senile plaques accumulating preferentially in the associative cortical areas and neurofibrillary tangles in the ento...

journal_title：Brain research bulletin

authors： Savioz A,Leuba G,Vallet PG,Walzer C

更新日期：2009-10-28 00:00:00

abstract：:Fetal ventromedial hypothalamic (VMH) tissue was transplanted into or around the third ventricle of adult Fischer 344 rats to determine if transplanted VMH tissue could reverse the hyperphagia and obesity produced by bilateral VMH electrolytic lesions. Host VMH-lesioned rats received stereotaxic implants of 13 to 19 p...

journal_title：Brain research bulletin

authors： Ono K,Kawamura K,Shimizu N,Ito C,Plata-Salamán CR,Ogawa N,Oomura Y

更新日期：1990-01-01 00:00:00

abstract：:Fluoro-Ruby (tetramethylrhodamine-dextran amine conjugate) has been shown recently to be an effective anterograde tracer readily visible in brain sections with fluorescence microscopy. We show in this study that further microscopic analysis of Fluoro-Ruby-labeled elements is feasible with a conventional immunoperoxida...

journal_title：Brain research bulletin

authors： Chang HT

更新日期：1993-01-01 00:00:00

abstract：:Glaucoma is no longer viewed simply as elevated intraocular pressure (IOP) that damages the optic nerve. In addition to high IOP, evidence is rapidly accumulating that suggests damage to the optic nerve may be initiated or sustained by any number of factors including ischemia, excitotoxicity, neurotrophin insufficienc...

journal_title：Brain research bulletin

authors： Tezel G,Yang J,Wax MB

更新日期：2004-02-15 00:00:00

abstract：:Neurological assessment of certain movement disorders is described with emphasis on Parkinson's disease. In addition, abnormal behavior and changes in affect are given. Changes in neurological status, i.e., Bradykinesia, rigidity, gait changes, hand-writing irregularity, postural reflexes are outlined. The differentia...

journal_title：Brain research bulletin

authors： Byer JA,Dexter JD

更新日期：1983-08-01 00:00:00

abstract：:Cell replacement therapy is of great interest as a long-term treatment of neurodegenerative diseases such as Parkinson's disease (PD). We have previously shown that Sertoli cells (SC) provide neurotrophic support to transplants of dopaminergic fetal neurons and NT2N neurons, derived from the human clonal precursors ce...

journal_title：Brain research bulletin

authors： Saporta S,Willing AE,Shamekh R,Bickford P,Paredes D,Cameron DF

更新日期：2004-12-15 00:00:00

abstract：:We previously reported that a low threshold action of norepinephrine (NE) on the cerebellar circuitry is expressed as an amplification of the inhibitory action of gamma aminobutyric acid (GABA) on Purkinje cell activity. Here we examined the effects of locus coeruleus (LC) stimulation on "off-beam" inhibitions of Purk...

journal_title：Brain research bulletin

authors： Moises HC,Waterhouse BD,Woodward DJ

更新日期：1983-06-01 00:00:00

abstract：:Subcutaneous melittin injection causes central plasticity at the spinal level in wide-dynamic-range (WDR) neurons, which are hypersensitive to various nociceptive stimuli. Previous behavioral studies demonstrated that the mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinase 1/2(ERK1/2), p38 ...

journal_title：Brain research bulletin

authors： Li MM,Yu YQ,Fu H,Xie F,Xu LX,Chen J

更新日期：2008-11-25 00:00:00

abstract：:The presence of intrinsic neurons in the hypothalamus containing the enzyme phenylethanolamine N-methyltransferase (PNMT), was investigated by selective destruction of the local cell bodies with kainic acid (KA), a potent excitotoxin. The unilateral stereotaxic injection of 2 micrograms of KA into the lateral hypothal...

journal_title：Brain research bulletin

authors： Masana MI,Mefford IN

更新日期：1989-12-01 00:00:00

abstract：:Progressive disruption of both the neuroendocrine and immune systems has been correlated with age-associated pathogenesis in patients with Alzheimer's disease and in mice lacking apolipoprotein E (ApoE). In this study, we examined neuroautoimmune and neuroendocrine activities in relation to aging and stress in ApoE-de...

journal_title：Brain research bulletin

authors： Zhou Y,Cheshire A,Howell LA,Ryan DH,Harris RB

更新日期：1999-06-01 00:00:00

abstract：:A number of biological risk factors have been implicated for Alzheimer's disease (AD). The investigation of prevalence rates of AD in crosscultural populations has much potential in validating these factors. We previously assessed brain amyloid beta (A beta) protein deposition and other lesions associated with AD as p...

journal_title：Brain research bulletin

authors： Kalaria RN,Ogeng'o JA,Patel NB,Sayi JG,Kitinya JN,Chande HM,Matuja WB,Mtui EP,Kimani JK,Premkumar DR,Koss E,Gatere S,Friedland RP

更新日期：1997-01-01 00:00:00