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Clinical evaluation of 430 MHz microwave hyperthermia system with lens applicator for cancer therapy.

Abstract：

:The clinical efficacy of a microwave (MW) hyperthermia system using an electric-field converging (lens) applicator is evaluated for 42 malignant tumours with a maximum tumour depth of less than 7 cm. The mean of the maximum, average and minimum tumour temperature of the 42 tumours are 44.5, 42.5 and 40.7 C, respectively. The thermal parameters are higher for tumours in the chest, abdominal walls and hip than for those in the neck, groin and extremities. No apparent difference in thermal parameters according to the depth of tumour is shown. Of 40 tumours treated by hyperthermia in combination with radiotherapy, 20 (50%) showed complete regression, 14 (35%) showed partial regression, and six (15%) showed no change. This phase I and II study indicates clinical feasibility of the newly developed MW heating apparatus, and strongly suggests the usefulness of thermoradiotherapy in the treatment of localised superficial and subsurface malignancies.

journal_name

Med Biol Eng Comput

journal_title

Medical & biological engineering & computing

authors

Hiraoka M,Nishimura Y,Masunaga S,Koishi M,Mitsumori M,Li YP,Nagata Y,Akuta K,Takahashi M,Abe M

doi

10.1007/BF02522944

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

44-7

issue

1

eissn

0140-0118

issn

1741-0444

journal_volume

33

pub_type

临床试验,杂志文章

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