Modulation of the nicotinic acetylcholine receptor channels by spermine in Xenopus muscle cell culture.

abstract：:Stimulation of murine primary microglia with Toll-like receptor (TLR) agonists enhances their ability to phagocytose and kill bacteria. Here we show that the viral TLR3 agonist poly(I:C) stimulates the release of cyto-/chemokines and nitric oxide by microglia. Poly(I:C) increases microglial phagocytosis and intracellu...

journal_title：Neuroscience letters

authors： Ribes S,Adam N,Ebert S,Regen T,Bunkowski S,Hanisch UK,Nau R

更新日期：2010-09-20 00:00:00

abstract：:This study investigated the effects of dementia on standing postural adaptation during performance of a visual search task. We recruited 16 older adults with dementia and 15 without dementia. Postural sway was assessed by recording medial-lateral (ML) and anterior-posterior (AP) center-of-pressure when standing with a...

journal_title：Neuroscience letters

authors： Jor'dan AJ,McCarten JR,Rottunda S,Stoffregen TA,Manor B,Wade MG

更新日期：2015-04-23 00:00:00

abstract：:A procedure for dissociating viable taste cells from the rodent tongue was described. After the tongue was excised, the foliate and circumvallate papillae from the posterior region were blocked to small pieces and incubated for 2-3 h in a calcium-free salt solution containing the enzyme papain. The pieces were then tr...

journal_title：Neuroscience letters

authors： Herness MS

更新日期：1989-11-20 00:00:00

abstract：:Deficit in balance control is a common and often an initial disabling symptom of multiple sclerosis (MS). The aim of the study was to investigate the organization of anticipatory and compensatory postural adjustments in individuals with MS dealing with external perturbations. Ten individuals with MS and ten age-and-ge...

journal_title：Neuroscience letters

authors： Aruin AS,Kanekar N,Lee YJ

更新日期：2015-03-30 00:00:00

abstract：:We recently established adrenal medullary cell line tsAM5D, which was immortalized by use of a temperature-sensitive mutant of the oncogene simian virus 40 large T-antigen. In the present study, when co-treated with glial cell line-derived neurotrophic factor (GDNF) and ciliary neurotrophic factor (CNTF), tsAM5D cells...

journal_title：Neuroscience letters

authors： Murata T,Koide N,Tsuboi M,Kohno S,Hikita K,Kaneda N

更新日期：2008-06-13 00:00:00

abstract：:Restoring corticospinal function after spinal cord injury is a significant challenge as the corticospinal tract elicits no substantive, spontaneous regeneration, and its interruption leaves a permanent deficit. The corticospinal circuit serves multiple motor and sensory functions within the mammalian nervous system as...

journal_title：Neuroscience letters

authors： Serradj N,Agger SF,Hollis ER 2nd

更新日期：2017-06-23 00:00:00

abstract：:Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

journal_title：Neuroscience letters

authors： Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

更新日期：2012-11-14 00:00:00

abstract：:Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attem...

journal_title：Neuroscience letters

authors： Souza RP,De Luca V,Manchia M,Kennedy JL

更新日期：2011-02-11 00:00:00

abstract：:The long-term potentiation (LTP) was studied using rat hippocampal slices in vitro. LTP in mossy fiber-CA3 pyramidal cell synapses was markedly suppressed in slices prepared from rats which had previously received intraventricular injection of pertussis toxin (PTX), compared with the bovine serum albumin-injected cont...

journal_title：Neuroscience letters

authors： Ito I,Okada D,Sugiyama H

更新日期：1988-07-19 00:00:00

abstract：:Neuropeptide VF (NPVF) induces satiety through hypothalamic interactions; however, the central mechanism that mediates these effects is poorly understood. Therefore, this study was conducted to explore some possible opioid receptor associated mechanisms of NPVF-induced satiety using chicks as models. Co-injection of N...

journal_title：Neuroscience letters

authors： Cline MA,Sliwa LN

更新日期：2009-05-22 00:00:00

abstract：:We identified a 45-kDa protein by 2D electrophoresis that was enhanced following pentylenetetrazol (PTZ)-mediated seizures. Mass-spectrography of this protein revealed the beta subunit of Ca2+/calmodulin-dependent protein kinase II (CaMKIIbeta), although no evidence for increase in bulk CaMKIIbeta transcripts was obta...

journal_title：Neuroscience letters

authors： Matsu-ura T,Nakadai T,Oda Y,Nagasu T,Mikoshiba K,Tamura TA

更新日期：2002-04-12 00:00:00

abstract：:Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

journal_title：Neuroscience letters

authors： Peters J,Daum I

更新日期：2009-05-01 00:00:00

abstract：:Electrical stimulation of the primary auditory cortex (AI) of the cat was found to evoke EPSPs, IPSPs or EPSP-IPSP sequences in colliculogeniculate (CG) neurons in the inferior colliculus (IC) which responded antidromically to stimulation of the medial geniculate nucleus. The CG neurons responding to the AI stimulatio...

journal_title：Neuroscience letters

authors： Mitani A,Shimokouchi M,Nomura S

更新日期：1983-12-02 00:00:00

abstract：:Experiments using functional magnetic resonance imaging (fMRI) play a fundamental role in affective neuroscience. When placed in an MR scanner, some volunteers feel safe and relaxed in this situation, while others experience uneasiness and fear. Little is known about the basis and consequences of such inter-individual...

journal_title：Neuroscience letters

authors： Mutschler I,Wieckhorst B,Meyer AH,Schweizer T,Klarhöfer M,Wilhelm FH,Seifritz E,Ball T

更新日期：2014-11-07 00:00:00

abstract：:Although chlorpromazine was shown to greatly inhibit a Ca2+-mediated cell death at favorable concentrations (10(-6)-10(-5) M), it caused a drastic decrease in cell viability at higher concentrations (10(-4)-10(-3) M) in a human neuroblastoma cell line. The toxic effect of chlorpromazine also occurred in Ca2+-free medi...

journal_title：Neuroscience letters

authors： Abe K,Sekizawa T,Kogure K

更新日期：1986-11-21 00:00:00

abstract：:The present study examined effects of high altitude exposure, which leads to development of hypoxia, on epiplexus cells associated with the choroid plexus in adult rats. At 2-5 h following exposure, epiplexus cells expressing inducible nitric oxide synthase (iNOS) were commonly observed. Increased expression of comple...

journal_title：Neuroscience letters

authors： Wang D,Kaur C

更新日期：2000-05-19 00:00:00

abstract：:Bath-applied N-methyl-D,L-aspartate (NMA) was found to elicit locomotor electromyogram (EMG) activity in ankle flexor and extensor muscles in an in vitro lumbar cord-hindlimb preparation of the newborn rat. The frequency and burst duration of the NMA-induced rhythmic EMG activity varied in a dose-dependent manner. The...

journal_title：Neuroscience letters

authors： Kudo N,Yamada T

更新日期：1987-03-20 00:00:00

abstract：:Although minocycline has been generally thought to have neuroprotective properties, the neuroprotective role of minocycline has not been investigated in the animal model of epilepsy. In this study, we investigated whether minocycline is neuroprotective against kainic acid (KA)-induced cell death through the caspase-de...

journal_title：Neuroscience letters

authors： Heo K,Cho YJ,Cho KJ,Kim HW,Kim HJ,Shin HY,Lee BI,Kim GW

更新日期：2006-05-08 00:00:00

abstract：:This study assessed the effect of the kappa opioid receptor agonist U50,488 administered into the rat temporomandibular joint (TMJ) on nociceptive behavioral responses evoked by formalin injected into the same site. Groups consisted of females, stratified into proestrus and diestrus phases of the estrous cycle, and ma...

journal_title：Neuroscience letters

authors： Clemente JT,Parada CA,Veiga MC,Gear RW,Tambeli CH

更新日期：2004-12-06 00:00:00

abstract：:In this study we examined the presence of dopamine D1 receptors in monkey amniotic epithelial cells (MAEC) using RT-PCR and radioligand binding experiments. We found that MAEC express D1 receptor mRNA that is having 99% homology with human dopamine D1 receptors. Saturation binding studies using [3H]SCH-23390 showed a ...

journal_title：Neuroscience letters

authors： Elwan MA,Ishii T,Ono F,Sakuragawa N

更新日期：1999-02-26 00:00:00

abstract：:Flupirtine is a centrally acting nonopioid analgesic with muscle-relaxant properties. Flupirtine has been found to activate inwardly rectifying potassium conductances and hence to indirectly inhibit the activation of NMDA receptors. NMDA receptor activation is crucial for the induction of long-term potentiation (LTP) ...

journal_title：Neuroscience letters

authors： Azad SC,Eder M,Simon W,Hapfelmeier G,Dodt HU,Zieglgänsberger W,Rammes G

更新日期：2004-11-11 00:00:00

abstract：:Circadian rhythms of pineal melatonin release were measured in freely moving pigeons (Columba livia) by in vivo microdialysis. The birds were placed in light-dark cycles with 12 h of light and 12 h of darkness (LD 12:12) or continuous dim light (LLdim) after LD 12:12. Although the level of melatonin was various, daily...

journal_title：Neuroscience letters

authors： Hasegawa M,Ebihara S

更新日期：1992-12-14 00:00:00

abstract：:Freezing is one of the most widely recognized defensive reactions to approaching threats in animals. Here we tested whether the same stimuli can elicit freeze-like responses in healthy humans as well. We used a modified version of the two-frame apparent motion paradigm, in which both size and location of a stimulus wi...

journal_title：Neuroscience letters

authors： Sagliano L,Cappuccio A,Trojano L,Conson M

更新日期：2014-02-21 00:00:00

abstract：:Focal cortical dysplasia (FCD) is an important cause of refractory epilepsy in humans. The origin of its pathognomonic abnormal cell types and the links between abnormal cell morphology and epileptogenicity remain unknown. The developmentally-regulated kinase cdk5 and its neuronal activator p35 are known to be central...

journal_title：Neuroscience letters

authors： Sisodiya SM,Thom M,Lin WR,Bajaj NP,Cross JH,Harding BN

更新日期：2002-08-16 00:00:00

abstract：:beta-Bungarotoxin (BuTx)-binding cells were immunocytochemically examined in the developing rat cerebellum. The tissue was incubated with BuTx and then immunostained with antiserum against its toxoid. On postnatal day 6, only Golgi cells were positive for immunoreaction. Immunoreactive Golgi cells were reduced in numb...

journal_title：Neuroscience letters

authors： Katoh-Semba R,Semba R,Kashiwamata S

更新日期：1987-04-23 00:00:00

abstract：:Amyloid beta (Aβ) is the main component of the amyloid plaques that accumulate in the brains of Alzheimer patients. Here, we reported the protective role of Formononetin (Form) against Aβ25-35-induced neurotoxicity in HT22 cells. We found that Form significantly increased the viability of HT22 cells but decreased the ...

journal_title：Neuroscience letters

authors： Chen L,Ou S,Zhou L,Tang H,Xu J,Guo K

更新日期：2017-02-03 00:00:00

abstract：:We used physiological and anatomical methods to elucidate how the visual field is represented in the part of the dorsal anterior thalamus of the leopard frog that receives direct retinal projections. We recorded extracellularly while presenting visual stimuli, and characterized a physiologically defined region that en...

journal_title：Neuroscience letters

authors： Skorina LK,Recktenwald EW,Dudkin EA,Saidel WM,Gruberg ER

更新日期：2016-05-16 00:00:00

abstract：:The isthmo-optic system is less developed in birds feeding-on-the-wing, than in pecking avians. This was suggested previously. By intraocular horseradish peroxidase applications, we studied the central origin of this retino-petal system in thrush, haw finch, swift and swallow. Our data support the assumption on a corr...

journal_title：Neuroscience letters

authors： Feyerabend B,Malz CR,Meyer DL

更新日期：1994-11-21 00:00:00

abstract：:Changes in cytokine and chemokine expression during Wallerian degeneration have been studied using nerve transection models, which result in denervation of both myelinating and non-myelinating Schwann cells. Cytokine and chemokine response of non-myelinating Remak Schwann cells to loss of their axons is unknown. In th...

journal_title：Neuroscience letters

authors： Cheepudomwit T,Güzelsu E,Zhou C,Griffin JW,Höke A

更新日期：2008-01-17 00:00:00

abstract：:There are numerous polymorphisms within the tau gene but these are in complete linkage disequilibrium and exist as two common extended haplotypes H1 and H2. We have investigated the frequency of these haplotypes in 83 cases of sporadic Alzheimer's disease (AD) using the +34 polymorphism in intron 11 of the tau gene as...

journal_title：Neuroscience letters

authors： Green EK,Thaker U,McDonagh AM,Iwatsubo T,Lambert JC,Chartier-Harlin MC,Harris JM,Pickering-Brown SM,Lendon CL,Mann DM

更新日期：2002-05-17 00:00:00