Abstract:
:It is known that globin genes contain three exons with the middle exon coding for a four-helical supersecondary structure responsible for heme binding. Since this portion of the globin peptide chain can be structurally superimposed onto the cytochrome c and cytochrome b5 chains (Argos and Rossmann 1979), it can be inferred that the cytochrome c gene will contain only one coding sequence while the cytochrome b5 gene will be composed of three exons as found in the globin gene.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Argos P,Rossmann MGdoi
10.1007/BF01731583subject
Has Abstractpub_date
1980-12-01 00:00:00pages
149-50issue
2eissn
0022-2844issn
1432-1432journal_volume
16pub_type
杂志文章abstract::DEAD-box proteins are found in all domains of life and participate in almost all cellular processes that involve RNA. The presence of DEAD and Helicase_C conserved domains distinguish these proteins. DEAD-box proteins exhibit RNA-dependent ATPase activity in vitro, and several also show RNA helicase activity. In this ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-011-9441-8
更新日期:2011-04-01 00:00:00
abstract::We have identified and completely sequenced a novel plasmid isolated from the aphid Rhopalosiphum padi. Evidence which suggests that the plasmid occurs localized within the bacterial endosymbionts is presented. The plasmid contains the four genes that constitute the entire leucine operon. This fact makes it really uni...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00174042
更新日期:1995-07-01 00:00:00
abstract::Autosomal chorion genes s18, s15, and s19 are shown to diverge at extremely rapid rates in closely related taxa of Hawaiian Drosophila. Their nucleotide divergence rates are at least as fast as those of intergenic regions that are known to evolve more extensively between distantly related species. Their amino acid div...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02106055
更新日期:1990-11-01 00:00:00
abstract::While studies of the evolutionary histories of protein families are commonplace, little is known on noncoding RNAs beyond microRNAs and some snoRNAs. Here we investigate in detail the evolutionary history of the nine spliceosomal snRNA families (U1, U2, U4, U5, U6, U11, U12, U4atac, and U6atac) across the completely o...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-008-9149-6
更新日期:2008-12-01 00:00:00
abstract::Fimbrial adhesins allow bacteria to interact with and attach to their environment. The bacteria possibly benefit from these interactions, but all external structures including adhesins also allow bacteria to be identified by other organisms. Thus adhesion molecules might be under multiple forms of selection including ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010148
更新日期:2001-02-01 00:00:00
abstract::In the maximum likelihood (ML) method for estimating a molecular phylogenetic tree, the pattern of nucleotide substitutions for computing likelihood values is assumed to be simpler than that of the actual evolutionary process, simply because the process, considered to be quite devious, is unknown. The problem, however...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02099932
更新日期:1991-01-01 00:00:00
abstract::In studies of molecular evolution, the assumption that protein evolution is reversible has often been made, but rarely tested. Here we use a large set of orthologous murid protein coding sequences to perform a simple test of reversibility, and find no evidence to reject the assumption of reversibility in protein evolu...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010176
更新日期:2001-05-01 00:00:00
abstract::In Trypanoplasma borelli, a representative of the Bodonina within the Kinetoplastida, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity was detected in both the cytosol and glycosomes. This situation is similar to that previously found in Trypanosomatidae, belonging to a different Kinetoplastida suborder. In T...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00164030
更新日期:1995-04-01 00:00:00
abstract::One of the pupal cuticle protein (PCP) genes has been found within an intron of a Drosophila housekeeping gene (the Gart locus) that encodes three enzymes involved in the purine pathway. This intronic gene has been described as a gene within a gene, and the gene is now called a "nested" gene. Because the intronic PCP ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02603074
更新日期:1989-05-01 00:00:00
abstract::Previously we suggested that four proteins including aldolase and triose phosphate isomerase (TPI) evolved with approximately constant rates over long periods covering the whole animal phyla. The constant rates of aldolase and TPI evolution were reexamined based on three different models for estimating evolutionary di...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006208
更新日期:1997-07-01 00:00:00
abstract::Microsatellite DNA sequences have become the dominant source of nuclear genetic markers for most applications. It is important to investigate the basis of variation between alleles and to know if current assumptions about the mechanisms of microsatellite mutation (that is to say, variations involving simple changes in...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006151
更新日期:1997-03-01 00:00:00
abstract::Several studies in Drosophila have shown a paucity of male-biased genes (i.e., genes that express higher in males than in females) on the X chromosome. Dosage compensation (DC) is a regulatory mechanism of gene expression triggered in males that hypertranscribes the X-linked genes to the level of transcription in fema...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-016-9735-y
更新日期:2016-05-01 00:00:00
abstract::Gene duplication creates a second copy of a gene either in tandem to the ancestral locus or dispersed to another chromosomal location. When the ancestral copy of a dispersed duplicate is lost from the genome, it creates the appearance that the gene was "relocated" from the ancestral locus to the derived location. Gene...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-018-9849-5
更新日期:2018-07-01 00:00:00
abstract::The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimp...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02115687
更新日期:1985-01-01 00:00:00
abstract::Nucleotide sequences for the kappa-casein precursor proteins have been determined from the genomic DNAs or hair roots of the Ruminantia. The coding regions, exons 2, 3, and 4, were amplified separately via the three kinds of PCRs and then directly sequenced. The primers were designed from the sequence of bovine kappa-...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00173165
更新日期:1995-12-01 00:00:00
abstract::The in vitro expression of two distinct proteins from overlapping reading frames in a sequence of rainbow trout genomic DNA has been demonstrated. In vitro transcription of DNA sequences, cloned in a plasmid under the control of Salmonella phage 6 polymerase promoter, led to the synthesis of two distinct and functiona...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02099952
更新日期:1986-01-01 00:00:00
abstract::The mammalian defensin molecule is a short, highly cationic peptide cytotoxic to both microbial and mammalian cells which is cleaved from a precursor including a signal peptide and a highly anionic propiece. A phylogenetic analysis of 28 complete sequences from five mammalian species (mouse, rat, guinea pig, rabbit, a...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006191
更新日期:1997-06-01 00:00:00
abstract::A common polymorphism of the early embryonic histone-gene repeat of Strongylocentrotus purpuratus is a 195-bp insertion within the H4-H2B spacer. The sequence, found as an insert in histone-gene repeats of 6 of 22 individuals screened, is also found at approximately 50 sites elsewhere in the genome of every individual...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02134133
更新日期:1987-01-01 00:00:00
abstract::Molecular domestication of a transposable element is defined as its functional recruitment by the host genome. To date, two independent events of molecular domestication of the P transposable element have been described: in the Drosophila obscura species group and in the Drosophila montium species subgroup. These P ne...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-004-0324-0
更新日期:2005-10-01 00:00:00
abstract::Twenty-seven protein sequence elements, six to nine amino acids long, were extracted from 15 phylogenetically diverse complete prokaryotic proteomes. The elements are present in all of these proteomes, with at least one copy each (omnipresent elements), and have presumably been conserved since the last universal commo...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-007-9032-x
更新日期:2007-12-01 00:00:00
abstract::When an aqueous solution (pH 7.0) of 3H deoxythymidine 5'-triphosphate, deoxythymidine 5'-phosphate, 4-amino-5-imidazolecarboxamide, cyanamide and ammonium chloride was dried and heated at 60 degrees C for 18 h, oligomers were obtained in a yield of approximately 80%. After the chemical degradation of any pyrophosphat...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01764595
更新日期:1977-12-29 00:00:00
abstract::Multiple genes of the hoatzin encoding stomach lysozyme c and closely related members of this calcium-binding lysozyme c group were cloned from a genomic DNA library and sequenced. There are a minimum of five genes represented among these sequences that encode two distinct groups of protein sequences. One group of thr...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02338801
更新日期:1996-06-01 00:00:00
abstract::One of the key problems in the study of ancient DNA is that of authenticating sequences obtained from PCR amplifications of highly degraded samples. Contamination of ancient samples and postmortem damage to endogenous DNA templates are the major obstacles facing researchers in this task. In particular, the authenticat...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-006-0259-8
更新日期:2007-07-01 00:00:00
abstract::Variation in structure among primate hemoglobins is associated with variation in function. This supports the hypothesis that most substitutions observed among homologous proteins in different species have been fixed by natural selection because they contribute to the fitness of the genotype. It does not support the co...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01653958
更新日期:1972-12-01 00:00:00
abstract::Single-fly polymerase chain reaction amplification and direct DNA sequencing revealed high levels of length polymorphism in the threonine-glycine encoding repeat region of the period (per) gene in natural populations of Drosophila melanogaster. DNA comparison of two alleles of identical lengths gave a high number of s...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02342746
更新日期:1991-03-01 00:00:00
abstract::RNA has a myriad of biological roles in contemporary life. We use the RNA paradigm for genotype-phenotype mappings to study the evolution of multiple coding in dependence to mutation rates. We study three different one-to-many genotype-phenotype mappings which have the potential to encode the information for multiple ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-014-9648-6
更新日期:2014-12-01 00:00:00
abstract::The organization of histone gene clusters of the duck Cairina moschata was studied in the DNA inserts of two recombinant phage that overlap and feature identical histone gene arrangements but differ in sequence details and in the extent of repetition of an AT-rich motif in one of the nontranscribed spacer regions. The...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02102477
更新日期:1989-03-01 00:00:00
abstract::Analysis of mitochondrial DNAs (mtDNAs) from parthenogenetic lizards of the Heteronotia binoei complex with restriction enzymes revealed an approximately 5-kb addition present in all 77 individuals. Cleavage site mapping suggested the presence of a direct tandem duplication spanning the 16S and 12S rRNA genes, the con...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02103135
更新日期:1991-11-01 00:00:00
abstract::Evolutionary divergence times can be inferred from molecular distances if a molecular clock can be assumed and if the substitution rate can be estimated. We present new evidence from relative rate tests that the rate of substitution at fourfold degenerate sites of nuclear genome-coding DNA is uniform in primate and ro...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00000066
更新日期:1997-01-01 00:00:00
abstract::Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-010-9394-3
更新日期:2010-12-01 00:00:00