The relationship between coding sequences and function in some heme binding proteins.

Abstract:

:It is known that globin genes contain three exons with the middle exon coding for a four-helical supersecondary structure responsible for heme binding. Since this portion of the globin peptide chain can be structurally superimposed onto the cytochrome c and cytochrome b5 chains (Argos and Rossmann 1979), it can be inferred that the cytochrome c gene will contain only one coding sequence while the cytochrome b5 gene will be composed of three exons as found in the globin gene.

journal_name

J Mol Evol

authors

Argos P,Rossmann MG

doi

10.1007/BF01731583

subject

Has Abstract

pub_date

1980-12-01 00:00:00

pages

149-50

issue

2

eissn

0022-2844

issn

1432-1432

journal_volume

16

pub_type

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