Combinations of ancestral modules in proteins.

abstract：:Evaporation of a solution of thymidine plus either the exo or the endo diastereomer of uridine cyclic 2',3'-O, O-phosphorothioate (U greater than p(S) in 1,2-diaminoethane hydrochloride buffer gave the 2',5' and 3',5' isomers of (P-thio) uridylylthymidine (Up(S)dT) in a ratio of 1:2 with a combined yield of about 20%....

journal_title：Journal of molecular evolution

authors： Usher DA,Yee D

更新日期：1979-11-01 00:00:00

abstract：:We describe the structure of a gene expressed in the salivary gland cells of the dipteran Chironomus tentans and show that it encodes 1 of the approximately 15 secretory proteins exported by the gland cells. This sp115,140 gene consists of approximately 65 copies of a 42-bp sequence in a central uninterrupted core blo...

journal_title：Journal of molecular evolution

authors： Galli J,Lendahl U,Paulsson G,Ericsson C,Bergman T,Carlquist M,Wieslander L

更新日期：1990-07-01 00:00:00

abstract：:The monotremes, the duck-billed platypus and the echidnas, are characterized by a number of unique morphological characteristics, which have led to the common belief that they represent the living survivors of an ancestral stock of mammals. Analysis of new data from the complete mitochondrial (mt) genomes of a second ...

journal_title：Journal of molecular evolution

authors： Janke A,Magnell O,Wieczorek G,Westerman M,Arnason U

更新日期：2002-01-01 00:00:00

abstract：:Nucleotide sequences for the kappa-casein precursor proteins have been determined from the genomic DNAs or hair roots of the Ruminantia. The coding regions, exons 2, 3, and 4, were amplified separately via the three kinds of PCRs and then directly sequenced. The primers were designed from the sequence of bovine kappa-...

journal_title：Journal of molecular evolution

authors： Chikuni K,Mori Y,Tabata T,Saito M,Monma M,Kosugiyama M

更新日期：1995-12-01 00:00:00

abstract：:HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become avai...

journal_title：Journal of molecular evolution

authors： Griess EA,Rensing SA,Grasser KD,Maier UG,Feix G

更新日期：1993-08-01 00:00:00

abstract：:Characterization of sequences homologous to the Drosophila melanogaster gypsy transposable element was carried out in Drosophila subobscura (gypsyDS). They were found to be widely distributed among natural populations of this species. From Southern blot and in situ analyses, these sequences appear to be mobile in this...

journal_title：Journal of molecular evolution

authors： Alberola TM,de Frutos R

更新日期：1993-02-01 00:00:00

abstract：:A+T content, phylogenetic relationships, codon usage, evolutionary rates, and ratio of synonymous versus non-synonymous substitutions have been studied in partial sequences of the atpD and aroQ/pheA genes of primary ( Buchnera) and secondary symbionts of aphids and a set of selected non-symbiotic bacteria, belonging t...

journal_title：Journal of molecular evolution

authors： Moya A,Latorre A,Sabater-Muñoz B,Silva FJ

更新日期：2002-08-01 00:00:00

abstract：:Heat induces a number of premutational lesions (for example, the deamination of cytosine to uracil) in DNA and RNA. These kinds of errors occur in resting as well as replicating polynucleotides. However, an increase in temperature also raises the probability of copying error occurring in nucleic acids because of incre...

journal_title：Journal of molecular evolution

authors： Reanney DC,Pressing J

更新日期：1984-01-01 00:00:00

abstract：:The gas chromatograph mass spectrometer instrument of the Viking mission has demonstrated the absence of organic compounds in the immediate surface layer of the two landing sites. The demonstration of the successful operation of the instrument (comparison of ground-based test data with those obtained during interplane...

journal_title：Journal of molecular evolution

authors： Biemann K

更新日期：1979-12-01 00:00:00

abstract：:Single-fly polymerase chain reaction amplification and direct DNA sequencing revealed high levels of length polymorphism in the threonine-glycine encoding repeat region of the period (per) gene in natural populations of Drosophila melanogaster. DNA comparison of two alleles of identical lengths gave a high number of s...

journal_title：Journal of molecular evolution

authors： Costa R,Peixoto AA,Thackeray JR,Dalgleish R,Kyriacou CP

更新日期：1991-03-01 00:00:00

abstract：:The diversity of functional genes and the related processes are important issues for conservation biology. This is especially relevant for populations that have suffered from demographic reduction as a consequence of the processes of postglacial colonization. In this perspective, the aims of the present study are (1) ...

journal_title：Journal of molecular evolution

authors： Girard P,Angers B

更新日期：2011-08-01 00:00:00

abstract：:We analyzed precursor messenger RNAs (pre-mRNAs) of 12 eukaryotic species. In each species, three groups of highly expressed genes, ribosomal proteins, heat shock proteins, and amino-acyl tRNA synthetases, were compared with a control group (randomly selected genes). The purine-pyrimidine (R-Y) composition of pre-mRNA...

journal_title：Journal of molecular evolution

authors： Paz A,Mester D,Nevo E,Korol A

更新日期：2007-02-01 00:00:00

abstract：:We obtained and studied HIV-1 sequences with a known sampling year from three outbreaks of the HIV-1 epidemic: 141 env V3 (270 nt) sampled between 1984 and 1992 and 117 pol prot/RT (804 nt) sequences sampled between 1986 and 1999 from Dutch homosexual men and injecting drug users (IDUs), as well as 77 env V3 sequences...

journal_title：Journal of molecular evolution

authors： Lukashov VV,Goudsmit J

更新日期：2002-05-01 00:00:00

abstract：:Scorpion venom toxins were systematically classified according to amino acid composition, insertion/deletion events and sequence. The significance of each comparison method and its outcome is discussed in relation to known immunological and structural properties. A general classification of the toxins is proposed that...

journal_title：Journal of molecular evolution

authors： Dufton MJ,Rochat H

更新日期：1984-01-01 00:00:00

abstract：:By considering three DNA sequences simultaneously there is sufficient information to recover a full Markov model with three transition matrices from the root to each of the sequences. It is necessary to have relatively long sequences because, for nucleotides, the full model requires 39 parameters that are estimated fr...

journal_title：Journal of molecular evolution

authors： Ota R,Penny D

更新日期：2003-01-01 00:00:00

abstract：:In this paper we present a new method for detecting block duplications in a genome. It is more stringent than previous ones in that it requires a more rigorous definition of paralogous genes and that it requires the paralogous proteins on the two blocks to be contiguous. In addition, it provides three criterion choice...

journal_title：Journal of molecular evolution

authors： Cavalcanti AR,Ferreira R,Gu Z,Li WH

更新日期：2003-01-01 00:00:00

abstract：:Recombination has been suggested to be an important factor for the genetic variation of bacterial genes, but few studies have dealt with intragenic recombination between the same or closely related species of cyanobacteria. Here we provide strong evidence for recombination in the microcystin synthetase (mcy) gene clus...

journal_title：Journal of molecular evolution

authors： Tanabe Y,Kaya K,Watanabe MM

更新日期：2004-06-01 00:00:00

abstract：:The NF-κB family of transcription factors is activated in response to many environmental and biological stresses, and plays a key role in innate immunity across a broad evolutionary expanse of animals. A simple NF-κB pathway is present in the sea anemone Nematostella vectensis, an important model organism in the phylu...

journal_title：Journal of molecular evolution

authors： Wolenski FS,Chandani S,Stefanik DJ,Jiang N,Chu E,Finnerty JR,Gilmore TD

更新日期：2011-12-01 00:00:00

abstract：:The 5S ribosomal RNA sequences have been determined for the rhodoplast of the red alga Porphyra umbilicalis and the chloroplast of the conifer Juniperus media. The 5S RNA sequence of the Vicia faba chloroplast is corrected with respect to a previous report. A survey of the known sequences and secondary structures of 5...

journal_title：Journal of molecular evolution

authors： Van den Eynde H,De Baere R,De Roeck E,Van de Peer Y,Vandenberghe A,Willekens P,De Wachter R

更新日期：1988-01-01 00:00:00

abstract：:Autosomal chorion genes s18, s15, and s19 are shown to diverge at extremely rapid rates in closely related taxa of Hawaiian Drosophila. Their nucleotide divergence rates are at least as fast as those of intergenic regions that are known to evolve more extensively between distantly related species. Their amino acid div...

journal_title：Journal of molecular evolution

authors： Martínez-Cruzado JC

更新日期：1990-11-01 00:00:00

abstract：:The glycosylation characteristics of the digestive enzyme ribonuclease are summarized. The evolutionary role of this posttranslational modification is discussed and evidence is presented that selection has much influence on the presence or absence of carbohydrate in glycoproteins and on the positions of the carbohydra...

journal_title：Journal of molecular evolution

authors： Beintema JJ

更新日期：1986-01-01 00:00:00

abstract：:The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimp...

journal_title：Journal of molecular evolution

authors： Sawada I,Willard C,Shen CK,Chapman B,Wilson AC,Schmid CW

更新日期：1985-01-01 00:00:00

abstract：:Natural populations of the Midas cichlid species in several different crater lakes in Nicaragua exhibit a conspicuous color polymorphism. Most individuals are dark and the remaining have a gold coloration. The color morphs mate assortatively and sympatric population differentiation has been shown based on neutral mole...

journal_title：Journal of molecular evolution

authors： Henning F,Renz AJ,Fukamachi S,Meyer A

更新日期：2010-05-01 00:00:00

abstract：:In Trypanoplasma borelli, a representative of the Bodonina within the Kinetoplastida, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity was detected in both the cytosol and glycosomes. This situation is similar to that previously found in Trypanosomatidae, belonging to a different Kinetoplastida suborder. In T...

journal_title：Journal of molecular evolution

authors： Wiemer EA,Hannaert V,van den IJssel PR,Van Roy J,Opperdoes FR,Michels PA

更新日期：1995-04-01 00:00:00

abstract：:Evidence from a number of studies indicates that protein folding is dictated not only by factors stabilizing the native state, but also by potentially independent factors that create folding pathways. How natural selection might cope simultaneously with two independent factors was addressed in this study within the fr...

journal_title：Journal of molecular evolution

authors： Lee SY,Parker W

更新日期：2011-10-01 00:00:00

abstract：:One of the pupal cuticle protein (PCP) genes has been found within an intron of a Drosophila housekeeping gene (the Gart locus) that encodes three enzymes involved in the purine pathway. This intronic gene has been described as a gene within a gene, and the gene is now called a "nested" gene. Because the intronic PCP ...

journal_title：Journal of molecular evolution

authors： Moriyama EN,Gojobori T

更新日期：1989-05-01 00:00:00

abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...

journal_title：Journal of molecular evolution

authors： Wallis M

更新日期：2000-05-01 00:00:00

abstract：:The periodic protein collagen is of special interest for the study of the relationship which exists between the structure of a protein and that of its mRNA, because oligopeptides containing glycine, proline (hydroxyproline) and alanine occur with great frequency in it. Collagen is particularly rich in these amino acid...

journal_title：Journal of molecular evolution

authors： Bachra BN

更新日期：1976-08-03 00:00:00

abstract：:Tests for positive selection have mostly been developed to look for diversifying selection where change away from the current amino acid is often favorable. However, in many cases we are interested in directional selection where there is a shift toward specific amino acids, resulting in increased fitness in the specie...

journal_title：Journal of molecular evolution

authors： Thiltgen G,Dos Reis M,Goldstein RA

更新日期：2017-01-01 00:00:00

abstract：:We recently sequenced the genome of the first subterrestrial metazoan, the nematode Halicephalobus mephisto. A central finding was a dramatic expansion of genes encoding avrRpt2 induced gene (AIG1), and 70 kDa heat shock (Hsp70) domains. While the role of Hsp70 in thermotolerance is well established, the contribution ...

journal_title：Journal of molecular evolution

authors： Guerin MN,Weinstein DJ,Bracht JR

更新日期：2019-12-01 00:00:00