The implications and limitations of the findings of the Viking organic analysis experiment.

abstract：:Amino acid substitution models represent substitution rates among amino acids during the evolution. The models play an important role in analyzing protein sequences, especially inferring phylogenies. The rapid evolution of flaviviruses is expanding the threat in public health. A number of models have been estimated fo...

journal_title：Journal of molecular evolution

authors： Le TK,Vinh LS

更新日期：2020-07-01 00:00:00

abstract：:Low oxygen and fluctuant ambient temperature pose serious challenges to mammalian survival. Physiological adaptations in mammals to hypoxia and low temperatures have been intensively investigated, yet their underlying molecular mechanisms need further exploration. Independent invasions of high-altitude plateaus, subte...

journal_title：Journal of molecular evolution

authors： Zhu K,Ge D,Wen Z,Xia L,Yang Q

更新日期：2018-12-01 00:00:00

abstract：:The neutral theory of molecular evolution states that most mutations are deleterious or neutral. It results that the evolutionary rate of a given position in an alignment is a function of the level of constraint acting on this position. Inferring evolutionary rates from a set of aligned sequences is hence a powerful m...

journal_title：Journal of molecular evolution

authors： Dutheil J

更新日期：2008-09-01 00:00:00

abstract：:Algae are a heterogeneous group of photosynthetic eukaryotes traditionally separated into three major subdivisions: rhodophytes, chlorophytes, and chromophytes. The evolutionary origin of rhodophytes or red algae and their links to other photosynthetic and nonphotosynthetic eukaryotes have been a matter of much contro...

journal_title：Journal of molecular evolution

authors： Liaud MF,Valentin C,Martin W,Bouget FY,Kloareg B,Cerff R

更新日期：1994-04-01 00:00:00

abstract：:The genome of Glycine max (L.) Merr. cv. "Dare" contains a chlorophyll a/b binding (Cab) protein gene family consisting of 10 genes. The primary structures of two linked Cab genes (Cab 4 and Cab 5) were determined. A comparison of the nucleic acid and predicted amino acid sequences of Cab 4 and Cab 5 revealed a high d...

journal_title：Journal of molecular evolution

authors： Demmin DS,Stockinger EJ,Chang YC,Walling LL

更新日期：1989-09-01 00:00:00

abstract：:Phylogenetic relationships of 25 mammalian species representing 17 of the 18 eutherian orders were examined using DNA sequences from a 1.2-kb region of the 5' end of exon 1 of the single-copy nuclear gene known as interphotoreceptor retinoid binding protein (IRBP). A wide variety of methods of analysis of the DNA sequ...

journal_title：Journal of molecular evolution

authors： Stanhope MJ,Smith MR,Waddell VG,Porter CA,Shivji MS,Goodman M

更新日期：1996-08-01 00:00:00

abstract：:In the previous three reports in this series we demonstrated that the EF-hand family of proteins evolved by a complex pattern of gene duplication, transposition, and splicing. The dendrograms based on exon sequences are nearly identical to those based on protein sequences for troponin C, the essential light chain myos...

journal_title：Journal of molecular evolution

authors： Kretsinger RH,Nakayama S

更新日期：1993-05-01 00:00:00

abstract：:It has recently been argued that living metazoans diverged over 800 million years ago, based on evidence from 22 nuclear genes for such a deep divergence between vertebrates and arthropods (Gu 1998). Two "internal" calibration points were used. However, only one fossil divergence date (the mammal-bird split) was direc...

journal_title：Journal of molecular evolution

authors： Lee MS

更新日期：1999-09-01 00:00:00

abstract：:One crucial event during evolution to multicellularity was the development of either direct cell-cell contact or indirect interaction via extracellular matrix (ECM) molecules. The identification of those polypeptides provides conclusive data on the phylogenetic relationship of metazoan phyla and helps us to understand...

journal_title：Journal of molecular evolution

authors： Schütze J,Skorokhod A,Müller IM,Müller WE

更新日期：2001-10-01 00:00:00

abstract：:We present sequences of five novel RNase A superfamily ribonuclease genes of the bullfrog, Rana catesbeiana. All five genes encode ribonucleases that are similar to Onconase, a cytotoxic ribonuclease isolated from oocytes of R. pipiens. With amino acid sequence data from 14 ribonucleases from three Rana species (R. ca...

journal_title：Journal of molecular evolution

authors： Rosenberg HF,Zhang J,Liao YD,Dyer KD

更新日期：2001-07-01 00:00:00

abstract：:Recent experience with molecular phylogeny has shown that all molecular markers have strengths and weaknesses. Nonetheless, despite several notable discrepancies with phylogenies obtained from protein data, the merits of the small subunit ribosomal RNA (SSU rRNA) as a molecular phylogenetic marker remain indisputable....

journal_title：Journal of molecular evolution

authors： Van de Peer Y,Baldauf SL,Doolittle WF,Meyer A

更新日期：2000-12-01 00:00:00

abstract：:Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...

journal_title：Journal of molecular evolution

authors： Xiang H,Pan G,Vossbrinck CR,Zhang R,Xu J,Li T,Zhou Z,Lu C,Xiang Z

更新日期：2010-12-01 00:00:00

abstract：:Complete chloroplast 23S rRNA and psbA genes from five peridinin-containing dinoflagellates (Heterocapsa pygmaea, Heterocapsa niei, Heterocapsa rotun-data, Amphidinium carterae, and Protoceratium reticulatum) were amplified by PCR and sequenced; partial sequences were obtained from Thoracosphaera heimii and Scrippsiel...

journal_title：Journal of molecular evolution

authors： Zhang Z,Green BR,Cavalier-Smith T

更新日期：2000-07-01 00:00:00

abstract：:The evolutionary speed and the consequent immune escape of H3N2 influenza A virus make it an interesting evolutionary system. Charged amino acid residues are often significant contributors to the free energy of binding for protein-protein interactions, including antibody-antigen binding and ligand-receptor binding. We...

journal_title：Journal of molecular evolution

authors： Pan K,Long J,Sun H,Tobin GJ,Nara PL,Deem MW

更新日期：2011-01-01 00:00:00

abstract：:Single likelihood ancestor counting (SLAC), fixed effects likelihood (FEL), and several random effects likelihood (REL) methods were utilized to identify positively and negatively selected sites in sexually induced gene 1 (Sig1) of four different Thalassiosira species. The SLAC analysis did not find any sites affected...

journal_title：Journal of molecular evolution

authors： Sorhannus U,Kosakovsky Pond SL

更新日期：2006-08-01 00:00:00

abstract：:Bacterial family C DNA polymerases (DNA pol IIIs), the major chromosomal replicative enzymes, have been provisionally classified based on primary sequences and domain structures into three classes: class I (Escherichia coli DNA pol C-type), class II (Bacillus subtilis DNA pol C-type), and class III (cyanobacterial DNA...

journal_title：Journal of molecular evolution

authors： Huang YP,Ito J

更新日期：1999-06-01 00:00:00

abstract：:Short interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplification from one or a few evolving master genes or by (ii) the generation of new master genes that coexist with their progenitors. Individual, highly conserved, elements of the B1 SINE family were identified from t...

journal_title：Journal of molecular evolution

authors： Kass DH,Raynor ME,Williams TM

更新日期：2000-09-01 00:00:00

abstract：:Collagen is an important structural protein and the most abundant protein in mammals. In several research fields, structural analysis of collagens is performed. Fibrillar collagens almost entirely consist of continuous repeats of GXY, where G is glycine, X is often proline or alanine and Y is often hydroxyproline or a...

journal_title：Journal of molecular evolution

authors： Kleinnijenhuis AJ,van Holthoon FL

更新日期：2018-06-01 00:00:00

abstract：:The observed and expected frequencies of occurrence of microsatellites in the yeast Saccharomyces cerevisiae were investigated. In all cases, the observed frequencies exceeded the expected ones. In contrast to predictions by Messier et al. (1996), there is no critical number of repeats beyond which the observed freque...

journal_title：Journal of molecular evolution

authors： Pupko T,Graur D

更新日期：1999-03-01 00:00:00

abstract：:Evolutionary divergence times can be inferred from molecular distances if a molecular clock can be assumed and if the substitution rate can be estimated. We present new evidence from relative rate tests that the rate of substitution at fourfold degenerate sites of nuclear genome-coding DNA is uniform in primate and ro...

journal_title：Journal of molecular evolution

authors： Easteal S,Herbert G

更新日期：1997-01-01 00:00:00

abstract：:The weight-averaged observed/expected dinucleotide frequencies for the sum total of the coding regions of five Toxoplasma genes were compared with the same parameters previously determined for the coding regions of 21 Plasmodium genes. In addition, codon usage in the five Toxoplasma genes was compared with that in the...

journal_title：Journal of molecular evolution

authors： Johnson AM

更新日期：1990-04-01 00:00:00

abstract：:Natural populations of the Midas cichlid species in several different crater lakes in Nicaragua exhibit a conspicuous color polymorphism. Most individuals are dark and the remaining have a gold coloration. The color morphs mate assortatively and sympatric population differentiation has been shown based on neutral mole...

journal_title：Journal of molecular evolution

authors： Henning F,Renz AJ,Fukamachi S,Meyer A

更新日期：2010-05-01 00:00:00

abstract：:Two competing effects at two vastly different scales may explain collagen's current translation length. The necessity to have long molecules for maintaining mechanical integrity at the organism and supraorganism scales may be limited by the need to have small molecules capable of robust self-assembly at the nanoscale....

journal_title：Journal of molecular evolution

authors： Layton BE,D'Souza AJ,Dampier W,Zeiger A,Sabur A,Jean-Charles J

更新日期：2008-06-01 00:00:00

abstract：:Multiple phospholipase A2 (PLA2) isoenzymes found in a single snake venom induce a variety of pharmacological effects. These multiple forms are formed by gene duplication and accelerated evolution of exons. We examined the amino acid sequences of 127 snake venom PLA2 enzymes and their homologues to study in which loca...

journal_title：Journal of molecular evolution

authors： Kini RM,Chan YM

更新日期：1999-02-01 00:00:00

abstract：:The bacterial endosymbionts (Buchnera) from the aphids Rhopalosiphum padi, R. maidis, Schizaphis graminum, and Acyrthosiphon pisum contain the genes for anthranilate synthase (trpEG) on plasmids made up of one or more 3.6-kb units. Anthranilate synthase is the first as well as the rate-limiting enzyme in the tryptopha...

journal_title：Journal of molecular evolution

authors： Rouhbakhsh D,Lai CY,von Dohlen CD,Clark MA,Baumann L,Baumann P,Moran NA,Voegtlin DJ

更新日期：1996-04-01 00:00:00

abstract：:In the present study we focus on the nucleotide and the inferred amino acid variation occurring in humans and other primate species for mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase, a gene recently supposed to contribute to cognitive performance in humans. We determined 2527 bp of coding, introni...

journal_title：Journal of molecular evolution

authors： Blasi P,Palmerio F,Aiello A,Rocchi M,Malaspina P,Novelletto A

更新日期：2006-07-01 00:00:00

abstract：:One of the key problems in the study of ancient DNA is that of authenticating sequences obtained from PCR amplifications of highly degraded samples. Contamination of ancient samples and postmortem damage to endogenous DNA templates are the major obstacles facing researchers in this task. In particular, the authenticat...

journal_title：Journal of molecular evolution

authors： Helgason A,Pálsson S,Lalueza-Fox C,Ghosh S,Sigurdardóttir S,Baker A,Hrafnkelsson B,Arnadóttir L,Thorsteinsdóttir U,Stefánsson K

更新日期：2007-07-01 00:00:00

abstract：:In this study, a new strategy for the selection of aptamers against small-molecule target was established using gold nanoparticles (AuNPs) as the separation matrix and Zinc(II)-Protoporphyrin IX (ZnPPIX) as the target molecule without the immobilization step due to the absorption of ssDNA on AuNPs. The progress of the...

journal_title：Journal of molecular evolution

authors： Li W,Luo Y,Gao T,Yang L,Wang J,Pei R

更新日期：2019-09-01 00:00:00

abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...

journal_title：Journal of molecular evolution

authors： Wallis M

更新日期：2000-05-01 00:00:00

abstract：:The diversity of functional genes and the related processes are important issues for conservation biology. This is especially relevant for populations that have suffered from demographic reduction as a consequence of the processes of postglacial colonization. In this perspective, the aims of the present study are (1) ...

journal_title：Journal of molecular evolution

authors： Girard P,Angers B

更新日期：2011-08-01 00:00:00