Phylogenetic relationships of HMG box DNA-binding domains.

abstract：:We outline a method for estimating quantitatively the influence of point mutations and selection on the frequencies of codons and amino acids. We show how the mutation rate, i.e., the rate of amino acid replacement due to point mutation, can be affected by the codon usage as well as by the rates of the involved base e...

journal_title：Journal of molecular evolution

authors： Frömmel C,Holzhütter HG

更新日期：1984-01-01 00:00:00

abstract：:A general correlation between neural expression and negative charge in isozymes suggests charge represents an adaptation to the neural environment. Interestingly, a notable exception exists in teleost fish. Two cytosolic malate dehydrogenase (MDH) isozymes have different spatial expression patterns in certain fishes: ...

journal_title：Journal of molecular evolution

authors： Merrit TJ,Quattro M

更新日期：2003-03-01 00:00:00

abstract：:There has been considerable discussion in recent years on the evolution of the tandemly repeated multigene families, since some organisms show a concerted model whereas others show a birth-and-death model. This controversial subject extends to several species of fish. In this study, three species of the Sparidae famil...

journal_title：Journal of molecular evolution

authors： Merlo MA,Cross I,Manchado M,Cárdenas S,Rebordinos L

更新日期：2013-03-01 00:00:00

abstract：:Bacterial lipoproteins, characterized by the N-terminal N-acyl S-diacylglyceryl Cysteine, are key membrane proteins in bacterial homeostasis. It is generally thought that during the modification lipoprotein precursors are translocated via the Sec-machinery in an unfolded state. The recent discovery of twin-arginine tr...

journal_title：Journal of molecular evolution

authors： Shruthi H,Babu MM,Sankaran K

更新日期：2010-04-01 00:00:00

abstract：:Seven new Italian and two new British HTLV-II isolates were obtained from injecting drug users and the entire long terminal repeat (LTR) region was sequenced. Restriction analysis showed that all the Italian isolates are of the IIb subtype, whereas the British isolates are of the IIa subtype. To understand whether the...

journal_title：Journal of molecular evolution

authors： Salemi M,Vandamme AM,Gradozzi C,Van Laethem K,Cattaneo E,Taylor G,Casoli C,Goubau P,Desmyter J,Bertazzoni U

更新日期：1998-05-01 00:00:00

abstract：:To understand the process and mechanism of protein evolution, it is important to know what types of amino acid substitutions are more likely to be under selection and what types are mostly neutral. An amino acid substitution can be classified as either conservative or radical, depending on whether it involves a change...

journal_title：Journal of molecular evolution

authors： Zhang J

更新日期：2000-01-01 00:00:00

abstract：:The sequence of the mitochondrial DNA (mtDNA) molecule of the European hedgehog (Erinaceus europaeus) was determined. The length of the sequence presented is 17,442 nucleotides (nt). The molecule is thus the largest eutherian mtDNA molecule so far reported. The organization of the molecule conforms with that of other ...

journal_title：Journal of molecular evolution

authors： Krettek A,Gullberg A,Arnason U

更新日期：1995-12-01 00:00:00

abstract：:Catalyzed by a family of enzymes called glycosyltransferases, glycosylation reactions are essential for the bioactivities of secondary metabolites such as antibiotics. Due to the special characters of antibiotic glycosyltransferases (AGts), antibiotics can function by attaching some unusual deoxy-sugars to their aglyc...

journal_title：Journal of molecular evolution

authors： Liang D,Qiao J

更新日期：2007-03-01 00:00:00

abstract：:A few years ago we presented a stationary Markov model of gene evolution according to which only homologous genes from not too divergent species obeying the condition of being stationary may behave as reliable molecular clocks. A compartmentalized model of the nuclear genome in which the genes are distributed in compa...

journal_title：Journal of molecular evolution

authors： Saccone C,Pesole G,Preparata G

更新日期：1989-11-01 00:00:00

abstract：:By a chromosome walking strategy the DNA region from Methanococcus vannielii flanking the genes for protein synthesis elongation factor (EF) 1 alpha and EF-2 was cloned and sequenced. A gene organization of 5' - beta' - open reading frame (ORF) 1 - ORF2 - S12 - S7 - EF-2 - EF-1 alpha - S10 - ORF3 - ORF4 - 3' was found...

journal_title：Journal of molecular evolution

authors： Lechner K,Heller G,Böck A

更新日期：1989-07-01 00:00:00

abstract：:The evolutionary relationships among arthropod hemocyanins and insect hexamerins were investigated. A multiple sequence alignment of 12 hemocyanin and 31 hexamerin subunits was constructed and used for studying sequence conservation and protein phylogeny. Although hexamerins and hemocyanins belong to a highly divergen...

journal_title：Journal of molecular evolution

authors： Burmester T,Massey HC Jr,Zakharkin SO,Benes H

更新日期：1998-07-01 00:00:00

abstract：:The RpoS sigma factor in proteobacteria regulates genes in stationary phase and in response to stress. Although of conserved function, the RpoS regulon may have different gene composition across species due to high genomic diversity and to known environmental conditions that select for RpoS mutants. In this study, the...

journal_title：Journal of molecular evolution

authors： Chiang SM,Schellhorn HE

更新日期：2010-06-01 00:00:00

abstract：:In this work detailed statistics on ancestral gene duplication and gene conservation in completely sequenced cellular genomes are presented. Analysis of open reading frame (ORF) products having simultaneous matches in several distinct organisms showed a significant correlation between duplication and conservation. Sys...

journal_title：Journal of molecular evolution

authors： Tekaia F,Dujon B

更新日期：1999-11-01 00:00:00

abstract：:We have sequenced the nuclear and mitochondrial small subunit rRNA genes (rns) and the mitochondrial genes coding for subunits 1 and 3 of the cytochrome oxidase (cox1 and cox3, respectively) of the chytridiomycete Allomyces macrogynus. Phylogenetic trees inferred from the derived COX1 and COX3 proteins and the nuclear...

journal_title：Journal of molecular evolution

authors： Paquin B,Forget L,Roewer I,Lang BF

更新日期：1995-11-01 00:00:00

abstract：:We have determined the genomic structure of an integrin beta-subunit gene from the coral, Acropora millepora. The coding region of the gene contains 26 introns, spaced relatively uniformly, and this is significantly more than have been found in any integrin beta-subunit genes from higher animals. Twenty-five of the 26...

journal_title：Journal of molecular evolution

authors： Schmitt DM,Brower DL

更新日期：2001-12-01 00:00:00

abstract：:Sequences were obtained from five species of rodents that are orthologous to an H2a histone pseudogene from Mus musculus. The pseudogene is part of the cluster of replication-dependent histone genes found on Mus musculus chromosome 13. Comparative analysis of these five sequences together with the previously published...

journal_title：Journal of molecular evolution

authors： DeBry RW

更新日期：1998-03-01 00:00:00

abstract：:Complement control proteins (CCPs) contain repeated protein domains, short consensus repeats (SCRs), which must be relevant to diverse functions such as complement activation, coagulation, viral binding, fetal implantation, and self-nonself recognition. Although SCRs share some discontinuous and imperfect motifs, ther...

journal_title：Journal of molecular evolution

authors： McLure CA,Dawkins RL,Williamson JF,Davies RA,Berry J,Natalie LJ,Laird R,Gaudieri S

更新日期：2004-08-01 00:00:00

abstract：:Scorpion venom toxins were systematically classified according to amino acid composition, insertion/deletion events and sequence. The significance of each comparison method and its outcome is discussed in relation to known immunological and structural properties. A general classification of the toxins is proposed that...

journal_title：Journal of molecular evolution

authors： Dufton MJ,Rochat H

更新日期：1984-01-01 00:00:00

abstract：:Several distinct families of endogenous retroviruses exist in the genomes of primates. Most of them are remnants of ancient germ-line infections. The human endogenous retrovirus family HERV-K represents the unique known case of endogenous retrovirus that amplified in the human genome after the divergence of human and ...

journal_title：Journal of molecular evolution

authors： Costas J

更新日期：2001-09-01 00:00:00

abstract：:We have analyzed the gene that encodes receptor tyrosine kinase (RTK) from the marine sponge Geodia cydonium, which belongs to the most ancient and simple metazoan groups, the Porifera. RTKs are enzymes found only in metazoa. The sponge gene contains two introns in the extracellular part of the protein. However, the r...

journal_title：Journal of molecular evolution

authors： Gamulin V,Skorokhod A,Kavsan V,Müller IM,Müller WE

更新日期：1997-03-01 00:00:00

abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...

journal_title：Journal of molecular evolution

authors： Maruyama K,Hartl DL

更新日期：1991-12-01 00:00:00

abstract：:Pituitary prolactin, like growth hormone (GH) and several other protein hormones, shows an episodic pattern of molecular evolution in which sustained bursts of rapid change contrast with long periods of slow evolution. A period of rapid change occurred in the evolution of prolactin in primates, leading to marked seque...

journal_title：Journal of molecular evolution

authors： Wallis OC,Mac-Kwashie AO,Makri G,Wallis M

更新日期：2005-05-01 00:00:00

abstract：:A 2550-bp portion of the mitochondrial genome of a Demosponge, genus Tetilla, was amplified from whole genomic DNA extract and sequenced. The sequence was found to code for the 3' end of the 16S rRNA gene, cytochrome c oxidase subunit II, a lysine tRNA, ATPase subunit 8, and a 5' portion of ATPase subunit 6. The Porif...

journal_title：Journal of molecular evolution

authors： Watkins RF,Beckenbach AT

更新日期：1999-05-01 00:00:00

abstract：:The accuracies and efficiencies of three different methods of making phylogenetic trees from gene frequency data were examined by using computer simulation. The methods examined are UPGMA, Farris' (1972) method, and Tateno et al.'s (1982) modified Farris method. In the computer simulation eight species (or populations...

journal_title：Journal of molecular evolution

authors： Nei M,Tajima F,Tateno Y

更新日期：1983-01-01 00:00:00

abstract：:In mammals, chicken-type (c-type) lysozymes are part of the innate immune system, killing bacteria by degrading peptidoglycan in their cell walls. Many of the studies on the evolution of c-type lysozymes have focused on its new digestive function, including the duplicated stomach lysozymes in ruminants. Similarly, in ...

journal_title：Journal of molecular evolution

authors： He C,Wei Y,Zhu Y,Xia Y,Irwin DM,Liu Y

更新日期：2019-12-01 00:00:00

abstract：:With the aim of elucidating the evolutionary processes of the kringle and protease domains in serine proteases which are involved with the system of blood coagulation and fibrinolysis, we constructed phylogenetic trees for the kringle and protease domains, separately, by use of amino acid sequence data. The phylogenet...

journal_title：Journal of molecular evolution

authors： Ikeo K,Takahashi K,Gojobori T

更新日期：1995-03-01 00:00:00

abstract：:The complete sequence of the mitochondrial genome of the plant parasitic nematode Xiphinema americanum sensu stricto has been determined. At 12626bp it is the smallest metazoan mitochondrial genome reported to date. Genes are transcribed from both strands. Genes coding for 12 proteins, 2 rRNAs and 17 putative tRNAs (w...

journal_title：Journal of molecular evolution

authors： He Y,Jones J,Armstrong M,Lamberti F,Moens M

更新日期：2005-12-01 00:00:00

abstract：:Restriction modification (RM) systems serve to protect bacteria against bacteriophages. They comprise a restriction endonuclease activity that specifically cleaves DNA and a corresponding methyltransferase activity that specifically methylates the DNA, thereby protecting it from cleavage. Such systems are very common ...

journal_title：Journal of molecular evolution

authors： Jeltsch A,Pingoud A

更新日期：1996-02-01 00:00:00

abstract：:We have previously shown that several multicopy gene families within the major histocompatibility complex (MHC) arose from a process of segmental duplication. It has also been observed that retroelements play a role in generating diversity within these duplicated segments. The objective of this study was to compare th...

journal_title：Journal of molecular evolution

authors： Freitas EM,Gaudieri S,Zhang WJ,Kulski JK,van Bockxmeer FM,Christiansen FT,Dawkins RL

更新日期：2000-04-01 00:00:00

abstract：:The codon assignment of the quasi-universal genetic code can be assumed to have resulted from the evolutionary pressures that prevailed when the code was still evolving. Here, we review studies of the structure of the genetic code based on optimization models. We also review studies that, from the structure of the cod...

journal_title：Journal of molecular evolution

authors： Jestin JL,Kempf A

更新日期：2009-11-01 00:00:00