Abstract：
:One of the pupal cuticle protein (PCP) genes has been found within an intron of a Drosophila housekeeping gene (the Gart locus) that encodes three enzymes involved in the purine pathway. This intronic gene has been described as a gene within a gene, and the gene is now called a "nested" gene. Because the intronic PCP gene has sequence similarity with the larval cuticle protein (LCP) gene, it may have been derived from one of the LCP genes or their ancestral gene. We have studied possible phylogenetic relationships among these five genes by comparing nucleotide sequences of four LCP genes with that of the PCP gene. The results obtained suggest that the PCP gene may have originated from an ancestral gene before duplication of the LCP genes occurred. Using the number of synonymous (silent) substitutions, we then estimated the divergence time between the PCP gene and the LCP genes to be about 70 million years (Myr). The divergence time estimated is much larger than that for the sibling species of D. melanogaster (about 2.5 Myr), indicating that the "nested" gene structure can be seen not only in Drosophila melanogaster, but also in other distantly related Drosophila species.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Moriyama EN,Gojobori Tdoi
10.1007/BF02603074subject
Has Abstractpub_date
1989-05-01 00:00:00pages
391-7issue
5eissn
0022-2844issn
1432-1432journal_volume
28pub_type
杂志文章abstract：:The mitochondrial genome of yeast (S. cerevisiae or S. carlsbergensis) appears to be formed by 60-70 genetic units, each one of which is formed by (1) a GC-rich sequence, possibly having a regulatory role; (2) a gene, and (3) an AT-rich spacer, which probably is not transcribed. Recombination in this genome appears to...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01796120
更新日期：1976-12-31 00:00:00
abstract：:Short interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplification from one or a few evolving master genes or by (ii) the generation of new master genes that coexist with their progenitors. Individual, highly conserved, elements of the B1 SINE family were identified from t...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010087
更新日期：2000-09-01 00:00:00
abstract：:In bacteria, synonymous codon usage can be considerably affected by base composition at neighboring sites. Such context-dependent biases may be caused by either selection against specific nucleotide motifs or context-dependent mutation biases. Here we consider the evolutionary conservation of context-dependent codon b...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002399910031
更新日期：2000-03-01 00:00:00
abstract：:Previous studies have revealed a major difference in the phylogenetic structure, extent of genetic diversity, and selection pressure between the surface glycoproteins and internal gene segments of avian influenza viruses (AIV) sampled from wild birds. However, what evolutionary processes are responsible for these stri...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-009-9312-8
更新日期：2010-01-01 00:00:00
abstract：:In this study, the molecular population genetics of the orangutan's alpha-2 globin (HBA2) gene were investigated in order to test for the action of natural selection. Haplotypes from 28 orangutan chromosomes were collected from a 1.46-kilobase region of the alpha-2 globin locus. While many aspects of the data were con...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-004-0201-x
更新日期：2005-03-01 00:00:00
abstract：:Catalyzed by a family of enzymes called glycosyltransferases, glycosylation reactions are essential for the bioactivities of secondary metabolites such as antibiotics. Due to the special characters of antibiotic glycosyltransferases (AGts), antibiotics can function by attaching some unusual deoxy-sugars to their aglyc...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-006-0110-2
更新日期：2007-03-01 00:00:00
abstract：:A cDNA encoding a new member of the gene family of major royal jelly proteins (MRJPs) from the honeybee, Apis mellifera, was isolated and sequenced. Royal jelly (RJ) is a secretion of the cephalic glands of nurse bees. The origin and biological function of the protein component (12.5%, w/w) of RJ is unknown. We show t...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006551
更新日期：1999-08-01 00:00:00
abstract：:The human Rh blood group locus consists of two structurally related genes (D and CcEe) in Rh-positive haplotypes but a single gene (CcEe) in Rh-negative haplotypes. The genome of rhesus monkeys (Macaca mulatta), while not expressing any of the human Rh D, C, c, E, or e specificities, carries a Rh-like locus strongly r...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00166163
更新日期：1994-02-01 00:00:00
abstract：:The transposable element mariner occurs widely in the melanogaster species group of Drosophila. However, in drosophilids outside of the melanogaster species group, sequences showing strong DNA hybridization with mariner are found only in the genus Zaprionus. The mariner sequence obtained from Zaprionus tuberculatus is...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02102804
更新日期：1991-12-01 00:00:00
abstract：:The 70-kDa heat-shock protein (HSP70) constitutes the most conserved protein present in all organisms that is known to date. Based on global alignment of HSP70 sequences from organisms representing all three domains, numerous sequence signatures that are specific for prokaryotic and eukaryotic homologs have been ident...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00182743
更新日期：1993-12-01 00:00:00
abstract：:All complete retrovirus sequences in the GenEMBL database were examined with the goal of assessing possible relationships between the nucleotide composition of retroviral genomes, the amino acid composition of retroviral proteins, and evolutionary strategies used by retroviruses. The results demonstrated that the geno...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00178851
更新日期：1994-05-01 00:00:00
abstract：:In the plant chloroplast genome the codon usage of the highly expressed psbA gene is unique and is adapted to the tRNA population, probably due to selection for translation efficiency. In this study the role of selection on codon usage in each of the fully sequenced chloroplast genomes, in addition to Chlamydomonas re...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006325
更新日期：1998-04-01 00:00:00
abstract：:Calmodulin is a calcium-binding EF-hand protein that is an activator of many enzymes as well as ion pumps and channels. Due to its multiple targets and its central role in the cell, understanding the evolutionary history of calmodulin genes should provide insights into the origin of genetic complexity in eukaryotes. W...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010074
更新日期：2000-08-01 00:00:00
abstract：:In mammals, chicken-type (c-type) lysozymes are part of the innate immune system, killing bacteria by degrading peptidoglycan in their cell walls. Many of the studies on the evolution of c-type lysozymes have focused on its new digestive function, including the duplicated stomach lysozymes in ruminants. Similarly, in ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-019-09910-7
更新日期：2019-12-01 00:00:00
abstract：:In this study, a new strategy for the selection of aptamers against small-molecule target was established using gold nanoparticles (AuNPs) as the separation matrix and Zinc(II)-Protoporphyrin IX (ZnPPIX) as the target molecule without the immobilization step due to the absorption of ssDNA on AuNPs. The progress of the...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-019-09905-4
更新日期：2019-09-01 00:00:00
abstract：:To clarify the phylogenetic position of Vestimentifera (tube worms), 346-bp fragments of the elongation factor-1 alpha (EF-1 alpha) gene (939-1286 according to the numbering of the human gene) of a vestimentiferan, Lamellibrachia sp., a sternaspid polychaete, Sternaspis scutata, an earthworm, Pheretima sp., and a gast...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00170463
更新日期：1993-07-01 00:00:00
abstract：:Skin pigmentation is a complex, conspicuous, highly variable human trait that exhibits a remarkable correlation with latitude. The evolutionary history and genetic basis of skin color variation has been the subject of intense research in the last years. This article reviews the major hypotheses explaining skin color d...
journal_title：Journal of molecular evolution
pub_type： 杂志文章,评审
doi：10.1007/s00239-019-09902-7
更新日期：2020-01-01 00:00:00
abstract：:EcoRI restriction of the B. nigra rDNA recombinants, isolated from a lambda genomic library, showed that the 3.9-kb fragment corresponded to the Intergenic Spacer (IGS), which was sequenced and found to be 3,928 bp in size. Sequence and dot-matrix analyses showed that the organization of the B. nigra rDNA IGS was typi...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02337518
更新日期：1996-11-01 00:00:00
abstract：:Fish protamines are highly specialized molecules which are responsible for chromatin condensation during the last stages of spermatogenesis (spermiogenesis). However, not all fish contain protamines in their sperm nuclei; rather, there seems to be a random distribution of protamines within this group. The origin of th...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00160152
更新日期：1994-09-01 00:00:00
abstract：:Ca(2+)/cation antiporter (CaCA) proteins are integral membrane proteins that transport Ca(2+) or other cations using the H(+) or Na(+) gradient generated by primary transporters. The CAX (for CAtion eXchanger) family is one of the five families that make up the CaCA superfamily. CAX genes have been found in bacteria, ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-006-0048-4
更新日期：2006-12-01 00:00:00
abstract：:The mammalian defensin molecule is a short, highly cationic peptide cytotoxic to both microbial and mammalian cells which is cleaved from a precursor including a signal peptide and a highly anionic propiece. A phylogenetic analysis of 28 complete sequences from five mammalian species (mouse, rat, guinea pig, rabbit, a...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006191
更新日期：1997-06-01 00:00:00
abstract：:In order to assess the roles of gene conversion followed by natural selection and balancing selection for point mutations in polymorphisms at major histocompatibility complex (MHC) loci, DNA sequences of several mammalian taxa were analyzed. Synonymous and nonsynonymous diversities were estimated separately for the an...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF00170662
更新日期：1995-08-01 00:00:00
abstract：:Fox and Woese (1975a) have shown that a model of 5S RNA secondary structure similar to the one originally derived for Chlorella 5S RNA can be generalized with relatively minor variations to all sequenced 5S RNA molecules, i.e. that corresponding base paired regions can be formed at approximately the same positions. We...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01796136
更新日期：1977-09-20 00:00:00
abstract：:The weight-averaged observed/expected dinucleotide frequencies for the sum total of the coding regions of five Toxoplasma genes were compared with the same parameters previously determined for the coding regions of 21 Plasmodium genes. In addition, codon usage in the five Toxoplasma genes was compared with that in the...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02101892
更新日期：1990-04-01 00:00:00
abstract：:To get a better understanding of the effect of interelement selection on the variation of long terminal repeat retrotransposon families, we have investigated the evolutionary history of blood in the Drosophila melanogaster species complex. We carried out a PCR approach to amplify the 5' untranslated region from blood ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s002390010164
更新日期：2001-04-01 00:00:00
abstract：:The genome of Glycine max (L.) Merr. cv. "Dare" contains a chlorophyll a/b binding (Cab) protein gene family consisting of 10 genes. The primary structures of two linked Cab genes (Cab 4 and Cab 5) were determined. A comparison of the nucleic acid and predicted amino acid sequences of Cab 4 and Cab 5 revealed a high d...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF02100210
更新日期：1989-09-01 00:00:00
abstract：:We present two new models of protein sequence evolution based on structural properties of mitochondrial proteins. We compare these models with others currently used in phylogenetic analyses, investigating their performance over both short and long evolutionary distances. We find that our models that incorporate second...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239001-0052-7
更新日期：2002-04-01 00:00:00
abstract：:This study was designed to characterize further the nontranscribed intergenic spacers (NTSs) of the 5S rRNA genes of fish and evaluate this marker as a tool for comparative studies. Two members of the closely related North American Great Lakes cisco species complex (Coregonus artedi and C. zenithicus) were chosen for ...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/pl00006348
更新日期：1998-06-01 00:00:00
abstract：:Comparisons of the amino acid compositions of the nitrogenase proteins from different organisms and their correlation with cross-reactivities and taxonomical data suggest an evolution within bacterial genomes rather than within plasmids. Comparisons of the amino acid compositions of nitrogenases and other ATP-ases sho...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/BF01732473
更新日期：1976-03-29 00:00:00
abstract：:The genome organization of the Hardness locus in the tribe Triticeae constitutes an excellent model for studying the mechanisms of evolution that played a role in the preservation and potential functional innovations of duplicate genes. Here we applied the nonsynonymous-synonymous rate ratio (d ( N )/d ( S ) or omega)...
journal_title：Journal of molecular evolution
pub_type： 杂志文章
doi：10.1007/s00239-005-0292-z
更新日期：2006-10-01 00:00:00
