Comparison of dinucleotide frequency and codon usage in Toxoplasma and Plasmodium: evolutionary implications.

abstract：:The homeobox gene Hoxa-13 codes for a transcription factor involved in multiple functions, including body axis and hand/foot development in tetrapods. In this study we investigate whether the loss of one function (e.g., limb loss in snakes) left a molecular footprint in exon 1 of Hoxa-13 that could be associated with ...

journal_title：Journal of molecular evolution

authors： Kohlsdorf T,Cummings MP,Lynch VJ,Stopper GF,Takahashi K,Wagner GP

更新日期：2008-12-01 00:00:00

abstract：:The size and diversity of bacteriophage populations require methodologies to quantitatively study the landscape of phage differences. Statistical approaches are confronted with small genome sizes forbidding significant single-phage analysis, and comparative methods analyzing full phage genomes represent an alternative...

journal_title：Journal of molecular evolution

authors： Carbone A

更新日期：2008-03-01 00:00:00

abstract：:Abortive cycling features transcription initiation by RNA polymerase in both prokaryote and eukaryote. It is known that T7 RNA polymerase produces abortive transcripts up to eight ribonucleotides in length depending on the initial sequence of the DNA message. On the other hand, T7 RNA polymerase initiates DNA replicat...

journal_title：Journal of molecular evolution

authors： Matsumoto J

更新日期：1994-12-01 00:00:00

abstract：:Artesian groundwaters of high radionuclide concentration are ubiquitous and may have provided the large, sustained energy sources that were required to drive the multistage process of DNA and primordial cell evolution. The rapid, early development of the genetic code as well as its degeneracy can be attributed to exce...

journal_title：Journal of molecular evolution

authors： Martell EA

更新日期：1992-10-01 00:00:00

abstract：:The study of genetic evolution within the context of adaptive radiations offers insights to genes and selection pressures that result in rapid morphological change. Cichlid fishes are very species-rich and variable in coloration, behavior, and morphology, and so provide a classical model system for studying the geneti...

journal_title：Journal of molecular evolution

authors： Fan S,Elmer KR,Meyer A

更新日期：2011-08-01 00:00:00

abstract：:The diversity of functional genes and the related processes are important issues for conservation biology. This is especially relevant for populations that have suffered from demographic reduction as a consequence of the processes of postglacial colonization. In this perspective, the aims of the present study are (1) ...

journal_title：Journal of molecular evolution

authors： Girard P,Angers B

更新日期：2011-08-01 00:00:00

abstract：:Examination of the mitochondrial small subunit ribosomal RNA (rns) gene of five species of the fungal genus Leptographium revealed that the gene has been invaded at least once at position 952 by a group II intron encoding a LAGLIDADG homing endonuclease gene. Phylogenetic analyses of the intron and homing endonuclease...

journal_title：Journal of molecular evolution

authors： Mullineux ST,Willows K,Hausner G

更新日期：2011-06-01 00:00:00

abstract：:We have sequenced the nuclear and mitochondrial small subunit rRNA genes (rns) and the mitochondrial genes coding for subunits 1 and 3 of the cytochrome oxidase (cox1 and cox3, respectively) of the chytridiomycete Allomyces macrogynus. Phylogenetic trees inferred from the derived COX1 and COX3 proteins and the nuclear...

journal_title：Journal of molecular evolution

authors： Paquin B,Forget L,Roewer I,Lang BF

更新日期：1995-11-01 00:00:00

abstract：:Darwinian theory requires that mutations be produced in a nonanticipatory manner; it is nonetheless consistent to suggest that mutations that have repeatedly led to nonviable phenotypes would be introduced less frequently than others-if under appropriate genetic control. Immunoglobulins produced during infection acqui...

journal_title：Journal of molecular evolution

authors： Cowell LG,Kim HJ,Humaljoki T,Berek C,Kepler TB

更新日期：1999-07-01 00:00:00

abstract：:The efficiency of obtaining the correct tree by the maximum likelihood method (Felsenstein 1981) for inferring trees from DNA sequence data was compared with trees obtained by distance methods. It was shown that the maximum likelihood method is superior to distance methods in the efficiency particularly when the evolu...

journal_title：Journal of molecular evolution

authors： Hasegawa M,Kishino H,Saitou N

更新日期：1991-05-01 00:00:00

abstract：:Amino acid substitution models represent substitution rates among amino acids during the evolution. The models play an important role in analyzing protein sequences, especially inferring phylogenies. The rapid evolution of flaviviruses is expanding the threat in public health. A number of models have been estimated fo...

journal_title：Journal of molecular evolution

authors： Le TK,Vinh LS

更新日期：2020-07-01 00:00:00

abstract：:We provide here evidence for a conserved regulatory element for transcription of the β-family globin genes based on a comparative study of 32 genes from 16 mammals. The element is characterized by the appearance of AA or TT dinucleotides in the A + T-rich region located 200-400 bp upstream of the cap sites. G-tracts 3...

journal_title：Journal of molecular evolution

authors： Kiyama R,Wada-Kiyama Y

更新日期：2011-10-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) restriction site maps for nine species of the Drosophila obscura subgroup and for Drosophila melanogaster were established. Taking into account all restriction enzymes (12) and strains (45) analyzed, a total of 105 different sites were detected, which corresponds to a sample of 3.49% of the m...

journal_title：Journal of molecular evolution

authors： González AM,Hernández M,Volz A,Pestano J,Larruga JM,Sperlich D,Cabrera VM

更新日期：1990-08-01 00:00:00

abstract：:Since their discovery in Metazoa, the three nuclear RNA polymerases (RNAPs) have been found in fungi, plants, and diverse protists. In all eukaryotes studied to date, RNAPs I, II, and III collectively transcribe all major RNAs made in the nucleus. We have found genes for the largest subunit (RPD1/RPE1) of a new DNA-de...

journal_title：Journal of molecular evolution

authors： Luo J,Hall BD

更新日期：2007-01-01 00:00:00

abstract：:The Pten gene was initially identified in humans as a tumor suppressor. It has since been shown to play important roles in the control of cell size, cell motility, apoptosis, and organ size, and it has also been implicated in aging. Pten is highly conserved among organisms as diverse as nematodes, insects, and vertebr...

journal_title：Journal of molecular evolution

authors： Baudry E,Desmadril M,Werren JH

更新日期：2006-06-01 00:00:00

abstract：:One crucial event during evolution to multicellularity was the development of either direct cell-cell contact or indirect interaction via extracellular matrix (ECM) molecules. The identification of those polypeptides provides conclusive data on the phylogenetic relationship of metazoan phyla and helps us to understand...

journal_title：Journal of molecular evolution

authors： Schütze J,Skorokhod A,Müller IM,Müller WE

更新日期：2001-10-01 00:00:00

abstract：:The present work represents the first attempt to study in greater detail previously proposed compositional correlations in genomes, based on a body of additional data relating to gene localizations as well as to extended flanking sequences extracted from gene banks. We have investigated the correlations that exist bet...

journal_title：Journal of molecular evolution

authors： Aïssani B,D'Onofrio G,Mouchiroud D,Gardiner K,Gautier C,Bernardi G

更新日期：1991-06-01 00:00:00

abstract：:The neutral theory of molecular evolution states that most mutations are deleterious or neutral. It results that the evolutionary rate of a given position in an alignment is a function of the level of constraint acting on this position. Inferring evolutionary rates from a set of aligned sequences is hence a powerful m...

journal_title：Journal of molecular evolution

authors： Dutheil J

更新日期：2008-09-01 00:00:00

abstract：:Analysis of the expanded data set of Sibley and Ahlquist (1987) on primate phylogeny using a maximum likelihood mixed model analysis of variance method shows that there is significant evidence for resolving the Homo-Pan-Gorilla trifurcation in favor of a Homo-Pan clade. The resulting tree is close to that estimated by...

journal_title：Journal of molecular evolution

authors： Felsenstein J

更新日期：1987-01-01 00:00:00

abstract：:Spermatogenesis is one of the most complex biological processes undergone by any organism, making it susceptible to perturbations that result in male sterility. Research has demonstrated that mutant phenotypes can be obtained from the disruption of epigenetic modifications, which are commonly microRNA guided. Employin...

journal_title：Journal of molecular evolution

authors： Madison-Villar MJ,Michalak P

更新日期：2011-12-01 00:00:00

abstract：:One of the key problems in the study of ancient DNA is that of authenticating sequences obtained from PCR amplifications of highly degraded samples. Contamination of ancient samples and postmortem damage to endogenous DNA templates are the major obstacles facing researchers in this task. In particular, the authenticat...

journal_title：Journal of molecular evolution

authors： Helgason A,Pálsson S,Lalueza-Fox C,Ghosh S,Sigurdardóttir S,Baker A,Hrafnkelsson B,Arnadóttir L,Thorsteinsdóttir U,Stefánsson K

更新日期：2007-07-01 00:00:00

abstract：:HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become avai...

journal_title：Journal of molecular evolution

authors： Griess EA,Rensing SA,Grasser KD,Maier UG,Feix G

更新日期：1993-08-01 00:00:00

abstract：:The mammalian defensin molecule is a short, highly cationic peptide cytotoxic to both microbial and mammalian cells which is cleaved from a precursor including a signal peptide and a highly anionic propiece. A phylogenetic analysis of 28 complete sequences from five mammalian species (mouse, rat, guinea pig, rabbit, a...

journal_title：Journal of molecular evolution

authors： Hughes AL,Yeager M

更新日期：1997-06-01 00:00:00

abstract：:We report the sequence of A/B.L1, a tightly linked pair of genes from the A and B chorion families in Bombyx mori. Comparison with the previously characterized A/B.L11 and A/B.L12 pairs from the same species reveals moderate sequence divergence, which is clearly nonuniform. Although the average divergence of A/B.L12 f...

journal_title：Journal of molecular evolution

authors： Tsitilou SG,Kafatos FC

更新日期：1989-11-01 00:00:00

abstract：:We describe the complete mitochondrial genome of the house centipede Scutigera coleoptrata. Its gene order is unique among characterized arthropod mitochondrial genomes. Comparison to the gene order in the horseshoe crab mtDNA implies 10 or more translocations. By extending comparisons to 30 arthropod mitochondrial ge...

journal_title：Journal of molecular evolution

authors： Negrisolo E,Minelli A,Valle G

更新日期：2004-04-01 00:00:00

abstract：:We have performed a genome-wide analysis of the mimp family of miniature inverted-repeat transposable elements, taking advantage of the recent release of the F. oxysporum genome sequence. Using different approaches, we detected 103 mimp elements, corresponding to 75 nonredundant copies, half of which are located on a ...

journal_title：Journal of molecular evolution

authors： Bergemann M,Lespinet O,M'Barek SB,Daboussi MJ,Dufresne M

更新日期：2008-12-01 00:00:00

abstract：:We have further characterized the Asian genotypes (Types 2 and 7) and subtypes of JC virus (JCV). Urine samples from 224 individuals with Han and Mongolian populations were collected in five regions in eastern China: Kunming, Chengdu, Shenyang, Chifeng, and Manzhouli. Also, 99 urine samples were collected from coastal...

journal_title：Journal of molecular evolution

authors： Cui X,Wang JC,Deckhut A,Joseph BC,Eberwein P,Cubitt CL,Ryschkewitsch CF,Agostini HT,Stoner GL

更新日期：2004-05-01 00:00:00

abstract：:Phospholipid vesicles (liposomes) were subjected to dehydration-hydration cycles in the presence of 6-carboxyfluorescein or salmon sperm DNA. We found that the vesicles fused into multilamellar structures during dehydration with solutes trapped between the lamellae. Upon rehydration the lamellae swelled and formed lar...

journal_title：Journal of molecular evolution

authors： Deamer DW,Barchfeld GL

更新日期：1982-01-01 00:00:00

abstract：:Four genes in the P450 IID gene subfamily were isolated from Sprague-Dawley rat lambda EMBL 3 and Charon 4A genomic libraries and completely sequenced. Their transcription start sites were determined by primer extension analysis. The four genes designated IID2, IID3, IID4, and IID5 span 4036, 4371, 4678, and 4567 bp, ...

journal_title：Journal of molecular evolution

authors： Matsunaga E,Umeno M,Gonzalez FJ

更新日期：1990-02-01 00:00:00

abstract：:The specificity of interaction of amino acids with triplets in the acceptor helix stem of tRNA was investigated by means of a statistical analysis of 1400 tRNA sequences. The imprint of a prototypic genetic code at position 3-5 of the acceptor helix was detected, but only for those major amino acids, glycine, alanine,...

journal_title：Journal of molecular evolution

authors： Möller W,Janssen GM

更新日期：1992-06-01 00:00:00