Abstract:
:Analysis of the expanded data set of Sibley and Ahlquist (1987) on primate phylogeny using a maximum likelihood mixed model analysis of variance method shows that there is significant evidence for resolving the Homo-Pan-Gorilla trifurcation in favor of a Homo-Pan clade. The resulting tree is close to that estimated by Sibley and Ahlquist (1984). The mixed model can be used to test a number of hypotheses about the existence of components of variance and the linearity of the relationship between branch length and expected distance. No evidence is found that there is a variance component for extract, or for the individual from which the extract was taken. A variance component for experiment does seem to exist, presumably arising as a result of error of measurement of the common standard from which all values in the same experiment were subtracted. There is significant evidence that the relationship between total branch length between species and their expected distances is nonlinear, or else that the measurement error on larger distances is greater than on smaller ones. Allowing for the nonlinearity might cause one to infer the time of distant common ancestors as less remote than the measured hybridization values would imply if used directly.
journal_name
J Mol Evoljournal_title
Journal of molecular evolutionauthors
Felsenstein Jdoi
10.1007/BF02111286subject
Has Abstractpub_date
1987-01-01 00:00:00pages
123-31issue
1-2eissn
0022-2844issn
1432-1432journal_volume
26pub_type
杂志文章abstract::We have performed DNA-DNA hybridization experiments among several species of Drosophila using the evolutionarily conserved portion of the genome representing sequences coding for amino acids of proteins. This was done by using as tracer, radioactively labeled complementary DNA that was reverse transcribed from adult m...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00182390
更新日期:1992-02-01 00:00:00
abstract::Previous studies have revealed a major difference in the phylogenetic structure, extent of genetic diversity, and selection pressure between the surface glycoproteins and internal gene segments of avian influenza viruses (AIV) sampled from wild birds. However, what evolutionary processes are responsible for these stri...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-009-9312-8
更新日期:2010-01-01 00:00:00
abstract::The symbiotic protists of the lower termite have been regarded as a model of early-branched eukaryotes because of their simple cellular systems and morphological features. However, cultivation of these symbiotic protists is very difficult. For this reason, these interesting protists have not been well characterized in...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010129
更新日期:2001-01-01 00:00:00
abstract::Microsatellite DNA sequences have become the dominant source of nuclear genetic markers for most applications. It is important to investigate the basis of variation between alleles and to know if current assumptions about the mechanisms of microsatellite mutation (that is to say, variations involving simple changes in...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006151
更新日期:1997-03-01 00:00:00
abstract::Variation in structure among primate hemoglobins is associated with variation in function. This supports the hypothesis that most substitutions observed among homologous proteins in different species have been fixed by natural selection because they contribute to the fitness of the genotype. It does not support the co...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01653958
更新日期:1972-12-01 00:00:00
abstract::We obtained and studied HIV-1 sequences with a known sampling year from three outbreaks of the HIV-1 epidemic: 141 env V3 (270 nt) sampled between 1984 and 1992 and 117 pol prot/RT (804 nt) sequences sampled between 1986 and 1999 from Dutch homosexual men and injecting drug users (IDUs), as well as 77 env V3 sequences...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-001-0070-5
更新日期:2002-05-01 00:00:00
abstract::Single likelihood ancestor counting (SLAC), fixed effects likelihood (FEL), and several random effects likelihood (REL) methods were utilized to identify positively and negatively selected sites in sexually induced gene 1 (Sig1) of four different Thalassiosira species. The SLAC analysis did not find any sites affected...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-006-0016-z
更新日期:2006-08-01 00:00:00
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journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010101
更新日期:2000-10-01 00:00:00
abstract::It has been argued that the common ancestor of about 75% of all dicots possessed an S-RNase-based gametophytic self-incompatibility (GSI) system. S-RNase genes should thus be found in most plant families showing GSI. The S-RNase gene (or a duplicate) may also acquire a new function and thus genes belonging to the S-RN...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-008-9137-x
更新日期:2008-08-01 00:00:00
abstract::In this work detailed statistics on ancestral gene duplication and gene conservation in completely sequenced cellular genomes are presented. Analysis of open reading frame (ORF) products having simultaneous matches in several distinct organisms showed a significant correlation between duplication and conservation. Sys...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006580
更新日期:1999-11-01 00:00:00
abstract::The relaxin (RLN) and insulin-like (INSL) gene family is a group of genes involved in a variety of physiological roles that includes bone formation, testicular descent, trophoblast development, and cell differentiation. This family appears to have expanded in vertebrates relative to non-vertebrate chordates, but the r...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-010-9403-6
更新日期:2011-01-01 00:00:00
abstract::The evolutionary relationships of four eukaryotic kingdoms--Animalia, Plantae, Fungi, and Protista--remain unclear. In particular, statistical support for the closeness of animals to fungi rather than to plants is lacking, and a preferred branching order of these and other eukaryotic lineages is still controversial ev...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02198844
更新日期:1996-02-01 00:00:00
abstract::Oxygen-free aqueous solutions of NH4CN (0.1 M, pH9) were exposed to gamma rays from a 60Co source, the mixture of nonvolatile products was fractionated, and the fractions were analyzed. The procedures were chosen to make effective investigations of radiolytic products, and to minimize the contributions of chemical cha...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF01732951
更新日期:1980-07-01 00:00:00
abstract::Minerals may have played a significant role in chemical evolution. In the course of investigating the chemistry of phosphonoacetaldehyde (PAL), an analogue of glycolaldehyde phosphate, we have observed a striking case of catalysis by the layered hydroxide mineral hydrotalcite ([Mg2Al(OH)6][Cl.nH2O]). In neutral or mod...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/pl00006406
更新日期:1998-11-01 00:00:00
abstract::Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010049
更新日期:2000-05-01 00:00:00
abstract::Phylogenetic relationships of 25 mammalian species representing 17 of the 18 eutherian orders were examined using DNA sequences from a 1.2-kb region of the 5' end of exon 1 of the single-copy nuclear gene known as interphotoreceptor retinoid binding protein (IRBP). A wide variety of methods of analysis of the DNA sequ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02337352
更新日期:1996-08-01 00:00:00
abstract::Studies during the last 20 years have shown that the chromosomes of many organisms, especially those of higher vertebrates, consist of a series of segments having different properties. These can be recognized as, for example, G- and R-bands. Recent studies have indicated that genes tend to lie in the R-bands rather th...
journal_title:Journal of molecular evolution
pub_type: 杂志文章,评审
doi:10.1007/BF02407346
更新日期:1993-08-01 00:00:00
abstract::The trnT-trnF region is located in the large single-copy region of the chloroplast genome. It consists of the trnL intron, a group I intron, and the trnT-trnL and trnL-trnF intergenic spacers. We analyzed the evolution of the region in the three genera of the gymnosperm lineage Gnetales (Gnetum, Welwitschia, and Ephed...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-004-0240-3
更新日期:2005-10-01 00:00:00
abstract::Prediction of the thermodynamic behaviors of biomolecules at high temperature and pressure is fundamental to understanding the role of hydrothermal systems in the origin and evolution of life on the primitive Earth. However, available thermodynamic dataset for amino acids, essential components for life, cannot represe...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-014-9616-1
更新日期:2014-04-01 00:00:00
abstract::Cytochrome proteins perform a broad spectrum of biological functions ranging from oxidative metabolism to electron transport and are thus essential to all organisms. The b-type cytochrome proteins bind heme noncovalently, are expressed in many different forms and are localized to various cellular compartments. We repo...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00160314
更新日期:1995-10-01 00:00:00
abstract::We have further characterized the Asian genotypes (Types 2 and 7) and subtypes of JC virus (JCV). Urine samples from 224 individuals with Han and Mongolian populations were collected in five regions in eastern China: Kunming, Chengdu, Shenyang, Chifeng, and Manzhouli. Also, 99 urine samples were collected from coastal...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-003-2579-2
更新日期:2004-05-01 00:00:00
abstract::The mitochondrial cytochrome b (cyt-b) gene is widely used in systematic studies to resolve divergences at many taxonomic levels. The present study focuses mainly on the utility of cyt-b as a molecular marker for inferring phylogenetic relationship at various levels within the fish family Cichlidae. A total of 78 taxa...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010197
更新日期:2001-08-01 00:00:00
abstract::This paper presents an essentially new method used to construct phylogenetic trees from related amino acid sequences. The method is based on a new distance measure which describes sequence relationships by means of typical steric and physicochemical properties of the amino acids and is advantageous in some essential p...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00160324
更新日期:1995-10-01 00:00:00
abstract::Antibody binding site are formed by six hypervariable regions or complementarity determining regions (CDRs). The CDRs, three from the heavy chain and three from the light chain, are known as hypervariable segments and provide a surface complementary to that of the epitope. In recent work it was found that the amino ac...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00175497
更新日期:1994-01-01 00:00:00
abstract::The availability of fast and accurate sequencing procedures along with the use of PCR has led to a proliferation of studies of variability at the molecular level in populations. Nevertheless, it is often impractical to examine long genomic stretches and a large number of individuals at the same time. In order to optim...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF00173194
更新日期:1995-12-01 00:00:00
abstract::This study investigated the evolution of a transition metal ion-binding cluster ([H--X--X--X--H](n); Tx) in the alternatively spliced NH(2)-terminal variable region of avian pectoral muscle troponin T (TnT). Encoded by avian fast skeletal muscle TnT-specific P exons, Tx-like structures were expressed in the breast mus...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s002390010139
更新日期:2001-02-01 00:00:00
abstract::Twenty-seven protein sequence elements, six to nine amino acids long, were extracted from 15 phylogenetically diverse complete prokaryotic proteomes. The elements are present in all of these proteomes, with at least one copy each (omnipresent elements), and have presumably been conserved since the last universal commo...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-007-9032-x
更新日期:2007-12-01 00:00:00
abstract::Frugivorous and nectarivorous bats rely largely on hepatic glycogenesis and glycogenolysis for postprandial blood glucose disposal and maintenance of glucose homeostasis during short time starvation, respectively. The glycogen synthase 2 encoded by the Gys2 gene plays a critical role in liver glycogen synthesis. To te...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/s00239-013-9600-1
更新日期:2014-01-01 00:00:00
abstract::Restriction modification (RM) systems serve to protect bacteria against bacteriophages. They comprise a restriction endonuclease activity that specifically cleaves DNA and a corresponding methyltransferase activity that specifically methylates the DNA, thereby protecting it from cleavage. Such systems are very common ...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02198833
更新日期:1996-02-01 00:00:00
abstract::The organization of histone gene clusters of the duck Cairina moschata was studied in the DNA inserts of two recombinant phage that overlap and feature identical histone gene arrangements but differ in sequence details and in the extent of repetition of an AT-rich motif in one of the nontranscribed spacer regions. The...
journal_title:Journal of molecular evolution
pub_type: 杂志文章
doi:10.1007/BF02102477
更新日期:1989-03-01 00:00:00