Encapsulation of macromolecules by lipid vesicles under simulated prebiotic conditions.

Abstract:

:Phospholipid vesicles (liposomes) were subjected to dehydration-hydration cycles in the presence of 6-carboxyfluorescein or salmon sperm DNA. We found that the vesicles fused into multilamellar structures during dehydration with solutes trapped between the lamellae. Upon rehydration the lamellae swelled and formed large vesicular structures containing solute. This model can be used to study encapsulation of macromolecules by lipid membranes to form protocellular structures under prebiotic conditions.

journal_name

J Mol Evol

authors

Deamer DW,Barchfeld GL

doi

10.1007/BF01733047

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

203-6

issue

3

eissn

0022-2844

issn

1432-1432

journal_volume

18

pub_type

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